Drosophila melanogaster

215 known processes

Parp (Dmel_CG40411)

Poly-(ADP-ribose) polymerase

(Aliases: Dmel\CG40411,PARP-1,CG17718,D.PARP,LD21673.3prime,PARP1,CG17696,dPARP,CG17685,PARP,BEST:LD21673,CG40411)

Parp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.718
negative regulation of cellular metabolic process GO:0031324 382 0.655
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.637
chromatin silencing GO:0006342 76 0.616
defense response GO:0006952 300 0.596
regulation of gene expression epigenetic GO:0040029 128 0.537
negative regulation of rna metabolic process GO:0051253 251 0.525
compound eye morphogenesis GO:0001745 249 0.517
columnar cuboidal epithelial cell development GO:0002066 249 0.511
eye development GO:0001654 323 0.496
sensory organ morphogenesis GO:0090596 260 0.431
compound eye development GO:0048749 307 0.398
myoblast fusion GO:0007520 43 0.387
negative regulation of gene expression epigenetic GO:0045814 77 0.378
morphogenesis of a polarized epithelium GO:0001738 93 0.375
chromatin organization GO:0006325 207 0.367
gene silencing GO:0016458 138 0.362
negative regulation of developmental process GO:0051093 201 0.339
response to biotic stimulus GO:0009607 294 0.337
growth GO:0040007 359 0.337
Mouse
eye morphogenesis GO:0048592 260 0.335
negative regulation of gene expression GO:0010629 387 0.332
innate immune response GO:0045087 144 0.310
female meiotic division GO:0007143 70 0.302
morphogenesis of an epithelium GO:0002009 276 0.289
immune response GO:0006955 246 0.287
establishment of planar polarity GO:0001736 87 0.279
embryo development ending in birth or egg hatching GO:0009792 152 0.270
negative regulation of biosynthetic process GO:0009890 277 0.266
ovarian follicle cell development GO:0030707 248 0.258
imaginal disc derived appendage development GO:0048737 399 0.256
negative regulation of rna biosynthetic process GO:1902679 240 0.249
positive regulation of autophagy GO:0010508 21 0.241
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.238
response to external biotic stimulus GO:0043207 293 0.236
defense response to bacterium GO:0042742 178 0.235
negative regulation of cellular biosynthetic process GO:0031327 277 0.226
developmental programmed cell death GO:0010623 138 0.225
response to temperature stimulus GO:0009266 106 0.218
establishment of tissue polarity GO:0007164 87 0.217
nucleus organization GO:0006997 45 0.214
dorsal appendage formation GO:0046843 47 0.210
response to other organism GO:0051707 293 0.210
regulation of growth GO:0040008 233 0.205
Mouse
negative regulation of transcription dna templated GO:0045892 237 0.204
chromosome organization GO:0051276 360 0.200
compound eye cone cell differentiation GO:0042675 13 0.195
response to bacterium GO:0009617 198 0.194
nuclear division GO:0000280 332 0.193
tissue morphogenesis GO:0048729 297 0.185
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.182
digestive tract development GO:0048565 149 0.178
autophagy GO:0006914 108 0.176
appendage development GO:0048736 401 0.175
regulation of protein metabolic process GO:0051246 256 0.174
appendage morphogenesis GO:0035107 397 0.165
immune effector process GO:0002252 98 0.162
developmental pigmentation GO:0048066 68 0.161
immune system process GO:0002376 347 0.160
negative regulation of nucleic acid templated transcription GO:1903507 240 0.159
digestive system development GO:0055123 149 0.155
protein localization to nucleus GO:0034504 55 0.154
regulation of proteolysis GO:0030162 87 0.154
dorsal closure GO:0007391 79 0.149
syncytium formation GO:0006949 43 0.148
regulation of mitotic cell cycle phase transition GO:1901990 130 0.147
tube morphogenesis GO:0035239 191 0.147
chromosome segregation GO:0007059 157 0.136
regulation of immune response GO:0050776 118 0.135
meiotic chromosome segregation GO:0045132 59 0.131
regulation of autophagy GO:0010506 62 0.129
imaginal disc derived wing morphogenesis GO:0007476 337 0.127
establishment of ommatidial planar polarity GO:0042067 49 0.123
epithelial cell development GO:0002064 274 0.118
ovarian follicle cell migration GO:0007297 121 0.118
regulation of cellular protein metabolic process GO:0032268 243 0.116
