Drosophila melanogaster

276 known processes

Gef26 (Dmel_CG9491)

CG9491 gene product from transcript CG9491-RB

(Aliases: PDZ-GEF,Dmel\CG9491,PDF-GEF Dizzy,l(2)k13720,dizzy,CG9491,dPDZ-GEF,GEF,dzy)

Gef26 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 323 0.873
compound eye morphogenesis GO:0001745 249 0.704
sensory organ morphogenesis GO:0090596 260 0.644
photoreceptor cell differentiation GO:0046530 170 0.618
cortical actin cytoskeleton organization GO:0030866 24 0.616
germ line stem cell maintenance GO:0030718 50 0.522
homeostatic process GO:0042592 199 0.444
biological adhesion GO:0022610 138 0.442
post embryonic appendage morphogenesis GO:0035120 385 0.435
chromosome organization GO:0051276 360 0.398
axon development GO:0061564 297 0.379
compound eye development GO:0048749 307 0.374
cell adhesion GO:0007155 136 0.345
regulation of cell development GO:0060284 215 0.344
spermatid development GO:0007286 98 0.335
chemotaxis GO:0006935 249 0.322
tissue morphogenesis GO:0048729 297 0.314
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.309
eye morphogenesis GO:0048592 260 0.289
localization of cell GO:0051674 257 0.277
regulation of anatomical structure morphogenesis GO:0022603 242 0.257
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.254
photoreceptor cell development GO:0042461 96 0.246
central nervous system development GO:0007417 201 0.245
Mouse
regulation of proteolysis GO:0030162 87 0.241
single organism cell adhesion GO:0098602 47 0.229
spermatogenesis GO:0007283 200 0.222
asymmetric cell division GO:0008356 37 0.220
compound eye photoreceptor cell differentiation GO:0001751 140 0.219
neuron projection guidance GO:0097485 241 0.219
imaginal disc derived appendage morphogenesis GO:0035114 395 0.219
imaginal disc derived appendage development GO:0048737 399 0.212
regulation of growth GO:0040008 233 0.211
adherens junction organization GO:0034332 27 0.210
actin cytoskeleton organization GO:0030036 206 0.208
transcription from rna polymerase ii promoter GO:0006366 368 0.203
negative regulation of gene expression GO:0010629 387 0.196
autophagy GO:0006914 108 0.195
appendage development GO:0048736 401 0.194
stem cell maintenance GO:0019827 67 0.190
establishment or maintenance of cell polarity GO:0007163 167 0.186
single organismal cell cell adhesion GO:0016337 45 0.186
synaptic transmission GO:0007268 288 0.175
small molecule metabolic process GO:0044281 305 0.174
regulation of cellular component biogenesis GO:0044087 201 0.170
Human
male gamete generation GO:0048232 201 0.170
morphogenesis of an epithelium GO:0002009 276 0.166
regulation of cellular catabolic process GO:0031329 157 0.165
cell migration GO:0016477 238 0.165
positive regulation of cellular component biogenesis GO:0044089 80 0.163
eye photoreceptor cell development GO:0042462 81 0.162
growth GO:0040007 359 0.162
camera type eye development GO:0043010 4 0.159
wing disc morphogenesis GO:0007472 344 0.158
regionalization GO:0003002 416 0.155
pole plasm mrna localization GO:0019094 49 0.155
single organism catabolic process GO:0044712 228 0.153
cell cell junction assembly GO:0007043 38 0.151
regulation of catabolic process GO:0009894 170 0.151
eye photoreceptor cell fate commitment GO:0042706 37 0.151
positive regulation of macromolecule metabolic process GO:0010604 405 0.150
Human Mouse
regulation of cell cycle GO:0051726 291 0.150
filtration diaphragm assembly GO:0036058 4 0.148
cell motility GO:0048870 251 0.147
cell proliferation GO:0008283 299 0.144
Human Mouse
compound eye photoreceptor fate commitment GO:0001752 36 0.144
actin filament bundle organization GO:0061572 28 0.141
actin filament bundle assembly GO:0051017 26 0.141
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.141
eye photoreceptor cell differentiation GO:0001754 145 0.140
positive regulation of rna metabolic process GO:0051254 271 0.138
