Drosophila melanogaster

70 known processes

asl (Dmel_CG2919)

asterless

(Aliases: CG2919,Dmel\CG2919,mecD,sdu,Asl)

asl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 151 1.000
meiotic cell cycle GO:0051321 171 1.000
organelle fission GO:0048285 340 0.999
nuclear division GO:0000280 332 0.999
sister chromatid segregation GO:0000819 92 0.998
male meiosis GO:0007140 52 0.997
centrosome cycle GO:0007098 137 0.996
organelle assembly GO:0070925 198 0.983
mitotic sister chromatid segregation GO:0000070 87 0.981
spindle organization GO:0007051 253 0.975
microtubule organizing center organization GO:0031023 168 0.966
centrosome duplication GO:0051298 121 0.961
spindle assembly involved in mitosis GO:0090307 50 0.955
mitotic spindle organization GO:0007052 220 0.940
centrosome separation GO:0051299 20 0.930
meiotic cell cycle process GO:1903046 132 0.926
meiotic chromosome segregation GO:0045132 59 0.922
spindle assembly GO:0051225 80 0.922
centriole centriole cohesion GO:0010457 5 0.920
chromosome segregation GO:0007059 157 0.920
spindle assembly involved in female meiosis GO:0007056 14 0.890
centrosome organization GO:0051297 163 0.879
male meiosis cytokinesis GO:0007112 26 0.868
meiotic sister chromatid segregation GO:0045144 6 0.824
mitotic spindle elongation GO:0000022 81 0.797
mitotic centrosome separation GO:0007100 8 0.789
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.788
regulation of microtubule cytoskeleton organization GO:0070507 41 0.783
spindle assembly involved in meiosis GO:0090306 20 0.763
regulation of chromosome segregation GO:0051983 32 0.761
macromolecular complex disassembly GO:0032984 37 0.720
nuclear migration GO:0007097 20 0.683
regulation of mitotic spindle organization GO:0060236 9 0.655
centriole replication GO:0007099 24 0.641
regulation of spindle elongation GO:0032887 1 0.601
somatic stem cell division GO:0048103 37 0.599
spindle stabilization GO:0043146 14 0.591
cellular component disassembly GO:0022411 46 0.576
organelle localization GO:0051640 148 0.563
mitotic spindle stabilization GO:0043148 6 0.563
regulation of microtubule based process GO:0032886 49 0.538
mitotic sister chromatid separation GO:0051306 30 0.504
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.474
meiosis i GO:0007127 59 0.458
microtubule anchoring GO:0034453 11 0.440
pronuclear migration GO:0035046 4 0.439
cell division GO:0051301 248 0.421
female meiotic division GO:0007143 70 0.407
regulation of spindle organization GO:0090224 17 0.399
regulation of cytoskeleton organization GO:0051493 89 0.374
spindle assembly involved in female meiosis i GO:0007057 5 0.369
macromolecular complex assembly GO:0065003 256 0.352
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.339
regulation of organelle organization GO:0033043 196 0.327
single fertilization GO:0007338 24 0.316
negative regulation of cellular component organization GO:0051129 108 0.294
establishment of organelle localization GO:0051656 122 0.278
negative regulation of cytoskeleton organization GO:0051494 30 0.272
mitotic spindle checkpoint GO:0071174 11 0.241
meiotic spindle organization GO:0000212 36 0.240
centriole assembly GO:0098534 24 0.238
cytokinetic process GO:0032506 27 0.235
regulation of cell cycle process GO:0010564 181 0.232
stem cell division GO:0017145 69 0.227
establishment of nucleus localization GO:0040023 26 0.224
nucleus localization GO:0051647 34 0.212
regulation of cell cycle phase transition GO:1901987 130 0.212
mitotic cell cycle phase transition GO:0044772 138 0.209
reciprocal dna recombination GO:0035825 19 0.209
protein complex assembly GO:0006461 200 0.207
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.196
microtubule polymerization or depolymerization GO:0031109 39 0.196
mitotic metaphase plate congression GO:0007080 13 0.193
regulation of mitochondrial fusion GO:0010635 5 0.192
neuronal stem cell division GO:0036445 35 0.188
mitotic nuclear division GO:0007067 213 0.187