negative regulation of cell differentiation GO:0045596 143 0.116
regulation of cell differentiation GO:0045595 302 0.115
positive regulation of macromolecule metabolic process GO:0010604 405 0.113
organic substance catabolic process GO:1901575 308 0.113
establishment of localization in cell GO:0051649 402 0.111
regulation of chromosome organization GO:0033044 64 0.110
inter male aggressive behavior GO:0002121 60 0.104
nuclear body organization GO:0030575 6 0.104
positive regulation of biosynthetic process GO:0009891 316 0.103
telomere organization GO:0032200 21 0.103
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.102
defense response to other organism GO:0098542 225 0.101
regionalization GO:0003002 416 0.100
muscle organ development GO:0007517 127 0.098
regulation of anatomical structure morphogenesis GO:0022603 242 0.098
regulation of cell cycle phase transition GO:1901987 130 0.096
post embryonic appendage morphogenesis GO:0035120 385 0.094
embryonic development via the syncytial blastoderm GO:0001700 148 0.093
organelle fission GO:0048285 340 0.092
regulation of organelle organization GO:0033043 196 0.091
intracellular signal transduction GO:0035556 300 0.090
epithelial cell differentiation GO:0030855 322 0.089
regulation of dna metabolic process GO:0051052 34 0.088
dna damage checkpoint GO:0000077 78 0.086
eggshell formation GO:0030703 105 0.086
response to heat GO:0009408 63 0.084
myotube differentiation GO:0014902 46 0.084
embryonic morphogenesis GO:0048598 206 0.083
proteolysis GO:0006508 192 0.082
cellular catabolic process GO:0044248 372 0.082
regulation of defense response GO:0031347 102 0.080
regulation of establishment of planar polarity GO:0090175 22 0.079
organonitrogen compound metabolic process GO:1901564 318 0.077
eggshell chorion assembly GO:0007306 66 0.075
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.075
programmed cell death GO:0012501 257 0.075
syncytium formation by plasma membrane fusion GO:0000768 43 0.075
cellular response to heat GO:0034605 24 0.073
chorion containing eggshell formation GO:0007304 105 0.073
catabolic process GO:0009056 409 0.072
developmental growth GO:0048589 280 0.072
response to organic substance GO:0010033 284 0.072
photoreceptor cell differentiation GO:0046530 170 0.070
jnk cascade GO:0007254 50 0.066
death GO:0016265 284 0.065
regulation of cell development GO:0060284 215 0.064
gland development GO:0048732 191 0.063
regulation of response to oxidative stress GO:1902882 4 0.063
regulation of organ morphogenesis GO:2000027 78 0.061
head development GO:0060322 135 0.060
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.060
aggressive behavior GO:0002118 63 0.059
morphogenesis of embryonic epithelium GO:0016331 94 0.059
determination of adult lifespan GO:0008340 137 0.058
germarium derived egg chamber formation GO:0007293 101 0.057
photoreceptor cell development GO:0042461 96 0.056
muscle cell differentiation GO:0042692 103 0.056
chromosome separation GO:0051304 42 0.056
phosphorylation GO:0016310 294 0.055
stem cell differentiation GO:0048863 117 0.054
regulation of epithelial cell differentiation GO:0030856 4 0.054
negative regulation of cell fate specification GO:0009996 15 0.054
response to oxygen containing compound GO:1901700 200 0.054
Mouse
regulation of cellular catabolic process GO:0031329 157 0.052
regulation of catabolic process GO:0009894 170 0.052
chromatin assembly GO:0031497 48 0.051
tissue death GO:0016271 102 0.051
macroautophagy GO:0016236 42 0.051
macromolecule catabolic process GO:0009057 161 0.051
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.050
apoptotic process GO:0006915 159 0.050
regulation of cellular component biogenesis GO:0044087 201 0.049
regulation of endopeptidase activity GO:0052548 36 0.049
meiotic cell cycle process GO:1903046 132 0.049
epithelial cell migration GO:0010631 148 0.048
molting cycle chitin based cuticle GO:0007591 56 0.048
compound eye retinal cell programmed cell death GO:0046667 23 0.047
adult chitin based cuticle development GO:0008365 2 0.047
anatomical structure homeostasis GO:0060249 97 0.047
Mouse
positive regulation of programmed cell death GO:0043068 62 0.046
cellular macromolecule catabolic process GO:0044265 136 0.046
