Drosophila melanogaster

52 known processes

CoVa (Dmel_CG14724)

Cytochrome c oxidase subunit Va

(Aliases: Va,COX,tend,Dmel\CG14724,COXA_DROME,CG14724)

CoVa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 143 0.264
Worm
nucleobase containing small molecule metabolic process GO:0055086 174 0.262
Worm
determination of adult lifespan GO:0008340 137 0.210
Worm
nucleoside triphosphate metabolic process GO:0009141 120 0.205
Worm
embryo development ending in birth or egg hatching GO:0009792 152 0.168
Worm
growth GO:0040007 359 0.147
multicellular organismal aging GO:0010259 140 0.136
Worm
death GO:0016265 284 0.123
vesicle mediated transport GO:0016192 381 0.120
macromolecular complex assembly GO:0065003 256 0.118
protein complex biogenesis GO:0070271 201 0.117
endocytosis GO:0006897 310 0.111
defense response GO:0006952 300 0.107
establishment of localization in cell GO:0051649 402 0.101
immune response GO:0006955 246 0.095
ribose phosphate metabolic process GO:0019693 145 0.091
Worm
phosphorylation GO:0016310 294 0.090
Worm
ribonucleotide metabolic process GO:0009259 145 0.086
Worm
purine containing compound metabolic process GO:0072521 155 0.071
Worm
response to other organism GO:0051707 293 0.070
programmed cell death GO:0012501 257 0.064
purine nucleoside triphosphate metabolic process GO:0009144 119 0.061
Worm
organophosphate metabolic process GO:0019637 195 0.061
Worm
cell death GO:0008219 279 0.059
nucleoside metabolic process GO:0009116 127 0.054
Worm
positive regulation of biosynthetic process GO:0009891 316 0.053
nucleotide metabolic process GO:0009117 161 0.051
Worm
innate immune response GO:0045087 144 0.049
small molecule metabolic process GO:0044281 305 0.048
Worm
ribonucleoside monophosphate metabolic process GO:0009161 51 0.048
Worm
glycosyl compound metabolic process GO:1901657 127 0.046
Worm
carbohydrate derivative metabolic process GO:1901135 217 0.043
Worm
cell proliferation GO:0008283 299 0.043
central nervous system development GO:0007417 201 0.042
Zebrafish
ribose phosphate biosynthetic process GO:0046390 28 0.041
intracellular signal transduction GO:0035556 300 0.039
purine ribonucleoside metabolic process GO:0046128 127 0.039
Worm
response to biotic stimulus GO:0009607 294 0.037
organonitrogen compound metabolic process GO:1901564 318 0.037
Worm
purine ribonucleotide metabolic process GO:0009150 145 0.036
Worm
single organism intracellular transport GO:1902582 207 0.035
nucleoside phosphate metabolic process GO:0006753 162 0.035
Worm
brain development GO:0007420 120 0.035
purine nucleotide metabolic process GO:0006163 146 0.033
Worm
apoptotic process GO:0006915 159 0.033
regulation of catalytic activity GO:0050790 185 0.032
ribonucleoside triphosphate metabolic process GO:0009199 119 0.031
Worm
ribonucleoside metabolic process GO:0009119 127 0.030
Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.030
Worm
larval development GO:0002164 104 0.028
Worm
nucleoside monophosphate metabolic process GO:0009123 52 0.028
Worm
regulation of intracellular signal transduction GO:1902531 236 0.027
endomembrane system organization GO:0010256 119 0.027
regulation of molecular function GO:0065009 217 0.027
negative regulation of response to stimulus GO:0048585 258 0.025
ion transport GO:0006811 145 0.025
Zebrafish
regulation of multicellular organismal development GO:2000026 414 0.025
ion transmembrane transport GO:0034220 122 0.025
Zebrafish
protein complex assembly GO:0006461 200 0.025
response to external biotic stimulus GO:0043207 293 0.024
atp metabolic process GO:0046034 49 0.023
Worm
intracellular transport GO:0046907 228 0.023
negative regulation of cell death GO:0060548 81 0.022
purine nucleoside monophosphate metabolic process GO:0009126 50 0.022
Worm
negative regulation of cellular metabolic process GO:0031324 382 0.022
immune system process GO:0002376 347 0.022
regulation of atpase activity GO:0043462 4 0.021
cation transmembrane transport GO:0098655 88 0.021
Zebrafish
regulation of hydrolase activity GO:0051336 97 0.020
