Drosophila melanogaster

14 known processes

Kap-alpha1 (Dmel_CG8548)

karyopherin alpha1

(Aliases: imp alpha1,IMPalpha1,Dalpha1,CG8548,impalpha1,Dmel\CG8548,anon-WO0118547.276,Kpna1,Kap alpha1)

Kap-alpha1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular biosynthetic process GO:0031328 316 0.168
Mouse
defense response GO:0006952 300 0.156
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.153
Mouse
regulation of intracellular signal transduction GO:1902531 236 0.140
establishment of protein localization GO:0045184 163 0.112
Mouse Rat
intracellular transport GO:0046907 228 0.073
Mouse Rat
intracellular signal transduction GO:0035556 300 0.073
protein modification by small protein conjugation or removal GO:0070647 106 0.072
protein modification process GO:0036211 438 0.064
defense response to bacterium GO:0042742 178 0.059
single organism intracellular transport GO:1902582 207 0.055
Mouse Rat
regulation of localization GO:0032879 275 0.051
Rat
protein ubiquitination GO:0016567 70 0.050
regulation of cell cycle GO:0051726 291 0.049
eye development GO:0001654 323 0.049
cellular protein modification process GO:0006464 438 0.048
positive regulation of catalytic activity GO:0043085 118 0.047
defense response to other organism GO:0098542 225 0.045
organic substance transport GO:0071702 257 0.045
Mouse Rat
establishment of localization in cell GO:0051649 402 0.042
Mouse Rat
eye morphogenesis GO:0048592 260 0.040
protein localization GO:0008104 284 0.038
Mouse Rat
regulation of growth GO:0040008 233 0.037
regulation of meiosis GO:0040020 3 0.036
protein modification by small protein conjugation GO:0032446 79 0.035
embryo development ending in birth or egg hatching GO:0009792 152 0.035
nucleoside triphosphate metabolic process GO:0009141 120 0.034
compound eye morphogenesis GO:0001745 249 0.033
cytoplasmic transport GO:0016482 130 0.033
Mouse Rat
larval development GO:0002164 104 0.033
positive regulation of rna biosynthetic process GO:1902680 266 0.031
Mouse
phosphorylation GO:0016310 294 0.031
positive regulation of epidermal growth factor activated receptor activity GO:0045741 1 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.030
Mouse
small molecule metabolic process GO:0044281 305 0.030
death GO:0016265 284 0.028
positive regulation of signaling GO:0023056 243 0.028
response to external biotic stimulus GO:0043207 293 0.028
reproductive system development GO:0061458 74 0.025
regulation of phosphorus metabolic process GO:0051174 210 0.024
ribonucleoside metabolic process GO:0009119 127 0.024
posttranscriptional regulation of gene expression GO:0010608 145 0.023
vesicle mediated transport GO:0016192 381 0.023
purine nucleoside metabolic process GO:0042278 127 0.022
sensory organ morphogenesis GO:0090596 260 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
intracellular protein transport GO:0006886 104 0.022
Mouse Rat
macromolecule catabolic process GO:0009057 161 0.020
nucleoside catabolic process GO:0009164 112 0.020
positive regulation of rna metabolic process GO:0051254 271 0.020
Mouse
purine ribonucleotide catabolic process GO:0009154 109 0.020
regulation of cell division GO:0051302 72 0.020
cell death GO:0008219 279 0.019
positive regulation of biosynthetic process GO:0009891 316 0.018
Mouse
regulation of protein modification process GO:0031399 112 0.018
ras protein signal transduction GO:0007265 88 0.018
aromatic compound catabolic process GO:0019439 166 0.018
establishment of protein localization to organelle GO:0072594 62 0.017
Mouse Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.017
Mouse
imaginal disc derived appendage development GO:0048737 399 0.017
protein localization to organelle GO:0033365 82 0.017
Mouse Rat
cellular macromolecule catabolic process GO:0044265 136 0.017
ribonucleoprotein complex disassembly GO:0032988 1 0.017
regulation of gene expression epigenetic GO:0040029 128 0.017
protein transport GO:0015031 155 0.017
Mouse Rat
regulation of mapk cascade GO:0043408 92 0.016
defense response to gram negative bacterium GO:0050829 94 0.016
regulation of ras protein signal transduction GO:0046578 93 0.016
regulation of protein metabolic process GO:0051246 256 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
Mouse
regulation of cellular component biogenesis GO:0044087 201 0.016
modification dependent protein catabolic process GO:0019941 78 0.015
catabolic process GO:0009056 409 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
positive regulation of cell communication GO:0010647 250 0.015
negative regulation of phosphorylation GO:0042326 35 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
Mouse Rat
regulation of transport GO:0051049 181 0.014
Rat
regulation of nucleocytoplasmic transport GO:0046822 35 0.014
Rat
organic substance catabolic process GO:1901575 308 0.014
regulation of protein localization GO:0032880 76 0.014
Rat
developmental programmed cell death GO:0010623 138 0.014
regulation of protein import into nucleus GO:0042306 28 0.014
Rat
small gtpase mediated signal transduction GO:0007264 88 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
regulation of programmed cell death GO:0043067 152 0.014
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
Mouse
nucleoside phosphate catabolic process GO:1901292 110 0.013
response to other organism GO:0051707 293 0.013
organonitrogen compound metabolic process GO:1901564 318 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
positive regulation of transcription dna templated GO:0045893 266 0.012
Mouse
cellular protein catabolic process GO:0044257 83 0.012
compound eye development GO:0048749 307 0.012
positive regulation of signal transduction GO:0009967 223 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
appendage morphogenesis GO:0035107 397 0.011
cellular protein localization GO:0034613 160 0.011
Mouse Rat
negative regulation of cellular metabolic process GO:0031324 382 0.011
cell cycle checkpoint GO:0000075 95 0.011
mapk cascade GO:0000165 107 0.011
regulation of cellular localization GO:0060341 136 0.011
Rat
regulation of phosphorylation GO:0042325 147 0.011
response to biotic stimulus GO:0009607 294 0.011
negative regulation of cell death GO:0060548 81 0.011
protein targeting GO:0006605 64 0.010
Mouse Rat
regulation of intracellular transport GO:0032386 64 0.010
Rat
kidney development GO:0001822 3 0.010
regulation of locomotion GO:0040012 42 0.010
oxoacid metabolic process GO:0043436 103 0.010
regulation of cell cycle process GO:0010564 181 0.010

Kap-alpha1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.035