Drosophila melanogaster

36 known processes

dmt (Dmel_CG8374)

dalmatian

(Aliases: Dmel\CG8374,0481/03,anon-WO0118547.317,Dmt,CG8374,s048103)

dmt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of rna metabolic process GO:0051254 271 0.508
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.504
mrna metabolic process GO:0016071 124 0.416
regulation of mitotic cell cycle GO:0007346 190 0.408
regulation of cell cycle phase transition GO:1901987 130 0.407
single organism intracellular transport GO:1902582 207 0.300
mitotic cell cycle phase transition GO:0044772 138 0.291
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.261
regulation of cell cycle process GO:0010564 181 0.236
endocytosis GO:0006897 310 0.230
double strand break repair via homologous recombination GO:0000724 13 0.204
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.182
chromatin modification GO:0016568 147 0.181
regulation of mitotic cell cycle phase transition GO:1901990 130 0.170
cellular macromolecule localization GO:0070727 220 0.167
negative regulation of rna biosynthetic process GO:1902679 240 0.160
positive regulation of macromolecule metabolic process GO:0010604 405 0.156
regulation of dna metabolic process GO:0051052 34 0.152
negative regulation of cell cycle phase transition GO:1901988 103 0.145
negative regulation of cell cycle GO:0045786 116 0.144
regulation of cell cycle GO:0051726 291 0.141
negative regulation of transcription dna templated GO:0045892 237 0.139
muscle structure development GO:0061061 224 0.133
organic substance transport GO:0071702 257 0.128
cell cycle checkpoint GO:0000075 95 0.127
negative regulation of biosynthetic process GO:0009890 277 0.127
positive regulation of peptidase activity GO:0010952 29 0.121
response to organic cyclic compound GO:0014070 89 0.115
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.114
camera type eye development GO:0043010 4 0.114
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.110
transcription from rna polymerase ii promoter GO:0006366 368 0.109
stem cell differentiation GO:0048863 117 0.108
regulation of cellular localization GO:0060341 136 0.104
dna damage checkpoint GO:0000077 78 0.101
vesicle mediated transport GO:0016192 381 0.092
mrna processing GO:0006397 104 0.090
response to organic substance GO:0010033 284 0.090
negative regulation of cell cycle process GO:0010948 109 0.090
ameboidal type cell migration GO:0001667 151 0.089
negative regulation of gene expression GO:0010629 387 0.088
cellular macromolecular complex assembly GO:0034622 153 0.087
tissue morphogenesis GO:0048729 297 0.087
homeostatic process GO:0042592 199 0.085
regulation of protein transport GO:0051223 57 0.083
dna repair GO:0006281 54 0.082
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.081
negative regulation of mitotic cell cycle GO:0045930 109 0.080
regulation of dna repair GO:0006282 5 0.078
negative regulation of cell proliferation GO:0008285 69 0.076
regulation of hydrolase activity GO:0051336 97 0.075
ribonucleoside triphosphate metabolic process GO:0009199 119 0.074
protein targeting to nucleus GO:0044744 51 0.072
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.071
positive regulation of gene expression GO:0010628 290 0.071
rna splicing via transesterification reactions GO:0000375 73 0.070
mitotic sister chromatid segregation GO:0000070 87 0.069
negative regulation of cellular metabolic process GO:0031324 382 0.068
cellular response to dna damage stimulus GO:0006974 223 0.068
negative regulation of rna metabolic process GO:0051253 251 0.068
regulation of protein localization GO:0032880 76 0.067
positive regulation of endopeptidase activity GO:0010950 26 0.067
establishment of protein localization GO:0045184 163 0.066
regulation of intracellular protein transport GO:0033157 46 0.066
stem cell development GO:0048864 79 0.066
negative regulation of cellular biosynthetic process GO:0031327 277 0.065
cell fate specification GO:0001708 71 0.065
negative regulation of cell differentiation GO:0045596 143 0.064
