Drosophila melanogaster

34 known processes

Fbw5 (Dmel_CG9144)

CG9144 gene product from transcript CG9144-RA

(Aliases: dFbw5,Dmel\CG9144,CG9144)

Fbw5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lateral inhibition GO:0046331 206 0.085
establishment of localization in cell GO:0051649 402 0.073
cell cell signaling involved in cell fate commitment GO:0045168 210 0.069
cellular protein modification process GO:0006464 438 0.066
intracellular transport GO:0046907 228 0.062
positive regulation of macromolecule metabolic process GO:0010604 405 0.059
cell proliferation GO:0008283 299 0.057
single organism membrane organization GO:0044802 93 0.053
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.048
regulation of protein metabolic process GO:0051246 256 0.046
cellular catabolic process GO:0044248 372 0.046
Human
regulation of localization GO:0032879 275 0.045
catabolic process GO:0009056 409 0.045
organic substance catabolic process GO:1901575 308 0.044
positive regulation of rna metabolic process GO:0051254 271 0.043
growth GO:0040007 359 0.043
ras protein signal transduction GO:0007265 88 0.041
organonitrogen compound metabolic process GO:1901564 318 0.040
regulation of cellular protein metabolic process GO:0032268 243 0.040
intracellular signal transduction GO:0035556 300 0.039
protein modification process GO:0036211 438 0.039
transcription from rna polymerase ii promoter GO:0006366 368 0.038
positive regulation of signal transduction GO:0009967 223 0.037
cellular macromolecule localization GO:0070727 220 0.036
positive regulation of nucleic acid templated transcription GO:1903508 266 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.034
single organism cellular localization GO:1902580 180 0.034
regulation of molecular function GO:0065009 217 0.033
phosphorylation GO:0016310 294 0.033
single organism intracellular transport GO:1902582 207 0.033
cell division GO:0051301 248 0.032
single organism behavior GO:0044708 391 0.032
regulation of cell cycle GO:0051726 291 0.032
positive regulation of gene expression GO:0010628 290 0.032
developmental growth GO:0048589 280 0.031
small molecule metabolic process GO:0044281 305 0.031
protein localization GO:0008104 284 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.030
regulation of intracellular signal transduction GO:1902531 236 0.030
protein transport GO:0015031 155 0.030
positive regulation of response to stimulus GO:0048584 323 0.029
establishment of protein localization GO:0045184 163 0.029
cellular protein localization GO:0034613 160 0.029
regulation of transport GO:0051049 181 0.028
positive regulation of cellular catabolic process GO:0031331 95 0.028
regulation of phosphorus metabolic process GO:0051174 210 0.028
cytoplasmic transport GO:0016482 130 0.028
appendage morphogenesis GO:0035107 397 0.028
cellular response to dna damage stimulus GO:0006974 223 0.027
vesicle mediated transport GO:0016192 381 0.027
cellular macromolecule catabolic process GO:0044265 136 0.027
Human
regulation of catabolic process GO:0009894 170 0.027
neurological system process GO:0050877 358 0.027
endomembrane system organization GO:0010256 119 0.027
membrane organization GO:0061024 112 0.027
organic substance transport GO:0071702 257 0.026
post embryonic appendage morphogenesis GO:0035120 385 0.026
positive regulation of biosynthetic process GO:0009891 316 0.025
nucleus organization GO:0006997 45 0.025
regulation of catalytic activity GO:0050790 185 0.025
positive regulation of signaling GO:0023056 243 0.025
small gtpase mediated signal transduction GO:0007264 88 0.025
body morphogenesis GO:0010171 2 0.025
rna processing GO:0006396 147 0.025
regulation of cellular localization GO:0060341 136 0.025
appendage development GO:0048736 401 0.024
regulation of organelle organization GO:0033043 196 0.024
organelle fission GO:0048285 340 0.024
positive regulation of cell communication GO:0010647 250 0.023
phagocytosis GO:0006909 215 0.023
macromolecule catabolic process GO:0009057 161 0.022
spermatogenesis GO:0007283 200 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.021
endocytosis GO:0006897 310 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
cell death GO:0008219 279 0.021
chromatin organization GO:0006325 207 0.021
tube development GO:0035295 244 0.021
nuclear division GO:0000280 332 0.021
death GO:0016265 284 0.021
single organism biosynthetic process GO:0044711 206 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
localization of cell GO:0051674 257 0.021
positive regulation of rna biosynthetic process GO:1902680 266 0.020
positive regulation of catabolic process GO:0009896 105 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
positive regulation of cellular component organization GO:0051130 156 0.020
