Drosophila melanogaster

130 known processes

orb (Dmel_CG10868)

oo18 RNA-binding protein

(Aliases: Orb,CG10868,oo18,151666_s_at,Dmel\CG10868,fs(3)00107,ORB)

orb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axis specification GO:0009798 167 0.982
ovarian follicle cell development GO:0030707 248 0.974
regulation of pole plasm oskar mrna localization GO:0007317 27 0.971
oocyte development GO:0048599 124 0.967
anterior posterior axis specification GO:0009948 109 0.961
germarium derived oocyte fate determination GO:0007294 26 0.961
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.954
anterior posterior pattern specification GO:0009952 136 0.927
columnar cuboidal epithelial cell development GO:0002066 249 0.923
regulation of oocyte development GO:0060281 27 0.915
chorion containing eggshell formation GO:0007304 105 0.885
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.881
blastoderm segmentation GO:0007350 159 0.880
oocyte differentiation GO:0009994 145 0.863
eggshell chorion assembly GO:0007306 66 0.835
oocyte axis specification GO:0007309 108 0.829
pole plasm oskar mrna localization GO:0045451 46 0.825
germarium derived egg chamber formation GO:0007293 101 0.817
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.810
oocyte construction GO:0007308 112 0.786
intracellular mrna localization GO:0008298 66 0.745
regulation of cell cycle GO:0051726 291 0.717
oocyte microtubule cytoskeleton organization GO:0016325 35 0.698
embryonic axis specification GO:0000578 107 0.697
regulation of cell cycle process GO:0010564 181 0.695
germarium derived oocyte differentiation GO:0030706 29 0.665
oocyte anterior posterior axis specification GO:0007314 72 0.662
epithelial cell development GO:0002064 274 0.629
dorsal appendage formation GO:0046843 47 0.622
karyosome formation GO:0030717 22 0.621
anterior posterior axis specification embryo GO:0008595 103 0.614
eggshell formation GO:0030703 105 0.606
regulation of mitotic cell cycle GO:0007346 190 0.561
segmentation GO:0035282 207 0.556
oocyte maturation GO:0001556 3 0.537
epithelial cell differentiation GO:0030855 322 0.499
regulation of cell cycle phase transition GO:1901987 130 0.464
pole plasm assembly GO:0007315 61 0.461
pole plasm protein localization GO:0007318 10 0.458
cell maturation GO:0048469 144 0.431
positive regulation of macromolecule metabolic process GO:0010604 405 0.425
regionalization GO:0003002 416 0.405
cell cycle phase transition GO:0044770 140 0.399
negative regulation of cellular biosynthetic process GO:0031327 277 0.363
Mouse
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.329
regulation of cellular protein metabolic process GO:0032268 243 0.326
oocyte dorsal ventral axis specification GO:0007310 34 0.325
rna localization GO:0006403 115 0.322
cellular component assembly involved in morphogenesis GO:0010927 151 0.318
oocyte fate determination GO:0030716 27 0.317
regulation of embryonic pattern specification GO:1902875 27 0.311
regulation of embryonic development GO:0045995 68 0.306
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.304
embryonic pattern specification GO:0009880 174 0.303
negative regulation of cellular metabolic process GO:0031324 382 0.301
Mouse
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.301
regulation of dna metabolic process GO:0051052 34 0.281
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.278
negative regulation of biosynthetic process GO:0009890 277 0.275
Mouse
pole plasm rna localization GO:0007316 52 0.274
posttranscriptional gene silencing GO:0016441 46 0.273
developmental maturation GO:0021700 172 0.263
mitotic nuclear division GO:0007067 213 0.252
chromosome segregation GO:0007059 157 0.252
g2 m transition of mitotic cell cycle GO:0000086 19 0.226
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.217
regulation of protein metabolic process GO:0051246 256 0.215
negative regulation of oskar mrna translation GO:0007319 5 0.213
regulation of mitotic cell cycle phase transition GO:1901990 130 0.209
tripartite regional subdivision GO:0007351 103 0.208
negative regulation of cell cycle process GO:0010948 109 0.192
negative regulation of nucleic acid templated transcription GO:1903507 240 0.184
positive regulation of mrna catabolic process GO:0061014 5 0.177
regulation of immune system process GO:0002682 176 0.163
targeting of mrna for destruction involved in rna interference GO:0030423 4 0.156
