Drosophila melanogaster

95 known processes

faf (Dmel_CG1945)

fat facets

(Aliases: BcDNA.LD22582,Dmel\CG1945,Faf,BcDNA:LD22582,CG1945)

faf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuromuscular junction development GO:0007528 149 0.898
synapse organization GO:0050808 196 0.889
synaptic vesicle exocytosis GO:0016079 16 0.846
neurotransmitter transport GO:0006836 37 0.765
tube morphogenesis GO:0035239 191 0.704
neurotransmitter secretion GO:0007269 35 0.605
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.584
cell motility GO:0048870 251 0.581
Human Mouse
organelle localization GO:0051640 148 0.532
imaginal disc derived appendage morphogenesis GO:0035114 395 0.506
synaptic transmission GO:0007268 288 0.496
tube development GO:0035295 244 0.436
cellularization GO:0007349 90 0.432
establishment of protein localization GO:0045184 163 0.432
signal release GO:0023061 49 0.431
synaptic vesicle transport GO:0048489 50 0.428
intracellular signal transduction GO:0035556 300 0.426
associative learning GO:0008306 65 0.375
regulation of protein metabolic process GO:0051246 256 0.338
regulation of vesicle mediated transport GO:0060627 59 0.311
negative regulation of synapse assembly GO:0051964 39 0.291
positive regulation of cell motility GO:2000147 3 0.291
negative regulation of cellular metabolic process GO:0031324 382 0.284
wing disc morphogenesis GO:0007472 344 0.281
negative regulation of cell communication GO:0010648 223 0.279
regulation of transport GO:0051049 181 0.278
negative regulation of neurogenesis GO:0050768 53 0.273
positive regulation of developmental process GO:0051094 143 0.265
regulation of intracellular signal transduction GO:1902531 236 0.262
regulation of multicellular organismal development GO:2000026 414 0.262
negative regulation of cell development GO:0010721 62 0.257
establishment of synaptic vesicle localization GO:0097480 50 0.252
posttranscriptional regulation of gene expression GO:0010608 145 0.243
axonogenesis GO:0007409 290 0.240
Human Mouse
regulation of synapse organization GO:0050807 110 0.231
embryonic development via the syncytial blastoderm GO:0001700 148 0.223
regulation of embryonic development GO:0045995 68 0.212
localization of cell GO:0051674 257 0.210
Human Mouse
regulation of molecular function GO:0065009 217 0.209
regulation of synapse assembly GO:0051963 94 0.205
response to radiation GO:0009314 155 0.204
positive regulation of cell migration GO:0030335 2 0.202
imaginal disc derived wing morphogenesis GO:0007476 337 0.201
exocytosis GO:0006887 28 0.199
appendage development GO:0048736 401 0.197
regulation of cellular localization GO:0060341 136 0.195
regulation of growth GO:0040008 233 0.193
establishment of localization in cell GO:0051649 402 0.190
regulation of cellular component biogenesis GO:0044087 201 0.189
cell death GO:0008219 279 0.185
epithelium migration GO:0090132 148 0.185
embryo development ending in birth or egg hatching GO:0009792 152 0.184
Mouse
compound eye development GO:0048749 307 0.183
regulation of neural precursor cell proliferation GO:2000177 35 0.180
digestive tract morphogenesis GO:0048546 127 0.172
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.163
positive regulation of nervous system development GO:0051962 69 0.158
synaptic growth at neuromuscular junction GO:0051124 119 0.158
germ cell migration GO:0008354 43 0.156
regulation of cell development GO:0060284 215 0.153
programmed cell death GO:0012501 257 0.148
neuroblast proliferation GO:0007405 74 0.147
tissue migration GO:0090130 155 0.147
regulation of anatomical structure morphogenesis GO:0022603 242 0.144
regulation of protein complex assembly GO:0043254 42 0.143
synaptic vesicle localization GO:0097479 53 0.142
axon development GO:0061564 297 0.139
Human Mouse
post embryonic appendage morphogenesis GO:0035120 385 0.137
regulation of neurotransmitter levels GO:0001505 38 0.136
imaginal disc derived appendage development GO:0048737 399 0.135
tissue morphogenesis GO:0048729 297 0.134
regulation of localization GO:0032879 275 0.133
secretion by cell GO:0032940 101 0.132