positive regulation of molecular function GO:0044093 136 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.020
intracellular protein transport GO:0006886 104 0.020
regulation of cellular catabolic process GO:0031329 157 0.020
open tracheal system development GO:0007424 204 0.019
positive regulation of transport GO:0051050 92 0.019
organophosphate metabolic process GO:0019637 195 0.019
regulation of cell development GO:0060284 215 0.019
regulation of multicellular organismal development GO:2000026 414 0.019
negative regulation of gene expression GO:0010629 387 0.019
carbohydrate derivative metabolic process GO:1901135 217 0.019
programmed cell death GO:0012501 257 0.019
regulation of growth GO:0040008 233 0.019
wing disc morphogenesis GO:0007472 344 0.018
response to oxygen containing compound GO:1901700 200 0.018
regulation of cell cycle process GO:0010564 181 0.018
cellular protein catabolic process GO:0044257 83 0.018
Human
homeostatic process GO:0042592 199 0.018
negative regulation of cell communication GO:0010648 223 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
negative regulation of signal transduction GO:0009968 206 0.018
regulation of cellular component biogenesis GO:0044087 201 0.018
tissue morphogenesis GO:0048729 297 0.018
proteolysis GO:0006508 192 0.017
Human
positive regulation of protein metabolic process GO:0051247 128 0.017
protein phosphorylation GO:0006468 169 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.017
imaginal disc derived appendage development GO:0048737 399 0.017
tube morphogenesis GO:0035239 191 0.017
imaginal disc derived wing morphogenesis GO:0007476 337 0.017
secretion GO:0046903 109 0.017
axon development GO:0061564 297 0.017
cell migration GO:0016477 238 0.017
taxis GO:0042330 304 0.017
regulation of anatomical structure size GO:0090066 163 0.017
peptidyl threonine phosphorylation GO:0018107 2 0.017
regulation of cell differentiation GO:0045595 302 0.017
chromosome organization GO:0051276 360 0.016
negative regulation of developmental process GO:0051093 201 0.016
protein complex assembly GO:0006461 200 0.016
developmental maturation GO:0021700 172 0.016
protein catabolic process GO:0030163 101 0.016
spindle organization GO:0007051 253 0.016
actin cytoskeleton organization GO:0030036 206 0.016
negative regulation of cellular metabolic process GO:0031324 382 0.016
centrosome organization GO:0051297 163 0.016
Human
regulation of phosphorylation GO:0042325 147 0.016
modification dependent macromolecule catabolic process GO:0043632 79 0.016
Human
peptidyl amino acid modification GO:0018193 105 0.016
oxoacid metabolic process GO:0043436 103 0.016
response to external biotic stimulus GO:0043207 293 0.016
vesicle organization GO:0016050 44 0.016
single organism carbohydrate metabolic process GO:0044723 72 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.015
positive regulation of apoptotic signaling pathway GO:2001235 4 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
response to abiotic stimulus GO:0009628 341 0.015
positive regulation of cellular protein metabolic process GO:0032270 118 0.015
defense response to other organism GO:0098542 225 0.015
g protein coupled receptor signaling pathway GO:0007186 136 0.015
respiratory system development GO:0060541 213 0.015
nucleobase containing compound catabolic process GO:0034655 165 0.015
regulation of ras protein signal transduction GO:0046578 93 0.015
response to organic substance GO:0010033 284 0.015
protein complex biogenesis GO:0070271 201 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
kidney development GO:0001822 3 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
chemotaxis GO:0006935 249 0.014
cell maturation GO:0048469 144 0.014
meiotic cell cycle GO:0051321 171 0.014
macromolecular complex assembly GO:0065003 256 0.014
response to oxidative stress GO:0006979 86 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
regulation of establishment of protein localization GO:0070201 61 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
regulation of cell death GO:0010941 173 0.014
epithelium migration GO:0090132 148 0.014
forebrain development GO:0030900 2 0.014
nucleotide metabolic process GO:0009117 161 0.014
positive regulation of transcription dna templated GO:0045893 266 0.013
camera type eye development GO:0043010 4 0.013
meiotic cell cycle process GO:1903046 132 0.013
response to wounding GO:0009611 94 0.013
connective tissue development GO:0061448 3 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
amine metabolic process GO:0009308 12 0.013
organic acid metabolic process GO:0006082 103 0.013
chromosome segregation GO:0007059 157 0.013
