Drosophila melanogaster

156 known processes

Tl (Dmel_CG5490)

Toll

(Aliases: Fs(3)Tl,dToll,tl,mat(3)9,mel(3)10,Dmel\CG5490,mel(3)9,Toll-1,Toll1,T1,CG5490,dToll1,TL,CT17414,Fs(1)Tl,toll,toll-1)

Tl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 347 0.999
motor neuron axon guidance GO:0008045 58 0.999
regulation of immune effector process GO:0002697 52 0.998
regulation of antifungal peptide production GO:0002788 6 0.996
taxis GO:0042330 304 0.996
immune effector process GO:0002252 98 0.992
positive regulation of antifungal peptide production GO:0002804 6 0.991
regulation of humoral immune response GO:0002920 51 0.989
regulation of response to external stimulus GO:0032101 115 0.988
cellular amide metabolic process GO:0043603 80 0.987
humoral immune response GO:0006959 117 0.982
regulation of antimicrobial peptide production GO:0002784 44 0.981
neuron projection guidance GO:0097485 241 0.980
peptide metabolic process GO:0006518 80 0.979
regulation of defense response to fungus GO:1900150 6 0.971
hemocyte differentiation GO:0042386 38 0.970
antimicrobial humoral response GO:0019730 99 0.966
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.948
Mouse
tissue morphogenesis GO:0048729 297 0.948
immune response GO:0006955 246 0.938
antimicrobial peptide production GO:0002775 46 0.933
regulation of antifungal peptide biosynthetic process GO:0002810 5 0.931
response to virus GO:0009615 28 0.928
Zebrafish Mouse
regulation of multi organism process GO:0043900 131 0.928
cell motility GO:0048870 251 0.925
intracellular signal transduction GO:0035556 300 0.921
Mouse
axon guidance GO:0007411 233 0.920
positive regulation of signal transduction GO:0009967 223 0.918
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.905
Mouse
defense response to fungus GO:0050832 48 0.904
regulation of immune response GO:0050776 118 0.904
oocyte development GO:0048599 124 0.904
gastrulation GO:0007369 70 0.902
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.891
embryonic hemopoiesis GO:0035162 26 0.887
regulation of developmental growth GO:0048638 174 0.883
production of molecular mediator of immune response GO:0002440 46 0.877
regulation of cellular amide metabolic process GO:0034248 39 0.833
phosphorylation GO:0016310 294 0.831
Mouse
chemotaxis GO:0006935 249 0.823
oocyte axis specification GO:0007309 108 0.792
regulation of response to biotic stimulus GO:0002831 63 0.790
defense response GO:0006952 300 0.785
positive regulation of gene expression GO:0010628 290 0.783
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.768
Mouse
mesoderm morphogenesis GO:0048332 22 0.762
hemopoiesis GO:0030097 46 0.760
oocyte differentiation GO:0009994 145 0.758
regionalization GO:0003002 416 0.757
positive regulation of transcription dna templated GO:0045893 266 0.740
Mouse
protein localization to nucleus GO:0034504 55 0.734
negative regulation of signaling GO:0023057 219 0.719
cellular response to chemical stimulus GO:0070887 199 0.692
immune response activating signal transduction GO:0002757 2 0.686
Mouse
antifungal humoral response GO:0019732 12 0.686
larval lymph gland hemopoiesis GO:0035167 17 0.674
dorsal ventral pattern formation GO:0009953 133 0.671
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.666
embryonic development via the syncytial blastoderm GO:0001700 148 0.645
bmp signaling pathway GO:0030509 27 0.641
positive regulation of response to stimulus GO:0048584 323 0.634
response to nitrogen compound GO:1901698 90 0.627
Mouse
synapse assembly GO:0007416 143 0.613
protein complex localization GO:0031503 4 0.611
regulation of immune system process GO:0002682 176 0.576
formation of primary germ layer GO:0001704 24 0.571
peptide biosynthetic process GO:0043043 42 0.551
positive regulation of intracellular signal transduction GO:1902533 116 0.549
Mouse
axonogenesis GO:0007409 290 0.539
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.537
Mouse
innate immune response GO:0045087 144 0.533