regulation of endopeptidase activity GO:0052548 36 0.136
actin filament based process GO:0030029 220 0.135
positive regulation of rna biosynthetic process GO:1902680 266 0.131
purine containing compound metabolic process GO:0072521 155 0.131
brain development GO:0007420 120 0.130
Mouse
positive regulation of response to stimulus GO:0048584 323 0.127
Human Mouse
chromatin modification GO:0016568 147 0.126
maintenance of location GO:0051235 73 0.126
head development GO:0060322 135 0.125
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.124
positive regulation of nucleic acid templated transcription GO:1903508 266 0.123
appendage morphogenesis GO:0035107 397 0.122
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.122
actin filament organization GO:0007015 126 0.118
positive regulation of developmental process GO:0051094 143 0.117
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.113
imaginal disc derived wing vein specification GO:0007474 48 0.113
regulation of pole plasm oskar mrna localization GO:0007317 27 0.113
catabolic process GO:0009056 409 0.112
epithelial cell development GO:0002064 274 0.112
Human
regulation of proteasomal protein catabolic process GO:0061136 39 0.112
phosphorylation GO:0016310 294 0.111
protein localization GO:0008104 284 0.110
positive regulation of peptidase activity GO:0010952 29 0.108
exocrine system development GO:0035272 162 0.107
endodermal cell fate commitment GO:0001711 3 0.107
cell division GO:0051301 248 0.107
anterior posterior pattern specification GO:0009952 136 0.106
negative regulation of cellular metabolic process GO:0031324 382 0.104
Mouse
positive regulation of biosynthetic process GO:0009891 316 0.103
imaginal disc derived wing morphogenesis GO:0007476 337 0.103
chromatin organization GO:0006325 207 0.099
establishment of ommatidial planar polarity GO:0042067 49 0.099
tissue migration GO:0090130 155 0.098
immune response GO:0006955 246 0.097
regulation of cellular ketone metabolic process GO:0010565 3 0.096
regulation of cell adhesion GO:0030155 27 0.096
anatomical structure homeostasis GO:0060249 97 0.095
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.093
regulation of nervous system development GO:0051960 248 0.092
immune system development GO:0002520 57 0.090
proteolysis GO:0006508 192 0.090
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.089
digestive tract development GO:0048565 149 0.088
protein transport GO:0015031 155 0.088
response to heat GO:0009408 63 0.088
negative regulation of response to stimulus GO:0048585 258 0.088
regulation of response to stress GO:0080134 200 0.087
negative regulation of protein metabolic process GO:0051248 85 0.087
compound eye retinal cell programmed cell death GO:0046667 23 0.087
pole plasm rna localization GO:0007316 52 0.085
connective tissue development GO:0061448 3 0.084
tissue homeostasis GO:0001894 36 0.084
compound eye photoreceptor development GO:0042051 78 0.084
cellular protein modification process GO:0006464 438 0.083
Human Mouse
nucleobase containing compound catabolic process GO:0034655 165 0.080
ribonucleotide metabolic process GO:0009259 145 0.080
sensory perception GO:0007600 196 0.080
taxis GO:0042330 304 0.079
nucleoside metabolic process GO:0009116 127 0.079
wound healing GO:0042060 75 0.078
protein complex assembly GO:0006461 200 0.078
positive regulation of cellular biosynthetic process GO:0031328 316 0.078
retinal cell programmed cell death GO:0046666 25 0.078
immune system process GO:0002376 347 0.077
organic hydroxy compound metabolic process GO:1901615 83 0.077
Mouse
purine containing compound catabolic process GO:0072523 112 0.076
regulation of cell projection organization GO:0031344 92 0.075
Human Mouse
regulation of cell morphogenesis GO:0022604 163 0.074
neurological system process GO:0050877 358 0.074
regulation of cytoskeleton organization GO:0051493 89 0.073
