Drosophila melanogaster

35 known processes

Pez (Dmel_CG9493)

CG9493 gene product from transcript CG9493-RA

(Aliases: Dmel\CG9493,PTPD1,CG9493)

Pez biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell migration GO:0016477 238 0.378
response to organic substance GO:0010033 284 0.366
cellular response to chemical stimulus GO:0070887 199 0.358
response to endogenous stimulus GO:0009719 119 0.347
small molecule metabolic process GO:0044281 305 0.341
regulation of multicellular organismal development GO:2000026 414 0.307
localization of cell GO:0051674 257 0.287
head development GO:0060322 135 0.278
regulation of cell differentiation GO:0045595 302 0.261
regulation of cell proliferation GO:0042127 163 0.256
positive regulation of multicellular organismal process GO:0051240 143 0.239
negative regulation of biosynthetic process GO:0009890 277 0.193
cell proliferation GO:0008283 299 0.183
morphogenesis of an epithelium GO:0002009 276 0.178
cellular response to endogenous stimulus GO:0071495 80 0.169
response to organonitrogen compound GO:0010243 75 0.169
synapse organization GO:0050808 196 0.168
gtp catabolic process GO:0006184 72 0.163
cellular response to organic substance GO:0071310 132 0.162
regulation of apoptotic process GO:0042981 130 0.155
regulation of cell development GO:0060284 215 0.152
negative regulation of signal transduction GO:0009968 206 0.150
developmental growth GO:0048589 280 0.147
regulation of neurogenesis GO:0050767 158 0.146
photoreceptor cell differentiation GO:0046530 170 0.144
intracellular signal transduction GO:0035556 300 0.143
eye morphogenesis GO:0048592 260 0.142
cell motility GO:0048870 251 0.141
gtp metabolic process GO:0046039 72 0.140
regulation of growth GO:0040008 233 0.135
regulation of cellular ketone metabolic process GO:0010565 3 0.135
regulation of nervous system development GO:0051960 248 0.132
positive regulation of developmental process GO:0051094 143 0.130
negative regulation of signaling GO:0023057 219 0.129
immune response GO:0006955 246 0.128
growth GO:0040007 359 0.126
regionalization GO:0003002 416 0.123
regulation of neuron differentiation GO:0045664 103 0.119
positive regulation of rna metabolic process GO:0051254 271 0.117
apoptotic process GO:0006915 159 0.115
regulation of protein metabolic process GO:0051246 256 0.114
response to oxygen containing compound GO:1901700 200 0.109
purine nucleoside catabolic process GO:0006152 112 0.108
regulation of cellular component biogenesis GO:0044087 201 0.106
blastoderm segmentation GO:0007350 159 0.105
tissue morphogenesis GO:0048729 297 0.105
regulation of synapse assembly GO:0051963 94 0.103
purine ribonucleotide catabolic process GO:0009154 109 0.098
appendage morphogenesis GO:0035107 397 0.098
ovarian follicle cell development GO:0030707 248 0.098
single organismal cell cell adhesion GO:0016337 45 0.097
notch signaling pathway GO:0007219 120 0.095
nucleoside triphosphate catabolic process GO:0009143 108 0.095
organelle localization GO:0051640 148 0.094
enzyme linked receptor protein signaling pathway GO:0007167 179 0.092
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.092
positive regulation of cellular component biogenesis GO:0044089 80 0.091
cellular response to peptide hormone stimulus GO:0071375 28 0.090
regulation of synapse structure and activity GO:0050803 128 0.090
vesicle mediated transport GO:0016192 381 0.089
embryonic morphogenesis GO:0048598 206 0.086
negative regulation of rna metabolic process GO:0051253 251 0.085
regulation of organelle organization GO:0033043 196 0.085
regulation of developmental growth GO:0048638 174 0.084
regulation of cellular amino acid metabolic process GO:0006521 0 0.084
stem cell proliferation GO:0072089 88 0.084
embryonic pattern specification GO:0009880 174 0.082
cellular ketone metabolic process GO:0042180 24 0.081
positive regulation of cellular component organization GO:0051130 156 0.080
regulation of molecular function GO:0065009 217 0.080
positive regulation of response to stimulus GO:0048584 323 0.078
regulation of synapse organization GO:0050807 110 0.076
guanosine containing compound catabolic process GO:1901069 74 0.075
defense response to bacterium GO:0042742 178 0.074
negative regulation of cellular biosynthetic process GO:0031327 277 0.074
heterocycle catabolic process GO:0046700 166 0.073
small gtpase mediated signal transduction GO:0007264 88 0.073
post embryonic appendage morphogenesis GO:0035120 385 0.073
guanosine containing compound metabolic process GO:1901068 74 0.070
