Drosophila melanogaster

47 known processes

Mcm2 (Dmel_CG7538)

Minichromosome maintenance 2

(Aliases: CG7538,DmMCM2,MCM2-7,PCR3,dMCM2,DmeMCM2,MCM2,DmMcm2,l(3)rL074,MCM2_DROME,Dmel\CG7538,McM2)

Mcm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna geometric change GO:0032392 16 1.000
dna duplex unwinding GO:0032508 16 0.996
double strand break repair GO:0006302 26 0.984
Yeast
nuclear dna replication GO:0033260 1 0.983
Yeast
cell cycle dna replication GO:0044786 23 0.974
Yeast
dna dependent dna replication GO:0006261 17 0.972
Yeast
dna repair GO:0006281 54 0.929
Yeast
dna conformation change GO:0071103 105 0.863
dna metabolic process GO:0006259 227 0.760
recombinational repair GO:0000725 13 0.666
Yeast
dna endoreduplication GO:0042023 22 0.639
dna replication GO:0006260 48 0.631
Yeast
dna replication initiation GO:0006270 6 0.531
lateral inhibition GO:0046331 206 0.458
double strand break repair via homologous recombination GO:0000724 13 0.420
Yeast
dna packaging GO:0006323 91 0.390
gene silencing GO:0016458 138 0.382
cellular response to dna damage stimulus GO:0006974 223 0.340
Yeast
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.303
cell cell signaling involved in cell fate commitment GO:0045168 210 0.288
dna recombination GO:0006310 32 0.218
Yeast
single organism biosynthetic process GO:0044711 206 0.216
Yeast
dna amplification GO:0006277 11 0.199
organelle assembly GO:0070925 198 0.191
protein dna complex subunit organization GO:0071824 86 0.187
Yeast
regulation of gene expression epigenetic GO:0040029 128 0.173
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.157
macromolecular complex assembly GO:0065003 256 0.145
Yeast
camera type eye morphogenesis GO:0048593 2 0.143
negative regulation of gene expression epigenetic GO:0045814 77 0.137
response to inorganic substance GO:0010035 44 0.136
chromatin silencing GO:0006342 76 0.131
negative regulation of cellular metabolic process GO:0031324 382 0.128
Yeast
embryo development ending in birth or egg hatching GO:0009792 152 0.127
Worm
regulation of mitotic cell cycle phase transition GO:1901990 130 0.117
regulation of cell cycle phase transition GO:1901987 130 0.110
regulation of cell cycle g1 s phase transition GO:1902806 23 0.105
negative regulation of cell cycle process GO:0010948 109 0.104
regulation of transcription by chromatin organization GO:0034401 3 0.098
cellular protein complex assembly GO:0043623 71 0.091
regulation of mitotic cell cycle GO:0007346 190 0.091
mitotic cell cycle phase transition GO:0044772 138 0.089
chromosome separation GO:0051304 42 0.087
cytoplasmic microtubule organization GO:0031122 22 0.087
purine containing compound metabolic process GO:0072521 155 0.086
Yeast
regulation of localization GO:0032879 275 0.083
chromosome segregation GO:0007059 157 0.083
regulation of cell cycle GO:0051726 291 0.083
protein transport GO:0015031 155 0.080
negative regulation of transcription dna templated GO:0045892 237 0.079
mitotic nuclear division GO:0007067 213 0.078
meiotic chromosome segregation GO:0045132 59 0.077
regulation of dna metabolic process GO:0051052 34 0.077
Yeast
metaphase anaphase transition of cell cycle GO:0044784 28 0.077
purine ribonucleoside metabolic process GO:0046128 127 0.076
Yeast
spindle organization GO:0007051 253 0.074
death GO:0016265 284 0.074
sister chromatid segregation GO:0000819 92 0.071
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.070
regulation of multicellular organismal development GO:2000026 414 0.070
glycosyl compound catabolic process GO:1901658 112 0.070
Yeast
purine nucleoside catabolic process GO:0006152 112 0.069
Yeast
nucleobase containing small molecule metabolic process GO:0055086 174 0.067
Yeast
small molecule metabolic process GO:0044281 305 0.067
Yeast
single organism cellular localization GO:1902580 180 0.066
cellular macromolecule localization GO:0070727 220 0.065
protein complex assembly GO:0006461 200 0.064
regulation of gene silencing GO:0060968 63 0.060
