Drosophila melanogaster

16 known processes

Akh (Dmel_CG1171)

Adipokinetic hormone

(Aliases: Dmel\CG1171,akh,dAkh,CG1171,Drm-AKH,Hrth,AKH)

Akh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic substance transport GO:0071702 257 0.049
imaginal disc derived wing morphogenesis GO:0007476 337 0.043
oxoacid metabolic process GO:0043436 103 0.041
vesicle mediated transport GO:0016192 381 0.038
wing disc morphogenesis GO:0007472 344 0.038
triglyceride catabolic process GO:0019433 3 0.037
imaginal disc derived appendage morphogenesis GO:0035114 395 0.037
neuropeptide signaling pathway GO:0007218 45 0.037
carboxylic acid metabolic process GO:0019752 92 0.037
appendage morphogenesis GO:0035107 397 0.035
endocytosis GO:0006897 310 0.035
phagocytosis GO:0006909 215 0.034
adult behavior GO:0030534 137 0.032
homeostatic process GO:0042592 199 0.032
organic acid metabolic process GO:0006082 103 0.032
response to alcohol GO:0097305 95 0.031
neurological system process GO:0050877 358 0.031
catabolic process GO:0009056 409 0.031
organic substance catabolic process GO:1901575 308 0.031
appendage development GO:0048736 401 0.030
single organism catabolic process GO:0044712 228 0.030
acylglycerol catabolic process GO:0046464 3 0.030
post embryonic appendage morphogenesis GO:0035120 385 0.029
small molecule metabolic process GO:0044281 305 0.028
single organism behavior GO:0044708 391 0.028
chemical homeostasis GO:0048878 92 0.027
lipid catabolic process GO:0016042 21 0.027
response to abiotic stimulus GO:0009628 341 0.026
regulation of localization GO:0032879 275 0.025
imaginal disc derived appendage development GO:0048737 399 0.025
positive regulation of lipid storage GO:0010884 4 0.025
behavioral response to ethanol GO:0048149 49 0.025
body morphogenesis GO:0010171 2 0.024
organonitrogen compound metabolic process GO:1901564 318 0.024
cellular catabolic process GO:0044248 372 0.023
response to lipopolysaccharide GO:0032496 4 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
negative regulation of signal transduction GO:0009968 206 0.022
regulation of cell cycle GO:0051726 291 0.022
regulation of cellular amine metabolic process GO:0033238 3 0.022
response to organic substance GO:0010033 284 0.022
lipid metabolic process GO:0006629 121 0.022
cell death GO:0008219 279 0.022
response to nutrient levels GO:0031667 114 0.022
mating GO:0007618 120 0.022
immune system process GO:0002376 347 0.021
regulation of multicellular organismal development GO:2000026 414 0.021
circadian rhythm GO:0007623 105 0.021
protein modification process GO:0036211 438 0.021
response to extracellular stimulus GO:0009991 116 0.020
positive regulation of signal transduction GO:0009967 223 0.020
cellular protein localization GO:0034613 160 0.020
forebrain development GO:0030900 2 0.020
sterol homeostasis GO:0055092 4 0.020
programmed cell death GO:0012501 257 0.020
regionalization GO:0003002 416 0.020
positive regulation of cell communication GO:0010647 250 0.020
positive regulation of signaling GO:0023056 243 0.020
positive regulation of response to stimulus GO:0048584 323 0.020
maintenance of location GO:0051235 73 0.019
salivary gland development GO:0007431 162 0.019
determination of adult lifespan GO:0008340 137 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.019
multicellular organismal aging GO:0010259 140 0.019
exocrine system development GO:0035272 162 0.019
cellular lipid metabolic process GO:0044255 83 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
negative regulation of gene expression GO:0010629 387 0.019
negative regulation of cellular metabolic process GO:0031324 382 0.019
salivary gland morphogenesis GO:0007435 145 0.019
phosphatidic acid metabolic process GO:0046473 1 0.019
response to oxygen containing compound GO:1901700 200 0.018
protein complex biogenesis GO:0070271 201 0.018
single organism biosynthetic process GO:0044711 206 0.018
cellular protein modification process GO:0006464 438 0.018
intracellular transport GO:0046907 228 0.018
mating behavior GO:0007617 106 0.018
establishment of localization in cell GO:0051649 402 0.018
telencephalon development GO:0021537 2 0.018
regulation of cell differentiation GO:0045595 302 0.018
