Drosophila melanogaster

44 known processes

GluClalpha (Dmel_CG7535)

CG7535 gene product from transcript CG7535-RG

(Aliases: DrosGluCl,GluCl,BcDNA:HL07853,DrosGluCl-alpha,DmGluClalpha,dGluCl-alpha,glc,CG7535,GLUCL,DmGlu,GluCla,Dmel\CG7535,DrosGluCl-alpha1,Dm-GluCl,DrosGlu-Cl-alpha)

GluClalpha biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of response to stimulus GO:0048584 323 0.144
positive regulation of signaling GO:0023056 243 0.100
neurological system process GO:0050877 358 0.093
Fly
small molecule metabolic process GO:0044281 305 0.089
positive regulation of cell communication GO:0010647 250 0.078
regulation of multicellular organismal development GO:2000026 414 0.076
acetate ester metabolic process GO:1900619 2 0.074
learning or memory GO:0007611 141 0.073
Fly
response to oxygen containing compound GO:1901700 200 0.072
negative regulation of cellular metabolic process GO:0031324 382 0.070
positive regulation of signal transduction GO:0009967 223 0.069
eye development GO:0001654 323 0.069
acetylcholine metabolic process GO:0008291 2 0.063
response to organic substance GO:0010033 284 0.063
intracellular signal transduction GO:0035556 300 0.063
sensory organ morphogenesis GO:0090596 260 0.061
regulation of cell development GO:0060284 215 0.056
cation transport GO:0006812 110 0.055
single organism biosynthetic process GO:0044711 206 0.054
ras protein signal transduction GO:0007265 88 0.054
neurotransmitter metabolic process GO:0042133 2 0.054
response to alcohol GO:0097305 95 0.053
regulation of phosphate metabolic process GO:0019220 210 0.053
regulation of intracellular signal transduction GO:1902531 236 0.051
single organism behavior GO:0044708 391 0.050
Fly
regulation of cell projection organization GO:0031344 92 0.050
response to abiotic stimulus GO:0009628 341 0.049
Fly
cell proliferation GO:0008283 299 0.047
positive regulation of intracellular signal transduction GO:1902533 116 0.047
ion transport GO:0006811 145 0.046
negative regulation of signal transduction GO:0009968 206 0.046
negative regulation of response to stimulus GO:0048585 258 0.045
regulation of cell differentiation GO:0045595 302 0.044
cognition GO:0050890 141 0.044
Fly
g protein coupled receptor signaling pathway GO:0007186 136 0.044
transcription from rna polymerase ii promoter GO:0006366 368 0.043
regulation of small gtpase mediated signal transduction GO:0051056 93 0.042
negative regulation of signaling GO:0023057 219 0.041
Fly
organonitrogen compound metabolic process GO:1901564 318 0.041
phosphorylation GO:0016310 294 0.041
small gtpase mediated signal transduction GO:0007264 88 0.040
regulation of neuron projection development GO:0010975 69 0.040
regulation of neurogenesis GO:0050767 158 0.040
head development GO:0060322 135 0.040
positive regulation of cell projection organization GO:0031346 29 0.039
taxis GO:0042330 304 0.039
regulation of nervous system development GO:0051960 248 0.037
regulation of phosphorylation GO:0042325 147 0.037
signal transduction by phosphorylation GO:0023014 107 0.037
regulation of neuron differentiation GO:0045664 103 0.036
transmembrane transport GO:0055085 139 0.036
carboxylic acid metabolic process GO:0019752 92 0.036
response to lipopolysaccharide GO:0032496 4 0.036
regulation of mapk cascade GO:0043408 92 0.035
negative regulation of cell communication GO:0010648 223 0.034
Fly
mapk cascade GO:0000165 107 0.033
metal ion transport GO:0030001 74 0.033
regulation of ras protein signal transduction GO:0046578 93 0.033
organophosphate metabolic process GO:0019637 195 0.033
neuron recognition GO:0008038 101 0.032
positive regulation of macromolecule metabolic process GO:0010604 405 0.032
organic acid metabolic process GO:0006082 103 0.032
axonogenesis GO:0007409 290 0.031
biological adhesion GO:0022610 138 0.030
sensory perception of salty taste GO:0050914 3 0.030
synaptic transmission GO:0007268 288 0.030
Fly
sensory perception of chemical stimulus GO:0007606 116 0.029
positive regulation of cellular component organization GO:0051130 156 0.028
positive regulation of developmental process GO:0051094 143 0.028
adult behavior GO:0030534 137 0.028
compound eye development GO:0048749 307 0.028
regulation of cell proliferation GO:0042127 163 0.028
negative regulation of rna biosynthetic process GO:1902679 240 0.028
locomotory behavior GO:0007626 176 0.028
Worm
regulation of catalytic activity GO:0050790 185 0.028
eye morphogenesis GO:0048592 260 0.027
appendage development GO:0048736 401 0.027
carbohydrate derivative metabolic process GO:1901135 217 0.027
divalent metal ion transport GO:0070838 26 0.027
regulation of cell cycle GO:0051726 291 0.027
positive regulation of nervous system development GO:0051962 69 0.027
associative learning GO:0008306 65 0.026
Fly
brain development GO:0007420 120 0.026
organic substance transport GO:0071702 257 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.026
positive regulation of cellular biosynthetic process GO:0031328 316 0.026