cellular homeostasis GO:0019725 80 0.064
regulation of cytoplasmic transport GO:1903649 47 0.063
regulation of dna recombination GO:0000018 4 0.062
positive regulation of response to stimulus GO:0048584 323 0.062
retina development in camera type eye GO:0060041 4 0.062
phagocytosis GO:0006909 215 0.060
sister chromatid segregation GO:0000819 92 0.059
positive regulation of molecular function GO:0044093 136 0.059
positive regulation of transcription dna templated GO:0045893 266 0.058
morphogenesis of an epithelium GO:0002009 276 0.057
dna replication GO:0006260 48 0.056
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.056
transmembrane transport GO:0055085 139 0.056
epithelial tube morphogenesis GO:0060562 88 0.056
single organism membrane organization GO:0044802 93 0.056
localization of cell GO:0051674 257 0.055
regulation of establishment of protein localization GO:0070201 61 0.055
cellular protein localization GO:0034613 160 0.055
regulation of cellular protein metabolic process GO:0032268 243 0.054
small molecule metabolic process GO:0044281 305 0.054
response to reactive oxygen species GO:0000302 24 0.052
cellular response to organic substance GO:0071310 132 0.052
regulation of intracellular transport GO:0032386 64 0.051
chromatin remodeling GO:0006338 72 0.051
organelle fission GO:0048285 340 0.050
cell fate determination GO:0001709 91 0.050
protein transport GO:0015031 155 0.049
negative regulation of cellular protein metabolic process GO:0032269 85 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.049
aging GO:0007568 143 0.048
appendage development GO:0048736 401 0.048
recombinational repair GO:0000725 13 0.047
positive regulation of proteolysis GO:0045862 52 0.047
death GO:0016265 284 0.047
regulation of cell proliferation GO:0042127 163 0.047
regulation of gene silencing GO:0060968 63 0.046
regulation of phosphorus metabolic process GO:0051174 210 0.046
positive regulation of hydrolase activity GO:0051345 78 0.045
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.044
positive regulation of protein metabolic process GO:0051247 128 0.044
immune response GO:0006955 246 0.044
epithelial cell migration GO:0010631 148 0.044
intracellular protein transport GO:0006886 104 0.043
cellular response to chemical stimulus GO:0070887 199 0.043
cell cycle phase transition GO:0044770 140 0.043
negative regulation of response to stimulus GO:0048585 258 0.042
positive regulation of protein transport GO:0051222 37 0.042
purine nucleotide metabolic process GO:0006163 146 0.041
translesion synthesis GO:0019985 2 0.040
establishment of localization in cell GO:0051649 402 0.038
regulation of protein metabolic process GO:0051246 256 0.038
striated muscle cell development GO:0055002 50 0.038
single organism cellular localization GO:1902580 180 0.037
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.037
regulation of phosphate metabolic process GO:0019220 210 0.037
cell motility GO:0048870 251 0.037
rna processing GO:0006396 147 0.037
regulation of organelle organization GO:0033043 196 0.037
ribonucleoside catabolic process GO:0042454 112 0.037
response to oxygen containing compound GO:1901700 200 0.035
response to lipopolysaccharide GO:0032496 4 0.035
divalent inorganic cation homeostasis GO:0072507 29 0.035
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.034
heart process GO:0003015 37 0.034
protein localization to organelle GO:0033365 82 0.034
single organism nuclear import GO:1902593 51 0.034
postreplication repair GO:0006301 2 0.034
regulation of cell death GO:0010941 173 0.034
cell death GO:0008219 279 0.033
negative regulation of developmental process GO:0051093 201 0.033
protein phosphorylation GO:0006468 169 0.033
nuclear import GO:0051170 51 0.032
glycosyl compound metabolic process GO:1901657 127 0.031
response to nitrogen compound GO:1901698 90 0.031
divalent metal ion transport GO:0070838 26 0.031
response to other organism GO:0051707 293 0.031
negative regulation of protein metabolic process GO:0051248 85 0.031