regulation of nucleotide catabolic process GO:0030811 48 0.069
sensory organ morphogenesis GO:0090596 260 0.068
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.068
macromolecular complex assembly GO:0065003 256 0.067
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.067
regulation of notch signaling pathway GO:0008593 100 0.064
negative regulation of developmental process GO:0051093 201 0.063
cellular response to peptide GO:1901653 28 0.063
actin filament based process GO:0030029 220 0.061
single organism behavior GO:0044708 391 0.061
taxis GO:0042330 304 0.061
purine containing compound catabolic process GO:0072523 112 0.061
positive regulation of cell communication GO:0010647 250 0.060
aging GO:0007568 143 0.060
biological adhesion GO:0022610 138 0.060
regulation of cellular localization GO:0060341 136 0.059
Human
endocytosis GO:0006897 310 0.059
actin cytoskeleton organization GO:0030036 206 0.056
imaginal disc derived appendage development GO:0048737 399 0.055
cellular nitrogen compound catabolic process GO:0044270 165 0.055
negative regulation of cell proliferation GO:0008285 69 0.055
negative regulation of multicellular organismal process GO:0051241 142 0.054
cardiovascular system development GO:0072358 82 0.054
Human Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.053
response to nitrogen compound GO:1901698 90 0.053
cellular amine metabolic process GO:0044106 12 0.053
ribose phosphate metabolic process GO:0019693 145 0.052
negative regulation of response to stimulus GO:0048585 258 0.050
axonogenesis GO:0007409 290 0.049
appendage development GO:0048736 401 0.049
regulation of cellular protein metabolic process GO:0032268 243 0.049
positive regulation of nucleotide metabolic process GO:0045981 55 0.049
regulation of response to stress GO:0080134 200 0.049
organic cyclic compound catabolic process GO:1901361 168 0.048
positive regulation of cellular amine metabolic process GO:0033240 0 0.048
imaginal disc derived appendage morphogenesis GO:0035114 395 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.048
phagocytosis GO:0006909 215 0.048
response to external biotic stimulus GO:0043207 293 0.047
organic substance catabolic process GO:1901575 308 0.047
positive regulation of nucleic acid templated transcription GO:1903508 266 0.046
nucleoside catabolic process GO:0009164 112 0.045
negative regulation of cell communication GO:0010648 223 0.045
organophosphate metabolic process GO:0019637 195 0.044
establishment or maintenance of cell polarity GO:0007163 167 0.044
organic acid metabolic process GO:0006082 103 0.044
actin filament organization GO:0007015 126 0.044
regulation of anatomical structure morphogenesis GO:0022603 242 0.043
eye photoreceptor cell differentiation GO:0001754 145 0.043
positive regulation of signal transduction GO:0009967 223 0.043
protein complex assembly GO:0006461 200 0.043
embryonic organ development GO:0048568 50 0.043
anterior posterior pattern specification GO:0009952 136 0.043
body morphogenesis GO:0010171 2 0.043
nucleotide catabolic process GO:0009166 109 0.042
periodic partitioning GO:0007365 29 0.042
cellular response to organonitrogen compound GO:0071417 36 0.042
epithelial cell migration GO:0010631 148 0.042
regulation of cell death GO:0010941 173 0.042
positive regulation of rna biosynthetic process GO:1902680 266 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.042
regulation of localization GO:0032879 275 0.041
Human
transcription from rna polymerase ii promoter GO:0006366 368 0.041
regulation of cell projection organization GO:0031344 92 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.041
regulation of nucleotide metabolic process GO:0006140 62 0.041
purine nucleotide catabolic process GO:0006195 109 0.040
erbb signaling pathway GO:0038127 58 0.040
regulation of ras gtpase activity GO:0032318 38 0.040
positive regulation of molecular function GO:0044093 136 0.040
morphogenesis of embryonic epithelium GO:0016331 94 0.039
negative regulation of cellular metabolic process GO:0031324 382 0.039
purine nucleoside triphosphate metabolic process GO:0009144 119 0.038
immune system process GO:0002376 347 0.038
cellular response to sterol depletion GO:0071501 3 0.038
organic substance transport GO:0071702 257 0.037
Human
ras protein signal transduction GO:0007265 88 0.037
peptidyl amino acid modification GO:0018193 105 0.037
mushroom body development GO:0016319 70 0.036
negative regulation of transcription dna templated GO:0045892 237 0.036
organonitrogen compound catabolic process GO:1901565 128 0.036