negative regulation of biosynthetic process GO:0009890 277 0.026
negative regulation of nucleic acid templated transcription GO:1903507 240 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
chemotaxis GO:0006935 249 0.025
cell cell adhesion GO:0098609 26 0.025
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.025
positive regulation of multicellular organismal process GO:0051240 143 0.025
appendage morphogenesis GO:0035107 397 0.025
nucleobase containing small molecule metabolic process GO:0055086 174 0.025
camera type eye development GO:0043010 4 0.025
positive regulation of gene expression GO:0010628 290 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
oxoacid metabolic process GO:0043436 103 0.025
immune system process GO:0002376 347 0.025
nucleotide metabolic process GO:0009117 161 0.025
regulation of transport GO:0051049 181 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
regulation of localization GO:0032879 275 0.024
ribose phosphate metabolic process GO:0019693 145 0.024
purine containing compound metabolic process GO:0072521 155 0.024
establishment of localization in cell GO:0051649 402 0.024
purine ribonucleotide metabolic process GO:0009150 145 0.023
neuron projection guidance GO:0097485 241 0.023
forebrain development GO:0030900 2 0.023
regionalization GO:0003002 416 0.023
response to ethanol GO:0045471 59 0.022
growth GO:0040007 359 0.022
negative regulation of rna metabolic process GO:0051253 251 0.022
cell adhesion GO:0007155 136 0.022
regulation of molecular function GO:0065009 217 0.022
positive regulation of cell differentiation GO:0045597 64 0.022
mating GO:0007618 120 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.022
negative regulation of cellular biosynthetic process GO:0031327 277 0.022
positive regulation of neuron differentiation GO:0045666 26 0.022
salt aversion GO:0035199 3 0.022
phagocytosis GO:0006909 215 0.021
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.021
cell cycle phase transition GO:0044770 140 0.021
segmentation GO:0035282 207 0.021
endocytosis GO:0006897 310 0.021
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.021
store operated calcium entry GO:0002115 3 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.021
positive regulation of ras protein signal transduction GO:0046579 43 0.021
cell cell signaling involved in cell fate commitment GO:0045168 210 0.020
embryonic development via the syncytial blastoderm GO:0001700 148 0.020
positive regulation of neurogenesis GO:0050769 41 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
protein modification process GO:0036211 438 0.020
nucleobase containing compound catabolic process GO:0034655 165 0.020
memory GO:0007613 94 0.020
organic substance catabolic process GO:1901575 308 0.020
response to hypoxia GO:0001666 53 0.020
cellular catabolic process GO:0044248 372 0.020
catabolic process GO:0009056 409 0.020
intracellular transport GO:0046907 228 0.019
response to radiation GO:0009314 155 0.019
body morphogenesis GO:0010171 2 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
ion transmembrane transport GO:0034220 122 0.019
mitotic cell cycle phase transition GO:0044772 138 0.019
cellular ketone metabolic process GO:0042180 24 0.019
positive regulation of molecular function GO:0044093 136 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
cell recognition GO:0008037 102 0.019
cellular protein modification process GO:0006464 438 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.018
enzyme linked receptor protein signaling pathway GO:0007167 179 0.018
sensory perception GO:0007600 196 0.018
cyclic purine nucleotide metabolic process GO:0052652 25 0.018
ribonucleotide metabolic process GO:0009259 145 0.018
axon guidance GO:0007411 233 0.018
response to other organism GO:0051707 293 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
wing disc morphogenesis GO:0007472 344 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
negative regulation of transcription dna templated GO:0045892 237 0.017
post embryonic appendage morphogenesis GO:0035120 385 0.017
axon development GO:0061564 297 0.017
regulation of mitotic cell cycle GO:0007346 190 0.017
synaptic target recognition GO:0008039 45 0.017
developmental maturation GO:0021700 172 0.017
salivary gland morphogenesis GO:0007435 145 0.017
epithelial cell differentiation GO:0030855 322 0.017
photoreceptor cell differentiation GO:0046530 170 0.017
purine nucleoside triphosphate metabolic process GO:0009144 119 0.017
learning GO:0007612 75 0.017
Fly
developmental programmed cell death GO:0010623 138 0.016
kidney development GO:0001822 3 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
erk1 and erk2 cascade GO:0070371 39 0.016
cation transmembrane transport GO:0098655 88 0.016
detection of external stimulus GO:0009581 66 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
cyclic nucleotide metabolic process GO:0009187 28 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
