Drosophila melanogaster

5 known processes

Lip1 (Dmel_CG7279)

Lipase 1

(Aliases: Dmlip1,lip1,LIP1Dm,Lip,dLip1,CG7279,Dmel\CG7279)

Lip1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell cell signaling involved in cell fate commitment GO:0045168 210 0.048
wing disc morphogenesis GO:0007472 344 0.044
imaginal disc derived appendage development GO:0048737 399 0.043
appendage development GO:0048736 401 0.036
lateral inhibition GO:0046331 206 0.034
imaginal disc derived appendage morphogenesis GO:0035114 395 0.033
post embryonic appendage morphogenesis GO:0035120 385 0.033
negative regulation of cellular metabolic process GO:0031324 382 0.033
salivary gland development GO:0007431 162 0.031
actin cytoskeleton organization GO:0030036 206 0.031
imaginal disc derived wing morphogenesis GO:0007476 337 0.031
regulation of localization GO:0032879 275 0.030
body morphogenesis GO:0010171 2 0.030
sterol homeostasis GO:0055092 4 0.028
Fly
programmed cell death GO:0012501 257 0.028
cellular protein modification process GO:0006464 438 0.027
establishment of localization in cell GO:0051649 402 0.027
cell death GO:0008219 279 0.027
catabolic process GO:0009056 409 0.027
appendage morphogenesis GO:0035107 397 0.027
salivary gland morphogenesis GO:0007435 145 0.026
positive regulation of response to stimulus GO:0048584 323 0.026
response to other organism GO:0051707 293 0.026
phagocytosis GO:0006909 215 0.026
chemotaxis GO:0006935 249 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.025
organelle fission GO:0048285 340 0.025
response to lipopolysaccharide GO:0032496 4 0.025
endocytosis GO:0006897 310 0.024
gland development GO:0048732 191 0.024
cholesterol homeostasis GO:0042632 3 0.024
Fly
cellular catabolic process GO:0044248 372 0.023
organic substance catabolic process GO:1901575 308 0.023
vesicle mediated transport GO:0016192 381 0.023
response to biotic stimulus GO:0009607 294 0.023
forebrain development GO:0030900 2 0.023
response to external biotic stimulus GO:0043207 293 0.023
neurological system process GO:0050877 358 0.022
neuron projection guidance GO:0097485 241 0.022
nuclear division GO:0000280 332 0.022
regulation of phosphate metabolic process GO:0019220 210 0.022
organonitrogen compound metabolic process GO:1901564 318 0.022
chaeta development GO:0022416 97 0.022
defense response GO:0006952 300 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
actin filament based process GO:0030029 220 0.021
regionalization GO:0003002 416 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.021
taxis GO:0042330 304 0.021
regulation of sequestering of triglyceride GO:0010889 3 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.021
small molecule metabolic process GO:0044281 305 0.021
Yeast Rat
histolysis GO:0007559 102 0.021
axon guidance GO:0007411 233 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
developmental programmed cell death GO:0010623 138 0.020
detection of stimulus GO:0051606 156 0.020
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
response to abiotic stimulus GO:0009628 341 0.020
cellular amine metabolic process GO:0044106 12 0.020
death GO:0016265 284 0.020
homeostatic process GO:0042592 199 0.020
Fly
immune system process GO:0002376 347 0.020
chromosome organization GO:0051276 360 0.019
negative regulation of gene expression GO:0010629 387 0.019
exocrine system development GO:0035272 162 0.019
cell proliferation GO:0008283 299 0.019
single organism behavior GO:0044708 391 0.019
positive regulation of cell communication GO:0010647 250 0.019
actin filament organization GO:0007015 126 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.019
response to organic substance GO:0010033 284 0.019
intracellular transport GO:0046907 228 0.019
protein modification process GO:0036211 438 0.019
amine metabolic process GO:0009308 12 0.019
organic substance transport GO:0071702 257 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
positive regulation of signal transduction GO:0009967 223 0.018
positive regulation of sequestering of triglyceride GO:0010890 1 0.018
proteolysis GO:0006508 192 0.018
cellular response to organic substance GO:0071310 132 0.018
intracellular signal transduction GO:0035556 300 0.018
positive regulation of gene expression GO:0010628 290 0.018
epithelial cell development GO:0002064 274 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
axon development GO:0061564 297 0.018
negative regulation of nucleic acid templated transcription GO:1903507 240 0.018
response to oxygen containing compound GO:1901700 200 0.018
camera type eye development GO:0043010 4 0.018
tissue death GO:0016271 102 0.018
spindle organization GO:0007051 253 0.018
compound eye development GO:0048749 307 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
axonogenesis GO:0007409 290 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
cell motility GO:0048870 251 0.017
single organism intracellular transport GO:1902582 207 0.017
positive regulation of signaling GO:0023056 243 0.017
protein localization GO:0008104 284 0.017
oxoacid metabolic process GO:0043436 103 0.017
Rat
developmental growth GO:0048589 280 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
phosphorylation GO:0016310 294 0.017
immune response activating signal transduction GO:0002757 2 0.017
kidney development GO:0001822 3 0.017