pole plasm mrna localization GO:0019094 49 0.154
dna geometric change GO:0032392 16 0.154
cell proliferation GO:0008283 299 0.153
dna metabolic process GO:0006259 227 0.151
positive regulation of biosynthetic process GO:0009891 316 0.150
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 4 0.148
vitelline membrane formation GO:0030704 11 0.144
cell fate determination GO:0001709 91 0.142
negative regulation of cell cycle GO:0045786 116 0.142
regulation of cell maturation GO:1903429 27 0.141
mitotic dna integrity checkpoint GO:0044774 75 0.141
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.138
chromosome organization GO:0051276 360 0.138
Mouse
recombinational repair GO:0000725 13 0.138
posttranscriptional gene silencing by rna GO:0035194 45 0.137
male gamete generation GO:0048232 201 0.136
gene silencing GO:0016458 138 0.133
immune system process GO:0002376 347 0.130
positive regulation of cellular biosynthetic process GO:0031328 316 0.130
proteolysis GO:0006508 192 0.129
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.128
translation GO:0006412 69 0.128
meiotic sister chromatid segregation GO:0045144 6 0.124
response to other organism GO:0051707 293 0.122
positive regulation of gene expression GO:0010628 290 0.120
organelle fission GO:0048285 340 0.120
Mouse
dorsal ventral pattern formation GO:0009953 133 0.119
polarity specification of dorsal ventral axis GO:0009951 6 0.119
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.117
nuclear division GO:0000280 332 0.116
Mouse
meiotic chromosome segregation GO:0045132 59 0.116
sex determination GO:0007530 18 0.115
negative regulation of transposition GO:0010529 12 0.115
negative regulation of gene expression GO:0010629 387 0.113
Mouse
positive regulation of protein metabolic process GO:0051247 128 0.110
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.109
morphogenesis of follicular epithelium GO:0016333 36 0.109
adult behavior GO:0030534 137 0.107
regulation of cellular localization GO:0060341 136 0.107
positive regulation of cellular protein metabolic process GO:0032270 118 0.106
positive regulation of rna metabolic process GO:0051254 271 0.106
sex differentiation GO:0007548 81 0.106
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.102
endodermal cell fate commitment GO:0001711 3 0.101
maternal determination of anterior posterior axis embryo GO:0008358 74 0.101
cellular macromolecule catabolic process GO:0044265 136 0.101
meiosis i GO:0007127 59 0.100
Mouse
cellular protein modification process GO:0006464 438 0.100
cytoplasm organization GO:0007028 64 0.099
cell cycle checkpoint GO:0000075 95 0.099
protein modification process GO:0036211 438 0.098
mitotic sister chromatid segregation GO:0000070 87 0.097
transcription from rna polymerase ii promoter GO:0006366 368 0.095
regulation of multicellular organismal development GO:2000026 414 0.095
regulation of nuclear division GO:0051783 58 0.095
regulation of protein kinase activity GO:0045859 51 0.094
post embryonic appendage morphogenesis GO:0035120 385 0.092
mitotic cell cycle checkpoint GO:0007093 88 0.090
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.087
regulation of mrna 3 end processing GO:0031440 7 0.086
regulation of reproductive process GO:2000241 54 0.086
positive regulation of mitotic cell cycle GO:0045931 34 0.085
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.085
regulation of translation GO:0006417 56 0.084
mitotic cell cycle phase transition GO:0044772 138 0.084
regulation of phosphorus metabolic process GO:0051174 210 0.083
stem cell development GO:0048864 79 0.083
gene silencing by rna GO:0031047 57 0.082
egg coat formation GO:0035803 11 0.080
cellular macromolecule localization GO:0070727 220 0.080
tube morphogenesis GO:0035239 191 0.080
positive regulation of rna biosynthetic process GO:1902680 266 0.078
dna conformation change GO:0071103 105 0.077
imaginal disc derived appendage morphogenesis GO:0035114 395 0.076
positive regulation of cell cycle process GO:0090068 28 0.076
posttranscriptional regulation of gene expression GO:0010608 145 0.076
defense response to bacterium GO:0042742 178 0.074
establishment or maintenance of cell polarity GO:0007163 167 0.072
positive regulation of mrna metabolic process GO:1903313 5 0.072
imaginal disc derived wing morphogenesis GO:0007476 337 0.071
rna interference GO:0016246 27 0.070