regulation of immune system process GO:0002682 176 0.046
positive regulation of response to stimulus GO:0048584 323 0.046
dna metabolic process GO:0006259 227 0.045
Mouse
negative regulation of photoreceptor cell differentiation GO:0046533 8 0.045
single organism catabolic process GO:0044712 228 0.044
cuticle development GO:0042335 86 0.044
aging GO:0007568 143 0.043
ommatidial rotation GO:0016318 20 0.043
regulation of cellular response to stress GO:0080135 89 0.043
positive regulation of protein metabolic process GO:0051247 128 0.043
cell proliferation GO:0008283 299 0.042
cell growth GO:0016049 108 0.042
regulation of innate immune response GO:0045088 71 0.041
central nervous system development GO:0007417 201 0.040
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.040
regulation of chromatin organization GO:1902275 32 0.040
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.040
cytoplasmic transport GO:0016482 130 0.040
regulation of peptidase activity GO:0052547 39 0.040
modification dependent macromolecule catabolic process GO:0043632 79 0.040
cell cycle checkpoint GO:0000075 95 0.040
multicellular organismal aging GO:0010259 140 0.040
meiotic cell cycle GO:0051321 171 0.040
positive regulation of organelle organization GO:0010638 65 0.039
meiotic nuclear division GO:0007126 151 0.039
histolysis GO:0007559 102 0.039
defense response to gram negative bacterium GO:0050829 94 0.039
cellular ketone metabolic process GO:0042180 24 0.038
camera type eye morphogenesis GO:0048593 2 0.038
stress activated mapk cascade GO:0051403 52 0.038
wing disc morphogenesis GO:0007472 344 0.038
circadian rhythm GO:0007623 105 0.037
compound eye photoreceptor fate commitment GO:0001752 36 0.037
cell death GO:0008219 279 0.037
ubiquitin dependent protein catabolic process GO:0006511 78 0.037
regulation of multicellular organismal development GO:2000026 414 0.036
regulation of photoreceptor cell differentiation GO:0046532 34 0.036
behavioral response to ethanol GO:0048149 49 0.036
regulation of developmental growth GO:0048638 174 0.036
brain development GO:0007420 120 0.035
regulation of catalytic activity GO:0050790 185 0.035
regulation of neurogenesis GO:0050767 158 0.035
negative regulation of cell cycle GO:0045786 116 0.035
modification dependent protein catabolic process GO:0019941 78 0.035
cellular protein catabolic process GO:0044257 83 0.035
positive regulation of cell size GO:0045793 21 0.035
striated muscle cell differentiation GO:0051146 90 0.034
mapk cascade GO:0000165 107 0.033
negative regulation of cell communication GO:0010648 223 0.033
phagocytosis GO:0006909 215 0.033
multi organism behavior GO:0051705 175 0.033
visceral muscle development GO:0007522 14 0.033
positive regulation of proteolysis GO:0045862 52 0.033
positive regulation of cellular component organization GO:0051130 156 0.032
biological adhesion GO:0022610 138 0.032
cell cycle phase transition GO:0044770 140 0.031
mitotic spindle organization GO:0007052 220 0.031
small molecule metabolic process GO:0044281 305 0.031
camera type eye development GO:0043010 4 0.031
regulation of response to stress GO:0080134 200 0.031
regulation of apoptotic process GO:0042981 130 0.030
negative regulation of multicellular organismal process GO:0051241 142 0.030
positive regulation of immune response GO:0050778 63 0.030
endocytosis GO:0006897 310 0.029
macromolecular complex assembly GO:0065003 256 0.029
regulation of cellular amine metabolic process GO:0033238 3 0.029
positive regulation of endopeptidase activity GO:0010950 26 0.029
lateral inhibition GO:0046331 206 0.028
hindbrain development GO:0030902 2 0.028
response to extracellular stimulus GO:0009991 116 0.028
autophagic cell death GO:0048102 83 0.028
negative regulation of molecular function GO:0044092 51 0.028
lipid localization GO:0010876 54 0.028
imaginal disc derived wing hair organization GO:0035317 45 0.028
regulation of programmed cell death GO:0043067 152 0.028
regulation of nervous system development GO:0051960 248 0.028
dna replication GO:0006260 48 0.028
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.027
regulation of phosphorylation GO:0042325 147 0.027
imaginal disc derived appendage morphogenesis GO:0035114 395 0.027