regulation of molecular function GO:0065009 217 0.017
eye development GO:0001654 323 0.017
developmental maturation GO:0021700 172 0.017
regulation of transport GO:0051049 181 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
negative regulation of transcription dna templated GO:0045892 237 0.016
regulation of cell cycle GO:0051726 291 0.016
cell recognition GO:0008037 102 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
defense response to bacterium GO:0042742 178 0.016
positive regulation of cell migration GO:0030335 2 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
epithelial cell differentiation GO:0030855 322 0.016
ethanolamine containing compound metabolic process GO:0042439 4 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
immune response regulating signaling pathway GO:0002764 2 0.016
macromolecule catabolic process GO:0009057 161 0.016
autophagic cell death GO:0048102 83 0.016
negative regulation of rna biosynthetic process GO:1902679 240 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
connective tissue development GO:0061448 3 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
axis specification GO:0009798 167 0.016
mitotic spindle organization GO:0007052 220 0.016
multicellular organismal aging GO:0010259 140 0.015
negative regulation of biosynthetic process GO:0009890 277 0.015
salivary gland histolysis GO:0035070 88 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
neuron recognition GO:0008038 101 0.015
immune response GO:0006955 246 0.015
endomembrane system organization GO:0010256 119 0.015
response to organophosphorus GO:0046683 2 0.015
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
defense response to other organism GO:0098542 225 0.015
triglyceride biosynthetic process GO:0019432 2 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
mitotic nuclear division GO:0007067 213 0.015
cell division GO:0051301 248 0.015
regulation of protein metabolic process GO:0051246 256 0.015
tissue morphogenesis GO:0048729 297 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
cytoplasmic transport GO:0016482 130 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
segmentation GO:0035282 207 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
chromosome segregation GO:0007059 157 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
response to copper ion GO:0046688 4 0.014
regulation of organelle organization GO:0033043 196 0.014
cellular ketone metabolic process GO:0042180 24 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
mrna metabolic process GO:0016071 124 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
mapk cascade GO:0000165 107 0.014
regulation of catalytic activity GO:0050790 185 0.014
positive regulation of cell motility GO:2000147 3 0.014
single organism cellular localization GO:1902580 180 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
acylglycerol catabolic process GO:0046464 3 0.014
immune effector process GO:0002252 98 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
blastoderm segmentation GO:0007350 159 0.014
salivary gland cell autophagic cell death GO:0035071 83 0.013
maintenance of location GO:0051235 73 0.013
triglyceride catabolic process GO:0019433 3 0.013
anion homeostasis GO:0055081 3 0.013
single organism catabolic process GO:0044712 228 0.013
central nervous system development GO:0007417 201 0.013
negative regulation of signal transduction GO:0009968 206 0.013
organophosphate metabolic process GO:0019637 195 0.013
regulation of immune system process GO:0002682 176 0.013
localization of cell GO:0051674 257 0.013
anterior posterior pattern specification GO:0009952 136 0.013
growth GO:0040007 359 0.013
sensory perception GO:0007600 196 0.013
response to bacterium GO:0009617 198 0.013
glycerolipid catabolic process GO:0046503 3 0.013
regulation of response to external stimulus GO:0032101 115 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
regulation of response to stress GO:0080134 200 0.013
negative regulation of developmental process GO:0051093 201 0.013
embryonic axis specification GO:0000578 107 0.013
regulation of multi organism process GO:0043900 131 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
Rat
regulation of phosphorylation GO:0042325 147 0.013
regulation of cellular component size GO:0032535 98 0.013
rna processing GO:0006396 147 0.013
regulation of mapk cascade GO:0043408 92 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
mesenchymal cell development GO:0014031 1 0.013
cuticle development GO:0042335 86 0.013
tripartite regional subdivision GO:0007351 103 0.013
organic acid metabolic process GO:0006082 103 0.013
Rat
regulation of cellular localization GO:0060341 136 0.013
retina development in camera type eye GO:0060041 4 0.013
anterior posterior axis specification GO:0009948 109 0.013
regulation of cell cycle process GO:0010564 181 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
macromolecular complex assembly GO:0065003 256 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
phospholipid homeostasis GO:0055091 1 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
protein complex biogenesis GO:0070271 201 0.012
dna metabolic process GO:0006259 227 0.012
dendrite development GO:0016358 204 0.012
hindbrain development GO:0030902 2 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
regulation of anatomical structure size GO:0090066 163 0.012