regulation of phosphorylation GO:0042325 147 0.070
cellular catabolic process GO:0044248 372 0.069
positive regulation of cell cycle GO:0045787 43 0.069
regulation of cellular amino acid metabolic process GO:0006521 0 0.069
germarium derived female germ line cyst formation GO:0030727 42 0.068
regulation of cell division GO:0051302 72 0.067
negative regulation of cellular protein metabolic process GO:0032269 85 0.066
Mouse
central nervous system development GO:0007417 201 0.066
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.066
Mouse
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.066
response to external biotic stimulus GO:0043207 293 0.065
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 4 0.065
specification of axis polarity GO:0065001 6 0.064
nephron epithelium morphogenesis GO:0072088 3 0.063
regulation of proteolysis GO:0030162 87 0.063
negative regulation of translation GO:0017148 28 0.063
Mouse
compound eye retinal cell programmed cell death GO:0046667 23 0.063
negative regulation of mitotic cell cycle GO:0045930 109 0.062
regulation of localization GO:0032879 275 0.062
spermatogenesis GO:0007283 200 0.062
response to bacterium GO:0009617 198 0.062
negative regulation of rna metabolic process GO:0051253 251 0.062
single organism behavior GO:0044708 391 0.062
protein processing GO:0016485 68 0.062
positive regulation of phosphorylation GO:0042327 87 0.062
cell cycle g2 m phase transition GO:0044839 22 0.061
dorsal ventral axis specification GO:0009950 66 0.061
catabolic process GO:0009056 409 0.061
mitotic g2 m transition checkpoint GO:0044818 70 0.058
gonad development GO:0008406 50 0.058
chromosome condensation GO:0030261 41 0.058
vitelline membrane formation involved in chorion containing eggshell formation GO:0007305 11 0.057
eggshell chorion gene amplification GO:0007307 9 0.056
ovarian fusome organization GO:0030723 11 0.056
germ line stem cell maintenance GO:0030718 50 0.056
negative regulation of cell cycle phase transition GO:1901988 103 0.056
cell cell signaling involved in cell fate commitment GO:0045168 210 0.055
negative regulation of protein metabolic process GO:0051248 85 0.054
Mouse
regulation of multi organism process GO:0043900 131 0.054
single organism biosynthetic process GO:0044711 206 0.054
microtubule organizing center organization GO:0031023 168 0.053
kidney development GO:0001822 3 0.053
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.052
sister chromatid segregation GO:0000819 92 0.052
organic substance catabolic process GO:1901575 308 0.052
response to biotic stimulus GO:0009607 294 0.052
eye morphogenesis GO:0048592 260 0.051
phosphorylation GO:0016310 294 0.051
cellular amine metabolic process GO:0044106 12 0.050
regulation of cell proliferation GO:0042127 163 0.049
regulation of meiosis GO:0040020 3 0.048
body morphogenesis GO:0010171 2 0.048
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.048
regulation of cellular component biogenesis GO:0044087 201 0.047
tissue morphogenesis GO:0048729 297 0.047
immune response GO:0006955 246 0.047
imaginal disc derived appendage development GO:0048737 399 0.046
cell motility GO:0048870 251 0.046
brain development GO:0007420 120 0.046
regulation of response to stress GO:0080134 200 0.046
innate immune response GO:0045087 144 0.046
mrna processing GO:0006397 104 0.045
positive regulation of mrna processing GO:0050685 4 0.045
positive regulation of response to stimulus GO:0048584 323 0.045
lateral inhibition GO:0046331 206 0.045
hindbrain development GO:0030902 2 0.044
negative regulation of cell communication GO:0010648 223 0.044
regulation of cellular amine metabolic process GO:0033238 3 0.044
reproductive system development GO:0061458 74 0.043
regulation of gene expression epigenetic GO:0040029 128 0.043
cellular response to organic substance GO:0071310 132 0.043
Mouse
regulation of oskar mrna translation GO:0046011 8 0.043
sister chromatid cohesion GO:0007062 18 0.043
regulation of mitosis GO:0007088 56 0.042
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.042
germ line cyst formation GO:0048134 44 0.042
inter male aggressive behavior GO:0002121 60 0.042
macromolecule catabolic process GO:0009057 161 0.041
defense response GO:0006952 300 0.041
cell division GO:0051301 248 0.041
metal ion transport GO:0030001 74 0.041
mrna polyadenylation GO:0006378 11 0.040
dna alkylation GO:0006305 4 0.040