positive regulation of cellular protein metabolic process GO:0032270 118 0.027
regulation of anatomical structure size GO:0090066 163 0.027
regulation of cellular response to oxidative stress GO:1900407 4 0.026
retinal cell programmed cell death GO:0046666 25 0.026
cellular response to peptide GO:1901653 28 0.026
regulation of neuron differentiation GO:0045664 103 0.026
negative regulation of growth GO:0045926 84 0.026
establishment or maintenance of cell polarity GO:0007163 167 0.026
response to wounding GO:0009611 94 0.026
regulation of developmental pigmentation GO:0048070 24 0.026
regulation of phosphate metabolic process GO:0019220 210 0.026
protein maturation GO:0051604 71 0.025
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.025
border follicle cell migration GO:0007298 113 0.025
nucleocytoplasmic transport GO:0006913 72 0.025
regulation of mapk cascade GO:0043408 92 0.025
regulation of epidermal cell differentiation GO:0045604 3 0.025
regulation of immune effector process GO:0002697 52 0.025
regulation of stress activated mapk cascade GO:0032872 41 0.024
epidermal growth factor receptor signaling pathway GO:0007173 58 0.024
translation GO:0006412 69 0.024
adult chitin containing cuticle pigmentation GO:0048085 16 0.024
positive regulation of catalytic activity GO:0043085 118 0.024
purine nucleoside metabolic process GO:0042278 127 0.024
retina development in camera type eye GO:0060041 4 0.024
innate immune response activating signal transduction GO:0002758 2 0.024
muscle structure development GO:0061061 224 0.024
positive regulation of gene expression GO:0010628 290 0.024
posttranscriptional regulation of gene expression GO:0010608 145 0.024
epithelium migration GO:0090132 148 0.023
exocrine system development GO:0035272 162 0.023
immune response activating signal transduction GO:0002757 2 0.023
pigmentation GO:0043473 75 0.023
wound healing GO:0042060 75 0.023
response to nutrient levels GO:0031667 114 0.023
positive regulation of cellular catabolic process GO:0031331 95 0.022
open tracheal system development GO:0007424 204 0.022
protein modification process GO:0036211 438 0.022
regulation of antimicrobial humoral response GO:0002759 50 0.022
cell aging GO:0007569 2 0.022
positive regulation of signaling GO:0023056 243 0.022
dna integrity checkpoint GO:0031570 81 0.022
nuclear transport GO:0051169 72 0.022
positive regulation of catabolic process GO:0009896 105 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.022
regulation of chromatin modification GO:1903308 28 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
chitin based cuticle development GO:0040003 49 0.021
female meiosis chromosome segregation GO:0016321 33 0.021
regulation of circadian rhythm GO:0042752 49 0.021
protein localization GO:0008104 284 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
negative regulation of cellular protein metabolic process GO:0032269 85 0.020
regulation of multi organism process GO:0043900 131 0.020
regulation of cellular component size GO:0032535 98 0.020
lipid metabolic process GO:0006629 121 0.020
regulation of jnk cascade GO:0046328 40 0.020
nuclear import GO:0051170 51 0.020
regulation of phosphatase activity GO:0010921 3 0.020
protein catabolic process GO:0030163 101 0.020
response to lipopolysaccharide GO:0032496 4 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.020
regulation of cuticle pigmentation GO:0048079 16 0.020
salivary gland cell autophagic cell death GO:0035071 83 0.020
mitotic sister chromatid segregation GO:0000070 87 0.020
regulation of notch signaling pathway GO:0008593 100 0.020
amine metabolic process GO:0009308 12 0.019
regulation of cell cycle GO:0051726 291 0.019
chromatin remodeling GO:0006338 72 0.019
negative regulation of cell development GO:0010721 62 0.019
forebrain development GO:0030900 2 0.019
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.019
retina morphogenesis in camera type eye GO:0060042 2 0.019
cellular response to biotic stimulus GO:0071216 4 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.018
positive regulation of r7 cell differentiation GO:0045678 7 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