regulation of programmed cell death GO:0043067 152 0.036
carbohydrate derivative catabolic process GO:1901136 118 0.036
purine ribonucleotide metabolic process GO:0009150 145 0.035
rho protein signal transduction GO:0007266 14 0.035
developmental maturation GO:0021700 172 0.035
cell cell signaling involved in cell fate commitment GO:0045168 210 0.035
positive regulation of cellular protein metabolic process GO:0032270 118 0.035
eye development GO:0001654 323 0.034
chemotaxis GO:0006935 249 0.034
death GO:0016265 284 0.034
leg disc morphogenesis GO:0007478 80 0.034
cell death GO:0008219 279 0.034
innate immune response GO:0045087 144 0.034
response to alcohol GO:0097305 95 0.034
regulation of hydrolase activity GO:0051336 97 0.033
regulation of rac protein signal transduction GO:0035020 3 0.033
segmentation GO:0035282 207 0.033
carbohydrate derivative metabolic process GO:1901135 217 0.033
cell fate specification GO:0001708 71 0.033
respiratory system development GO:0060541 213 0.032
regulation of small gtpase mediated signal transduction GO:0051056 93 0.032
positive regulation of signaling GO:0023056 243 0.032
positive regulation of protein metabolic process GO:0051247 128 0.032
anatomical structure homeostasis GO:0060249 97 0.032
ribonucleotide metabolic process GO:0009259 145 0.032
purine nucleotide metabolic process GO:0006163 146 0.032
lateral inhibition GO:0046331 206 0.032
negative regulation of gene expression GO:0010629 387 0.031
single organism biosynthetic process GO:0044711 206 0.031
amine metabolic process GO:0009308 12 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.030
regulation of anatomical structure size GO:0090066 163 0.030
single organism catabolic process GO:0044712 228 0.029
negative regulation of cell differentiation GO:0045596 143 0.029
mitotic spindle organization GO:0007052 220 0.029
synaptic growth at neuromuscular junction GO:0051124 119 0.029
positive regulation of biosynthetic process GO:0009891 316 0.028
programmed cell death GO:0012501 257 0.028
central nervous system development GO:0007417 201 0.028
circulatory system development GO:0072359 82 0.028
Human Mouse
multi organism reproductive behavior GO:0044705 121 0.028
brain development GO:0007420 120 0.028
multicellular organismal homeostasis GO:0048871 41 0.028
embryonic development via the syncytial blastoderm GO:0001700 148 0.027
positive regulation of rho gtpase activity GO:0032321 19 0.027
ribonucleotide catabolic process GO:0009261 109 0.027
single organism cell adhesion GO:0098602 47 0.026
jak stat cascade GO:0007259 49 0.026
positive regulation of phosphorus metabolic process GO:0010562 139 0.026
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.026
positive regulation of cell differentiation GO:0045597 64 0.026
adult behavior GO:0030534 137 0.025
tube development GO:0035295 244 0.025
protein modification process GO:0036211 438 0.025
Human Rat
oocyte development GO:0048599 124 0.025
organonitrogen compound biosynthetic process GO:1901566 117 0.025
cellular protein modification process GO:0006464 438 0.025
Human Rat
compound eye morphogenesis GO:0001745 249 0.025
organonitrogen compound metabolic process GO:1901564 318 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.025
neuron projection guidance GO:0097485 241 0.025
positive regulation of gtp catabolic process GO:0033126 43 0.024
purine ribonucleoside metabolic process GO:0046128 127 0.024
negative regulation of rna biosynthetic process GO:1902679 240 0.024
regulation of cellular amine metabolic process GO:0033238 3 0.024
lipid metabolic process GO:0006629 121 0.024
cellular response to hormone stimulus GO:0032870 44 0.024
nucleotide metabolic process GO:0009117 161 0.024
circadian rhythm GO:0007623 105 0.023
peptidyl tyrosine modification GO:0018212 24 0.023
single organism cellular localization GO:1902580 180 0.023
positive regulation of protein modification process GO:0031401 58 0.023
cellular response to nitrogen compound GO:1901699 51 0.023
nucleoside phosphate catabolic process GO:1901292 110 0.023
regulation of ras protein signal transduction GO:0046578 93 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.023
histone modification GO:0016570 106 0.023
response to peptide GO:1901652 29 0.023
purine ribonucleoside catabolic process GO:0046130 112 0.023
compound eye development GO:0048749 307 0.023
eye photoreceptor cell fate commitment GO:0042706 37 0.023
connective tissue development GO:0061448 3 0.023
internal protein amino acid acetylation GO:0006475 38 0.022
response to biotic stimulus GO:0009607 294 0.022