dna methylation GO:0006306 4 0.040
negative regulation of cell differentiation GO:0045596 143 0.039
protein catabolic process GO:0030163 101 0.038
long term memory GO:0007616 62 0.038
amine metabolic process GO:0009308 12 0.038
response to organic substance GO:0010033 284 0.037
Mouse
cellular ketone metabolic process GO:0042180 24 0.037
small molecule metabolic process GO:0044281 305 0.037
cell cycle dna replication GO:0044786 23 0.037
extracellular structure organization GO:0043062 46 0.037
regulation of cellular catabolic process GO:0031329 157 0.036
polarity specification of anterior posterior axis GO:0009949 5 0.036
regulation of canonical wnt signaling pathway GO:0060828 15 0.035
reciprocal meiotic recombination GO:0007131 19 0.035
camera type eye development GO:0043010 4 0.035
endocytosis GO:0006897 310 0.035
terminal region determination GO:0007362 25 0.034
chorion containing eggshell pattern formation GO:0030381 11 0.034
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.034
mesenchymal cell differentiation GO:0048762 1 0.034
compound eye morphogenesis GO:0001745 249 0.034
stem cell differentiation GO:0048863 117 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.033
appendage morphogenesis GO:0035107 397 0.033
regulation of catalytic activity GO:0050790 185 0.033
endoderm formation GO:0001706 3 0.033
regulation of protein catabolic process GO:0042176 55 0.033
regulation of cellular ketone metabolic process GO:0010565 3 0.032
positive regulation of nucleic acid templated transcription GO:1903508 266 0.032
imaginal disc derived wing vein specification GO:0007474 48 0.032
response to oxygen containing compound GO:1901700 200 0.031
Mouse
mitotic g2 dna damage checkpoint GO:0007095 69 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.030
cation transport GO:0006812 110 0.030
negative regulation of rna biosynthetic process GO:1902679 240 0.030
actin filament based process GO:0030029 220 0.030
regulation of phosphate metabolic process GO:0019220 210 0.029
rna processing GO:0006396 147 0.029
neuroblast fate determination GO:0007400 12 0.029
female germ line cyst formation GO:0048135 42 0.029
regulation of immune response GO:0050776 118 0.029
appendage development GO:0048736 401 0.029
mitotic chromosome condensation GO:0007076 22 0.029
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.029
regulation of lipid transport GO:0032368 3 0.028
regulation of cell development GO:0060284 215 0.028
regulation of organelle organization GO:0033043 196 0.028
positive regulation of stem cell differentiation GO:2000738 3 0.028
reproductive structure development GO:0048608 74 0.027
regulation of protein phosphorylation GO:0001932 64 0.027
meiotic cell cycle process GO:1903046 132 0.027
Mouse
stem cell maintenance GO:0019827 67 0.027
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.027
female germ line stem cell asymmetric division GO:0048132 14 0.027
response to inorganic substance GO:0010035 44 0.026
regulation of catabolic process GO:0009894 170 0.026
meiotic cell cycle GO:0051321 171 0.026
Mouse
regulation of kinase activity GO:0043549 53 0.026
cell migration GO:0016477 238 0.026
nephron development GO:0072006 3 0.026
positive regulation of cellular amine metabolic process GO:0033240 0 0.026
chromosome organization involved in meiosis GO:0070192 10 0.025
Mouse
branching morphogenesis of an epithelial tube GO:0048754 45 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.025
Mouse
peptidyl amino acid modification GO:0018193 105 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
modification dependent protein catabolic process GO:0019941 78 0.025
negative regulation of dna metabolic process GO:0051053 12 0.024
organonitrogen compound metabolic process GO:1901564 318 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.024
regulation of transferase activity GO:0051338 58 0.024
organic acid metabolic process GO:0006082 103 0.024
positive regulation of exocytosis GO:0045921 4 0.024
learning or memory GO:0007611 141 0.024
fertilization GO:0009566 26 0.023
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
kidney morphogenesis GO:0060993 3 0.023
regulation of erbb signaling pathway GO:1901184 42 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
mesenchymal cell development GO:0014031 1 0.023
regulation of defense response GO:0031347 102 0.023
axon guidance GO:0007411 233 0.023
