Drosophila melanogaster

60 known processes

Atg12 (Dmel_CG10861)

Autophagy-specific gene 12

(Aliases: atg12,CG10861,Dmel\CG10861)

Atg12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle structure development GO:0061061 224 0.199
programmed cell death GO:0012501 257 0.175
death GO:0016265 284 0.164
regulation of anatomical structure morphogenesis GO:0022603 242 0.145
positive regulation of response to stimulus GO:0048584 323 0.126
positive regulation of signal transduction GO:0009967 223 0.123
cell death GO:0008219 279 0.117
positive regulation of cell communication GO:0010647 250 0.107
regulation of tor signaling GO:0032006 21 0.105
positive regulation of signaling GO:0023056 243 0.090
actin filament based process GO:0030029 220 0.090
regulation of cell cycle GO:0051726 291 0.085
developmental programmed cell death GO:0010623 138 0.084
regulation of cell death GO:0010941 173 0.080
gland development GO:0048732 191 0.078
phosphorylation GO:0016310 294 0.077
regulation of intracellular signal transduction GO:1902531 236 0.075
intracellular signal transduction GO:0035556 300 0.074
negative regulation of cellular metabolic process GO:0031324 382 0.072
positive regulation of rna metabolic process GO:0051254 271 0.068
tor signaling GO:0031929 32 0.064
positive regulation of rna biosynthetic process GO:1902680 266 0.063
cell motility GO:0048870 251 0.058
cellular response to chemical stimulus GO:0070887 199 0.055
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.055
localization of cell GO:0051674 257 0.053
autophagy GO:0006914 108 0.053
larval midgut histolysis GO:0035069 22 0.051
response to external biotic stimulus GO:0043207 293 0.051
regulation of programmed cell death GO:0043067 152 0.046
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.045
histolysis GO:0007559 102 0.044
single organism behavior GO:0044708 391 0.044
carboxylic acid metabolic process GO:0019752 92 0.043
cellular protein modification process GO:0006464 438 0.043
Yeast
regulation of cell morphogenesis GO:0022604 163 0.041
small molecule metabolic process GO:0044281 305 0.041
regulation of immune system process GO:0002682 176 0.040
positive regulation of biosynthetic process GO:0009891 316 0.040
regulation of mapk cascade GO:0043408 92 0.039
exocrine system development GO:0035272 162 0.037
regulation of cell shape GO:0008360 113 0.036
positive regulation of cellular biosynthetic process GO:0031328 316 0.036
regulation of multicellular organismal development GO:2000026 414 0.035
organonitrogen compound metabolic process GO:1901564 318 0.034
cell migration GO:0016477 238 0.034
positive regulation of macromolecule metabolic process GO:0010604 405 0.034
actin filament organization GO:0007015 126 0.033
defense response to other organism GO:0098542 225 0.031
apoptotic process GO:0006915 159 0.031
cellular amine metabolic process GO:0044106 12 0.031
cytoplasmic transport GO:0016482 130 0.031
Yeast
eye development GO:0001654 323 0.031
negative regulation of developmental process GO:0051093 201 0.031
forebrain development GO:0030900 2 0.029
regulation of localization GO:0032879 275 0.029
cell fate determination GO:0001709 91 0.029
enzyme linked receptor protein signaling pathway GO:0007167 179 0.029
regionalization GO:0003002 416 0.028
regulation of cellular amine metabolic process GO:0033238 3 0.028
positive regulation of intracellular signal transduction GO:1902533 116 0.028
actin cytoskeleton organization GO:0030036 206 0.028
response to nutrient levels GO:0031667 114 0.027
positive regulation of nucleic acid templated transcription GO:1903508 266 0.027
regulation of cell differentiation GO:0045595 302 0.027
peptidyl amino acid modification GO:0018193 105 0.027
transcription from rna polymerase ii promoter GO:0006366 368 0.026
epithelial cell differentiation GO:0030855 322 0.026
positive regulation of phosphorus metabolic process GO:0010562 139 0.025
positive regulation of tor signaling GO:0032008 13 0.025
mapk cascade GO:0000165 107 0.024
regulation of phosphate metabolic process GO:0019220 210 0.023
organic acid metabolic process GO:0006082 103 0.023