regulation of lipid storage GO:0010883 22 0.017
negative regulation of cell communication GO:0010648 223 0.017
death GO:0016265 284 0.017
positive regulation of cell migration GO:0030335 2 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
rhythmic process GO:0048511 106 0.017
camera type eye development GO:0043010 4 0.017
macromolecular complex assembly GO:0065003 256 0.017
protein localization GO:0008104 284 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
regulation of organelle organization GO:0033043 196 0.017
cellular response to ethanol GO:0071361 4 0.017
developmental programmed cell death GO:0010623 138 0.017
cellular response to chemical stimulus GO:0070887 199 0.016
cellular homeostasis GO:0019725 80 0.016
sensory perception GO:0007600 196 0.016
taxis GO:0042330 304 0.016
cellular amine metabolic process GO:0044106 12 0.016
regulation of cell death GO:0010941 173 0.016
actin cytoskeleton organization GO:0030036 206 0.016
lipid localization GO:0010876 54 0.016
response to other organism GO:0051707 293 0.016
lipid biosynthetic process GO:0008610 46 0.015
negative regulation of signaling GO:0023057 219 0.015
single organism intracellular transport GO:1902582 207 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
lateral inhibition GO:0046331 206 0.015
triglyceride metabolic process GO:0006641 12 0.015
cellular ketone metabolic process GO:0042180 24 0.015
ethanolamine containing compound metabolic process GO:0042439 4 0.015
aging GO:0007568 143 0.015
positive regulation of cell motility GO:2000147 3 0.015
response to light stimulus GO:0009416 124 0.015
response to high light intensity GO:0009644 1 0.015
detection of stimulus GO:0051606 156 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
response to starvation GO:0042594 97 0.014
protein complex assembly GO:0006461 200 0.014
tissue death GO:0016271 102 0.014
negative regulation of developmental process GO:0051093 201 0.014
eye development GO:0001654 323 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.014
positive regulation of biosynthetic process GO:0009891 316 0.014
compound eye morphogenesis GO:0001745 249 0.014
central nervous system development GO:0007417 201 0.014
cell proliferation GO:0008283 299 0.014
cellular response to biotic stimulus GO:0071216 4 0.014
organophosphate metabolic process GO:0019637 195 0.014
establishment of protein localization GO:0045184 163 0.014
pigmentation GO:0043473 75 0.014
response to radiation GO:0009314 155 0.014
defense response GO:0006952 300 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
connective tissue development GO:0061448 3 0.014
monocarboxylic acid transport GO:0015718 3 0.014
androgen metabolic process GO:0008209 1 0.013
detection of chemical stimulus GO:0009593 93 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
wnt signaling pathway GO:0016055 98 0.013
gland development GO:0048732 191 0.013
epithelial cell differentiation GO:0030855 322 0.013
response to ethanol GO:0045471 59 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
heterocycle catabolic process GO:0046700 166 0.013
glycerolipid catabolic process GO:0046503 3 0.013
chemosensory behavior GO:0007635 106 0.013
acylglycerol biosynthetic process GO:0046463 2 0.013
regulation of catabolic process GO:0009894 170 0.013
cellular response to light intensity GO:0071484 1 0.013
triglyceride biosynthetic process GO:0019432 2 0.013
response to external biotic stimulus GO:0043207 293 0.013
response to temperature stimulus GO:0009266 106 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
amine metabolic process GO:0009308 12 0.013
actin filament based process GO:0030029 220 0.013
cellular response to organic substance GO:0071310 132 0.013
cellular macromolecule localization GO:0070727 220 0.013
eye morphogenesis GO:0048592 260 0.013
organelle fission GO:0048285 340 0.013
axis specification GO:0009798 167 0.013
negative regulation of cell death GO:0060548 81 0.013
ion transport GO:0006811 145 0.013
organelle assembly GO:0070925 198 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
response to nitrogen compound GO:1901698 90 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
nuclear division GO:0000280 332 0.012
