Drosophila melanogaster

94 known processes

RpA-70 (Dmel_CG9633)

Replication Protein A 70

(Aliases: RPA,RPA 70,i164,dRP-A,RPA1,DmRPA,D-SSB,CG9633,Dmel\CG9633,dmrpa1,Ssb-70,Rpa-70,RP-A,D-RPA70,RpA70,DRP-A,RPA70)

RpA-70 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 54 0.977
Human
double strand break repair GO:0006302 26 0.964
Human
cellular response to dna damage stimulus GO:0006974 223 0.883
negative regulation of cellular metabolic process GO:0031324 382 0.250
cellular catabolic process GO:0044248 372 0.213
chemotaxis GO:0006935 249 0.181
positive regulation of developmental process GO:0051094 143 0.178
developmental growth GO:0048589 280 0.177
regulation of mitotic cell cycle GO:0007346 190 0.174
regulation of multicellular organism growth GO:0040014 40 0.153
chromatin organization GO:0006325 207 0.151
positive regulation of cellular biosynthetic process GO:0031328 316 0.137
mitotic cell cycle phase transition GO:0044772 138 0.137
dna metabolic process GO:0006259 227 0.126
response to ionizing radiation GO:0010212 32 0.125
proteolysis GO:0006508 192 0.118
double strand break repair via nonhomologous end joining GO:0006303 5 0.114
regulation of cellular response to stress GO:0080135 89 0.111
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.111
regulation of developmental growth GO:0048638 174 0.102
regulation of response to stress GO:0080134 200 0.097
negative regulation of response to stimulus GO:0048585 258 0.096
regulation of gene expression epigenetic GO:0040029 128 0.095
nuclear transport GO:0051169 72 0.093
response to external biotic stimulus GO:0043207 293 0.093
regulation of molecular function GO:0065009 217 0.092
growth GO:0040007 359 0.090
dna integrity checkpoint GO:0031570 81 0.089
cellular amino acid metabolic process GO:0006520 61 0.085
regulation of cell cycle phase transition GO:1901987 130 0.076
establishment of localization in cell GO:0051649 402 0.074
regulation of endopeptidase activity GO:0052548 36 0.071
central nervous system development GO:0007417 201 0.071
taxis GO:0042330 304 0.070
recombinational repair GO:0000725 13 0.064
Human
embryo development ending in birth or egg hatching GO:0009792 152 0.063
negative regulation of gene expression GO:0010629 387 0.063
double strand break repair via homologous recombination GO:0000724 13 0.059
Human
dna damage checkpoint GO:0000077 78 0.057
positive regulation of developmental growth GO:0048639 62 0.055
regulation of cell differentiation GO:0045595 302 0.053
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.051
macromolecule catabolic process GO:0009057 161 0.050
positive regulation of endopeptidase activity GO:0010950 26 0.050
ribonucleoside monophosphate catabolic process GO:0009158 39 0.049
positive regulation of cellular protein metabolic process GO:0032270 118 0.047
cellular response to chemical stimulus GO:0070887 199 0.047
cell recognition GO:0008037 102 0.046
cell death GO:0008219 279 0.046
positive regulation of multicellular organismal process GO:0051240 143 0.044
telomere organization GO:0032200 21 0.044
Human
cellular macromolecule localization GO:0070727 220 0.043
lateral inhibition GO:0046331 206 0.043
anatomical structure homeostasis GO:0060249 97 0.042
Human
regulation of mitotic cell cycle phase transition GO:1901990 130 0.042
protein targeting to nucleus GO:0044744 51 0.042
regulation of cellular protein metabolic process GO:0032268 243 0.039
brain development GO:0007420 120 0.039
negative regulation of transcription dna templated GO:0045892 237 0.039
positive regulation of macromolecule metabolic process GO:0010604 405 0.039
muscle structure development GO:0061061 224 0.039
homeostatic process GO:0042592 199 0.039
Human
apoptotic process GO:0006915 159 0.038
organic cyclic compound catabolic process GO:1901361 168 0.037
positive regulation of protein metabolic process GO:0051247 128 0.037
cell cycle phase transition GO:0044770 140 0.036
programmed cell death GO:0012501 257 0.036
protein localization GO:0008104 284 0.036
cellular macromolecule catabolic process GO:0044265 136 0.035
embryonic heart tube development GO:0035050 22 0.035
transcription from rna polymerase ii promoter GO:0006366 368 0.035
