Drosophila melanogaster

86 known processes

Plip (Dmel_CG10371)

PTEN-like phosphatase

(Aliases: PLIP,Dmel\CG10371,CG10371,150466_at)

Plip biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound metabolic process GO:1901564 318 0.044
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.028
regulation of cell cycle phase transition GO:1901987 130 0.028
transcription from rna polymerase ii promoter GO:0006366 368 0.026
protein transport GO:0015031 155 0.025
response to organic substance GO:0010033 284 0.025
establishment of localization in cell GO:0051649 402 0.025
segmentation GO:0035282 207 0.025
defense response to bacterium GO:0042742 178 0.024
blastoderm segmentation GO:0007350 159 0.024
cellular catabolic process GO:0044248 372 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
positive regulation of signaling GO:0023056 243 0.023
organic substance catabolic process GO:1901575 308 0.022
defense response to other organism GO:0098542 225 0.022
response to lipopolysaccharide GO:0032496 4 0.022
positive regulation of rna metabolic process GO:0051254 271 0.022
cytoplasmic transport GO:0016482 130 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.021
response to other organism GO:0051707 293 0.021
negative regulation of signal transduction GO:0009968 206 0.021
defense response GO:0006952 300 0.021
anterior posterior axis specification embryo GO:0008595 103 0.021
small molecule metabolic process GO:0044281 305 0.021
catabolic process GO:0009056 409 0.020
nucleotide metabolic process GO:0009117 161 0.020
immune response GO:0006955 246 0.020
protein modification process GO:0036211 438 0.020
phagocytosis GO:0006909 215 0.020
mrna splicing via spliceosome GO:0000398 73 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
organic substance transport GO:0071702 257 0.020
response to bacterium GO:0009617 198 0.020
benzene containing compound metabolic process GO:0042537 3 0.019
cellular protein modification process GO:0006464 438 0.019
response to external biotic stimulus GO:0043207 293 0.019
mrna processing GO:0006397 104 0.019
positive regulation of cell communication GO:0010647 250 0.019
protein localization GO:0008104 284 0.018
embryonic pattern specification GO:0009880 174 0.018
cellular macromolecule catabolic process GO:0044265 136 0.018
secretion GO:0046903 109 0.018
regulation of molecular function GO:0065009 217 0.018
intracellular signal transduction GO:0035556 300 0.018
positive regulation of signal transduction GO:0009967 223 0.018
cellular macromolecule localization GO:0070727 220 0.018
ras protein signal transduction GO:0007265 88 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
single organism catabolic process GO:0044712 228 0.018
mrna metabolic process GO:0016071 124 0.017
taxis GO:0042330 304 0.017
endocytosis GO:0006897 310 0.017
positive regulation of transcription dna templated GO:0045893 266 0.017
positive regulation of gene expression GO:0010628 290 0.017
vesicle mediated transport GO:0016192 381 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
ion transport GO:0006811 145 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
cell death GO:0008219 279 0.016
response to oxygen containing compound GO:1901700 200 0.016
response to biotic stimulus GO:0009607 294 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
anterior posterior axis specification GO:0009948 109 0.016
anterior posterior pattern specification GO:0009952 136 0.016
immune system process GO:0002376 347 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
embryonic axis specification GO:0000578 107 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
macromolecule catabolic process GO:0009057 161 0.015
phosphorylation GO:0016310 294 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
appendage development GO:0048736 401 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
ribonucleotide catabolic process GO:0009261 109 0.015
regulation of immune response GO:0050776 118 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
regulation of immune system process GO:0002682 176 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
heterocycle catabolic process GO:0046700 166 0.015
forebrain development GO:0030900 2 0.015
intracellular transport GO:0046907 228 0.014
aromatic compound catabolic process GO:0019439 166 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
positive regulation of molecular function GO:0044093 136 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
single organism biosynthetic process GO:0044711 206 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
establishment of protein localization GO:0045184 163 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
regulation of cell cycle GO:0051726 291 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
cellular response to organic substance GO:0071310 132 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.013
regulation of protein metabolic process GO:0051246 256 0.013
cell cycle phase transition GO:0044770 140 0.013
regulation of catalytic activity GO:0050790 185 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
oocyte differentiation GO:0009994 145 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
innate immune response GO:0045087 144 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
cellular response to endogenous stimulus GO:0071495 80 0.013
purine containing compound metabolic process GO:0072521 155 0.013
single organism intracellular transport GO:1902582 207 0.013
nucleotide catabolic process GO:0009166 109 0.013
body morphogenesis GO:0010171 2 0.013
rna processing GO:0006396 147 0.013
negative regulation of developmental process GO:0051093 201 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
nucleoside catabolic process GO:0009164 112 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
cellular homeostasis GO:0019725 80 0.012
mushroom body development GO:0016319 70 0.012
regulation of rna splicing GO:0043484 69 0.012
response to nutrient levels GO:0031667 114 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
wound healing GO:0042060 75 0.012
intracellular protein transport GO:0006886 104 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
proteolysis GO:0006508 192 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
regulation of response to stress GO:0080134 200 0.012
organic acid metabolic process GO:0006082 103 0.012
head development GO:0060322 135 0.012
mitotic nuclear division GO:0007067 213 0.012
positive regulation of cellular biosynthetic process GO:0031328 316 0.012
lateral inhibition GO:0046331 206 0.012
organophosphate metabolic process GO:0019637 195 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
immune response activating signal transduction GO:0002757 2 0.012
negative regulation of cell communication GO:0010648 223 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
transmembrane transport GO:0055085 139 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
glycosyl compound catabolic process GO:1901658 112 0.011
nuclear division GO:0000280 332 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
camera type eye development GO:0043010 4 0.011
central nervous system development GO:0007417 201 0.011
wing disc morphogenesis GO:0007472 344 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
regulation of cell development GO:0060284 215 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
regulation of defense response GO:0031347 102 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
nucleoside metabolic process GO:0009116 127 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
spermatogenesis GO:0007283 200 0.011
tripartite regional subdivision GO:0007351 103 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
regulation of hydrolase activity GO:0051336 97 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
positive regulation of cell motility GO:2000147 3 0.011
response to organophosphorus GO:0046683 2 0.010
activation of innate immune response GO:0002218 4 0.010
regulation of catabolic process GO:0009894 170 0.010
nuclear transport GO:0051169 72 0.010
response to starvation GO:0042594 97 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.010
positive regulation of cell migration GO:0030335 2 0.010
regulation of mrna splicing via spliceosome GO:0048024 64 0.010
regionalization GO:0003002 416 0.010
positive regulation of hydrolase activity GO:0051345 78 0.010
negative regulation of gene expression GO:0010629 387 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
kidney development GO:0001822 3 0.010
mapk cascade GO:0000165 107 0.010
regulation of mrna processing GO:0050684 71 0.010

Plip disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010