chromosome localization GO:0050000 20 0.186
negative regulation of mitotic sister chromatid segregation GO:0033048 13 0.184
regulation of protein complex disassembly GO:0043244 29 0.182
negative regulation of mitotic cell cycle GO:0045930 109 0.180
mitotic cell cycle embryonic GO:0045448 38 0.178
regulation of mitotic sister chromatid separation GO:0010965 28 0.178
cellular protein complex disassembly GO:0043624 35 0.177
meiotic cytokinesis GO:0033206 33 0.173
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.159
negative regulation of mitotic metaphase anaphase transition GO:0045841 13 0.158
macromolecule catabolic process GO:0009057 161 0.155
cilium morphogenesis GO:0060271 39 0.151
establishment of spindle orientation GO:0051294 18 0.149
regulation of cell division GO:0051302 72 0.149
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.146
cellular protein complex assembly GO:0043623 71 0.145
spindle checkpoint GO:0031577 11 0.142
establishment or maintenance of cell polarity GO:0007163 167 0.141
meiosis ii GO:0007135 23 0.141
establishment of localization in cell GO:0051649 402 0.141
attachment of spindle microtubules to kinetochore GO:0008608 5 0.136
ovarian fusome organization GO:0030723 11 0.134
cystoblast division GO:0007282 10 0.127
cilium organization GO:0044782 41 0.127
meiotic spindle midzone assembly GO:0051257 3 0.124
embryo development ending in birth or egg hatching GO:0009792 152 0.122
maintenance of location in cell GO:0051651 28 0.119
negative regulation of protein depolymerization GO:1901880 23 0.116
regulation of protein catabolic process GO:0042176 55 0.113
metaphase plate congression GO:0051310 19 0.112
cell cycle phase transition GO:0044770 140 0.109
negative regulation of chromosome segregation GO:0051985 14 0.109
protein localization GO:0008104 284 0.107
female meiosis chromosome segregation GO:0016321 33 0.106
regulation of mitotic sister chromatid segregation GO:0033047 28 0.106
cell proliferation GO:0008283 299 0.105
spindle assembly involved in male meiosis GO:0007053 5 0.103
contractile ring contraction GO:0036213 12 0.103
negative regulation of cell cycle GO:0045786 116 0.102
cytokinesis GO:0000910 90 0.100
spindle midzone assembly GO:0051255 4 0.099
regulation of mitotic cell cycle phase transition GO:1901990 130 0.095
protein complex disassembly GO:0043241 36 0.093
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.091
cellular protein localization GO:0034613 160 0.089
establishment of chromosome localization GO:0051303 20 0.087
regulation of protein depolymerization GO:1901879 27 0.087
cytoskeleton dependent cytokinesis GO:0061640 81 0.085
establishment of meiotic spindle orientation GO:0051296 2 0.084
asymmetric cell division GO:0008356 37 0.081
single organism cellular localization GO:1902580 180 0.080
maintenance of protein location in cell GO:0032507 26 0.077
microtubule depolymerization GO:0007019 25 0.076
protein complex biogenesis GO:0070271 201 0.076
mitotic cell cycle checkpoint GO:0007093 88 0.075
mitotic spindle assembly checkpoint GO:0007094 11 0.074
axoneme assembly GO:0035082 18 0.071
oocyte differentiation GO:0009994 145 0.070
regulation of mitosis GO:0007088 56 0.069
membrane disassembly GO:0030397 4 0.067
regulation of nuclear division GO:0051783 58 0.066
microtubule based movement GO:0007018 51 0.065
golgi localization GO:0051645 2 0.062
meiotic sister chromatid cohesion GO:0051177 6 0.062
regulation of cellular localization GO:0060341 136 0.060
intracellular transport GO:0046907 228 0.059
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 17 0.057
regulation of microtubule depolymerization GO:0031114 24 0.057
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.056
mitotic cytokinesis GO:0000281 50 0.055
microtubule polymerization GO:0046785 15 0.054
endomembrane system organization GO:0010256 119 0.054
microtubule bundle formation GO:0001578 27 0.054
asymmetric stem cell division GO:0098722 49 0.052