purine ribonucleoside metabolic process GO:0046128 127 0.030
positive regulation of cell migration GO:0030335 2 0.029
regulation of localization GO:0032879 275 0.029
regulation of molecular function GO:0065009 217 0.029
growth GO:0040007 359 0.029
dna metabolic process GO:0006259 227 0.029
posttranscriptional regulation of gene expression GO:0010608 145 0.029
regulation of protein localization to nucleus GO:1900180 29 0.029
response to alcohol GO:0097305 95 0.028
eye development GO:0001654 323 0.028
protein targeting GO:0006605 64 0.028
stem cell maintenance GO:0019827 67 0.028
cellular protein complex assembly GO:0043623 71 0.027
positive regulation of transport GO:0051050 92 0.027
positive regulation of apoptotic process GO:0043065 47 0.027
positive regulation of cellular biosynthetic process GO:0031328 316 0.027
hindgut morphogenesis GO:0007442 58 0.027
ribonucleoside monophosphate metabolic process GO:0009161 51 0.027
nucleoside metabolic process GO:0009116 127 0.026
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.026
regulation of sequestering of calcium ion GO:0051282 3 0.026
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.025
atp catabolic process GO:0006200 38 0.025
regulation of cytoskeleton organization GO:0051493 89 0.025
blood circulation GO:0008015 26 0.025
cell migration GO:0016477 238 0.025
negative regulation of nucleic acid templated transcription GO:1903507 240 0.025
cellular cation homeostasis GO:0030003 38 0.025
actomyosin structure organization GO:0031032 56 0.025
nucleobase containing compound catabolic process GO:0034655 165 0.025
purine nucleoside triphosphate metabolic process GO:0009144 119 0.025
single organism biosynthetic process GO:0044711 206 0.024
dendrite morphogenesis GO:0048813 199 0.024
taxis GO:0042330 304 0.024
mrna splicing via spliceosome GO:0000398 73 0.024
protein localization GO:0008104 284 0.024
spindle organization GO:0007051 253 0.024
double strand break repair GO:0006302 26 0.024
response to endogenous stimulus GO:0009719 119 0.024
ribonucleoprotein complex subunit organization GO:0071826 28 0.024
negative regulation of dna metabolic process GO:0051053 12 0.024
developmental growth GO:0048589 280 0.024
positive regulation of mitotic cell cycle GO:0045931 34 0.024
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
arp2 3 complex mediated actin nucleation GO:0034314 3 0.023
response to organonitrogen compound GO:0010243 75 0.023
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.023
positive regulation of cellular protein metabolic process GO:0032270 118 0.023
ion transport GO:0006811 145 0.022
regulation of peptidase activity GO:0052547 39 0.022
actin cytoskeleton organization GO:0030036 206 0.022
regulation of mrna metabolic process GO:1903311 72 0.022
embryo development ending in birth or egg hatching GO:0009792 152 0.022
protein modification by small protein conjugation GO:0032446 79 0.022
intracellular signal transduction GO:0035556 300 0.022
carbohydrate derivative catabolic process GO:1901136 118 0.022
regulation of embryonic development GO:0045995 68 0.021
protein polymerization GO:0051258 42 0.021
carboxylic acid metabolic process GO:0019752 92 0.021
positive regulation of signaling GO:0023056 243 0.021
positive regulation of organelle organization GO:0010638 65 0.021
positive regulation of protein modification process GO:0031401 58 0.021
regulation of catalytic activity GO:0050790 185 0.021
regulation of mrna splicing via spliceosome GO:0048024 64 0.021
positive regulation of cellular component organization GO:0051130 156 0.021
aromatic compound catabolic process GO:0019439 166 0.020
regulation of catabolic process GO:0009894 170 0.020
nucleobase containing small molecule metabolic process GO:0055086 174 0.020
regulation of nuclear division GO:0051783 58 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
cellular chemical homeostasis GO:0055082 40 0.020
regulation of blood circulation GO:1903522 21 0.020
tube development GO:0035295 244 0.020
protein import into nucleus GO:0006606 51 0.020
