Drosophila melanogaster

33 known processes

fax (Dmel_CG4609)

failed axon connections

(Aliases: Fax,CG4609,clone 1.34,anon-EST:Liang-1.34,anon-WO0172774.68,anon-WO0172774.69,fac,anon-WO0172774.65,anon-WO0172774.66,anon-WO0172774.67,Dmel\CG4609,anon-WO0172774.62,anon-WO0172774.63)

fax biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neurological system process GO:0050877 358 0.303
regulation of gene expression epigenetic GO:0040029 128 0.292
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.274
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.250
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.219
axonogenesis GO:0007409 290 0.210
positive regulation of cellular biosynthetic process GO:0031328 316 0.207
negative regulation of gene expression GO:0010629 387 0.185
dendrite development GO:0016358 204 0.183
negative regulation of rna biosynthetic process GO:1902679 240 0.181
response to abiotic stimulus GO:0009628 341 0.175
neuron projection guidance GO:0097485 241 0.171
dendrite morphogenesis GO:0048813 199 0.159
negative regulation of cellular biosynthetic process GO:0031327 277 0.153
negative regulation of transcription dna templated GO:0045892 237 0.150
negative regulation of rna metabolic process GO:0051253 251 0.147
neuron recognition GO:0008038 101 0.143
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.143
axon guidance GO:0007411 233 0.142
positive regulation of nucleic acid templated transcription GO:1903508 266 0.130
intracellular transport GO:0046907 228 0.123
positive regulation of macromolecule metabolic process GO:0010604 405 0.122
embryonic development via the syncytial blastoderm GO:0001700 148 0.122
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.115
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.112
negative regulation of cellular metabolic process GO:0031324 382 0.105
adult behavior GO:0030534 137 0.104
positive regulation of gene expression GO:0010628 290 0.100
sensory perception GO:0007600 196 0.098
positive regulation of transcription dna templated GO:0045893 266 0.097
imaginal disc derived appendage development GO:0048737 399 0.096
sensory organ morphogenesis GO:0090596 260 0.094
camera type eye development GO:0043010 4 0.092
negative regulation of nucleic acid templated transcription GO:1903507 240 0.087
gene silencing by rna GO:0031047 57 0.082
positive regulation of rna metabolic process GO:0051254 271 0.081
negative regulation of biosynthetic process GO:0009890 277 0.080
regulation of cell development GO:0060284 215 0.078
regulation of multicellular organismal development GO:2000026 414 0.076
single organism behavior GO:0044708 391 0.074
embryo development ending in birth or egg hatching GO:0009792 152 0.074
positive regulation of cellular component organization GO:0051130 156 0.067
immune system process GO:0002376 347 0.062
tissue morphogenesis GO:0048729 297 0.060
forebrain development GO:0030900 2 0.060
appendage morphogenesis GO:0035107 397 0.059
positive regulation of rna biosynthetic process GO:1902680 266 0.059
sensory perception of mechanical stimulus GO:0050954 72 0.057
positive regulation of response to external stimulus GO:0032103 44 0.057
embryonic morphogenesis GO:0048598 206 0.056
positive regulation of biosynthetic process GO:0009891 316 0.056
learning or memory GO:0007611 141 0.056
response to wounding GO:0009611 94 0.056
muscle organ development GO:0007517 127 0.055
memory GO:0007613 94 0.054
gene silencing GO:0016458 138 0.053
epithelial cell differentiation GO:0030855 322 0.052
axon development GO:0061564 297 0.051
intracellular signal transduction GO:0035556 300 0.050
regulation of cell proliferation GO:0042127 163 0.049
positive regulation of developmental process GO:0051094 143 0.049
organonitrogen compound metabolic process GO:1901564 318 0.048
regulation of immune system process GO:0002682 176 0.048
cell recognition GO:0008037 102 0.048
stem cell differentiation GO:0048863 117 0.048
regulation of intracellular signal transduction GO:1902531 236 0.047
posttranscriptional regulation of gene expression GO:0010608 145 0.044
regulation of response to stress GO:0080134 200 0.044
wound healing GO:0042060 75 0.044
response to temperature stimulus GO:0009266 106 0.044
long term memory GO:0007616 62 0.043
retina development in camera type eye GO:0060041 4 0.043
response to organic substance GO:0010033 284 0.042
regulation of cell differentiation GO:0045595 302 0.041
heterocycle catabolic process GO:0046700 166 0.041
telencephalon development GO:0021537 2 0.038
apoptotic process GO:0006915 159 0.038
regulation of cell cycle GO:0051726 291 0.038
sensory perception of sound GO:0007605 56 0.037
regulation of response to external stimulus GO:0032101 115 0.037