cellular macromolecular complex assembly GO:0034622 153 0.059
Yeast
cell cycle checkpoint GO:0000075 95 0.059
regulation of catalytic activity GO:0050790 185 0.059
Yeast
centrosome organization GO:0051297 163 0.058
negative regulation of mitotic cell cycle GO:0045930 109 0.056
cellular protein localization GO:0034613 160 0.056
spindle assembly involved in mitosis GO:0090307 50 0.054
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.053
negative regulation of biosynthetic process GO:0009890 277 0.053
regulation of cellular component biogenesis GO:0044087 201 0.052
dendrite development GO:0016358 204 0.051
cell cycle phase transition GO:0044770 140 0.051
organic substance catabolic process GO:1901575 308 0.049
Yeast
intracellular transport GO:0046907 228 0.047
organophosphate metabolic process GO:0019637 195 0.047
Yeast
camera type eye development GO:0043010 4 0.046
mitotic cell cycle checkpoint GO:0007093 88 0.046
regulation of molecular function GO:0065009 217 0.046
Yeast
chromosome organization GO:0051276 360 0.045
organophosphate catabolic process GO:0046434 112 0.044
Yeast
muscle organ development GO:0007517 127 0.044
growth GO:0040007 359 0.044
nucleoside triphosphate catabolic process GO:0009143 108 0.043
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.043
Yeast
regulation of proteasomal protein catabolic process GO:0061136 39 0.042
immune response GO:0006955 246 0.042
positive regulation of cell cycle phase transition GO:1901989 20 0.042
positive regulation of cell cycle GO:0045787 43 0.042
positive regulation of mitotic cell cycle GO:0045931 34 0.042
reproductive structure development GO:0048608 74 0.040
Worm
purine nucleotide catabolic process GO:0006195 109 0.040
Yeast
endomitotic cell cycle GO:0007113 7 0.040
proteolysis GO:0006508 192 0.039
negative regulation of gene expression GO:0010629 387 0.039
intracellular protein transport GO:0006886 104 0.039
response to abiotic stimulus GO:0009628 341 0.039
regulation of catabolic process GO:0009894 170 0.036
Yeast
smad protein import into nucleus GO:0007184 11 0.036
response to organic substance GO:0010033 284 0.035
negative regulation of cellular component organization GO:0051129 108 0.035
regulation of purine nucleotide metabolic process GO:1900542 62 0.035
Yeast
protein targeting GO:0006605 64 0.034
nucleoside phosphate metabolic process GO:0006753 162 0.033
Yeast
mitotic sister chromatid separation GO:0051306 30 0.033
single organism catabolic process GO:0044712 228 0.032
Yeast
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.032
Yeast
purine nucleoside triphosphate metabolic process GO:0009144 119 0.032
Yeast
cell proliferation GO:0008283 299 0.032
positive regulation of rna biosynthetic process GO:1902680 266 0.032
regulation of nucleotide catabolic process GO:0030811 48 0.032
Yeast
protein localization GO:0008104 284 0.031
response to biotic stimulus GO:0009607 294 0.031
response to external biotic stimulus GO:0043207 293 0.031
larval development GO:0002164 104 0.031
Worm
vesicle mediated transport GO:0016192 381 0.031
cytoplasmic transport GO:0016482 130 0.030
purine ribonucleotide catabolic process GO:0009154 109 0.030
Yeast
dendrite morphogenesis GO:0048813 199 0.029
response to light stimulus GO:0009416 124 0.029
purine ribonucleotide metabolic process GO:0009150 145 0.029
Yeast
organonitrogen compound catabolic process GO:1901565 128 0.029
Yeast
ribonucleoside metabolic process GO:0009119 127 0.029
Yeast
endocytosis GO:0006897 310 0.029
positive regulation of hydrolase activity GO:0051345 78 0.028
regulation of chromosome organization GO:0033044 64 0.028
purine nucleotide metabolic process GO:0006163 146 0.028
Yeast
single organism intracellular transport GO:1902582 207 0.027
nucleoside catabolic process GO:0009164 112 0.027
Yeast
mitotic chromosome condensation GO:0007076 22 0.026
regulation of mitotic spindle organization GO:0060236 9 0.026
mitotic spindle organization GO:0007052 220 0.026
nucleoside phosphate catabolic process GO:1901292 110 0.026