response to abiotic stimulus GO:0009628 341 0.073
regulation of embryonic development GO:0045995 68 0.073
organelle localization GO:0051640 148 0.073
endocytosis GO:0006897 310 0.073
membrane organization GO:0061024 112 0.073
cellular homeostasis GO:0019725 80 0.071
protein complex biogenesis GO:0070271 201 0.071
maintenance of epithelial integrity open tracheal system GO:0035160 12 0.071
regulation of autophagy GO:0010506 62 0.070
erbb signaling pathway GO:0038127 58 0.070
intracellular signal transduction GO:0035556 300 0.069
cellular ketone metabolic process GO:0042180 24 0.069
developmental programmed cell death GO:0010623 138 0.069
chaeta development GO:0022416 97 0.068
hemocyte migration GO:0035099 19 0.068
regulation of multicellular organismal development GO:2000026 414 0.068
regulation of protein metabolic process GO:0051246 256 0.068
Human Mouse
purine nucleoside metabolic process GO:0042278 127 0.067
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.067
nucleoside phosphate catabolic process GO:1901292 110 0.067
regulation of response to external stimulus GO:0032101 115 0.066
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.065
cell cell junction organization GO:0045216 55 0.065
positive regulation of cell death GO:0010942 69 0.065
Human Mouse
cytoplasm organization GO:0007028 64 0.064
regulation of embryonic pattern specification GO:1902875 27 0.063
oocyte microtubule cytoskeleton organization GO:0016325 35 0.063
ameboidal type cell migration GO:0001667 151 0.062
axon guidance GO:0007411 233 0.062
axon target recognition GO:0007412 16 0.062
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.062
positive regulation of catabolic process GO:0009896 105 0.061
embryonic morphogenesis GO:0048598 206 0.061
organonitrogen compound metabolic process GO:1901564 318 0.061
heterochromatin organization GO:0070828 25 0.060
regulation of cell death GO:0010941 173 0.060
Human Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.060
purine ribonucleotide catabolic process GO:0009154 109 0.059
spermatid differentiation GO:0048515 114 0.059
regulation of epithelial cell differentiation GO:0030856 4 0.058
embryonic pattern specification GO:0009880 174 0.058
negative regulation of signal transduction GO:0009968 206 0.058
atp metabolic process GO:0046034 49 0.058
amine metabolic process GO:0009308 12 0.058
positive regulation of cell differentiation GO:0045597 64 0.057
Mouse
negative regulation of cell communication GO:0010648 223 0.056
pole plasm assembly GO:0007315 61 0.056
endodermal cell differentiation GO:0035987 3 0.056
segmentation GO:0035282 207 0.055
maternal determination of anterior posterior axis embryo GO:0008358 74 0.055
cell cell signaling involved in cell fate commitment GO:0045168 210 0.055
cellular macromolecular complex assembly GO:0034622 153 0.055
digestive tract morphogenesis GO:0048546 127 0.054
regulation of cellular amine metabolic process GO:0033238 3 0.054
cellular protein localization GO:0034613 160 0.054
cellular response to dna damage stimulus GO:0006974 223 0.053
cuticle pattern formation GO:0035017 27 0.053
sensory perception of sound GO:0007605 56 0.053
regulation of protein localization GO:0032880 76 0.052
antennal development GO:0007469 25 0.052
apoptotic cell clearance GO:0043277 14 0.052
anterior posterior axis specification embryo GO:0008595 103 0.052
morphogenesis of a polarized epithelium GO:0001738 93 0.052
negative regulation of developmental process GO:0051093 201 0.052
cellular catabolic process GO:0044248 372 0.051
embryonic axis specification GO:0000578 107 0.051
positive regulation of hydrolase activity GO:0051345 78 0.051
regulation of secretion by cell GO:1903530 39 0.051
epithelial cell differentiation GO:0030855 322 0.051
Human
macroautophagy GO:0016236 42 0.051
purine nucleoside catabolic process GO:0006152 112 0.050