regulation of programmed cell death GO:0043067 152 0.037
lateral inhibition GO:0046331 206 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.035
taxis GO:0042330 304 0.035
wing disc morphogenesis GO:0007472 344 0.034
response to decreased oxygen levels GO:0036293 58 0.034
synaptic transmission GO:0007268 288 0.034
regulation of nervous system development GO:0051960 248 0.034
appendage development GO:0048736 401 0.034
spindle organization GO:0007051 253 0.034
immune effector process GO:0002252 98 0.034
endocytosis GO:0006897 310 0.033
endomembrane system organization GO:0010256 119 0.033
translation GO:0006412 69 0.032
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.032
regulation of anatomical structure morphogenesis GO:0022603 242 0.032
vesicle mediated transport GO:0016192 381 0.032
male gamete generation GO:0048232 201 0.032
protein localization GO:0008104 284 0.031
striated muscle tissue development GO:0014706 27 0.031
regulation of neurogenesis GO:0050767 158 0.031
programmed cell death GO:0012501 257 0.030
actin cytoskeleton organization GO:0030036 206 0.030
eye development GO:0001654 323 0.030
regulation of localization GO:0032879 275 0.030
posttranscriptional gene silencing by rna GO:0035194 45 0.030
aromatic compound catabolic process GO:0019439 166 0.029
post embryonic appendage morphogenesis GO:0035120 385 0.029
regulation of catabolic process GO:0009894 170 0.029
ovarian follicle cell development GO:0030707 248 0.028
skeletal muscle organ development GO:0060538 48 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.028
organic cyclic compound catabolic process GO:1901361 168 0.028
cellular protein localization GO:0034613 160 0.027
midgut development GO:0007494 23 0.027
catabolic process GO:0009056 409 0.027
mitotic spindle organization GO:0007052 220 0.026
negative regulation of cell differentiation GO:0045596 143 0.026
regulation of cellular catabolic process GO:0031329 157 0.026
wnt signaling pathway GO:0016055 98 0.026
organic substance transport GO:0071702 257 0.026
mitotic nuclear division GO:0007067 213 0.026
motor neuron axon guidance GO:0008045 58 0.025
gene silencing by mirna GO:0035195 22 0.025
protein modification by small protein conjugation GO:0032446 79 0.025
negative regulation of gene expression epigenetic GO:0045814 77 0.025
regionalization GO:0003002 416 0.025
myoblast fusion GO:0007520 43 0.025
cell proliferation GO:0008283 299 0.024
cognition GO:0050890 141 0.024
spermatogenesis GO:0007283 200 0.024
regulation of cellular protein metabolic process GO:0032268 243 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.023
chemotaxis GO:0006935 249 0.023
negative regulation of developmental process GO:0051093 201 0.023
salivary gland development GO:0007431 162 0.023
protein ubiquitination GO:0016567 70 0.023
growth GO:0040007 359 0.023
cation homeostasis GO:0055080 51 0.023
gland development GO:0048732 191 0.023
imaginal disc derived appendage morphogenesis GO:0035114 395 0.022
inter male aggressive behavior GO:0002121 60 0.022
regeneration GO:0031099 16 0.022
single organism intracellular transport GO:1902582 207 0.022
phagocytosis GO:0006909 215 0.022
response to radiation GO:0009314 155 0.022
cytoplasmic transport GO:0016482 130 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
regulation of wnt signaling pathway GO:0030111 68 0.021
localization of cell GO:0051674 257 0.021
aggressive behavior GO:0002118 63 0.021
protein complex disassembly GO:0043241 36 0.021
nucleotide catabolic process GO:0009166 109 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
exocrine system development GO:0035272 162 0.020
chromatin silencing GO:0006342 76 0.020
rna processing GO:0006396 147 0.020
single organism catabolic process GO:0044712 228 0.020
transcription from rna polymerase ii promoter GO:0006366 368 0.020
muscle structure development GO:0061061 224 0.020
regulation of synapse assembly GO:0051963 94 0.020
peripheral nervous system development GO:0007422 52 0.020
cell death GO:0008219 279 0.020
morphogenesis of embryonic epithelium GO:0016331 94 0.019
negative regulation of signal transduction GO:0009968 206 0.019
cellular nitrogen compound catabolic process GO:0044270 165 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
macromolecular complex assembly GO:0065003 256 0.019
organonitrogen compound catabolic process GO:1901565 128 0.019
chorion containing eggshell formation GO:0007304 105 0.019
digestive tract development GO:0048565 149 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.019
positive regulation of signal transduction GO:0009967 223 0.019
amine metabolic process GO:0009308 12 0.018
negative regulation of protein processing GO:0010955 31 0.018
regulation of catalytic activity GO:0050790 185 0.018
response to heat GO:0009408 63 0.018