negative regulation of nervous system development GO:0051961 92 0.132
appendage morphogenesis GO:0035107 397 0.130
formation of primary germ layer GO:0001704 24 0.130
epithelial cell migration GO:0010631 148 0.115
hair cell differentiation GO:0035315 47 0.114
chaeta development GO:0022416 97 0.114
protein localization GO:0008104 284 0.111
positive regulation of cellular component organization GO:0051130 156 0.111
negative regulation of cell differentiation GO:0045596 143 0.109
positive regulation of cell differentiation GO:0045597 64 0.108
embryonic morphogenesis GO:0048598 206 0.105
compound eye morphogenesis GO:0001745 249 0.102
regulation of neuron projection development GO:0010975 69 0.101
vesicle mediated transport GO:0016192 381 0.100
regulation of catalytic activity GO:0050790 185 0.100
cell maturation GO:0048469 144 0.097
regulation of immune system process GO:0002682 176 0.096
macromolecule catabolic process GO:0009057 161 0.095
regulation of synaptic transmission GO:0050804 69 0.091
synaptic vesicle recycling GO:0036465 28 0.086
death GO:0016265 284 0.085
negative regulation of signaling GO:0023057 219 0.084
axon guidance GO:0007411 233 0.084
catabolic process GO:0009056 409 0.080
hindbrain development GO:0030902 2 0.079
Mouse
central nervous system development GO:0007417 201 0.077
Mouse
lipid localization GO:0010876 54 0.075
intracellular transport GO:0046907 228 0.074
mitotic dna integrity checkpoint GO:0044774 75 0.074
regulation of small gtpase mediated signal transduction GO:0051056 93 0.071
cellular nitrogen compound catabolic process GO:0044270 165 0.067
cell proliferation GO:0008283 299 0.066
sex differentiation GO:0007548 81 0.065
small molecule metabolic process GO:0044281 305 0.064
neuron maturation GO:0042551 31 0.064
regulation of phosphorus metabolic process GO:0051174 210 0.062
positive regulation of catabolic process GO:0009896 105 0.062
regulation of anatomical structure size GO:0090066 163 0.061
vesicle localization GO:0051648 55 0.059
organic cyclic compound catabolic process GO:1901361 168 0.058
regulation of cell death GO:0010941 173 0.057
dna templated transcription elongation GO:0006354 18 0.057
regulation of secretion by cell GO:1903530 39 0.057
epithelial cell differentiation GO:0030855 322 0.057
maintenance of location GO:0051235 73 0.056
response to transforming growth factor beta GO:0071559 18 0.056
Human Mouse
erbb signaling pathway GO:0038127 58 0.055
synapse assembly GO:0007416 143 0.052
regulation of phosphate metabolic process GO:0019220 210 0.051
purine ribonucleotide metabolic process GO:0009150 145 0.051
regulation of phosphorylation GO:0042325 147 0.050
cell migration GO:0016477 238 0.050
Human Mouse
positive regulation of response to stimulus GO:0048584 323 0.050
wnt signaling pathway GO:0016055 98 0.049
secretion GO:0046903 109 0.049
regulation of cell differentiation GO:0045595 302 0.048
actin filament based process GO:0030029 220 0.048
regulation of developmental growth GO:0048638 174 0.048
negative regulation of cell proliferation GO:0008285 69 0.047
developmental maturation GO:0021700 172 0.046
response to starvation GO:0042594 97 0.046
positive regulation of multicellular organismal process GO:0051240 143 0.045
synaptic vesicle endocytosis GO:0048488 28 0.045
male gamete generation GO:0048232 201 0.045
eye morphogenesis GO:0048592 260 0.044
negative regulation of response to stimulus GO:0048585 258 0.044
spermatid differentiation GO:0048515 114 0.043
positive regulation of growth GO:0045927 75 0.043
actin filament bundle assembly GO:0051017 26 0.042
response to light stimulus GO:0009416 124 0.041
positive regulation of secretion GO:0051047 22 0.041
apical junction assembly GO:0043297 32 0.041
negative regulation of cellular biosynthetic process GO:0031327 277 0.040
development of primary sexual characteristics GO:0045137 50 0.039
establishment of vesicle localization GO:0051650 51 0.039
cellular macromolecular complex assembly GO:0034622 153 0.038
positive regulation of neurogenesis GO:0050769 41 0.038
asymmetric cell division GO:0008356 37 0.037