gland morphogenesis GO:0022612 145 0.023
phagocytosis GO:0006909 215 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.022
single organism biosynthetic process GO:0044711 206 0.022
positive regulation of transcription dna templated GO:0045893 266 0.022
regulation of organelle organization GO:0033043 196 0.022
cellular catabolic process GO:0044248 372 0.022
regulation of neurogenesis GO:0050767 158 0.022
response to other organism GO:0051707 293 0.022
salivary gland morphogenesis GO:0007435 145 0.022
intracellular transport GO:0046907 228 0.022
Yeast
regulation of phosphorus metabolic process GO:0051174 210 0.022
response to biotic stimulus GO:0009607 294 0.021
tissue morphogenesis GO:0048729 297 0.021
organic substance transport GO:0071702 257 0.021
Yeast
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
cell adhesion GO:0007155 136 0.021
central nervous system development GO:0007417 201 0.021
regulation of apoptotic process GO:0042981 130 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
neurological system process GO:0050877 358 0.021
positive regulation of gene expression GO:0010628 290 0.020
regulation of nervous system development GO:0051960 248 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.020
adult behavior GO:0030534 137 0.020
regulation of cell proliferation GO:0042127 163 0.020
regulation of secretion GO:0051046 44 0.020
immune effector process GO:0002252 98 0.020
regulation of response to stress GO:0080134 200 0.020
growth GO:0040007 359 0.020
meiotic cell cycle GO:0051321 171 0.019
muscle cell differentiation GO:0042692 103 0.019
macroautophagy GO:0016236 42 0.019
single organism intracellular transport GO:1902582 207 0.019
Yeast
positive regulation of programmed cell death GO:0043068 62 0.019
head development GO:0060322 135 0.019
oxoacid metabolic process GO:0043436 103 0.019
autophagic cell death GO:0048102 83 0.019
protein localization GO:0008104 284 0.019
Yeast
salivary gland histolysis GO:0035070 88 0.018
positive regulation of developmental process GO:0051094 143 0.018
imaginal disc derived appendage development GO:0048737 399 0.018
protein modification process GO:0036211 438 0.018
Yeast
vesicle mediated transport GO:0016192 381 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
amine metabolic process GO:0009308 12 0.018
regulation of cell development GO:0060284 215 0.018
regulation of transport GO:0051049 181 0.018
dendrite development GO:0016358 204 0.017
regulation of sequestering of calcium ion GO:0051282 3 0.017
response to oxygen containing compound GO:1901700 200 0.017
ameboidal type cell migration GO:0001667 151 0.017
negative regulation of cell differentiation GO:0045596 143 0.017
larval midgut cell programmed cell death GO:0035096 19 0.017
endocytosis GO:0006897 310 0.017
synapse assembly GO:0007416 143 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
stem cell maintenance GO:0019827 67 0.016
wnt signaling pathway GO:0016055 98 0.016
chromosome organization GO:0051276 360 0.016
internal peptidyl lysine acetylation GO:0018393 38 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
catabolic process GO:0009056 409 0.016
cellular response to organic substance GO:0071310 132 0.016
brain development GO:0007420 120 0.016
dendrite morphogenesis GO:0048813 199 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
compound eye morphogenesis GO:0001745 249 0.016
regulation of growth GO:0040008 233 0.015
cellular response to endogenous stimulus GO:0071495 80 0.015
signal transduction by phosphorylation GO:0023014 107 0.015
imaginal disc derived appendage morphogenesis GO:0035114 395 0.015
positive regulation of phosphorylation GO:0042327 87 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
single organismal cell cell adhesion GO:0016337 45 0.015
negative regulation of nervous system development GO:0051961 92 0.015
peptidyl lysine modification GO:0018205 57 0.015
epithelial cell migration GO:0010631 148 0.015
memory GO:0007613 94 0.015
nitrogen compound transport GO:0071705 85 0.014
regulation of phosphorylation GO:0042325 147 0.014