regulation of epithelial cell proliferation GO:0050678 4 0.023
ribonucleoprotein complex subunit organization GO:0071826 28 0.023
neurological system process GO:0050877 358 0.023
organonitrogen compound biosynthetic process GO:1901566 117 0.022
extracellular matrix organization GO:0030198 32 0.022
positive regulation of catabolic process GO:0009896 105 0.022
positive regulation of proteolysis GO:0045862 52 0.022
signal transduction by phosphorylation GO:0023014 107 0.022
enzyme linked receptor protein signaling pathway GO:0007167 179 0.022
protein maturation GO:0051604 71 0.022
aromatic compound catabolic process GO:0019439 166 0.022
border follicle cell migration GO:0007298 113 0.022
phagocytosis GO:0006909 215 0.022
macromolecular complex assembly GO:0065003 256 0.021
nephron tubule morphogenesis GO:0072078 3 0.021
negative regulation of transcription dna templated GO:0045892 237 0.021
morphogenesis of a branching epithelium GO:0061138 45 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.021
cognition GO:0050890 141 0.021
cellular response to dna damage stimulus GO:0006974 223 0.021
dna duplex unwinding GO:0032508 16 0.021
organelle assembly GO:0070925 198 0.021
mitotic recombination GO:0006312 2 0.021
regulation of transposition GO:0010528 13 0.021
establishment of localization in cell GO:0051649 402 0.021
regulation of protein modification process GO:0031399 112 0.020
kidney epithelium development GO:0072073 3 0.020
erbb signaling pathway GO:0038127 58 0.020
positive regulation of mrna 3 end processing GO:0031442 4 0.020
nucleobase containing compound catabolic process GO:0034655 165 0.020
anatomical structure homeostasis GO:0060249 97 0.020
positive regulation of cell communication GO:0010647 250 0.020
negative regulation of signal transduction GO:0009968 206 0.020
lipid metabolic process GO:0006629 121 0.020
sensory organ morphogenesis GO:0090596 260 0.020
regulation of mapk cascade GO:0043408 92 0.019
nephron tubule development GO:0072080 3 0.019
intracellular transport GO:0046907 228 0.019
response to abiotic stimulus GO:0009628 341 0.019
Mouse
positive regulation of signaling GO:0023056 243 0.019
positive regulation of protein phosphorylation GO:0001934 34 0.019
regulation of transport GO:0051049 181 0.019
regulation of mrna metabolic process GO:1903311 72 0.018
pronuclear migration GO:0035046 4 0.018
ameboidal type cell migration GO:0001667 151 0.018
positive regulation of immune system process GO:0002684 68 0.018
morphogenesis of an epithelium GO:0002009 276 0.018
regulation of mrna processing GO:0050684 71 0.018
regulation of nervous system development GO:0051960 248 0.018
protein phosphorylation GO:0006468 169 0.018
learning GO:0007612 75 0.018
apoptotic process GO:0006915 159 0.018
Worm
regulation of cholesterol transport GO:0032374 1 0.018
organic substance transport GO:0071702 257 0.018
double strand break repair GO:0006302 26 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
mrna catabolic process GO:0006402 33 0.018
positive regulation of mapk cascade GO:0043410 63 0.017
regulation of protein serine threonine kinase activity GO:0071900 25 0.017
germ line stem cell division GO:0042078 25 0.017
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
positive regulation of cellular catabolic process GO:0031331 95 0.017
cellularization GO:0007349 90 0.017
ubiquitin dependent protein catabolic process GO:0006511 78 0.017
embryo development ending in birth or egg hatching GO:0009792 152 0.017
Worm
nephron epithelium development GO:0072009 3 0.017
protein localization GO:0008104 284 0.017
regulation of dna recombination GO:0000018 4 0.017
taxis GO:0042330 304 0.017
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.017
negative regulation of response to stimulus GO:0048585 258 0.016
response to lipopolysaccharide GO:0032496 4 0.016
immune effector process GO:0002252 98 0.016
mesoderm development GO:0007498 78 0.016
telomere maintenance via recombination GO:0000722 1 0.016
morphogenesis of embryonic epithelium GO:0016331 94 0.016
ovarian follicle cell migration GO:0007297 121 0.016
oxoacid metabolic process GO:0043436 103 0.016
negative regulation of signaling GO:0023057 219 0.016
protein localization to organelle GO:0033365 82 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
carboxylic acid metabolic process GO:0019752 92 0.015
imaginal disc pattern formation GO:0007447 91 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