response to hypoxia GO:0001666 53 0.018
chromosome organization GO:0051276 360 0.018
immune response activating signal transduction GO:0002757 2 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
purine nucleoside metabolic process GO:0042278 127 0.018
central nervous system development GO:0007417 201 0.018
regulation of defense response GO:0031347 102 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.018
cellular homeostasis GO:0019725 80 0.018
cellular ketone metabolic process GO:0042180 24 0.018
small molecule metabolic process GO:0044281 305 0.018
regulation of molecular function GO:0065009 217 0.018
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.017
jak stat cascade GO:0007259 49 0.017
posttranscriptional gene silencing GO:0016441 46 0.017
organic substance catabolic process GO:1901575 308 0.017
cardiovascular system development GO:0072358 82 0.017
cellular catabolic process GO:0044248 372 0.017
negative regulation of cellular protein metabolic process GO:0032269 85 0.017
negative regulation of signaling GO:0023057 219 0.017
regulation of mrna metabolic process GO:1903311 72 0.017
ion homeostasis GO:0050801 55 0.017
response to extracellular stimulus GO:0009991 116 0.017
response to lipopolysaccharide GO:0032496 4 0.017
positive regulation of signaling GO:0023056 243 0.017
death GO:0016265 284 0.017
nucleobase containing small molecule metabolic process GO:0055086 174 0.017
regulation of mitotic cell cycle GO:0007346 190 0.016
detection of stimulus GO:0051606 156 0.016
wing disc pattern formation GO:0035222 66 0.016
chromosome segregation GO:0007059 157 0.016
regulation of mrna processing GO:0050684 71 0.016
organophosphate catabolic process GO:0046434 112 0.016
immune response GO:0006955 246 0.016
cellular metal ion homeostasis GO:0006875 31 0.016
nucleoside triphosphate catabolic process GO:0009143 108 0.016
non canonical wnt signaling pathway GO:0035567 8 0.016
regulation of circadian rhythm GO:0042752 49 0.016
golgi organization GO:0007030 66 0.016
actomyosin structure organization GO:0031032 56 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.016
regulation of cell death GO:0010941 173 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
nucleoside phosphate catabolic process GO:1901292 110 0.016
homeostatic process GO:0042592 199 0.016
purine containing compound metabolic process GO:0072521 155 0.016
regulation of neuron differentiation GO:0045664 103 0.016
glycosyl compound catabolic process GO:1901658 112 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016
mrna metabolic process GO:0016071 124 0.015
purine nucleoside triphosphate catabolic process GO:0009146 108 0.015
synaptic vesicle transport GO:0048489 50 0.015
negative regulation of cellular component organization GO:0051129 108 0.015
spindle elongation GO:0051231 83 0.015
negative regulation of catalytic activity GO:0043086 42 0.015
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
wing disc dorsal ventral pattern formation GO:0048190 47 0.015
g protein coupled receptor signaling pathway GO:0007186 136 0.015
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
epithelial cell development GO:0002064 274 0.015
ras protein signal transduction GO:0007265 88 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
regulation of transport GO:0051049 181 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
regulation of hydrolase activity GO:0051336 97 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
cellular response to external stimulus GO:0071496 66 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
organophosphate metabolic process GO:0019637 195 0.015
rrna processing GO:0006364 3 0.015
body morphogenesis GO:0010171 2 0.015
muscle tissue development GO:0060537 30 0.015
negative regulation of cell death GO:0060548 81 0.014
centrosome duplication GO:0051298 121 0.014
purine containing compound catabolic process GO:0072523 112 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
protein k48 linked ubiquitination GO:0070936 3 0.014
digestive system development GO:0055123 149 0.014
muscle attachment GO:0016203 36 0.014
epidermal growth factor receptor signaling pathway GO:0007173 58 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
erbb signaling pathway GO:0038127 58 0.014
positive regulation of cell development GO:0010720 61 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
tube morphogenesis GO:0035239 191 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
antimicrobial peptide production GO:0002775 46 0.014
hindbrain development GO:0030902 2 0.014
single organism biosynthetic process GO:0044711 206 0.014
regulation of cell cycle process GO:0010564 181 0.014
locomotory behavior GO:0007626 176 0.014
circulatory system development GO:0072359 82 0.013