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.050
neural precursor cell proliferation GO:0061351 75 0.048
nuclear envelope organization GO:0006998 7 0.048
modification dependent macromolecule catabolic process GO:0043632 79 0.045
chromosome separation GO:0051304 42 0.045
negative regulation of cellular protein metabolic process GO:0032269 85 0.045
negative regulation of cell division GO:0051782 17 0.045
maintenance of protein location GO:0045185 28 0.044
regulation of cellular catabolic process GO:0031329 157 0.044
cellular macromolecular complex assembly GO:0034622 153 0.043
metaphase anaphase transition of cell cycle GO:0044784 28 0.043
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.042
kinetochore organization GO:0051383 9 0.041
negative regulation of protein complex disassembly GO:0043242 23 0.040
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.039
protein depolymerization GO:0051261 31 0.038
protein polymerization GO:0051258 42 0.037
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 13 0.037
regulation of proteolysis GO:0030162 87 0.037
asymmetric neuroblast division GO:0055059 33 0.036
regulation of mitotic cell cycle GO:0007346 190 0.035
oocyte development GO:0048599 124 0.034
establishment of cell polarity GO:0030010 40 0.034
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.033
protein localization to organelle GO:0033365 82 0.033
ubiquitin dependent protein catabolic process GO:0006511 78 0.033
maintenance of location GO:0051235 73 0.033
neuronal stem cell maintenance GO:0097150 4 0.032
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.032
establishment of mitotic spindle orientation GO:0000132 13 0.032
spindle elongation GO:0051231 83 0.031
cellular component assembly involved in morphogenesis GO:0010927 151 0.031
regulation of centrosome cycle GO:0046605 7 0.031
larval development GO:0002164 104 0.029
vesicle mediated transport GO:0016192 381 0.028
endocytosis GO:0006897 310 0.027
fertilization GO:0009566 26 0.027
meiotic chromosome separation GO:0051307 8 0.027
regulation of hemocyte proliferation GO:0035206 37 0.027
regulation of cell cycle GO:0051726 291 0.027
chromosome organization GO:0051276 360 0.026
negative regulation of cell cycle phase transition GO:1901988 103 0.026
establishment of spindle localization GO:0051293 22 0.026
establishment of protein localization to plasma membrane GO:0090002 9 0.025
regulation of cellular component biogenesis GO:0044087 201 0.024
mitotic spindle midzone assembly GO:0051256 1 0.024
synaptic vesicle localization GO:0097479 53 0.024
ribonucleoside triphosphate metabolic process GO:0009199 119 0.024
rna localization GO:0006403 115 0.023
meiotic g2 mi transition GO:0008315 3 0.023
chromosome condensation GO:0030261 41 0.023
microtubule based transport GO:0010970 42 0.023
spindle localization GO:0051653 22 0.023
positive regulation of response to stimulus GO:0048584 323 0.022
germarium derived oocyte differentiation GO:0030706 29 0.022
negative regulation of protein processing GO:0010955 31 0.022
protein catabolic process GO:0030163 101 0.021
gland morphogenesis GO:0022612 145 0.021
regulation of cellular protein catabolic process GO:1903362 44 0.021
fusome organization GO:0045478 13 0.021
nicotinamide nucleotide metabolic process GO:0046496 2 0.021
catabolic process GO:0009056 409 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
negative regulation of sister chromatid segregation GO:0033046 13 0.020
regulation of catalytic activity GO:0050790 185 0.019
chromosome movement towards spindle pole GO:0051305 4 0.019
regulation of sister chromatid segregation GO:0033045 28 0.019
negative regulation of protein catabolic process GO:0042177 17 0.019
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.019
sensory perception of mechanical stimulus GO:0050954 72 0.018
membrane organization GO:0061024 112 0.018
nucleoside monophosphate metabolic process GO:0009123 52 0.018
establishment of mitotic spindle localization GO:0040001 17 0.018