very long chain fatty acid metabolic process GO:0000038 4 0.012
pigment metabolic process GO:0042440 84 0.012
neutral lipid biosynthetic process GO:0046460 2 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
segmentation GO:0035282 207 0.012
synapse assembly GO:0007416 143 0.012
pigment biosynthetic process GO:0046148 36 0.012
sensory perception of smell GO:0007608 80 0.012
intracellular signal transduction GO:0035556 300 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
developmental pigmentation GO:0048066 68 0.012
oxidation reduction process GO:0055114 123 0.012
protein transport GO:0015031 155 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
cell cycle phase transition GO:0044770 140 0.012
ras protein signal transduction GO:0007265 88 0.012
glycerolipid metabolic process GO:0046486 34 0.012
smoothened signaling pathway GO:0007224 49 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
sensory organ morphogenesis GO:0090596 260 0.012
regulation of programmed cell death GO:0043067 152 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
compound eye development GO:0048749 307 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
autophagic cell death GO:0048102 83 0.012
histolysis GO:0007559 102 0.012
response to biotic stimulus GO:0009607 294 0.012
response to organophosphorus GO:0046683 2 0.011
regulation of cell proliferation GO:0042127 163 0.011
multi organism behavior GO:0051705 175 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
long chain fatty acid metabolic process GO:0001676 3 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
regulation of molecular function GO:0065009 217 0.011
developmental growth GO:0048589 280 0.011
chemotaxis GO:0006935 249 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
secondary metabolic process GO:0019748 75 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
retina development in camera type eye GO:0060041 4 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
regulation of cell development GO:0060284 215 0.011
chromosome organization GO:0051276 360 0.011
cell motility GO:0048870 251 0.011
tube morphogenesis GO:0035239 191 0.011
open tracheal system development GO:0007424 204 0.011
mitotic nuclear division GO:0007067 213 0.011
rna processing GO:0006396 147 0.011
defense response to other organism GO:0098542 225 0.011
sensory perception of chemical stimulus GO:0007606 116 0.011
axon guidance GO:0007411 233 0.011
gland morphogenesis GO:0022612 145 0.011
regulation of protein metabolic process GO:0051246 256 0.011
apoptotic process GO:0006915 159 0.011
regulation of response to stress GO:0080134 200 0.011
response to endogenous stimulus GO:0009719 119 0.011
eye pigment biosynthetic process GO:0006726 32 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
regulation of sequestering of triglyceride GO:0010889 3 0.010
transmembrane transport GO:0055085 139 0.010
synaptic transmission GO:0007268 288 0.010
organic hydroxy compound metabolic process GO:1901615 83 0.010
regulation of catalytic activity GO:0050790 185 0.010
regulation of transport GO:0051049 181 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
positive regulation of developmental process GO:0051094 143 0.010
lipid homeostasis GO:0055088 33 0.010
male courtship behavior GO:0008049 63 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.010
tube development GO:0035295 244 0.010
regulation of phosphorus metabolic process GO:0051174 210 0.010
acetaldehyde metabolic process GO:0006117 5 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010
cell recognition GO:0008037 102 0.010
cellular response to nitrogen compound GO:1901699 51 0.010
spindle organization GO:0007051 253 0.010
cholesterol homeostasis GO:0042632 3 0.010
neuromuscular junction development GO:0007528 149 0.010
phosphorylation GO:0016310 294 0.010

Akh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.019
inherited metabolic disorder DOID:655 0 0.018
disease of metabolism DOID:0014667 0 0.018
carbohydrate metabolism disease DOID:0050013 0 0.012
type 2 diabetes mellitus DOID:9352 0 0.012
diabetes mellitus DOID:9351 0 0.012
acquired metabolic disease DOID:0060158 0 0.012
glucose metabolism disease DOID:4194 0 0.012
sensory system disease DOID:0050155 0 0.011