response to glucose GO:0009749 2 0.016
adult locomotory behavior GO:0008344 76 0.016
photoreceptor cell development GO:0042461 96 0.016
single organism catabolic process GO:0044712 228 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
death GO:0016265 284 0.016
connective tissue development GO:0061448 3 0.016
neuromuscular synaptic transmission GO:0007274 67 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
detection of light stimulus GO:0009583 58 0.016
homeostatic process GO:0042592 199 0.015
multi organism behavior GO:0051705 175 0.015
Fly
response to external biotic stimulus GO:0043207 293 0.015
imaginal disc derived appendage development GO:0048737 399 0.015
regulation of cell cycle phase transition GO:1901987 130 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.015
proteolysis GO:0006508 192 0.015
amine metabolic process GO:0009308 12 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
positive regulation of cell motility GO:2000147 3 0.015
mitotic nuclear division GO:0007067 213 0.015
rna localization GO:0006403 115 0.015
salivary gland development GO:0007431 162 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
divalent inorganic cation transport GO:0072511 30 0.015
tube development GO:0035295 244 0.015
cellular response to organic substance GO:0071310 132 0.015
heterocycle catabolic process GO:0046700 166 0.015
aromatic compound catabolic process GO:0019439 166 0.015
regulation of anatomical structure size GO:0090066 163 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
regulation of erk1 and erk2 cascade GO:0070372 39 0.015
nuclear division GO:0000280 332 0.014
response to sterol GO:0036314 34 0.014
regulation of immune system process GO:0002682 176 0.014
organelle fission GO:0048285 340 0.014
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.014
regulation of protein metabolic process GO:0051246 256 0.014
epithelial cell development GO:0002064 274 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
tube morphogenesis GO:0035239 191 0.014
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.014
cellular amine metabolic process GO:0044106 12 0.014
retina development in camera type eye GO:0060041 4 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
single organism intracellular transport GO:1902582 207 0.014
negative regulation of developmental process GO:0051093 201 0.014
eye photoreceptor cell development GO:0042462 81 0.014
cell death GO:0008219 279 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
ribonucleotide biosynthetic process GO:0009260 28 0.014
regulation of cell death GO:0010941 173 0.014
positive regulation of cell migration GO:0030335 2 0.014
compound eye morphogenesis GO:0001745 249 0.014
camera type eye morphogenesis GO:0048593 2 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
defense response to other organism GO:0098542 225 0.014
cyclic nucleotide biosynthetic process GO:0009190 25 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
response to oxygen levels GO:0070482 59 0.014
localization of cell GO:0051674 257 0.013
axis specification GO:0009798 167 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
cell maturation GO:0048469 144 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
developmental growth GO:0048589 280 0.013
regulation of nucleotide metabolic process GO:0006140 62 0.013
response to nutrient levels GO:0031667 114 0.013
lateral inhibition GO:0046331 206 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
tissue death GO:0016271 102 0.013
regulation of cell cycle process GO:0010564 181 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
circadian behavior GO:0048512 76 0.013
Fly
cellular macromolecule catabolic process GO:0044265 136 0.013
sterol homeostasis GO:0055092 4 0.013
cellular response to carbohydrate stimulus GO:0071322 4 0.013
programmed cell death GO:0012501 257 0.013
response to bacterium GO:0009617 198 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
polyol biosynthetic process GO:0046173 3 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
epidermal growth factor receptor signaling pathway GO:0007173 58 0.013
immune response activating signal transduction GO:0002757 2 0.013
vesicle mediated transport GO:0016192 381 0.013
Fly
erbb signaling pathway GO:0038127 58 0.013
nitrogen compound transport GO:0071705 85 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
positive regulation of nucleotide metabolic process GO:0045981 55 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
regulation of response to stress GO:0080134 200 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
cellular macromolecule localization GO:0070727 220 0.013
response to light stimulus GO:0009416 124 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.012
response to organic cyclic compound GO:0014070 89 0.012
actin filament based process GO:0030029 220 0.012
response to decreased oxygen levels GO:0036293 58 0.012