multicellular organism growth GO:0035264 46 0.035
chromatin remodeling GO:0006338 72 0.035
negative regulation of molecular function GO:0044092 51 0.034
negative regulation of nucleic acid templated transcription GO:1903507 240 0.034
regulation of protein metabolic process GO:0051246 256 0.032
positive regulation of signal transduction GO:0009967 223 0.032
multicellular organismal reproductive behavior GO:0033057 110 0.031
positive regulation of rna metabolic process GO:0051254 271 0.031
vesicle mediated transport GO:0016192 381 0.031
cardiovascular system development GO:0072358 82 0.031
organonitrogen compound metabolic process GO:1901564 318 0.031
regulation of cell death GO:0010941 173 0.030
atp metabolic process GO:0046034 49 0.030
positive regulation of nucleic acid templated transcription GO:1903508 266 0.030
regionalization GO:0003002 416 0.030
negative regulation of biosynthetic process GO:0009890 277 0.030
death GO:0016265 284 0.029
single organism biosynthetic process GO:0044711 206 0.029
organic substance transport GO:0071702 257 0.028
muscle organ development GO:0007517 127 0.028
endocytosis GO:0006897 310 0.027
anterior posterior pattern specification GO:0009952 136 0.027
regulation of peptidase activity GO:0052547 39 0.027
positive regulation of phosphorus metabolic process GO:0010562 139 0.026
phosphorylation GO:0016310 294 0.026
aromatic compound catabolic process GO:0019439 166 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
protein maturation GO:0051604 71 0.025
positive regulation of peptidase activity GO:0010952 29 0.024
mitotic dna damage checkpoint GO:0044773 74 0.024
chromosome organization GO:0051276 360 0.024
Human
single organism intracellular transport GO:1902582 207 0.024
positive regulation of response to stimulus GO:0048584 323 0.024
segmentation GO:0035282 207 0.024
positive regulation of cell death GO:0010942 69 0.023
protein catabolic process GO:0030163 101 0.023
cellular response to oxygen containing compound GO:1901701 79 0.023
nucleotide excision repair GO:0006289 8 0.023
Human
gene silencing GO:0016458 138 0.023
negative regulation of signaling GO:0023057 219 0.023
compound eye development GO:0048749 307 0.023
head development GO:0060322 135 0.023
regulation of cell cycle process GO:0010564 181 0.023
aging GO:0007568 143 0.023
response to abiotic stimulus GO:0009628 341 0.023
response to organic substance GO:0010033 284 0.022
notch signaling pathway GO:0007219 120 0.022
macromolecular complex assembly GO:0065003 256 0.022
determination of adult lifespan GO:0008340 137 0.021
positive regulation of gene expression GO:0010628 290 0.021
response to radiation GO:0009314 155 0.020
nucleoside monophosphate metabolic process GO:0009123 52 0.020
nuclear import GO:0051170 51 0.020
positive regulation of signaling GO:0023056 243 0.020
regulation of localization GO:0032879 275 0.020
blastoderm segmentation GO:0007350 159 0.019
positive regulation of molecular function GO:0044093 136 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
positive regulation of proteolysis GO:0045862 52 0.019
protein import GO:0017038 55 0.019
negative regulation of cell communication GO:0010648 223 0.019
positive regulation of cell communication GO:0010647 250 0.018
intracellular transport GO:0046907 228 0.018
dendrite development GO:0016358 204 0.018
response to other organism GO:0051707 293 0.018
multi organism reproductive behavior GO:0044705 121 0.018
response to biotic stimulus GO:0009607 294 0.018
catabolic process GO:0009056 409 0.018
organ growth GO:0035265 56 0.017
regulation of growth GO:0040008 233 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
ribonucleoside monophosphate metabolic process GO:0009161 51 0.017
organic substance catabolic process GO:1901575 308 0.017
anterior posterior axis specification embryo GO:0008595 103 0.017
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.017
regulation of multicellular organismal development GO:2000026 414 0.016
positive regulation of epidermal growth factor activated receptor activity GO:0045741 1 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
purine nucleoside monophosphate catabolic process GO:0009128 38 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