cellular protein catabolic process GO:0044257 83 0.015
regulation of nucleocytoplasmic transport GO:0046822 35 0.015
production of sirna involved in rna interference GO:0030422 11 0.015
negative regulation of cell division GO:0051782 17 0.015
tissue migration GO:0090130 155 0.015
development of primary sexual characteristics GO:0045137 50 0.015
death GO:0016265 284 0.015
Worm
negative regulation of cellular component organization GO:0051129 108 0.015
regulation of cell differentiation GO:0045595 302 0.015
chromatin silencing GO:0006342 76 0.015
positive regulation of organelle organization GO:0010638 65 0.015
epithelium migration GO:0090132 148 0.014
regulation of molecular function GO:0065009 217 0.014
cellular protein complex assembly GO:0043623 71 0.014
modification dependent macromolecule catabolic process GO:0043632 79 0.014
single organism intracellular transport GO:1902582 207 0.014
negative regulation of protein processing GO:0010955 31 0.014
macromolecule methylation GO:0043414 45 0.014
secretion by cell GO:0032940 101 0.014
negative regulation of meiotic cell cycle GO:0051447 2 0.014
regulation of mrna catabolic process GO:0061013 5 0.013
production of small rna involved in gene silencing by rna GO:0070918 15 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.013
positive regulation of immune response GO:0050778 63 0.013
rna catabolic process GO:0006401 37 0.013
intracellular signal transduction GO:0035556 300 0.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.013
microtubule polymerization or depolymerization GO:0031109 39 0.013
karyogamy GO:0000741 4 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
mesenchyme development GO:0060485 9 0.013
eye development GO:0001654 323 0.013
head development GO:0060322 135 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
cellular response to organic cyclic compound GO:0071407 32 0.013
pirna metabolic process GO:0034587 10 0.013
pronuclear fusion GO:0007344 4 0.013
chromatin remodeling GO:0006338 72 0.013
muscle structure development GO:0061061 224 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.013
lipid biosynthetic process GO:0008610 46 0.013
response to desiccation GO:0009269 3 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
regulation of cellular protein catabolic process GO:1903362 44 0.013
defense response to other organism GO:0098542 225 0.013
immune response regulating signaling pathway GO:0002764 2 0.012
chemotaxis GO:0006935 249 0.012
positive regulation of cell motility GO:2000147 3 0.012
axon development GO:0061564 297 0.012
cellular response to dsrna GO:0071359 15 0.012
regulation of protein tyrosine kinase activity GO:0061097 9 0.012
homeostatic process GO:0042592 199 0.012
tor signaling GO:0031929 32 0.012
regulation of innate immune response GO:0045088 71 0.012
male meiosis i GO:0007141 9 0.012
female meiotic division GO:0007143 70 0.012
lipid localization GO:0010876 54 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
parallel actin filament bundle assembly GO:0030046 2 0.012
actin cytoskeleton organization GO:0030036 206 0.012
digestive tract morphogenesis GO:0048546 127 0.012
dna recombination GO:0006310 32 0.012
positive regulation of cell migration GO:0030335 2 0.012
genital disc development GO:0035215 44 0.012
salivary gland morphogenesis GO:0007435 145 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
response to alcohol GO:0097305 95 0.012
negative regulation of dna recombination GO:0045910 2 0.012
transmembrane transport GO:0055085 139 0.012
dna integrity checkpoint GO:0031570 81 0.012
positive regulation of protein catabolic process GO:0045732 34 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012

orb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.108
cancer DOID:162 0 0.101
disease of cellular proliferation DOID:14566 0 0.101
organ system cancer DOID:0050686 0 0.055
thoracic cancer DOID:5093 0 0.049
hypertension DOID:10763 0 0.031
artery disease DOID:0050828 0 0.031
vascular disease DOID:178 0 0.031
essential hypertension DOID:10825 0 0.031
cardiovascular system disease DOID:1287 0 0.031
musculoskeletal system disease DOID:17 0 0.030
breast cancer DOID:1612 0 0.023
immune system disease DOID:2914 0 0.018
anemia DOID:2355 0 0.018
hematopoietic system disease DOID:74 0 0.018
aplastic anemia DOID:12449 0 0.017
bone marrow disease DOID:4961 0 0.017