membrane organization GO:0061024 112 0.020
negative regulation of organelle organization GO:0010639 56 0.020
chromatin mediated maintenance of transcription GO:0048096 7 0.019
protein modification process GO:0036211 438 0.019
cellular response to organic cyclic compound GO:0071407 32 0.019
positive regulation of cell cycle GO:0045787 43 0.019
chromatin organization GO:0006325 207 0.019
regulation of cell migration GO:0030334 22 0.019
protein complex assembly GO:0006461 200 0.019
positive regulation of intracellular transport GO:0032388 42 0.019
metaphase anaphase transition of cell cycle GO:0044784 28 0.018
g1 s transition of mitotic cell cycle GO:0000082 31 0.018
macromolecule methylation GO:0043414 45 0.018
heterocycle catabolic process GO:0046700 166 0.018
innate immune response GO:0045087 144 0.018
maintenance of location GO:0051235 73 0.018
mitotic recombination GO:0006312 2 0.018
protein complex biogenesis GO:0070271 201 0.018
positive regulation of signal transduction GO:0009967 223 0.017
rna splicing GO:0008380 83 0.017
regulation of rna splicing GO:0043484 69 0.017
larval development GO:0002164 104 0.017
immune system process GO:0002376 347 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.017
catabolic process GO:0009056 409 0.017
axon development GO:0061564 297 0.017
regulation of protein complex assembly GO:0043254 42 0.017
negative regulation of gene expression epigenetic GO:0045814 77 0.017
regulation of transport GO:0051049 181 0.016
alternative mrna splicing via spliceosome GO:0000380 60 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
regulation of epithelial cell proliferation GO:0050678 4 0.016
cellular response to oxygen containing compound GO:1901701 79 0.016
atp metabolic process GO:0046034 49 0.016
appendage morphogenesis GO:0035107 397 0.016
ribonucleoprotein complex assembly GO:0022618 23 0.016
positive regulation of cytoskeleton organization GO:0051495 21 0.016
amine metabolic process GO:0009308 12 0.016
genital disc development GO:0035215 44 0.016
cell division GO:0051301 248 0.016
cellular response to endogenous stimulus GO:0071495 80 0.016
hindgut development GO:0061525 58 0.015
response to external biotic stimulus GO:0043207 293 0.015
glial cell differentiation GO:0010001 35 0.015
regulation of meiosis GO:0040020 3 0.015
cell proliferation GO:0008283 299 0.015
macromolecular complex assembly GO:0065003 256 0.015
body morphogenesis GO:0010171 2 0.015
negative regulation of phosphate metabolic process GO:0045936 45 0.015
protein import GO:0017038 55 0.015
cellular ion homeostasis GO:0006873 39 0.015
negative regulation of cellular component organization GO:0051129 108 0.015
chromosome organization GO:0051276 360 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
nuclear division GO:0000280 332 0.014
embryonic morphogenesis GO:0048598 206 0.014
response to oxidative stress GO:0006979 86 0.014
imaginal disc derived appendage development GO:0048737 399 0.014
histone modification GO:0016570 106 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
epithelium migration GO:0090132 148 0.014
regulation of chromatin modification GO:1903308 28 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
regulation of chromosome organization GO:0033044 64 0.014
organelle assembly GO:0070925 198 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
negative regulation of epithelial cell proliferation GO:0050680 4 0.014
anatomical structure homeostasis GO:0060249 97 0.014
nucleotide metabolic process GO:0009117 161 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
immune effector process GO:0002252 98 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
plasma membrane organization GO:0007009 26 0.013
dna double strand break processing GO:0000729 3 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
cation transport GO:0006812 110 0.013
mitotic sister chromatid separation GO:0051306 30 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
regulation of protein import into nucleus GO:0042306 28 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