positive regulation of multicellular organismal process GO:0051240 143 0.527
Mouse
positive regulation of phosphate metabolic process GO:0045937 139 0.527
Mouse
oocyte construction GO:0007308 112 0.523
ribonucleoside metabolic process GO:0009119 127 0.522
regulation of production of molecular mediator of immune response GO:0002700 44 0.522
regulation of cell differentiation GO:0045595 302 0.511
regulation of nf kappab import into nucleus GO:0042345 1 0.500
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.488
positive regulation of nucleic acid templated transcription GO:1903508 266 0.488
Mouse
localization of cell GO:0051674 257 0.488
negative regulation of cell communication GO:0010648 223 0.483
positive regulation of signaling GO:0023056 243 0.476
Mouse
embryonic organ development GO:0048568 50 0.467
regulation of cell morphogenesis GO:0022604 163 0.467
endodermal cell differentiation GO:0035987 3 0.464
neuromuscular junction development GO:0007528 149 0.456
guanosine containing compound metabolic process GO:1901068 74 0.446
determination of dorsal ventral asymmetry GO:0048262 3 0.441
protein targeting to nucleus GO:0044744 51 0.439
regulation of protein transport GO:0051223 57 0.435
cell maturation GO:0048469 144 0.433
regulation of localization GO:0032879 275 0.426
digestive system development GO:0055123 149 0.425
regulation of hemocyte differentiation GO:0045610 22 0.423
negative regulation of signal transduction GO:0009968 206 0.414
cell migration GO:0016477 238 0.411
embryonic heart tube development GO:0035050 22 0.408
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.407
Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.399
Mouse
amide biosynthetic process GO:0043604 42 0.396
axis specification GO:0009798 167 0.381
forebrain development GO:0030900 2 0.380
torso signaling pathway GO:0008293 21 0.376
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.375
anterior posterior axis specification embryo GO:0008595 103 0.375
single organism cellular localization GO:1902580 180 0.372
positive regulation of antimicrobial peptide production GO:0002225 28 0.369
positive regulation of bmp signaling pathway GO:0030513 5 0.366
mesoderm formation GO:0001707 21 0.359
imaginal disc derived wing morphogenesis GO:0007476 337 0.357
post embryonic hemopoiesis GO:0035166 17 0.356
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.351
immune system development GO:0002520 57 0.343
regulation of cuticle pigmentation GO:0048079 16 0.341
cell division GO:0051301 248 0.339
response to external biotic stimulus GO:0043207 293 0.338
tube development GO:0035295 244 0.336
regulation of cholesterol transport GO:0032374 1 0.326
protein transport GO:0015031 155 0.323
apoptotic signaling pathway GO:0097190 27 0.316
post embryonic appendage morphogenesis GO:0035120 385 0.315
activation of innate immune response GO:0002218 4 0.315
Mouse
heart development GO:0007507 82 0.309
striated muscle tissue development GO:0014706 27 0.304
positive regulation of cell communication GO:0010647 250 0.301
Mouse
blastoderm segmentation GO:0007350 159 0.296
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.296
regulation of intracellular signal transduction GO:1902531 236 0.294
Mouse
organonitrogen compound metabolic process GO:1901564 318 0.293
axon development GO:0061564 297 0.292
regulation of intracellular protein transport GO:0033157 46 0.288
protein localization GO:0008104 284 0.288
single organism nuclear import GO:1902593 51 0.284
regulation of catabolic process GO:0009894 170 0.282
regulation of bmp signaling pathway GO:0030510 23 0.280
positive regulation of cellular component biogenesis GO:0044089 80 0.278
i kappab kinase nf kappab signaling GO:0007249 6 0.274
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 179 0.273
purine nucleoside catabolic process GO:0006152 112 0.271
pattern recognition receptor signaling pathway GO:0002221 2 0.269
Mouse