establishment of organelle localization GO:0051656 122 0.050
organic substance catabolic process GO:1901575 308 0.050
cell junction assembly GO:0034329 42 0.050
purine nucleoside triphosphate catabolic process GO:0009146 108 0.050
regulation of cellular response to stress GO:0080135 89 0.049
male courtship behavior veined wing extension GO:0048065 22 0.049
regulation of cellular protein metabolic process GO:0032268 243 0.049
Human Mouse
histone modification GO:0016570 106 0.049
regulation of cell shape GO:0008360 113 0.049
stem cell differentiation GO:0048863 117 0.049
regulation of molecular function GO:0065009 217 0.049
nephrocyte diaphragm assembly GO:0036059 3 0.049
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.048
regulation of cellular amino acid metabolic process GO:0006521 0 0.048
glycosyl compound catabolic process GO:1901658 112 0.048
ribonucleoside catabolic process GO:0042454 112 0.048
ovarian follicle cell development GO:0030707 248 0.048
protein phosphorylation GO:0006468 169 0.047
Human Mouse
response to organic substance GO:0010033 284 0.047
Human Mouse
rna localization GO:0006403 115 0.047
mitotic cytokinesis GO:0000281 50 0.046
regulation of photoreceptor cell differentiation GO:0046532 34 0.046
adult chitin based cuticle development GO:0008365 2 0.046
phagocytosis GO:0006909 215 0.046
cell death GO:0008219 279 0.046
Human Mouse
regulation of protein complex assembly GO:0043254 42 0.045
positive regulation of gene expression GO:0010628 290 0.045
regulation of peptidase activity GO:0052547 39 0.045
lateral inhibition GO:0046331 206 0.045
negative regulation of cellular catabolic process GO:0031330 34 0.045
regulation of establishment of protein localization GO:0070201 61 0.044
protein processing GO:0016485 68 0.044
macromolecular complex assembly GO:0065003 256 0.044
negative regulation of cytoskeleton organization GO:0051494 30 0.044
response to oxygen containing compound GO:1901700 200 0.043
Human Mouse
dorsal appendage formation GO:0046843 47 0.043
cellular chemical homeostasis GO:0055082 40 0.043
mitotic spindle organization GO:0007052 220 0.043
mesoderm morphogenesis GO:0048332 22 0.043
purine nucleotide catabolic process GO:0006195 109 0.042
signal transduction by phosphorylation GO:0023014 107 0.042
positive regulation of cellular component organization GO:0051130 156 0.042
regulation of actin filament based process GO:0032970 42 0.042
establishment of localization in cell GO:0051649 402 0.042
protein maturation GO:0051604 71 0.042
ommatidial rotation GO:0016318 20 0.042
endoderm formation GO:0001706 3 0.041
positive regulation of cell communication GO:0010647 250 0.041
Human Mouse
wnt signaling pathway GO:0016055 98 0.041
vesicle mediated transport GO:0016192 381 0.041
glycosyl compound metabolic process GO:1901657 127 0.041
oocyte axis specification GO:0007309 108 0.041
germarium derived egg chamber formation GO:0007293 101 0.041
oocyte anterior posterior axis specification GO:0007314 72 0.040
apoptotic process involved in morphogenesis GO:0060561 3 0.040
single organism cellular localization GO:1902580 180 0.040
regulation of localization GO:0032879 275 0.040
Mouse
positive regulation of epithelial cell differentiation GO:0030858 1 0.040
synapse organization GO:0050808 196 0.040
positive regulation of protein secretion GO:0050714 9 0.039
regulation of wnt signaling pathway GO:0030111 68 0.039
male courtship behavior veined wing generated song production GO:0045433 20 0.039
morphogenesis of follicular epithelium GO:0016333 36 0.039
protein modification process GO:0036211 438 0.039
Human Mouse
regulation of cellular component movement GO:0051270 42 0.039
Mouse
gliogenesis GO:0042063 80 0.039
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.039
hematopoietic or lymphoid organ development GO:0048534 57 0.039
regulation of immune response GO:0050776 118 0.039