synaptic growth at neuromuscular junction GO:0051124 119 0.013
ribose phosphate metabolic process GO:0019693 145 0.013
regulation of chromosome organization GO:0033044 64 0.013
organic acid metabolic process GO:0006082 103 0.013
pigment metabolic process GO:0042440 84 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
regulation of behavior GO:0050795 75 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
cellular response to organic substance GO:0071310 132 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
negative regulation of catabolic process GO:0009895 36 0.013
regulation of cell shape GO:0008360 113 0.013
gliogenesis GO:0042063 80 0.013
proteolysis GO:0006508 192 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
salivary gland morphogenesis GO:0007435 145 0.013
gtp metabolic process GO:0046039 72 0.013
formation of anatomical boundary GO:0048859 37 0.013
morphogenesis of a polarized epithelium GO:0001738 93 0.013
regulation of apoptotic process GO:0042981 130 0.013
centrosome cycle GO:0007098 137 0.013
compound eye morphogenesis GO:0001745 249 0.012
head development GO:0060322 135 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
imaginal disc pattern formation GO:0007447 91 0.012
stem cell fate commitment GO:0048865 25 0.012
actin filament based process GO:0030029 220 0.012
glial cell migration GO:0008347 31 0.012
cellular amide metabolic process GO:0043603 80 0.012
camera type eye morphogenesis GO:0048593 2 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
negative regulation of cellular catabolic process GO:0031330 34 0.012
response to oxygen levels GO:0070482 59 0.012
stem cell development GO:0048864 79 0.012
positive regulation of catabolic process GO:0009896 105 0.012
rhythmic process GO:0048511 106 0.012
semaphorin plexin signaling pathway GO:0071526 4 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
striated muscle cell differentiation GO:0051146 90 0.012
regulation of endocytosis GO:0030100 37 0.012
negative regulation of growth GO:0045926 84 0.012
meiotic nuclear division GO:0007126 151 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.012
response to mechanical stimulus GO:0009612 28 0.012
biological adhesion GO:0022610 138 0.012
regulation of immune response GO:0050776 118 0.012
convergent extension involved in gastrulation GO:0060027 2 0.012
mesenchymal cell development GO:0014031 1 0.012
nucleoside catabolic process GO:0009164 112 0.012
regulation of organ morphogenesis GO:2000027 78 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
positive regulation of cell migration GO:0030335 2 0.011
stem cell maintenance GO:0019827 67 0.011
antimicrobial humoral response GO:0019730 99 0.011
response to paraquat GO:1901562 4 0.011
chromatin organization GO:0006325 207 0.011
negative regulation of cell communication GO:0010648 223 0.011
nuclear division GO:0000280 332 0.011
blood circulation GO:0008015 26 0.011
intracellular protein transport GO:0006886 104 0.011
organelle fission GO:0048285 340 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
regulation of cellular protein catabolic process GO:1903362 44 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
gland morphogenesis GO:0022612 145 0.011
syncytium formation GO:0006949 43 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
guanosine containing compound catabolic process GO:1901069 74 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.011
regulation of organelle organization GO:0033043 196 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
response to other organism GO:0051707 293 0.011
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.011
axon choice point recognition GO:0016198 26 0.011
ncrna metabolic process GO:0034660 43 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
positive regulation of cell proliferation GO:0008284 47 0.010
developmental growth GO:0048589 280 0.010
chemical homeostasis GO:0048878 92 0.010
negative regulation of organelle organization GO:0010639 56 0.010
nucleotide metabolic process GO:0009117 161 0.010
negative regulation of cell cycle GO:0045786 116 0.010
leg disc development GO:0035218 92 0.010
tube development GO:0035295 244 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
chondroitin sulfate proteoglycan biosynthetic process GO:0050650 3 0.010
regulation of defense response to bacterium GO:1900424 30 0.010
regulation of proteolysis GO:0030162 87 0.010
establishment of rna localization GO:0051236 47 0.010
axon midline choice point recognition GO:0016199 26 0.010
carbohydrate derivative metabolic process GO:1901135 217 0.010
regulation of response to wounding GO:1903034 19 0.010

fax disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.014
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010