mitotic chromosome condensation GO:0007076 22 0.018
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
meiotic chromosome condensation GO:0010032 3 0.018
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.017
cellular protein modification process GO:0006464 438 0.017
cellular macromolecule localization GO:0070727 220 0.017
female meiosis i GO:0007144 8 0.017
single organism intracellular transport GO:1902582 207 0.017
protein modification process GO:0036211 438 0.016
reproductive structure development GO:0048608 74 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.016
phosphorylation GO:0016310 294 0.016
atp metabolic process GO:0046034 49 0.016
regulation of molecular function GO:0065009 217 0.016
cilium assembly GO:0042384 38 0.016
modification dependent protein catabolic process GO:0019941 78 0.016
pronuclear fusion GO:0007344 4 0.015
negative regulation of chromosome organization GO:2001251 19 0.015
poly a mrna export from nucleus GO:0016973 5 0.015
regulation of meiosis GO:0040020 3 0.015
photoreceptor cell fate commitment GO:0046552 41 0.015
reproductive system development GO:0061458 74 0.015
regulation of exit from mitosis GO:0007096 7 0.014
regulation of intracellular transport GO:0032386 64 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
positive regulation of signaling GO:0023056 243 0.014
secretion by cell GO:0032940 101 0.014
nuclear import GO:0051170 51 0.014
negative regulation of cell cycle process GO:0010948 109 0.014
dna packaging GO:0006323 91 0.014
regulation of ras protein signal transduction GO:0046578 93 0.013
cytoplasmic transport GO:0016482 130 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
cell maturation GO:0048469 144 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
regulation of proteasomal protein catabolic process GO:0061136 39 0.013
negative regulation of organelle organization GO:0010639 56 0.013
chromosome organization involved in meiosis GO:0070192 10 0.013
negative regulation of cellular catabolic process GO:0031330 34 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
digestive tract development GO:0048565 149 0.013
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.013
ribose phosphate metabolic process GO:0019693 145 0.012
regulation of protein dephosphorylation GO:0035304 5 0.012
regulation of catabolic process GO:0009894 170 0.012
single organism catabolic process GO:0044712 228 0.012
meiotic cell cycle phase transition GO:0044771 4 0.012
protein phosphorylation GO:0006468 169 0.012
establishment of vesicle localization GO:0051650 51 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.012
oocyte construction GO:0007308 112 0.011
sensory organ morphogenesis GO:0090596 260 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.011
cell cycle g1 s phase transition GO:0044843 31 0.011
cellular catabolic process GO:0044248 372 0.011
nuclear transport GO:0051169 72 0.011
positive regulation of transferase activity GO:0051347 26 0.011
spermatocyte division GO:0048137 13 0.011
establishment of meiotic spindle localization GO:0051295 3 0.011
salivary gland development GO:0007431 162 0.011
meiosis i cytokinesis GO:0007110 12 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.010
protein dephosphorylation GO:0006470 27 0.010
cytokinetic cell separation GO:0000920 1 0.010
establishment of synaptic vesicle localization GO:0097480 50 0.010
golgi organization GO:0007030 66 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
regulation of nucleocytoplasmic transport GO:0046822 35 0.010
establishment of epithelial cell polarity GO:0090162 13 0.010
intracellular mrna localization GO:0008298 66 0.010
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.010
centrosome localization GO:0051642 14 0.010

asl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.073
congenital nervous system abnormality DOID:2490 0 0.073
disease of anatomical entity DOID:7 0 0.022
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011