Drosophila melanogaster

68 known processes

borr (Dmel_CG4454)

borealin-related

(Aliases: dBor,Bor,Dmel\CG4454,Borr,CG4454)

borr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic spindle organization GO:0007052 220 0.837
spindle organization GO:0007051 253 0.570
regulation of organelle organization GO:0033043 196 0.464
regulation of protein complex disassembly GO:0043244 29 0.420
sister chromatid segregation GO:0000819 92 0.414
Human
chromosome organization GO:0051276 360 0.390
mitotic cytokinesis GO:0000281 50 0.386
regulation of cell cycle phase transition GO:1901987 130 0.386
cell cycle phase transition GO:0044770 140 0.376
mitotic cell cycle checkpoint GO:0007093 88 0.372
regulation of protein depolymerization GO:1901879 27 0.369
regulation of microtubule cytoskeleton organization GO:0070507 41 0.367
regulation of mitotic cell cycle GO:0007346 190 0.354
chromatin organization GO:0006325 207 0.325
modification dependent macromolecule catabolic process GO:0043632 79 0.323
regulation of mitosis GO:0007088 56 0.316
mitotic sister chromatid segregation GO:0000070 87 0.293
Human
regulation of spindle organization GO:0090224 17 0.272
regulation of cell cycle process GO:0010564 181 0.265
cellular macromolecule catabolic process GO:0044265 136 0.265
regulation of cellular protein metabolic process GO:0032268 243 0.255
negative regulation of cellular metabolic process GO:0031324 382 0.252
negative regulation of cell cycle phase transition GO:1901988 103 0.241
regulation of mitotic cell cycle phase transition GO:1901990 130 0.214
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.205
macromolecule catabolic process GO:0009057 161 0.204
regulation of cell cycle GO:0051726 291 0.202
regulation of mitotic sister chromatid separation GO:0010965 28 0.194
negative regulation of gene expression GO:0010629 387 0.179
regulation of mitotic sister chromatid segregation GO:0033047 28 0.176
proteolysis GO:0006508 192 0.175
cytoskeleton dependent cytokinesis GO:0061640 81 0.174
catabolic process GO:0009056 409 0.172
regulation of chromosome organization GO:0033044 64 0.167
centrosome duplication GO:0051298 121 0.164
centrosome cycle GO:0007098 137 0.159
metaphase anaphase transition of cell cycle GO:0044784 28 0.155
negative regulation of mitotic cell cycle GO:0045930 109 0.149
spindle elongation GO:0051231 83 0.143
mitotic spindle elongation GO:0000022 81 0.142
cellular protein modification process GO:0006464 438 0.132
nuclear import GO:0051170 51 0.132
negative regulation of cytoskeleton organization GO:0051494 30 0.127
mitotic sister chromatid separation GO:0051306 30 0.125
regulation of cell division GO:0051302 72 0.125
establishment of spindle orientation GO:0051294 18 0.121
negative regulation of chromosome segregation GO:0051985 14 0.114
negative regulation of cell cycle GO:0045786 116 0.113
mitotic dna integrity checkpoint GO:0044774 75 0.112
regulation of cellular catabolic process GO:0031329 157 0.107
chromosome segregation GO:0007059 157 0.106
Human
protein catabolic process GO:0030163 101 0.090
regulation of cytoskeleton organization GO:0051493 89 0.088
organelle assembly GO:0070925 198 0.087
chromosome localization GO:0050000 20 0.087
Human
negative regulation of cell cycle process GO:0010948 109 0.086
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.084
appendage morphogenesis GO:0035107 397 0.082
mitotic nuclear division GO:0007067 213 0.081
mitotic cell cycle phase transition GO:0044772 138 0.080
regulation of protein metabolic process GO:0051246 256 0.079
negative regulation of organelle organization GO:0010639 56 0.079
cellular protein complex disassembly GO:0043624 35 0.079
protein modification by small protein conjugation or removal GO:0070647 106 0.077
phosphorylation GO:0016310 294 0.076
regulation of microtubule based process GO:0032886 49 0.072
proteasomal protein catabolic process GO:0010498 59 0.071
regulation of catalytic activity GO:0050790 185 0.070
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.069
regulation of protein modification process GO:0031399 112 0.066
negative regulation of protein depolymerization GO:1901880 23 0.066
negative regulation of protein complex disassembly GO:0043242 23 0.066
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.065
negative regulation of cellular biosynthetic process GO:0031327 277 0.064
mitotic g2 m transition checkpoint GO:0044818 70 0.064
epithelial cell differentiation GO:0030855 322 0.064
macromolecular complex disassembly GO:0032984 37 0.063
regulation of cell development GO:0060284 215 0.062
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.061
regulation of protein catabolic process GO:0042176 55 0.061
regulation of cell differentiation GO:0045595 302 0.060
macromolecular complex assembly GO:0065003 256 0.060
appendage development GO:0048736 401 0.058
imaginal disc derived appendage development GO:0048737 399 0.058
centrosome organization GO:0051297 163 0.057
protein modification by small protein conjugation GO:0032446 79 0.057