protein acetylation GO:0006473 39 0.022
positive regulation of phosphate metabolic process GO:0045937 139 0.022
negative regulation of neurogenesis GO:0050768 53 0.022
aromatic compound catabolic process GO:0019439 166 0.022
wnt signaling pathway GO:0016055 98 0.022
positive regulation of gtpase activity GO:0043547 43 0.022
establishment of localization in cell GO:0051649 402 0.022
Human
cell adhesion GO:0007155 136 0.021
ribonucleoside triphosphate catabolic process GO:0009203 108 0.021
regulation of nucleoside metabolic process GO:0009118 50 0.021
carboxylic acid metabolic process GO:0019752 92 0.021
renal system development GO:0072001 72 0.021
telencephalon development GO:0021537 2 0.021
purine containing compound metabolic process GO:0072521 155 0.021
nucleoside metabolic process GO:0009116 127 0.021
positive regulation of nervous system development GO:0051962 69 0.021
positive regulation of gene expression GO:0010628 290 0.021
negative regulation of notch signaling pathway GO:0045746 41 0.021
glycosyl compound catabolic process GO:1901658 112 0.020
axon development GO:0061564 297 0.020
regulation of transport GO:0051049 181 0.020
Human
negative regulation of apoptotic process GO:0043066 63 0.020
protein ubiquitination GO:0016567 70 0.020
cellular catabolic process GO:0044248 372 0.020
catabolic process GO:0009056 409 0.020
cellular response to oxygen containing compound GO:1901701 79 0.020
immune system development GO:0002520 57 0.020
response to organophosphorus GO:0046683 2 0.020
camera type eye development GO:0043010 4 0.020
regulation of immune response GO:0050776 118 0.019
gliogenesis GO:0042063 80 0.019
cell activation GO:0001775 9 0.019
regulation of gtp catabolic process GO:0033124 44 0.019
regulation of immune system process GO:0002682 176 0.019
larval development GO:0002164 104 0.019
regulation of catabolic process GO:0009894 170 0.019
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.019
cellular lipid metabolic process GO:0044255 83 0.019
cell type specific apoptotic process GO:0097285 38 0.019
ribonucleoside metabolic process GO:0009119 127 0.019
regulation of protein modification process GO:0031399 112 0.018
response to peptide hormone GO:0043434 29 0.018
compound eye photoreceptor cell differentiation GO:0001751 140 0.018
regulation of catalytic activity GO:0050790 185 0.018
purine nucleoside triphosphate catabolic process GO:0009146 108 0.018
response to hormone GO:0009725 45 0.018
cellular response to insulin stimulus GO:0032869 28 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
response to organic cyclic compound GO:0014070 89 0.018
oxoacid metabolic process GO:0043436 103 0.017
positive regulation of intracellular signal transduction GO:1902533 116 0.017
defense response to fungus GO:0050832 48 0.017
regulation of protein localization GO:0032880 76 0.017
Human
positive regulation of cellular biosynthetic process GO:0031328 316 0.017
phosphorylation GO:0016310 294 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
establishment of organelle localization GO:0051656 122 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
positive regulation of cellular catabolic process GO:0031331 95 0.017
open tracheal system development GO:0007424 204 0.017
regulation of cell cycle GO:0051726 291 0.017
positive regulation of multicellular organism growth GO:0040018 21 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
positive regulation of growth GO:0045927 75 0.017
purine nucleoside metabolic process GO:0042278 127 0.017
spindle organization GO:0007051 253 0.017
epithelial cell development GO:0002064 274 0.017
positive regulation of macromolecule metabolic process GO:0010604 405 0.017
response to other organism GO:0051707 293 0.017
regulation of intracellular signal transduction GO:1902531 236 0.016
negative regulation of cell cycle phase transition GO:1901988 103 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
wing disc morphogenesis GO:0007472 344 0.016
regulation of erbb signaling pathway GO:1901184 42 0.016
chaeta development GO:0022416 97 0.016
regulation of cell migration GO:0030334 22 0.016
regulation of neuron projection development GO:0010975 69 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.016
wound healing GO:0042060 75 0.015
leg disc development GO:0035218 92 0.015
defense response to gram negative bacterium GO:0050829 94 0.015
regulation of cytoskeleton organization GO:0051493 89 0.015
neural precursor cell proliferation GO:0061351 75 0.015
jnk cascade GO:0007254 50 0.015
synapse assembly GO:0007416 143 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