positive regulation of viral process GO:0048524 2 0.020
regulation of growth GO:0040008 233 0.020
phagocytosis GO:0006909 215 0.020
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
response to nitrogen compound GO:1901698 90 0.019
base excision repair GO:0006284 2 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
regulation of developmental growth GO:0048638 174 0.018
negative regulation of programmed cell death GO:0043069 72 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.017
monovalent inorganic cation transport GO:0015672 40 0.017
Zebrafish
regulation of cell death GO:0010941 173 0.017
energy derivation by oxidation of organic compounds GO:0015980 32 0.017
Worm
negative regulation of multicellular organismal process GO:0051241 142 0.016
response to bacterium GO:0009617 198 0.016
negative regulation of gene expression GO:0010629 387 0.016
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
electron transport chain GO:0022900 14 0.016
Worm
response to oxygen containing compound GO:1901700 200 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.016
single organism biosynthetic process GO:0044711 206 0.016
negative regulation of signal transduction GO:0009968 206 0.015
defense response to other organism GO:0098542 225 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
response to organophosphorus GO:0046683 2 0.015
transmembrane transport GO:0055085 139 0.014
Zebrafish
generation of precursor metabolites and energy GO:0006091 42 0.014
Worm
hematopoietic stem cell differentiation GO:0060218 1 0.014
cellular respiration GO:0045333 26 0.014
Worm
negative regulation of neuron projection development GO:0010977 9 0.014
cellular protein complex assembly GO:0043623 71 0.014
inorganic ion transmembrane transport GO:0098660 73 0.014
Zebrafish
developmental growth GO:0048589 280 0.014
body morphogenesis GO:0010171 2 0.014
organelle inheritance GO:0048308 2 0.014
regulation of phosphatase activity GO:0010921 3 0.013
response to oxygen levels GO:0070482 59 0.013
protein phosphorylation GO:0006468 169 0.013
cation transport GO:0006812 110 0.013
Zebrafish
purine nucleoside metabolic process GO:0042278 127 0.013
Worm
regulation of protein metabolic process GO:0051246 256 0.013
regulation of response to stress GO:0080134 200 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
regulation of mrna processing GO:0050684 71 0.013
regulation of nervous system development GO:0051960 248 0.012
oxidation reduction process GO:0055114 123 0.012
Zebrafish Worm
response to abiotic stimulus GO:0009628 341 0.012
negative regulation of transcription factor import into nucleus GO:0042992 4 0.011
response to organic substance GO:0010033 284 0.011
regulation of cell development GO:0060284 215 0.011
purine containing compound biosynthetic process GO:0072522 30 0.011
ribonucleoprotein complex disassembly GO:0032988 1 0.011
regulation of programmed cell death GO:0043067 152 0.011
regulation of apoptotic process GO:0042981 130 0.011
regulation of cell differentiation GO:0045595 302 0.011
positive regulation of molecular function GO:0044093 136 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
regulation of hemocyte proliferation GO:0035206 37 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.010
Worm
positive regulation of binding GO:0051099 4 0.010
negative regulation of developmental process GO:0051093 201 0.010
negative regulation of nervous system development GO:0051961 92 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010
negative regulation of nucleic acid templated transcription GO:1903507 240 0.010
regulation of phosphorylation GO:0042325 147 0.010
regulation of signal transduction by p53 class mediator GO:1901796 1 0.010
inorganic cation transmembrane transport GO:0098662 61 0.010
Zebrafish

CoVa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.058
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
myeloid leukemia DOID:8692 0 0.014
immune system cancer DOID:0060083 0 0.014
hematologic cancer DOID:2531 0 0.014
leukemia DOID:1240 0 0.014
organ system cancer DOID:0050686 0 0.014