embryonic morphogenesis GO:0048598 206 0.268
protein import GO:0017038 55 0.261
digestive tract morphogenesis GO:0048546 127 0.260
synaptic growth at neuromuscular junction GO:0051124 119 0.256
segmentation GO:0035282 207 0.254
regulation of developmental pigmentation GO:0048070 24 0.254
regulation of response to stress GO:0080134 200 0.248
morphogenesis of embryonic epithelium GO:0016331 94 0.246
cellular macromolecule localization GO:0070727 220 0.246
carbohydrate derivative metabolic process GO:1901135 217 0.244
Fly
negative regulation of nf kappab import into nucleus GO:0042347 1 0.241
protein import into nucleus GO:0006606 51 0.240
nucleoside catabolic process GO:0009164 112 0.236
regulation of multicellular organismal development GO:2000026 414 0.235
glycosyl compound catabolic process GO:1901658 112 0.233
regulation of response to wounding GO:1903034 19 0.233
Mouse
nuclear import GO:0051170 51 0.232
positive regulation of biosynthetic process GO:0009891 316 0.232
negative regulation of multicellular organismal process GO:0051241 142 0.222
Mouse
nucleocytoplasmic transport GO:0006913 72 0.218
cardiac cell fate commitment GO:0060911 17 0.214
neuron recognition GO:0008038 101 0.213
purine ribonucleoside catabolic process GO:0046130 112 0.211
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.209
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.209
regulation of cell migration GO:0030334 22 0.208
central nervous system development GO:0007417 201 0.207
regulation of phosphate metabolic process GO:0019220 210 0.206
Mouse
protein modification process GO:0036211 438 0.205
Fly
positive regulation of defense response GO:0031349 59 0.204
guanosine containing compound catabolic process GO:1901069 74 0.204
regulation of cell motility GO:2000145 23 0.201
regulation of anatomical structure morphogenesis GO:0022603 242 0.200
digestive tract development GO:0048565 149 0.199
dendrite morphogenesis GO:0048813 199 0.197
protein phosphorylation GO:0006468 169 0.192
protein targeting GO:0006605 64 0.191
response to endogenous stimulus GO:0009719 119 0.188
antifungal peptide biosynthetic process GO:0002783 5 0.188
morphogenesis of an epithelium GO:0002009 276 0.186
developmental maturation GO:0021700 172 0.184
regulation of nervous system development GO:0051960 248 0.182
regulation of catalytic activity GO:0050790 185 0.181
muscle structure development GO:0061061 224 0.181
regulation of cellular localization GO:0060341 136 0.179
positive regulation of immune effector process GO:0002699 28 0.178
endodermal cell fate commitment GO:0001711 3 0.176
positive regulation of phosphorylation GO:0042327 87 0.175
Mouse
carbohydrate derivative catabolic process GO:1901136 118 0.174
gtp metabolic process GO:0046039 72 0.174
response to biotic stimulus GO:0009607 294 0.174
regulation of protein import into nucleus GO:0042306 28 0.172
dorsal closure GO:0007391 79 0.171
mesoderm development GO:0007498 78 0.169
regulation of autophagy GO:0010506 62 0.169
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.168
cell proliferation involved in imaginal disc derived wing morphogenesis GO:0090255 2 0.167
antibacterial humoral response GO:0019731 44 0.167
regulation of phosphorylation GO:0042325 147 0.164
Mouse
positive regulation of cell motility GO:2000147 3 0.163
regulation of cytoplasmic transport GO:1903649 47 0.163
cell proliferation GO:0008283 299 0.161
hematopoietic or lymphoid organ development GO:0048534 57 0.160
tripartite regional subdivision GO:0007351 103 0.159
establishment of protein localization GO:0045184 163 0.159
response to fungus GO:0009620 50 0.159
regulation of phosphorus metabolic process GO:0051174 210 0.158
Mouse
cytoplasmic transport GO:0016482 130 0.157
wing disc morphogenesis GO:0007472 344 0.155
defense response to other organism GO:0098542 225 0.155
female meiotic division GO:0007143 70 0.153
regulation of protein kinase activity GO:0045859 51 0.153
response to growth factor GO:0070848 31 0.149