positive regulation of cell development GO:0010720 61 0.038
Mouse
adherens junction assembly GO:0034333 11 0.038
digestive system development GO:0055123 149 0.038
epidermal cell differentiation GO:0009913 51 0.038
regulation of transport GO:0051049 181 0.038
axis specification GO:0009798 167 0.038
chitin based cuticle development GO:0040003 49 0.037
telencephalon development GO:0021537 2 0.037
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.037
regulation of anatomical structure size GO:0090066 163 0.037
fusion cell fate specification GO:0035156 4 0.037
organic acid metabolic process GO:0006082 103 0.037
positive regulation of cell migration GO:0030335 2 0.037
Mouse
ribonucleoside metabolic process GO:0009119 127 0.037
embryo development ending in birth or egg hatching GO:0009792 152 0.037
regulation of cell cell adhesion GO:0022407 21 0.037
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.037
regulation of mitotic cell cycle GO:0007346 190 0.036
oocyte construction GO:0007308 112 0.036
negative regulation of cellular component organization GO:0051129 108 0.036
Human Mouse
positive regulation of organelle organization GO:0010638 65 0.036
pole plasm oskar mrna localization GO:0045451 46 0.036
head involution GO:0008258 35 0.036
negative regulation of proteolysis GO:0045861 31 0.036
regulation of eye photoreceptor cell development GO:0042478 13 0.036
cortical cytoskeleton organization GO:0030865 29 0.036
regulation of protein transport GO:0051223 57 0.036
ribose phosphate metabolic process GO:0019693 145 0.035
establishment of protein localization GO:0045184 163 0.035
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.035
motor neuron axon guidance GO:0008045 58 0.034
tripartite regional subdivision GO:0007351 103 0.034
epidermal growth factor receptor signaling pathway GO:0007173 58 0.034
response to radiation GO:0009314 155 0.034
ribonucleoside monophosphate catabolic process GO:0009158 39 0.034
regulation of programmed cell death GO:0043067 152 0.034
Human Mouse
death GO:0016265 284 0.034
Human Mouse
negative regulation of intracellular signal transduction GO:1902532 57 0.034
forebrain development GO:0030900 2 0.034
Mouse
actomyosin structure organization GO:0031032 56 0.034
mapk cascade GO:0000165 107 0.034
cytokinesis GO:0000910 90 0.034
lipid metabolic process GO:0006629 121 0.034
blastoderm segmentation GO:0007350 159 0.034
negative regulation of rna metabolic process GO:0051253 251 0.033
planar cell polarity pathway involved in axis elongation GO:0003402 3 0.033
regulation of microtubule cytoskeleton organization GO:0070507 41 0.033
aromatic compound catabolic process GO:0019439 166 0.033
negative regulation of cellular protein metabolic process GO:0032269 85 0.033
ovarian follicle cell stalk formation GO:0030713 17 0.033
regulation of cellular protein catabolic process GO:1903362 44 0.033
nucleus localization GO:0051647 34 0.032
positive regulation of cell motility GO:2000147 3 0.032
Mouse
covalent chromatin modification GO:0016569 106 0.032
zonula adherens assembly GO:0045186 6 0.032
retina development in camera type eye GO:0060041 4 0.032
cellular amino acid metabolic process GO:0006520 61 0.031
lamellipodium organization GO:0097581 21 0.031
instar larval development GO:0002168 55 0.031
embryonic development via the syncytial blastoderm GO:0001700 148 0.031
substrate dependent cell migration cell extension GO:0006930 3 0.031
negative regulation of protein depolymerization GO:1901880 23 0.031
nucleotide catabolic process GO:0009166 109 0.031
single organism intracellular transport GO:1902582 207 0.031
oocyte development GO:0048599 124 0.031
positive regulation of signal transduction GO:0009967 223 0.031
Human Mouse
gland morphogenesis GO:0022612 145 0.030
purine ribonucleotide metabolic process GO:0009150 145 0.030
garland nephrocyte differentiation GO:0061321 3 0.030