positive regulation of cellular component biogenesis GO:0044089 80 0.018
regulation of translation GO:0006417 56 0.018
organic hydroxy compound metabolic process GO:1901615 83 0.018
fusion cell fate specification GO:0035156 4 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.018
non sensory hair organization GO:0035316 47 0.018
negative regulation of developmental growth GO:0048640 64 0.017
regulation of dna replication GO:0006275 13 0.017
regulation of organ growth GO:0046620 42 0.017
homeostatic process GO:0042592 199 0.017
Mouse
cellular lipid metabolic process GO:0044255 83 0.017
response to organonitrogen compound GO:0010243 75 0.017
response to endogenous stimulus GO:0009719 119 0.017
regulation of defense response to virus GO:0050688 14 0.017
establishment of protein localization GO:0045184 163 0.017
skin development GO:0043588 65 0.017
digestive tract morphogenesis GO:0048546 127 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
negative regulation of apoptotic process GO:0043066 63 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.016
single organism intracellular transport GO:1902582 207 0.016
intracellular protein transport GO:0006886 104 0.016
regulation of nucleocytoplasmic transport GO:0046822 35 0.016
regulation of gene silencing GO:0060968 63 0.016
developmental maturation GO:0021700 172 0.016
regulation of mrna processing GO:0050684 71 0.016
regulation of syncytium formation by plasma membrane fusion GO:0060142 6 0.016
cellular response to oxygen containing compound GO:1901701 79 0.016
Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
regulation of chromatin silencing GO:0031935 36 0.016
vesicle mediated transport GO:0016192 381 0.016
cellular component assembly involved in morphogenesis GO:0010927 151 0.016
salivary gland morphogenesis GO:0007435 145 0.016
spermatogenesis GO:0007283 200 0.016
protein import GO:0017038 55 0.016
regulation of cell size GO:0008361 63 0.016
oxoacid metabolic process GO:0043436 103 0.016
skeletal muscle fiber development GO:0048741 3 0.016
stress activated protein kinase signaling cascade GO:0031098 55 0.016
cognition GO:0050890 141 0.016
mitotic sister chromatid separation GO:0051306 30 0.015
genital disc development GO:0035215 44 0.015
protein complex biogenesis GO:0070271 201 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
Mouse
protein phosphorylation GO:0006468 169 0.015
regulation of macroautophagy GO:0016241 15 0.015
positive regulation of molecular function GO:0044093 136 0.015
negative regulation of mitotic cell cycle GO:0045930 109 0.015
ameboidal type cell migration GO:0001667 151 0.015
notch signaling pathway GO:0007219 120 0.015
negative regulation of neurogenesis GO:0050768 53 0.015
response to ecdysone GO:0035075 34 0.015
negative regulation of signal transduction GO:0009968 206 0.015
regulation of heterochromatin assembly GO:0031445 8 0.015
compound eye photoreceptor cell differentiation GO:0001751 140 0.015
single organism biosynthetic process GO:0044711 206 0.015
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.015
rna 3 end processing GO:0031123 45 0.015
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.015
eye photoreceptor cell fate commitment GO:0042706 37 0.015
stem cell maintenance GO:0019827 67 0.015
synaptic transmission GO:0007268 288 0.015
metaphase anaphase transition of cell cycle GO:0044784 28 0.014
protein processing GO:0016485 68 0.014
chromatin assembly or disassembly GO:0006333 52 0.014
intracellular transport GO:0046907 228 0.014
regulation of cell morphogenesis GO:0022604 163 0.014
regulation of mitotic sister chromatid separation GO:0010965 28 0.014
positive regulation of epithelial cell differentiation GO:0030858 1 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.014
antimicrobial humoral response GO:0019730 99 0.014
salivary gland histolysis GO:0035070 88 0.014
pattern recognition receptor signaling pathway GO:0002221 2 0.014
compound eye cone cell fate commitment GO:0042676 5 0.014
cellular protein localization GO:0034613 160 0.014
heterocycle catabolic process GO:0046700 166 0.014
regulation of chitin based cuticle tanning GO:0007564 14 0.014
negative regulation of nervous system development GO:0051961 92 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