neuromuscular junction development GO:0007528 149 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
cell motility GO:0048870 251 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
olfactory behavior GO:0042048 97 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
secretion by cell GO:0032940 101 0.013
response to organophosphorus GO:0046683 2 0.013
sensory perception GO:0007600 196 0.013
nucleotide catabolic process GO:0009166 109 0.013
apoptotic process GO:0006915 159 0.013
actin filament based process GO:0030029 220 0.013
mitotic nuclear division GO:0007067 213 0.013
dna metabolic process GO:0006259 227 0.012
rna 3 end processing GO:0031123 45 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
chromatin modification GO:0016568 147 0.012
cell adhesion GO:0007155 136 0.012
cellular amine metabolic process GO:0044106 12 0.012
embryonic morphogenesis GO:0048598 206 0.012
regulation of response to external stimulus GO:0032101 115 0.012
defense response GO:0006952 300 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
regulation of cell projection organization GO:0031344 92 0.012
response to other organism GO:0051707 293 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
mrna metabolic process GO:0016071 124 0.012
mitotic dna integrity checkpoint GO:0044774 75 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
centrosome cycle GO:0007098 137 0.012
Human
nucleocytoplasmic transport GO:0006913 72 0.012
protein localization to organelle GO:0033365 82 0.012
synapse assembly GO:0007416 143 0.012
response to biotic stimulus GO:0009607 294 0.012
regionalization GO:0003002 416 0.012
regulation of intracellular transport GO:0032386 64 0.011
axon guidance GO:0007411 233 0.011
meiosis i GO:0007127 59 0.011
purine containing compound catabolic process GO:0072523 112 0.011
dendrite development GO:0016358 204 0.011
extracellular structure organization GO:0043062 46 0.011
epithelial cell differentiation GO:0030855 322 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
histone modification GO:0016570 106 0.011
positive regulation of cell motility GO:2000147 3 0.011
ameboidal type cell migration GO:0001667 151 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
positive regulation of proteolysis GO:0045862 52 0.011
oocyte differentiation GO:0009994 145 0.011
cellular ketone metabolic process GO:0042180 24 0.011
regulation of hydrolase activity GO:0051336 97 0.011
digestive tract development GO:0048565 149 0.011
regulation of cell division GO:0051302 72 0.011
nephron development GO:0072006 3 0.011
wound healing GO:0042060 75 0.011
gland development GO:0048732 191 0.011
male gamete generation GO:0048232 201 0.011
aromatic compound catabolic process GO:0019439 166 0.011
maintenance of location GO:0051235 73 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
nuclear transport GO:0051169 72 0.011
determination of adult lifespan GO:0008340 137 0.011
regulation of multi organism process GO:0043900 131 0.011
heterocycle catabolic process GO:0046700 166 0.011
defense response to bacterium GO:0042742 178 0.011
mitotic g2 m transition checkpoint GO:0044818 70 0.011
neuron projection guidance GO:0097485 241 0.011
synapse organization GO:0050808 196 0.011
golgi organization GO:0007030 66 0.011
eye development GO:0001654 323 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
synaptic growth at neuromuscular junction GO:0051124 119 0.010
protein targeting to nucleus GO:0044744 51 0.010
dorsal ventral axis specification GO:0009950 66 0.010
cellular homeostasis GO:0019725 80 0.010
regulation of neuron differentiation GO:0045664 103 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.010
protein dna complex subunit organization GO:0071824 86 0.010
proteasomal protein catabolic process GO:0010498 59 0.010
Human
regulation of nervous system development GO:0051960 248 0.010
central nervous system development GO:0007417 201 0.010
multicellular organismal aging GO:0010259 140 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010
immune system process GO:0002376 347 0.010
synaptic transmission GO:0007268 288 0.010
telencephalon development GO:0021537 2 0.010
regulation of mitotic cell cycle GO:0007346 190 0.010
regulation of protein catabolic process GO:0042176 55 0.010
meiotic nuclear division GO:0007126 151 0.010
response to bacterium GO:0009617 198 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
protein modification by small protein conjugation or removal GO:0070647 106 0.010
regulation of mapk cascade GO:0043408 92 0.010

Fbw5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.058
nervous system disease DOID:863 0 0.025
cardiovascular system disease DOID:1287 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
central nervous system disease DOID:331 0 0.010