Drosophila melanogaster

26 known processes

aph-1 (Dmel_CG2855)

anterior pharynx defective 1

(Aliases: pen-1,l(2)23AB6,aph1,dAph-1,l(2)23Ag,Pen-1,aph,Dm APH-1,Dmel\CG2855,CG2855,Aph-1)

aph-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic dna damage checkpoint GO:0044773 74 0.110
catabolic process GO:0009056 409 0.095
negative regulation of cell cycle GO:0045786 116 0.073
protein modification process GO:0036211 438 0.060
embryo development ending in birth or egg hatching GO:0009792 152 0.058
cellular catabolic process GO:0044248 372 0.054
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.053
establishment of localization in cell GO:0051649 402 0.052
embryonic morphogenesis GO:0048598 206 0.052
golgi vesicle transport GO:0048193 27 0.045
cellular macromolecule localization GO:0070727 220 0.044
endomembrane system organization GO:0010256 119 0.043
meiotic cell cycle GO:0051321 171 0.043
imaginal disc derived appendage morphogenesis GO:0035114 395 0.041
organonitrogen compound metabolic process GO:1901564 318 0.038
transcription from rna polymerase ii promoter GO:0006366 368 0.038
appendage development GO:0048736 401 0.036
appendage morphogenesis GO:0035107 397 0.035
cellular protein localization GO:0034613 160 0.034
spindle organization GO:0007051 253 0.033
nuclear division GO:0000280 332 0.033
cellular protein modification process GO:0006464 438 0.031
intracellular transport GO:0046907 228 0.030
regulation of mitotic cell cycle GO:0007346 190 0.030
vesicle mediated transport GO:0016192 381 0.030
protein localization GO:0008104 284 0.030
single organism catabolic process GO:0044712 228 0.030
negative regulation of cell cycle phase transition GO:1901988 103 0.029
regulation of cell cycle GO:0051726 291 0.028
negative regulation of cell cycle process GO:0010948 109 0.028
regulation of multicellular organismal development GO:2000026 414 0.027
imaginal disc derived wing morphogenesis GO:0007476 337 0.027
organic substance catabolic process GO:1901575 308 0.027
synaptic transmission GO:0007268 288 0.026
cell cycle phase transition GO:0044770 140 0.026
post embryonic appendage morphogenesis GO:0035120 385 0.026
wing disc morphogenesis GO:0007472 344 0.024
tissue morphogenesis GO:0048729 297 0.023
regulation of gtp catabolic process GO:0033124 44 0.023
learning GO:0007612 75 0.023
intracellular signal transduction GO:0035556 300 0.023
programmed cell death GO:0012501 257 0.023
single organism intracellular transport GO:1902582 207 0.022
learning or memory GO:0007611 141 0.022
cell motility GO:0048870 251 0.022
regulation of cell cycle phase transition GO:1901987 130 0.020
proteolysis GO:0006508 192 0.020
neurological system process GO:0050877 358 0.020
epithelial cell development GO:0002064 274 0.020
regulation of mitotic cell cycle phase transition GO:1901990 130 0.019
cell proliferation GO:0008283 299 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
regionalization GO:0003002 416 0.018
chromosome organization GO:0051276 360 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
cell cycle checkpoint GO:0000075 95 0.017
morphogenesis of an epithelium GO:0002009 276 0.017
cognition GO:0050890 141 0.017
macromolecule catabolic process GO:0009057 161 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
positive regulation of signaling GO:0023056 243 0.017
apoptotic process GO:0006915 159 0.017
mitotic cell cycle checkpoint GO:0007093 88 0.017
protein catabolic process GO:0030163 101 0.016
meiotic cell cycle process GO:1903046 132 0.016
response to organic substance GO:0010033 284 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
death GO:0016265 284 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
positive regulation of signal transduction GO:0009967 223 0.015
eye development GO:0001654 323 0.015
sensory organ morphogenesis GO:0090596 260 0.015
cytoplasmic transport GO:0016482 130 0.015
positive regulation of apoptotic signaling pathway GO:2001235 4 0.015
regulation of developmental growth GO:0048638 174 0.015
ras protein signal transduction GO:0007265 88 0.015
peptidyl amino acid modification GO:0018193 105 0.015
cell death GO:0008219 279 0.015
regulation of cell proliferation GO:0042127 163 0.015
positive regulation of gene expression GO:0010628 290 0.015
purine ribonucleotide catabolic process GO:0009154 109 0.015
respiratory system development GO:0060541 213 0.014
imaginal disc derived appendage development GO:0048737 399 0.014
organelle assembly GO:0070925 198 0.014
aromatic compound catabolic process GO:0019439 166 0.014
response to temperature stimulus GO:0009266 106 0.014
multi multicellular organism process GO:0044706 123 0.014
notch receptor processing GO:0007220 13 0.014
negative regulation of signaling GO:0023057 219 0.014
signal release GO:0023061 49 0.013
localization of cell GO:0051674 257 0.013
negative regulation of gene expression GO:0010629 387 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.013
phagocytosis GO:0006909 215 0.013
regulation of response to stress GO:0080134 200 0.013
larval development GO:0002164 104 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
compound eye development GO:0048749 307 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
response to other organism GO:0051707 293 0.012
single organism membrane organization GO:0044802 93 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
establishment of protein localization GO:0045184 163 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
wnt signaling pathway GO:0016055 98 0.012
dna templated transcription initiation GO:0006352 25 0.012
regulation of protein catabolic process GO:0042176 55 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
neuromuscular synaptic transmission GO:0007274 67 0.011
dna integrity checkpoint GO:0031570 81 0.011
macromolecular complex assembly GO:0065003 256 0.011
membrane organization GO:0061024 112 0.011
camera type eye development GO:0043010 4 0.011
small molecule metabolic process GO:0044281 305 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
developmental growth GO:0048589 280 0.011
response to external biotic stimulus GO:0043207 293 0.011
synaptic growth at neuromuscular junction GO:0051124 119 0.010
response to oxygen containing compound GO:1901700 200 0.010
regulation of programmed cell death GO:0043067 152 0.010
response to starvation GO:0042594 97 0.010
telencephalon development GO:0021537 2 0.010

aph-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
nervous system disease DOID:863 0 0.012