cellular macromolecular complex assembly GO:0034622 153 0.056
wing disc morphogenesis GO:0007472 344 0.055
regulation of sister chromatid segregation GO:0033045 28 0.055
cytokinesis GO:0000910 90 0.055
microtubule depolymerization GO:0007019 25 0.054
post embryonic appendage morphogenesis GO:0035120 385 0.054
ubiquitin dependent protein catabolic process GO:0006511 78 0.054
regulation of multicellular organismal development GO:2000026 414 0.053
actin cytoskeleton organization GO:0030036 206 0.053
actin filament organization GO:0007015 126 0.053
cellular macromolecule localization GO:0070727 220 0.053
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.051
cell division GO:0051301 248 0.050
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.050
regulation of proteasomal protein catabolic process GO:0061136 39 0.048
spindle assembly GO:0051225 80 0.047
immune system process GO:0002376 347 0.046
regulation of catabolic process GO:0009894 170 0.046
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.046
cellular response to abiotic stimulus GO:0071214 58 0.046
cellular component assembly involved in morphogenesis GO:0010927 151 0.046
single organism cellular localization GO:1902580 180 0.045
organic substance catabolic process GO:1901575 308 0.045
cellular protein complex assembly GO:0043623 71 0.045
regulation of cellular component biogenesis GO:0044087 201 0.044
cellular catabolic process GO:0044248 372 0.043
modification dependent protein catabolic process GO:0019941 78 0.042
protein transport GO:0015031 155 0.041
regulation of nervous system development GO:0051960 248 0.040
cell cycle checkpoint GO:0000075 95 0.040
regulation of phosphorus metabolic process GO:0051174 210 0.039
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.038
negative regulation of cellular component organization GO:0051129 108 0.038
eye morphogenesis GO:0048592 260 0.037
chromatin modification GO:0016568 147 0.037
histone modification GO:0016570 106 0.036
regulation of cell death GO:0010941 173 0.035
positive regulation of protein metabolic process GO:0051247 128 0.035
regulation of molecular function GO:0065009 217 0.035
embryo development ending in birth or egg hatching GO:0009792 152 0.034
body morphogenesis GO:0010171 2 0.034
reproductive system development GO:0061458 74 0.034
protein complex assembly GO:0006461 200 0.033
regulation of neurogenesis GO:0050767 158 0.033
protein phosphorylation GO:0006468 169 0.032
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.032
apoptotic process GO:0006915 159 0.032
dna damage checkpoint GO:0000077 78 0.032
positive regulation of molecular function GO:0044093 136 0.032
imaginal disc derived appendage morphogenesis GO:0035114 395 0.032
microtubule organizing center organization GO:0031023 168 0.032
regulation of microtubule depolymerization GO:0031114 24 0.032
protein complex disassembly GO:0043241 36 0.031
positive regulation of phosphate metabolic process GO:0045937 139 0.031
protein modification process GO:0036211 438 0.031
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.030
posttranscriptional regulation of gene expression GO:0010608 145 0.030
neuromuscular junction development GO:0007528 149 0.030
regulation of proteolysis GO:0030162 87 0.029
dna metabolic process GO:0006259 227 0.029
spindle assembly involved in mitosis GO:0090307 50 0.029
positive regulation of catabolic process GO:0009896 105 0.029
homeostatic process GO:0042592 199 0.027
dna integrity checkpoint GO:0031570 81 0.027
mitotic dna damage checkpoint GO:0044773 74 0.027
cellular protein localization GO:0034613 160 0.027
spindle midzone assembly GO:0051255 4 0.026
positive regulation of cellular protein metabolic process GO:0032270 118 0.026
protein localization GO:0008104 284 0.025
regulation of phosphate metabolic process GO:0019220 210 0.025
cellular protein catabolic process GO:0044257 83 0.024
negative regulation of rna metabolic process GO:0051253 251 0.024
regulation of cellular protein catabolic process GO:1903362 44 0.024
establishment or maintenance of cell polarity GO:0007163 167 0.024
ovarian follicle cell development GO:0030707 248 0.023
regulation of wnt signaling pathway GO:0030111 68 0.023
regulation of protein localization GO:0032880 76 0.023
protein ubiquitination GO:0016567 70 0.022
actin filament based process GO:0030029 220 0.022
negative regulation of signaling GO:0023057 219 0.022
cellularization GO:0007349 90 0.022
anatomical structure homeostasis GO:0060249 97 0.022
response to organic substance GO:0010033 284 0.021
negative regulation of chromosome organization GO:2001251 19 0.021
mitotic spindle midzone assembly GO:0051256 1 0.021
negative regulation of protein metabolic process GO:0051248 85 0.021
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.020
regulation of cell cycle g1 s phase transition GO:1902806 23 0.020
female meiosis i GO:0007144 8 0.020
positive regulation of cell cycle GO:0045787 43 0.020
endocytosis GO:0006897 310 0.020
positive regulation of nucleic acid templated transcription GO:1903508 266 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