positive regulation of cellular protein metabolic process GO:0032270 118 0.030
Human Mouse
embryonic hemopoiesis GO:0035162 26 0.030
regulation of erbb signaling pathway GO:1901184 42 0.030
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.030
stem cell development GO:0048864 79 0.030
transposition rna mediated GO:0032197 3 0.030
synapse assembly GO:0007416 143 0.029
oxoacid metabolic process GO:0043436 103 0.029
positive regulation of stem cell differentiation GO:2000738 3 0.029
body morphogenesis GO:0010171 2 0.029
epithelium migration GO:0090132 148 0.029
regulation of cellular localization GO:0060341 136 0.029
regulation of cell projection assembly GO:0060491 30 0.029
nucleobase containing small molecule metabolic process GO:0055086 174 0.029
immune effector process GO:0002252 98 0.029
locomotory behavior GO:0007626 176 0.028
response to temperature stimulus GO:0009266 106 0.028
sex differentiation GO:0007548 81 0.028
regulation of nuclear division GO:0051783 58 0.028
cellular amine metabolic process GO:0044106 12 0.028
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.028
positive regulation of proteolysis GO:0045862 52 0.028
peptidyl threonine phosphorylation GO:0018107 2 0.028
purine nucleotide metabolic process GO:0006163 146 0.028
protein secretion GO:0009306 45 0.028
lipid storage GO:0019915 38 0.027
cellular macromolecule localization GO:0070727 220 0.027
regulation of dna templated transcription elongation GO:0032784 17 0.027
cystoblast division GO:0007282 10 0.027
regulation of phosphorus metabolic process GO:0051174 210 0.027
purine ribonucleoside metabolic process GO:0046128 127 0.027
hindgut development GO:0061525 58 0.027
nucleoside phosphate metabolic process GO:0006753 162 0.027
negative regulation of epithelial cell proliferation GO:0050680 4 0.027
negative regulation of endopeptidase activity GO:0010951 11 0.027
heterocycle catabolic process GO:0046700 166 0.027
anterior posterior axis specification GO:0009948 109 0.027
cell fate determination GO:0001709 91 0.026
negative regulation of transcription dna templated GO:0045892 237 0.026
negative regulation of protein complex disassembly GO:0043242 23 0.026
mitotic sister chromatid segregation GO:0000070 87 0.026
intercellular bridge organization GO:0043063 14 0.026
eye antennal disc development GO:0035214 60 0.026
chaeta morphogenesis GO:0008407 42 0.026
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.026
negative regulation of chromosome organization GO:2001251 19 0.026
ribonucleotide catabolic process GO:0009261 109 0.026
epidermis development GO:0008544 65 0.026
Worm
organic substance transport GO:0071702 257 0.026
filopodium assembly GO:0046847 33 0.026
molting cycle GO:0042303 56 0.026
Worm
regulation of microtubule based process GO:0032886 49 0.026
detection of external stimulus GO:0009581 66 0.026
hemopoiesis GO:0030097 46 0.026
sperm individualization GO:0007291 48 0.025
posttranscriptional gene silencing by rna GO:0035194 45 0.025
aging GO:0007568 143 0.025
regulation of hydrolase activity GO:0051336 97 0.025
tube development GO:0035295 244 0.025
purine nucleoside monophosphate metabolic process GO:0009126 50 0.025
negative regulation of cell cycle GO:0045786 116 0.025
cellular response to extracellular stimulus GO:0031668 64 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.025
hindbrain development GO:0030902 2 0.025
regulation of actin filament length GO:0030832 27 0.025
regulation of cell cycle process GO:0010564 181 0.025
programmed cell death GO:0012501 257 0.025
Human Mouse
posttranscriptional regulation of gene expression GO:0010608 145 0.024
parallel actin filament bundle assembly GO:0030046 2 0.024
regulation of organelle organization GO:0033043 196 0.024
regulation of cell division GO:0051302 72 0.024
carbohydrate derivative catabolic process GO:1901136 118 0.024
positive regulation of insulin receptor signaling pathway GO:0046628 3 0.024