apoptotic process GO:0006915 159 0.013
calcium ion homeostasis GO:0055074 23 0.013
nucleoside monophosphate metabolic process GO:0009123 52 0.013
female meiotic division GO:0007143 70 0.013
response to light stimulus GO:0009416 124 0.013
regulation of defense response GO:0031347 102 0.013
muscle organ development GO:0007517 127 0.013
regulation of translation GO:0006417 56 0.013
g protein coupled receptor signaling pathway GO:0007186 136 0.013
regulation of mrna processing GO:0050684 71 0.013
chemical homeostasis GO:0048878 92 0.013
biological adhesion GO:0022610 138 0.013
establishment of protein localization to organelle GO:0072594 62 0.013
multicellular organismal aging GO:0010259 140 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.012
post embryonic appendage morphogenesis GO:0035120 385 0.012
regulation of cell differentiation GO:0045595 302 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
dna methylation or demethylation GO:0044728 4 0.012
response to radiation GO:0009314 155 0.012
macromolecule deacylation GO:0098732 11 0.012
dna dependent dna replication GO:0006261 17 0.012
regulation of protein targeting GO:1903533 29 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
centriole replication GO:0007099 24 0.012
peptidyl tyrosine modification GO:0018212 24 0.012
purine nucleoside monophosphate metabolic process GO:0009126 50 0.012
nucleolus organization GO:0007000 4 0.012
jak stat cascade GO:0007259 49 0.012
secretion GO:0046903 109 0.012
regulation of smoothened signaling pathway GO:0008589 28 0.012
proteolysis GO:0006508 192 0.012
salivary gland development GO:0007431 162 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
heart morphogenesis GO:0003007 32 0.011
response to unfolded protein GO:0006986 9 0.011
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 1 0.011
actin filament based process GO:0030029 220 0.011
macromolecule catabolic process GO:0009057 161 0.011
signal transduction in response to dna damage GO:0042770 3 0.011
cell growth GO:0016049 108 0.011
protein dephosphorylation GO:0006470 27 0.011
heart contraction GO:0060047 26 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
positive regulation of lipid catabolic process GO:0050996 1 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
regulation of cell shape GO:0008360 113 0.011
purine containing compound catabolic process GO:0072523 112 0.011
tissue migration GO:0090130 155 0.011
negative regulation of molecular function GO:0044092 51 0.011
cellular amine metabolic process GO:0044106 12 0.011
circulatory system process GO:0003013 37 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
convergent extension GO:0060026 2 0.011
tube morphogenesis GO:0035239 191 0.011
gene silencing by rna GO:0031047 57 0.011
inositol lipid mediated signaling GO:0048017 4 0.011
response to ethanol GO:0045471 59 0.011
intracellular transport GO:0046907 228 0.010
compound eye development GO:0048749 307 0.010
regulation of nucleoside metabolic process GO:0009118 50 0.010
single organism catabolic process GO:0044712 228 0.010
organophosphate catabolic process GO:0046434 112 0.010
regulation of endopeptidase activity GO:0052548 36 0.010
regulation of programmed cell death GO:0043067 152 0.010
dna duplex unwinding GO:0032508 16 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
posttranscriptional gene silencing by rna GO:0035194 45 0.010
response to purine containing compound GO:0014074 12 0.010
cellular ketone metabolic process GO:0042180 24 0.010
response to lipid GO:0033993 38 0.010
positive regulation of cellular component biogenesis GO:0044089 80 0.010
regulation of response to stress GO:0080134 200 0.010
digestive system development GO:0055123 149 0.010
meiotic spindle organization GO:0000212 36 0.010
cell aging GO:0007569 2 0.010
head involution GO:0008258 35 0.010
cell adhesion GO:0007155 136 0.010

dmt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.040
disease of metabolism DOID:0014667 0 0.020
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.011