positive regulation of hydrolase activity GO:0051345 78 0.013
response to abiotic stimulus GO:0009628 341 0.013
myotube cell development GO:0014904 3 0.013
cellular protein modification process GO:0006464 438 0.013
male gamete generation GO:0048232 201 0.013
positive regulation of immune system process GO:0002684 68 0.013
positive regulation of peptidase activity GO:0010952 29 0.013
striated muscle cell development GO:0055002 50 0.013
protein complex assembly GO:0006461 200 0.013
regulation of execution phase of apoptosis GO:1900117 5 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.013
chromatin modification GO:0016568 147 0.013
response to starvation GO:0042594 97 0.013
protein import into nucleus GO:0006606 51 0.013
positive regulation of cell death GO:0010942 69 0.013
humoral immune response GO:0006959 117 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
regulation of response to external stimulus GO:0032101 115 0.013
detection of external biotic stimulus GO:0098581 2 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.013
erbb signaling pathway GO:0038127 58 0.012
mitotic dna integrity checkpoint GO:0044774 75 0.012
single organism cellular localization GO:1902580 180 0.012
response to fungus GO:0009620 50 0.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.012
regulation of proteasomal protein catabolic process GO:0061136 39 0.012
spermatid development GO:0007286 98 0.012
positive regulation of retinal cell programmed cell death GO:0046670 9 0.012
regulation of multicellular organism growth GO:0040014 40 0.012
negative regulation of catabolic process GO:0009895 36 0.012
positive regulation of response to extracellular stimulus GO:0032106 8 0.012
nephrocyte diaphragm assembly GO:0036059 3 0.012
regulation of response to nutrient levels GO:0032107 18 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
regulation of embryonic development GO:0045995 68 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.012
cellular response to peptide hormone stimulus GO:0071375 28 0.012
adult behavior GO:0030534 137 0.012
organic acid metabolic process GO:0006082 103 0.012
mitotic cell cycle phase transition GO:0044772 138 0.011
rna processing GO:0006396 147 0.011
cellular macromolecule localization GO:0070727 220 0.011
respiratory system development GO:0060541 213 0.011
protein targeting GO:0006605 64 0.011
cell maturation GO:0048469 144 0.011
regulation of erbb signaling pathway GO:1901184 42 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
regulation of cell death GO:0010941 173 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.011
negative regulation of protein processing GO:0010955 31 0.011
cellular response to nutrient levels GO:0031669 62 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
signal transduction in response to dna damage GO:0042770 3 0.011
paracrine signaling GO:0038001 7 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
regulation of chromosome segregation GO:0051983 32 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
cellular response to extracellular stimulus GO:0031668 64 0.011
ras protein signal transduction GO:0007265 88 0.011
regulation of retinal cell programmed cell death GO:0046668 18 0.011
anion transport GO:0006820 41 0.010
cuticle pattern formation GO:0035017 27 0.010
cell motility GO:0048870 251 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
dna conformation change GO:0071103 105 0.010
negative regulation of cell cycle process GO:0010948 109 0.010
carbohydrate metabolic process GO:0005975 82 0.010
response to sterol GO:0036314 34 0.010
negative regulation of cell cycle phase transition GO:1901988 103 0.010
micropyle formation GO:0046844 4 0.010
cellular response to starvation GO:0009267 61 0.010
negative regulation of immune system process GO:0002683 50 0.010
positive regulation of defense response GO:0031349 59 0.010
regulation of lipid transport GO:0032368 3 0.010
generation of precursor metabolites and energy GO:0006091 42 0.010
negative regulation of programmed cell death GO:0043069 72 0.010
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.010

Parp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016