dna templated transcription elongation GO:0006354 18 0.024
regulation of cell differentiation GO:0045595 302 0.024
post embryonic hemopoiesis GO:0035166 17 0.024
negative regulation of protein phosphorylation GO:0001933 17 0.024
dorsal closure GO:0007391 79 0.024
substrate dependent cell migration GO:0006929 3 0.024
organophosphate catabolic process GO:0046434 112 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.024
regulation of embryonic cell shape GO:0016476 30 0.023
negative regulation of cell differentiation GO:0045596 143 0.023
organ growth GO:0035265 56 0.023
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.023
response to hypoxia GO:0001666 53 0.023
regulation of cell maturation GO:1903429 27 0.023
female gonad development GO:0008585 12 0.023
convergent extension GO:0060026 2 0.023
small gtpase mediated signal transduction GO:0007264 88 0.023
Human
cell fate determination involved in pattern specification GO:0060582 19 0.023
regulation of oocyte development GO:0060281 27 0.023
lipid localization GO:0010876 54 0.023
gland development GO:0048732 191 0.023
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 3 0.023
actin filament based movement GO:0030048 26 0.023
negative regulation of catabolic process GO:0009895 36 0.023
negative regulation of cell cell adhesion GO:0022408 8 0.023
regulation of actin cytoskeleton organization GO:0032956 42 0.023
nuclear division GO:0000280 332 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
negative regulation of phosphorylation GO:0042326 35 0.023
muscle cell differentiation GO:0042692 103 0.023
ribonucleoside triphosphate catabolic process GO:0009203 108 0.023
negative regulation of biosynthetic process GO:0009890 277 0.022
Mouse
nucleotide metabolic process GO:0009117 161 0.022
regulation of synapse assembly GO:0051963 94 0.022
activation of cysteine type endopeptidase activity GO:0097202 17 0.022
hair cell differentiation GO:0035315 47 0.022
male courtship behavior veined wing vibration GO:0016545 21 0.022
imaginal disc derived wing hair site selection GO:0035320 4 0.022
ribonucleoside triphosphate metabolic process GO:0009199 119 0.022
negative regulation of cell death GO:0060548 81 0.022
morphogenesis of embryonic epithelium GO:0016331 94 0.022
regulation of immune system process GO:0002682 176 0.022
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.022
intracellular transport GO:0046907 228 0.022
regulation of actin polymerization or depolymerization GO:0008064 27 0.022
cell cell adhesion GO:0098609 26 0.021
cell growth GO:0016049 108 0.021
cell cell adhesion mediated by cadherin GO:0044331 6 0.021
ribonucleoside monophosphate metabolic process GO:0009161 51 0.021
negative regulation of organelle organization GO:0010639 56 0.021
apoptotic process GO:0006915 159 0.021
Human Mouse
regulation of epidermal cell differentiation GO:0045604 3 0.021
spindle organization GO:0007051 253 0.021
positive regulation of programmed cell death GO:0043068 62 0.021
Human Mouse
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.021
regulation of phosphorylation GO:0042325 147 0.021
Human Mouse
establishment of tissue polarity GO:0007164 87 0.021
convergent extension involved in gastrulation GO:0060027 2 0.021
reproductive system development GO:0061458 74 0.020
kidney development GO:0001822 3 0.020
purine ribonucleoside catabolic process GO:0046130 112 0.020
cell maturation GO:0048469 144 0.020
response to other organism GO:0051707 293 0.020
multicellular organismal homeostasis GO:0048871 41 0.020
ovarian follicle cell migration GO:0007297 121 0.020
nucleoside monophosphate metabolic process GO:0009123 52 0.020
response to biotic stimulus GO:0009607 294 0.020
mating GO:0007618 120 0.020
male courtship behavior GO:0008049 63 0.020

Gef26 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.239
nervous system disease DOID:863 0 0.061