regulation of cell development GO:0060284 215 0.148
nuclear transport GO:0051169 72 0.146
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.145
imaginal disc derived appendage development GO:0048737 399 0.144
i kappab phosphorylation GO:0007252 3 0.141
regulation of kinase activity GO:0043549 53 0.138
intracellular protein transport GO:0006886 104 0.137
regulation of growth GO:0040008 233 0.136
positive regulation of response to external stimulus GO:0032103 44 0.134
purine ribonucleoside metabolic process GO:0046128 127 0.133
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.131
regulation of establishment of protein localization GO:0070201 61 0.131
stem cell division GO:0017145 69 0.129
gonad development GO:0008406 50 0.127
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.125
development of primary sexual characteristics GO:0045137 50 0.125
antimicrobial peptide biosynthetic process GO:0002777 38 0.125
regulation of transport GO:0051049 181 0.125
positive regulation of growth GO:0045927 75 0.121
extrinsic apoptotic signaling pathway GO:0097191 1 0.121
cell activation GO:0001775 9 0.119
Mouse
determination of ventral identity GO:0048264 1 0.118
connective tissue development GO:0061448 3 0.116
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.115
Mouse
renal tubule development GO:0061326 64 0.113
peripheral nervous system development GO:0007422 52 0.110
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.108
Mouse
inositol lipid mediated signaling GO:0048017 4 0.108
positive regulation of cellular component organization GO:0051130 156 0.105
ribonucleoside catabolic process GO:0042454 112 0.103
catabolic process GO:0009056 409 0.102
nf kappab import into nucleus GO:0042348 1 0.101
negative regulation of immune system process GO:0002683 50 0.101
gtp catabolic process GO:0006184 72 0.101
regulation of cell junction assembly GO:1901888 2 0.100
organic acid metabolic process GO:0006082 103 0.100
carboxylic acid metabolic process GO:0019752 92 0.099
response to osmotic stress GO:0006970 14 0.099
organonitrogen compound biosynthetic process GO:1901566 117 0.098
cellular protein localization GO:0034613 160 0.095
pathway restricted smad protein phosphorylation GO:0060389 1 0.094
purine nucleoside metabolic process GO:0042278 127 0.094
activation of protein kinase activity GO:0032147 12 0.093
regulation of nucleocytoplasmic transport GO:0046822 35 0.092
regulation of neurogenesis GO:0050767 158 0.091
regulation of innate immune response GO:0045088 71 0.091
Mouse
stress activated mapk cascade GO:0051403 52 0.088
Mouse
regulation of cellular catabolic process GO:0031329 157 0.088
melanotic encapsulation of foreign target GO:0035011 30 0.088
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.085
immune response regulating signaling pathway GO:0002764 2 0.085
Mouse
positive regulation of molecular function GO:0044093 136 0.085
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 108 0.085
anterior posterior axis specification GO:0009948 109 0.085
regulation of protein modification process GO:0031399 112 0.085
Fly
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.084
regulation of protein localization GO:0032880 76 0.082
negative regulation of autophagy GO:0010507 16 0.081
dorsal ventral axis specification GO:0009950 66 0.080
positive regulation of phosphorus metabolic process GO:0010562 139 0.079
Mouse
malpighian tubule development GO:0072002 64 0.077
regulation of protein targeting GO:1903533 29 0.077
head development GO:0060322 135 0.077
regulation of organ morphogenesis GO:2000027 78 0.077
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.076
positive regulation of cell adhesion GO:0045785 10 0.074
unidimensional cell growth GO:0009826 15 0.072
germ cell migration GO:0008354 43 0.072
regulation of intracellular transport GO:0032386 64 0.072
positive regulation of cellular catabolic process GO:0031331 95 0.071