phosphatidylethanolamine metabolic process GO:0046337 1 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
eye morphogenesis GO:0048592 260 0.012
telencephalon development GO:0021537 2 0.012
response to radiation GO:0009314 155 0.012
ameboidal type cell migration GO:0001667 151 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
cholesterol transport GO:0030301 2 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
chromatin organization GO:0006325 207 0.012
gland morphogenesis GO:0022612 145 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
chemical homeostasis GO:0048878 92 0.012
Fly
sensory organ morphogenesis GO:0090596 260 0.012
protein complex assembly GO:0006461 200 0.012
regulation of lipid transport GO:0032368 3 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
spinal cord development GO:0021510 1 0.012
limb development GO:0060173 1 0.012
protein phosphorylation GO:0006468 169 0.012
meiotic cell cycle GO:0051321 171 0.012
dendrite morphogenesis GO:0048813 199 0.012
regulation of developmental growth GO:0048638 174 0.012
regulation of hydrolase activity GO:0051336 97 0.012
positive regulation of lipid storage GO:0010884 4 0.012
humoral immune response GO:0006959 117 0.012
response to monosaccharide GO:0034284 4 0.012
establishment or maintenance of cell polarity GO:0007163 167 0.012
heterocycle catabolic process GO:0046700 166 0.012
ras protein signal transduction GO:0007265 88 0.012
meiotic nuclear division GO:0007126 151 0.012
cellular macromolecule localization GO:0070727 220 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
embryonic pattern specification GO:0009880 174 0.012
apoptotic process GO:0006915 159 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
innate immune response GO:0045087 144 0.011
lipid metabolic process GO:0006629 121 0.011
Yeast Rat
ion transport GO:0006811 145 0.011
regulation of immune response GO:0050776 118 0.011
negative regulation of cell communication GO:0010648 223 0.011
compound eye morphogenesis GO:0001745 249 0.011
organelle assembly GO:0070925 198 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
regulation of cell differentiation GO:0045595 302 0.011
limb morphogenesis GO:0035108 1 0.011
neutral lipid biosynthetic process GO:0046460 2 0.011
neutral lipid catabolic process GO:0046461 3 0.011
cellular homeostasis GO:0019725 80 0.011
ovarian follicle cell development GO:0030707 248 0.011
innate immune response activating signal transduction GO:0002758 2 0.011
antimicrobial humoral response GO:0019730 99 0.011
golgi organization GO:0007030 66 0.011
nephron development GO:0072006 3 0.011
establishment of protein localization GO:0045184 163 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
acylglycerol biosynthetic process GO:0046463 2 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
negative regulation of signaling GO:0023057 219 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
photoreceptor cell development GO:0042461 96 0.011
detection of chemical stimulus GO:0009593 93 0.011
tube development GO:0035295 244 0.011
autophagy GO:0006914 108 0.011
response to hexose GO:0009746 3 0.010
protein heterooligomerization GO:0051291 4 0.010
single organism biosynthetic process GO:0044711 206 0.010
anatomical structure homeostasis GO:0060249 97 0.010
camera type eye morphogenesis GO:0048593 2 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
cell cycle phase transition GO:0044770 140 0.010
positive regulation of molecular function GO:0044093 136 0.010
dephosphorylation GO:0016311 51 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
response to organic cyclic compound GO:0014070 89 0.010
adult locomotory behavior GO:0008344 76 0.010
imaginal disc derived leg morphogenesis GO:0007480 80 0.010
protein processing GO:0016485 68 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
secretion GO:0046903 109 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010
regulation of growth GO:0040008 233 0.010
embryonic development via the syncytial blastoderm GO:0001700 148 0.010
phosphatidic acid metabolic process GO:0046473 1 0.010
digestive tract development GO:0048565 149 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
regulation of cell death GO:0010941 173 0.010
pattern recognition receptor signaling pathway GO:0002221 2 0.010
regulation of cell morphogenesis GO:0022604 163 0.010
estrogen metabolic process GO:0008210 1 0.010
regulation of mitotic cell cycle phase transition GO:1901990 130 0.010
pigmentation GO:0043473 75 0.010
cellular lipid metabolic process GO:0044255 83 0.010
Yeast Rat

Lip1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.023
disease of metabolism DOID:0014667 0 0.016
carbohydrate metabolism disease DOID:0050013 0 0.016
glucose metabolism disease DOID:4194 0 0.016
acquired metabolic disease DOID:0060158 0 0.016
inherited metabolic disorder DOID:655 0 0.016
sensory system disease DOID:0050155 0 0.016
diabetes mellitus DOID:9351 0 0.015
type 2 diabetes mellitus DOID:9352 0 0.015
musculoskeletal system disease DOID:17 0 0.015
familial hyperlipidemia DOID:1168 0 0.011
lipid metabolism disorder DOID:3146 0 0.011
familial combined hyperlipidemia DOID:13809 0 0.011
cardiovascular system disease DOID:1287 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
hair disease DOID:421 0 0.011
integumentary system disease DOID:16 0 0.011