Yeast
nuclear division GO:0000280 332 0.026
establishment of localization in cell GO:0051649 402 0.026
regulation of hydrolase activity GO:0051336 97 0.026
Yeast
female meiotic division GO:0007143 70 0.026
mitotic sister chromatid segregation GO:0000070 87 0.025
g1 s transition of mitotic cell cycle GO:0000082 31 0.025
establishment of protein localization GO:0045184 163 0.025
cell fate determination GO:0001709 91 0.025
heterocycle catabolic process GO:0046700 166 0.024
Yeast
regulation of chromatin silencing GO:0031935 36 0.024
positive regulation of macromolecule metabolic process GO:0010604 405 0.024
post embryonic appendage morphogenesis GO:0035120 385 0.024
g2 dna damage checkpoint GO:0031572 69 0.024
hindgut morphogenesis GO:0007442 58 0.024
cellular nitrogen compound catabolic process GO:0044270 165 0.023
Yeast
regulation of cell cycle process GO:0010564 181 0.023
secretion GO:0046903 109 0.023
carbohydrate derivative catabolic process GO:1901136 118 0.023
Yeast
glycosyl compound metabolic process GO:1901657 127 0.023
Yeast
negative regulation of cell cycle GO:0045786 116 0.022
nucleotide catabolic process GO:0009166 109 0.022
Yeast
regulation of protein metabolic process GO:0051246 256 0.021
regulation of mitotic sister chromatid segregation GO:0033047 28 0.021
mitotic sister chromatid cohesion GO:0007064 6 0.021
organonitrogen compound metabolic process GO:1901564 318 0.021
Yeast
purine nucleoside triphosphate catabolic process GO:0009146 108 0.020
Yeast
ribose phosphate metabolic process GO:0019693 145 0.020
Yeast
germarium derived female germ line cyst formation GO:0030727 42 0.020
apoptotic process GO:0006915 159 0.020
spindle checkpoint GO:0031577 11 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
Yeast
regulation of cytoskeleton organization GO:0051493 89 0.020
positive regulation of cellular biosynthetic process GO:0031328 316 0.020
reproductive system development GO:0061458 74 0.020
Worm
regulation of gtpase activity GO:0043087 44 0.020
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.020
regulation of nucleotide metabolic process GO:0006140 62 0.020
Yeast
regulation of phosphorus metabolic process GO:0051174 210 0.020
Yeast
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.019
regulation of programmed cell death GO:0043067 152 0.019
female meiosis chromosome segregation GO:0016321 33 0.019
negative regulation of cell cycle phase transition GO:1901988 103 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.019
regulation of protein complex disassembly GO:0043244 29 0.019
negative regulation of purine nucleotide catabolic process GO:0033122 1 0.019
Yeast
regulation of cellular amine metabolic process GO:0033238 3 0.019
neuronal stem cell maintenance GO:0097150 4 0.018
mitotic g2 dna damage checkpoint GO:0007095 69 0.018
locomotory behavior GO:0007626 176 0.018
ribonucleoside triphosphate catabolic process GO:0009203 108 0.018
Yeast
regulation of cellular localization GO:0060341 136 0.018
germ line cyst formation GO:0048134 44 0.018
defense response GO:0006952 300 0.018
cell motility GO:0048870 251 0.018
ribonucleotide metabolic process GO:0009259 145 0.017
Yeast
positive regulation of molecular function GO:0044093 136 0.017
organic substance transport GO:0071702 257 0.017
regulation of dna dependent dna replication GO:0090329 6 0.017
regulation of mitotic sister chromatid separation GO:0010965 28 0.017
single organism behavior GO:0044708 391 0.017
digestive system development GO:0055123 149 0.016
response to heat GO:0009408 63 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
nitrogen compound transport GO:0071705 85 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
Yeast
protein maturation GO:0051604 71 0.016
regulation of transport GO:0051049 181 0.016
chromatin remodeling GO:0006338 72 0.016
regulation of purine nucleotide catabolic process GO:0033121 48 0.016
Yeast
centriole replication GO:0007099 24 0.016
histone h2a acetylation GO:0043968 1 0.016