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.071
small molecule metabolic process GO:0044281 305 0.071
positive regulation of developmental growth GO:0048639 62 0.070
cell cycle g1 s phase transition GO:0044843 31 0.070
secondary metabolic process GO:0019748 75 0.069
dephosphorylation GO:0016311 51 0.068
establishment of protein localization to organelle GO:0072594 62 0.067
anterior posterior pattern specification imaginal disc GO:0007448 16 0.066
developmental growth GO:0048589 280 0.066
regulation of programmed cell death GO:0043067 152 0.066
retinal ganglion cell axon guidance GO:0031290 12 0.066
organophosphate metabolic process GO:0019637 195 0.065
endoderm formation GO:0001706 3 0.065
positive regulation of immune system process GO:0002684 68 0.065
positive regulation of protein metabolic process GO:0051247 128 0.064
Mouse
nucleoside triphosphate metabolic process GO:0009141 120 0.064
cellular response to endogenous stimulus GO:0071495 80 0.064
cell rearrangement involved in malpighian tubule morphogenesis GO:0061334 3 0.062
actin cytoskeleton organization GO:0030036 206 0.062
hindgut morphogenesis GO:0007442 58 0.062
regulation of locomotion GO:0040012 42 0.062
purine containing compound metabolic process GO:0072521 155 0.062
imaginal disc pattern formation GO:0007447 91 0.061
regulation of epithelial cell migration GO:0010632 12 0.061
hematopoietic progenitor cell differentiation GO:0002244 1 0.061
negative regulation of cell death GO:0060548 81 0.060
cell fate determination GO:0001709 91 0.060
antifungal peptide production GO:0002781 7 0.059
instar larval development GO:0002168 55 0.057
positive regulation of secretion GO:0051047 22 0.057
pigment metabolic process GO:0042440 84 0.057
cellular amino acid metabolic process GO:0006520 61 0.056
defense response to bacterium GO:0042742 178 0.056
membrane organization GO:0061024 112 0.054
negative regulation of lipid storage GO:0010888 3 0.054
regulation of apoptotic process GO:0042981 130 0.053
regulation of jun kinase activity GO:0043506 8 0.053
regulation of cell projection organization GO:0031344 92 0.053
regulation of hydrolase activity GO:0051336 97 0.053
positive regulation of protein localization to nucleus GO:1900182 21 0.052
cellular response to organic substance GO:0071310 132 0.052
organic substance transport GO:0071702 257 0.052
positive regulation of protein import into nucleus GO:0042307 21 0.052
positive regulation of cell differentiation GO:0045597 64 0.052
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.052
positive regulation of developmental process GO:0051094 143 0.052
convergent extension GO:0060026 2 0.051
regulation of cell cell adhesion GO:0022407 21 0.051
regulation of cell proliferation GO:0042127 163 0.051
regulation of dendrite development GO:0050773 37 0.050
chorion containing eggshell pattern formation GO:0030381 11 0.050
chromatin modification GO:0016568 147 0.050
mapk cascade GO:0000165 107 0.049
Mouse
oxoacid metabolic process GO:0043436 103 0.049
body morphogenesis GO:0010171 2 0.048
Worm
negative regulation of synapse assembly GO:0051964 39 0.048
positive regulation of macromolecule metabolic process GO:0010604 405 0.048
Mouse
regulation of transferase activity GO:0051338 58 0.048
cellular response to growth factor stimulus GO:0071363 30 0.047
positive regulation of nervous system development GO:0051962 69 0.047
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.047
negative regulation of apoptotic process GO:0043066 63 0.047
positive regulation of mapk cascade GO:0043410 63 0.046
Mouse
positive regulation of jun kinase activity GO:0043507 4 0.046
positive regulation of response to biotic stimulus GO:0002833 31 0.046
positive regulation of cell migration GO:0030335 2 0.046
stem cell proliferation GO:0072089 88 0.046
positive regulation of intracellular transport GO:0032388 42 0.045
adult locomotory behavior GO:0008344 76 0.044
neuroblast division GO:0055057 35 0.044