response to ethanol GO:0045471 59 0.015
axon guidance GO:0007411 233 0.015
nucleobase containing compound catabolic process GO:0034655 165 0.015
proteolysis GO:0006508 192 0.015
regulation of multicellular organism growth GO:0040014 40 0.015
gene silencing GO:0016458 138 0.014
phosphatidylinositol mediated signaling GO:0048015 4 0.014
positive regulation of cell motility GO:2000147 3 0.014
organophosphate catabolic process GO:0046434 112 0.014
single organism carbohydrate metabolic process GO:0044723 72 0.014
defense response to other organism GO:0098542 225 0.014
myotube cell development GO:0014904 3 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
histone acetylation GO:0016573 38 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.014
heart development GO:0007507 82 0.014
mitochondrion organization GO:0007005 65 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
forebrain development GO:0030900 2 0.013
cell growth GO:0016049 108 0.013
organelle fission GO:0048285 340 0.013
mitotic cell cycle checkpoint GO:0007093 88 0.013
positive regulation of organelle organization GO:0010638 65 0.013
amide biosynthetic process GO:0043604 42 0.013
neuron recognition GO:0008038 101 0.013
regulation of sister chromatid cohesion GO:0007063 2 0.013
histone h4 k16 acetylation GO:0043984 4 0.013
tissue homeostasis GO:0001894 36 0.013
epithelium migration GO:0090132 148 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
imaginal disc derived leg morphogenesis GO:0007480 80 0.013
positive regulation of developmental growth GO:0048639 62 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
organic hydroxy compound metabolic process GO:1901615 83 0.012
muscle structure development GO:0061061 224 0.012
regulation of purine nucleotide catabolic process GO:0033121 48 0.012
insulin receptor signaling pathway GO:0008286 25 0.012
peptidyl lysine modification GO:0018205 57 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
canonical wnt signaling pathway GO:0060070 21 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
response to abiotic stimulus GO:0009628 341 0.012
internal peptidyl lysine acetylation GO:0018393 38 0.012
response to wounding GO:0009611 94 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
regulation of protein phosphorylation GO:0001932 64 0.012
embryonic axis specification GO:0000578 107 0.012
peptidyl lysine acetylation GO:0018394 39 0.012
regulation of purine nucleotide metabolic process GO:1900542 62 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
imaginal disc growth GO:0007446 37 0.011
anion homeostasis GO:0055081 3 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
chemosensory behavior GO:0007635 106 0.011
defense response GO:0006952 300 0.011
positive regulation of cell death GO:0010942 69 0.011
regulation of stress activated mapk cascade GO:0032872 41 0.011
response to radiation GO:0009314 155 0.011
negative regulation of cell development GO:0010721 62 0.011
regulation of rho gtpase activity GO:0032319 20 0.011
negative regulation of gene expression epigenetic GO:0045814 77 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.011
positive regulation of cell development GO:0010720 61 0.011
oocyte maturation GO:0001556 3 0.011
cell matrix adhesion GO:0007160 6 0.011
regulation of neural precursor cell proliferation GO:2000177 35 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 15 0.011
long term memory GO:0007616 62 0.011
protein phosphorylation GO:0006468 169 0.011
regulation of secretion GO:0051046 44 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
glial cell differentiation GO:0010001 35 0.011
stress activated protein kinase signaling cascade GO:0031098 55 0.011
negative regulation of developmental growth GO:0048640 64 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
protein complex biogenesis GO:0070271 201 0.011
protein localization GO:0008104 284 0.011
Human
extrinsic apoptotic signaling pathway GO:0097191 1 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.010
neurological system process GO:0050877 358 0.010
g2 m transition of mitotic cell cycle GO:0000086 19 0.010
chemical homeostasis GO:0048878 92 0.010
stem cell differentiation GO:0048863 117 0.010
epidermal growth factor receptor signaling pathway GO:0007173 58 0.010
cell division GO:0051301 248 0.010

Pez disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
cancer DOID:162 0 0.036
disease of cellular proliferation DOID:14566 0 0.036
organ system cancer DOID:0050686 0 0.036
musculoskeletal system disease DOID:17 0 0.013