protein depolymerization GO:0051261 31 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
wnt signaling pathway GO:0016055 98 0.019
regulation of chromosome segregation GO:0051983 32 0.019
cell death GO:0008219 279 0.019
phagocytosis GO:0006909 215 0.019
limb morphogenesis GO:0035108 1 0.019
protein localization to organelle GO:0033365 82 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
regulation of nuclear division GO:0051783 58 0.018
establishment of spindle localization GO:0051293 22 0.018
intracellular signal transduction GO:0035556 300 0.018
negative regulation of programmed cell death GO:0043069 72 0.018
negative regulation of phosphate metabolic process GO:0045936 45 0.018
intracellular protein transport GO:0006886 104 0.018
negative regulation of signal transduction GO:0009968 206 0.018
regulation of cell proliferation GO:0042127 163 0.018
establishment of localization in cell GO:0051649 402 0.018
Human
compound eye development GO:0048749 307 0.017
heterocycle catabolic process GO:0046700 166 0.017
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.017
spindle localization GO:0051653 22 0.017
single organism catabolic process GO:0044712 228 0.017
chromosome separation GO:0051304 42 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
g1 s transition of mitotic cell cycle GO:0000082 31 0.016
negative regulation of response to stimulus GO:0048585 258 0.016
blastoderm segmentation GO:0007350 159 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
cell fate determination GO:0001709 91 0.016
organonitrogen compound metabolic process GO:1901564 318 0.016
negative regulation of protein catabolic process GO:0042177 17 0.016
cellular component disassembly GO:0022411 46 0.015
regulation of programmed cell death GO:0043067 152 0.015
organelle fission GO:0048285 340 0.015
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.015
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.015
endomembrane system organization GO:0010256 119 0.015
cellular response to organic substance GO:0071310 132 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.014
protein import into nucleus GO:0006606 51 0.014
negative regulation of cell division GO:0051782 17 0.014
meiotic chromosome segregation GO:0045132 59 0.014
negative regulation of apoptotic process GO:0043066 63 0.014
regulation of hydrolase activity GO:0051336 97 0.014
regionalization GO:0003002 416 0.014
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 17 0.014
centrosome separation GO:0051299 20 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.013
regulation of transport GO:0051049 181 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
negative regulation of proteolysis GO:0045861 31 0.013
positive regulation of cell communication GO:0010647 250 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
mitotic spindle assembly checkpoint GO:0007094 11 0.013
positive regulation of binding GO:0051099 4 0.013
protein maturation GO:0051604 71 0.013
mitotic spindle checkpoint GO:0071174 11 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
negative regulation of meiotic cell cycle GO:0051447 2 0.013
regulation of localization GO:0032879 275 0.013
single organism nuclear import GO:1902593 51 0.013
regulation of rac gtpase activity GO:0032314 1 0.013
single organism membrane organization GO:0044802 93 0.012
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
protein import GO:0017038 55 0.012
nuclear transport GO:0051169 72 0.012
organic substance transport GO:0071702 257 0.012
regulation of cytoplasmic transport GO:1903649 47 0.012
reproductive structure development GO:0048608 74 0.012
positive regulation of chromatin silencing GO:0031937 16 0.012
rna processing GO:0006396 147 0.011
compound eye morphogenesis GO:0001745 249 0.011
mitochondrial membrane organization GO:0007006 3 0.011
regulation of cellular localization GO:0060341 136 0.011
sensory organ morphogenesis GO:0090596 260 0.011
cell proliferation GO:0008283 299 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
positive regulation of gene expression GO:0010628 290 0.011
negative regulation of cell proliferation GO:0008285 69 0.011
negative regulation of catabolic process GO:0009895 36 0.011
gonad development GO:0008406 50 0.011
positive regulation of organelle organization GO:0010638 65 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
protein complex biogenesis GO:0070271 201 0.010
cell growth GO:0016049 108 0.010
negative regulation of developmental process GO:0051093 201 0.010
mitotic g2 dna damage checkpoint GO:0007095 69 0.010
intracellular transport GO:0046907 228 0.010
histone methylation GO:0016571 40 0.010
larval development GO:0002164 104 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
regulation of intracellular protein transport GO:0033157 46 0.010
negative regulation of notch signaling pathway GO:0045746 41 0.010
organelle localization GO:0051640 148 0.010
Human

borr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016