autophagy GO:0006914 108 0.044
dendrite development GO:0016358 204 0.044
larval development GO:0002164 104 0.044
Worm
gland development GO:0048732 191 0.044
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.044
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.043
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.043
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.043
regulation of cellular component movement GO:0051270 42 0.042
response to uv GO:0009411 24 0.042
regulation of reproductive process GO:2000241 54 0.041
embryonic pattern specification GO:0009880 174 0.041
cell elongation involved in imaginal disc derived wing morphogenesis GO:0090254 5 0.041
jak stat cascade GO:0007259 49 0.041
determination of bilateral symmetry GO:0009855 13 0.040
positive regulation of protein transport GO:0051222 37 0.040
tor signaling GO:0031929 32 0.040
signal transduction by phosphorylation GO:0023014 107 0.040
Mouse
jnk cascade GO:0007254 50 0.040
Mouse
positive regulation of cell size GO:0045793 21 0.040
embryo development ending in birth or egg hatching GO:0009792 152 0.039
Worm
cell projection assembly GO:0030031 94 0.039
cellular protein modification process GO:0006464 438 0.039
Fly
regulation of jnk cascade GO:0046328 40 0.038
Mouse
cellular lipid metabolic process GO:0044255 83 0.038
negative regulation of wnt signaling pathway GO:0030178 28 0.038
purine nucleoside triphosphate metabolic process GO:0009144 119 0.037
nucleotide metabolic process GO:0009117 161 0.037
embryonic axis specification GO:0000578 107 0.037
positive regulation of catabolic process GO:0009896 105 0.037
peptidyl threonine modification GO:0018210 3 0.036
regulation of stress activated mapk cascade GO:0032872 41 0.036
Mouse
mitochondrion organization GO:0007005 65 0.036
regulation of lipid transport GO:0032368 3 0.036
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.036
peptidyl amino acid modification GO:0018193 105 0.036
purine ribonucleotide metabolic process GO:0009150 145 0.035
negative regulation of programmed cell death GO:0043069 72 0.035
negative regulation of cell cell adhesion GO:0022408 8 0.035
purine containing compound catabolic process GO:0072523 112 0.035
cardiocyte differentiation GO:0035051 29 0.035
positive regulation of protein kinase activity GO:0045860 25 0.035
nucleoside metabolic process GO:0009116 127 0.035
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.035
compound eye development GO:0048749 307 0.034
wing disc anterior posterior pattern formation GO:0048100 5 0.034
mitotic spindle organization GO:0007052 220 0.034
nucleobase containing small molecule metabolic process GO:0055086 174 0.034
positive regulation of immune response GO:0050778 63 0.033
brain development GO:0007420 120 0.033
regulation of transcription factor import into nucleus GO:0042990 22 0.033
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.033
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.033
cardiac cell fate determination GO:0060913 3 0.033
negative regulation of cellular component organization GO:0051129 108 0.033
head involution GO:0008258 35 0.033
response to lipopolysaccharide GO:0032496 4 0.032
regulation of cell death GO:0010941 173 0.032
regulation of membrane potential GO:0042391 35 0.032
regulation of neuron differentiation GO:0045664 103 0.032
nucleobase containing compound catabolic process GO:0034655 165 0.032
negative regulation of response to stimulus GO:0048585 258 0.032
tube morphogenesis GO:0035239 191 0.032
encapsulation of foreign target GO:0035010 38 0.031
pole plasm mrna localization GO:0019094 49 0.031
regulation of cell adhesion GO:0030155 27 0.031
bmp signaling pathway involved in malpighian tubule cell chemotaxis GO:0061353 3 0.031
activation of immune response GO:0002253 5 0.031
Mouse
purine ribonucleotide catabolic process GO:0009154 109 0.030
single organism carbohydrate metabolic process GO:0044723 72 0.030
Fly