covalent chromatin modification GO:0016569 106 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
regulation of cellular response to stress GO:0080135 89 0.014
chromatin organization GO:0006325 207 0.014
purine containing compound metabolic process GO:0072521 155 0.014
positive regulation of cell death GO:0010942 69 0.014
regulation of protein metabolic process GO:0051246 256 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
negative regulation of apoptotic process GO:0043066 63 0.014
immune response GO:0006955 246 0.014
regulation of defense response GO:0031347 102 0.013
cellular response to nutrient levels GO:0031669 62 0.013
defense response to bacterium GO:0042742 178 0.013
determination of adult lifespan GO:0008340 137 0.013
embryonic morphogenesis GO:0048598 206 0.013
response to bacterium GO:0009617 198 0.013
response to organic substance GO:0010033 284 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
locomotory behavior GO:0007626 176 0.013
negative regulation of sequestering of calcium ion GO:0051283 2 0.013
tissue death GO:0016271 102 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
oxidation reduction process GO:0055114 123 0.013
rna processing GO:0006396 147 0.013
biological adhesion GO:0022610 138 0.013
histone acetylation GO:0016573 38 0.013
regulation of cell projection organization GO:0031344 92 0.013
developmental growth GO:0048589 280 0.013
cation transport GO:0006812 110 0.012
cardiovascular system development GO:0072358 82 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
regulation of immune response GO:0050776 118 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
peptidyl lysine acetylation GO:0018394 39 0.012
salivary gland development GO:0007431 162 0.012
cell proliferation GO:0008283 299 0.012
regulation of protein modification process GO:0031399 112 0.012
regulation of stress activated mapk cascade GO:0032872 41 0.012
metal ion homeostasis GO:0055065 44 0.012
regulation of catalytic activity GO:0050790 185 0.012
Yeast
small gtpase mediated signal transduction GO:0007264 88 0.012
regulation of cell cycle process GO:0010564 181 0.012
regulation of molecular function GO:0065009 217 0.012
Yeast
striated muscle cell differentiation GO:0051146 90 0.012
autophagic vacuole assembly GO:0000045 2 0.012
Yeast
regulation of epithelial cell differentiation GO:0030856 4 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
regulation of autophagy GO:0010506 62 0.012
spindle organization GO:0007051 253 0.011
protein phosphorylation GO:0006468 169 0.011
respiratory system development GO:0060541 213 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
detection of stimulus GO:0051606 156 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
eye morphogenesis GO:0048592 260 0.011
hindbrain development GO:0030902 2 0.011
negative regulation of gene expression GO:0010629 387 0.011
spermatogenesis GO:0007283 200 0.011
response to abiotic stimulus GO:0009628 341 0.011
protein modification by small protein conjugation GO:0032446 79 0.011
camera type eye development GO:0043010 4 0.011
cellular response to nitrogen compound GO:1901699 51 0.011
regulation of hydrolase activity GO:0051336 97 0.011
defense response GO:0006952 300 0.011
secretion by cell GO:0032940 101 0.011
compound eye development GO:0048749 307 0.011
immune system process GO:0002376 347 0.011
establishment of localization in cell GO:0051649 402 0.011
Yeast
ribonucleotide metabolic process GO:0009259 145 0.011
jnk cascade GO:0007254 50 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
vesicle organization GO:0016050 44 0.010
nucleocytoplasmic transport GO:0006913 72 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
response to wounding GO:0009611 94 0.010
chromatin modification GO:0016568 147 0.010
maintenance of location GO:0051235 73 0.010
developmental maturation GO:0021700 172 0.010
multicellular organismal aging GO:0010259 140 0.010
negative regulation of programmed cell death GO:0043069 72 0.010
negative regulation of cellular component organization GO:0051129 108 0.010
protein acylation GO:0043543 42 0.010

Atg12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016