regulation of proteolysis GO:0030162 87 0.016
compound eye morphogenesis GO:0001745 249 0.016
regulation of nervous system development GO:0051960 248 0.016
atp catabolic process GO:0006200 38 0.016
cellular protein catabolic process GO:0044257 83 0.016
cell cycle g1 s phase transition GO:0044843 31 0.015
regulation of establishment of protein localization GO:0070201 61 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
cellular amine metabolic process GO:0044106 12 0.015
cell division GO:0051301 248 0.015
negative regulation of mitotic cell cycle GO:0045930 109 0.015
positive regulation of cell development GO:0010720 61 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
telencephalon development GO:0021537 2 0.015
protein phosphorylation GO:0006468 169 0.015
positive regulation of programmed cell death GO:0043068 62 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
neuron projection guidance GO:0097485 241 0.014
heterocycle catabolic process GO:0046700 166 0.014
mitotic spindle organization GO:0007052 220 0.014
intracellular protein transport GO:0006886 104 0.014
axon guidance GO:0007411 233 0.014
nitrogen compound transport GO:0071705 85 0.014
regulation of cysteine type endopeptidase activity GO:2000116 27 0.014
positive regulation of nervous system development GO:0051962 69 0.014
striated muscle tissue development GO:0014706 27 0.014
nucleocytoplasmic transport GO:0006913 72 0.013
regulation of intracellular protein transport GO:0033157 46 0.013
purine nucleoside monophosphate metabolic process GO:0009126 50 0.013
protein localization to nucleus GO:0034504 55 0.013
striated muscle myosin thick filament assembly GO:0071688 3 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
single organism nuclear import GO:1902593 51 0.013
regulation of double strand break repair GO:2000779 3 0.013
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.013
body morphogenesis GO:0010171 2 0.013
maternal determination of anterior posterior axis embryo GO:0008358 74 0.013
regulation of neurogenesis GO:0050767 158 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
small molecule metabolic process GO:0044281 305 0.013
eye development GO:0001654 323 0.013
tube morphogenesis GO:0035239 191 0.013
inositol lipid mediated signaling GO:0048017 4 0.013
chitin based larval cuticle pattern formation GO:0035293 11 0.013
single organism catabolic process GO:0044712 228 0.013
response to bacterium GO:0009617 198 0.012
developmental maturation GO:0021700 172 0.012
positive regulation of cell differentiation GO:0045597 64 0.012
regulation of catalytic activity GO:0050790 185 0.012
postreplication repair GO:0006301 2 0.012
positive regulation of histone deacetylation GO:0031065 2 0.012
protein transport GO:0015031 155 0.012
defense response GO:0006952 300 0.012
response to oxygen containing compound GO:1901700 200 0.012
embryonic axis specification GO:0000578 107 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
immune system process GO:0002376 347 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.012
larval development GO:0002164 104 0.011
regulation of behavior GO:0050795 75 0.011
protein processing GO:0016485 68 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
tripartite regional subdivision GO:0007351 103 0.011
regulation of defense response GO:0031347 102 0.011
chromatin assembly or disassembly GO:0006333 52 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
regulation of transport GO:0051049 181 0.011
non recombinational repair GO:0000726 7 0.011
defense response to bacterium GO:0042742 178 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
protein import into nucleus GO:0006606 51 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.010
endomembrane system organization GO:0010256 119 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
synapse organization GO:0050808 196 0.010
cell cycle checkpoint GO:0000075 95 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.010
regulation of cellular catabolic process GO:0031329 157 0.010

RpA-70 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
benign neoplasm DOID:0060072 0 0.035
disease of cellular proliferation DOID:14566 0 0.035