regulation of microtubule cytoskeleton organization GO:0070507 41 0.016
nucleoside triphosphate metabolic process GO:0009141 120 0.016
Yeast
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.016
Yeast
protein processing GO:0016485 68 0.016
regulation of mitosis GO:0007088 56 0.015
forebrain development GO:0030900 2 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
response to other organism GO:0051707 293 0.015
single organism membrane organization GO:0044802 93 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
cell cycle g1 s phase transition GO:0044843 31 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
cellular amine metabolic process GO:0044106 12 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
Yeast
actin filament based process GO:0030029 220 0.014
mitotic g2 m transition checkpoint GO:0044818 70 0.014
catabolic process GO:0009056 409 0.014
Yeast
protein complex biogenesis GO:0070271 201 0.014
regulation of proteolysis GO:0030162 87 0.014
body morphogenesis GO:0010171 2 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
positive regulation of proteolysis GO:0045862 52 0.014
protein dna complex assembly GO:0065004 63 0.014
Yeast
protein import GO:0017038 55 0.014
negative regulation of nucleotide metabolic process GO:0045980 4 0.014
Yeast
appendage morphogenesis GO:0035107 397 0.014
purine containing compound catabolic process GO:0072523 112 0.014
Yeast
regulation of sister chromatid segregation GO:0033045 28 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
negative regulation of proteolysis GO:0045861 31 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
Yeast
cell division GO:0051301 248 0.013
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
Yeast
cellular response to molecule of bacterial origin GO:0071219 3 0.013
response to fungus GO:0009620 50 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
striated muscle tissue development GO:0014706 27 0.012
rna processing GO:0006396 147 0.012
programmed cell death GO:0012501 257 0.012
response to bacterium GO:0009617 198 0.012
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.012
gtp catabolic process GO:0006184 72 0.012
epithelial cell differentiation GO:0030855 322 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.012
macromolecular complex disassembly GO:0032984 37 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
regulation of gtp catabolic process GO:0033124 44 0.012
tube development GO:0035295 244 0.012
defense response to gram negative bacterium GO:0050829 94 0.012
tube morphogenesis GO:0035239 191 0.012
rna 3 end processing GO:0031123 45 0.012
development of primary sexual characteristics GO:0045137 50 0.011
Worm
actin cytoskeleton organization GO:0030036 206 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
posttranscriptional gene silencing GO:0016441 46 0.011
gtp metabolic process GO:0046039 72 0.011
organelle fission GO:0048285 340 0.011
nuclear transport GO:0051169 72 0.011
response to lipopolysaccharide GO:0032496 4 0.011
dna biosynthetic process GO:0071897 24 0.011
endomembrane system organization GO:0010256 119 0.011
tissue morphogenesis GO:0048729 297 0.011
vesicle organization GO:0016050 44 0.011
regulation of nucleoside metabolic process GO:0009118 50 0.011
Yeast
maintenance of location GO:0051235 73 0.011
microtubule organizing center organization GO:0031023 168 0.011
microtubule based movement GO:0007018 51 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
secretion by cell GO:0032940 101 0.011
female germ line cyst formation GO:0048135 42 0.011
phagocytosis GO:0006909 215 0.011
cellular catabolic process GO:0044248 372 0.010
Yeast
cellular protein modification process GO:0006464 438 0.010
mrna 3 end processing GO:0031124 28 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
regulation of cellular protein metabolic process GO:0032268 243 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
Yeast

Mcm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.011