regulation of synaptic transmission GO:0050804 69 0.030
regulation of protein complex assembly GO:0043254 42 0.030
endocytosis GO:0006897 310 0.029
exocrine system development GO:0035272 162 0.029
vesicle mediated transport GO:0016192 381 0.029
carbohydrate metabolic process GO:0005975 82 0.029
Fly
regulation of synapse assembly GO:0051963 94 0.028
single organism catabolic process GO:0044712 228 0.028
negative regulation of rna biosynthetic process GO:1902679 240 0.028
salivary gland development GO:0007431 162 0.028
oocyte microtubule cytoskeleton organization GO:0016325 35 0.027
glycosyl compound metabolic process GO:1901657 127 0.027
muscle cell fate specification GO:0042694 7 0.027
positive regulation of humoral immune response GO:0002922 28 0.027
establishment of localization in cell GO:0051649 402 0.027
ectodermal placode formation GO:0060788 4 0.027
positive regulation of protein complex assembly GO:0031334 22 0.027
regulation of apoptotic signaling pathway GO:2001233 10 0.027
neuroblast proliferation GO:0007405 74 0.027
regulation of cell proliferation involved in imaginal disc derived wing morphogenesis GO:0090256 2 0.026
adult chitin containing cuticle pigmentation GO:0048085 16 0.026
positive regulation of lipid metabolic process GO:0045834 4 0.026
positive regulation of synapse assembly GO:0051965 29 0.026
regulation of cell size GO:0008361 63 0.026
cell adhesion GO:0007155 136 0.026
Fly
antibacterial peptide biosynthetic process GO:0002780 22 0.026
positive regulation of gtpase activity GO:0043547 43 0.026
response to wounding GO:0009611 94 0.025
Mouse
regulation of cellular amine metabolic process GO:0033238 3 0.025
ribonucleoside triphosphate metabolic process GO:0009199 119 0.025
regulation of axonogenesis GO:0050770 32 0.025
cell cycle phase transition GO:0044770 140 0.025
purine nucleotide metabolic process GO:0006163 146 0.025
ribonucleoprotein complex disassembly GO:0032988 1 0.025
maintenance of protein location in cell GO:0032507 26 0.025
negative regulation of rna metabolic process GO:0051253 251 0.024
negative regulation of cell differentiation GO:0045596 143 0.024
trunk segmentation GO:0035290 8 0.024
eye antennal disc development GO:0035214 60 0.024
positive regulation of hydrolase activity GO:0051345 78 0.024
adherens junction assembly GO:0034333 11 0.024
growth GO:0040007 359 0.024
muscle cell fate commitment GO:0042693 14 0.024
specification of symmetry GO:0009799 13 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.023
organophosphate catabolic process GO:0046434 112 0.023
melanization defense response GO:0035006 45 0.023
purine nucleotide catabolic process GO:0006195 109 0.023
regulation of protein phosphorylation GO:0001932 64 0.022
proteolysis GO:0006508 192 0.022
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.022
pole plasm rna localization GO:0007316 52 0.022
appendage morphogenesis GO:0035107 397 0.022
enteroendocrine cell differentiation GO:0035883 1 0.022
death GO:0016265 284 0.022
biological adhesion GO:0022610 138 0.022
Fly
regulation of molecular function GO:0065009 217 0.022
Mouse
negative regulation of cell cycle process GO:0010948 109 0.022
regulation of ion transport GO:0043269 39 0.021
gland morphogenesis GO:0022612 145 0.021
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.021
regulation of nucleotide catabolic process GO:0030811 48 0.021
regulation of defense response GO:0031347 102 0.021
mesenchymal cell differentiation GO:0048762 1 0.021
tissue homeostasis GO:0001894 36 0.021
Mouse
chaeta development GO:0022416 97 0.021
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.021

Tl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.071
disease of cellular proliferation DOID:14566 0 0.071
organ system cancer DOID:0050686 0 0.039
disease of anatomical entity DOID:7 0 0.027
familial meningioma DOID:4586 0 0.027
nervous system cancer DOID:3093 0 0.027
central nervous system cancer DOID:3620 0 0.027
meningioma DOID:3565 0 0.027