response to hexose GO:0009746 3 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.012
regulation of programmed cell death GO:0043067 152 0.012
neuromuscular junction development GO:0007528 149 0.012
cell growth GO:0016049 108 0.012
calcium ion transport GO:0006816 24 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
positive regulation of lyase activity GO:0051349 10 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
compound eye photoreceptor development GO:0042051 78 0.012
defense response GO:0006952 300 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
embryonic pattern specification GO:0009880 174 0.012
tissue morphogenesis GO:0048729 297 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
regulation of defense response GO:0031347 102 0.012
cell motility GO:0048870 251 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
protein transport GO:0015031 155 0.012
response to organophosphorus GO:0046683 2 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
response to ketone GO:1901654 34 0.012
notch signaling pathway GO:0007219 120 0.012
negative regulation of gene expression GO:0010629 387 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
reproductive behavior GO:0019098 122 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
positive regulation of mapk cascade GO:0043410 63 0.012
gland morphogenesis GO:0022612 145 0.012
steroid catabolic process GO:0006706 1 0.012
mesenchymal cell differentiation GO:0048762 1 0.011
response to endogenous stimulus GO:0009719 119 0.011
nucleoside catabolic process GO:0009164 112 0.011
mesenchymal cell development GO:0014031 1 0.011
imaginal disc pattern formation GO:0007447 91 0.011
response to biotic stimulus GO:0009607 294 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
cytoplasmic transport GO:0016482 130 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
telencephalon development GO:0021537 2 0.011
nucleoside metabolic process GO:0009116 127 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
spermatogenesis GO:0007283 200 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
cation homeostasis GO:0055080 51 0.011
cellular cation homeostasis GO:0030003 38 0.011
regulation of catabolic process GO:0009894 170 0.011
embryonic morphogenesis GO:0048598 206 0.011
macromolecular complex assembly GO:0065003 256 0.011
Worm
regulation of synaptic transmission GO:0050804 69 0.011
Fly
establishment of protein localization GO:0045184 163 0.011
response to monosaccharide GO:0034284 4 0.011
cell migration GO:0016477 238 0.011
response to extracellular stimulus GO:0009991 116 0.011
autophagic cell death GO:0048102 83 0.011
regulation of neurotransmitter levels GO:0001505 38 0.011
vitamin biosynthetic process GO:0009110 1 0.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
regulation of hydrolase activity GO:0051336 97 0.011
stem cell differentiation GO:0048863 117 0.011
cellular protein localization GO:0034613 160 0.011
regulation of transmembrane transport GO:0034762 27 0.011
leg disc development GO:0035218 92 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
cell division GO:0051301 248 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 7 0.011
organophosphate catabolic process GO:0046434 112 0.010
tripartite regional subdivision GO:0007351 103 0.010
salivary gland histolysis GO:0035070 88 0.010
anterior posterior pattern specification GO:0009952 136 0.010
response to ecdysone GO:0035075 34 0.010
metal ion homeostasis GO:0055065 44 0.010
purine containing compound biosynthetic process GO:0072522 30 0.010
regulation of ion transport GO:0043269 39 0.010
protein complex assembly GO:0006461 200 0.010
Worm
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
translation GO:0006412 69 0.010
regulation of purine nucleotide metabolic process GO:1900542 62 0.010
digestive system development GO:0055123 149 0.010
protein heterooligomerization GO:0051291 4 0.010
oocyte construction GO:0007308 112 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
androgen metabolic process GO:0008209 1 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
positive regulation of transcription dna templated GO:0045893 266 0.010
gtp catabolic process GO:0006184 72 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
nucleoside triphosphate catabolic process GO:0009143 108 0.010
chromosome organization GO:0051276 360 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
anatomical structure homeostasis GO:0060249 97 0.010
limb development GO:0060173 1 0.010
positive regulation of cyclase activity GO:0031281 9 0.010

GluClalpha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.022
cardiovascular system disease DOID:1287 0 0.018
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.015
musculoskeletal system disease DOID:17 0 0.013
carbohydrate metabolism disease DOID:0050013 0 0.013
acquired metabolic disease DOID:0060158 0 0.013
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.010
artery disease DOID:0050828 0 0.010
vascular disease DOID:178 0 0.010