cellular response to extracellular stimulus GO:0031668 64 0.036
dorsal closure GO:0007391 79 0.036
organelle fission GO:0048285 340 0.036
cell cycle phase transition GO:0044770 140 0.035
cell growth GO:0016049 108 0.035
Human Mouse
negative regulation of protein metabolic process GO:0051248 85 0.035
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.035
positive regulation of cellular catabolic process GO:0031331 95 0.035
regulation of ras protein signal transduction GO:0046578 93 0.034
endocytosis GO:0006897 310 0.034
reproductive structure development GO:0048608 74 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.034
positive regulation of signal transduction GO:0009967 223 0.033
cellular response to endogenous stimulus GO:0071495 80 0.033
Human Mouse
negative regulation of mapk cascade GO:0043409 23 0.033
cellular macromolecule localization GO:0070727 220 0.033
regulation of catabolic process GO:0009894 170 0.032
regulation of cell migration GO:0030334 22 0.032
cellular protein localization GO:0034613 160 0.032
lamellipodium organization GO:0097581 21 0.032
regulation of synaptic vesicle exocytosis GO:2000300 3 0.032
eye development GO:0001654 323 0.032
mrna metabolic process GO:0016071 124 0.032
regulation of nervous system development GO:0051960 248 0.031
regulation of cytoskeleton organization GO:0051493 89 0.031
developmental programmed cell death GO:0010623 138 0.031
positive regulation of cell communication GO:0010647 250 0.030
neuron projection guidance GO:0097485 241 0.030
actin filament organization GO:0007015 126 0.029
positive regulation of signaling GO:0023056 243 0.028
skin development GO:0043588 65 0.028
regulation of wnt signaling pathway GO:0030111 68 0.028
neural precursor cell proliferation GO:0061351 75 0.028
positive regulation of catalytic activity GO:0043085 118 0.028
proteolysis GO:0006508 192 0.027
cellular response to dna damage stimulus GO:0006974 223 0.027
regulation of cellular protein metabolic process GO:0032268 243 0.027
positive regulation of transport GO:0051050 92 0.027
purine nucleoside triphosphate catabolic process GO:0009146 108 0.027
ameboidal type cell migration GO:0001667 151 0.027
regulation of embryonic cell shape GO:0016476 30 0.026
phosphorylation GO:0016310 294 0.026
positive regulation of cell adhesion GO:0045785 10 0.026
developmental growth GO:0048589 280 0.026
Human Mouse
camera type eye morphogenesis GO:0048593 2 0.026
meiotic nuclear division GO:0007126 151 0.026
positive regulation of cell development GO:0010720 61 0.025
brain development GO:0007420 120 0.025
Mouse
eye photoreceptor cell fate commitment GO:0042706 37 0.025
glial cell differentiation GO:0010001 35 0.024
regulation of cellular catabolic process GO:0031329 157 0.024
reproductive system development GO:0061458 74 0.024
nucleoside catabolic process GO:0009164 112 0.024
head involution GO:0008258 35 0.024
small gtpase mediated signal transduction GO:0007264 88 0.024
regulation of programmed cell death GO:0043067 152 0.024
response to organic cyclic compound GO:0014070 89 0.024
regulation of phosphatase activity GO:0010921 3 0.024
response to nutrient levels GO:0031667 114 0.023
negative regulation of signal transduction GO:0009968 206 0.023
actin filament bundle organization GO:0061572 28 0.023
positive regulation of rna metabolic process GO:0051254 271 0.023
cognition GO:0050890 141 0.023
regulation of hydrolase activity GO:0051336 97 0.022
purine nucleoside catabolic process GO:0006152 112 0.022
lipid storage GO:0019915 38 0.022
mapk cascade GO:0000165 107 0.022
regulation of mapk cascade GO:0043408 92 0.022
ion transport GO:0006811 145 0.022
negative regulation of biosynthetic process GO:0009890 277 0.022
regulation of actin filament based process GO:0032970 42 0.022
response to organic substance GO:0010033 284 0.022
Human Mouse
purine ribonucleoside metabolic process GO:0046128 127 0.021
nuclear division GO:0000280 332 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
negative regulation of multicellular organismal process GO:0051241 142 0.020
immune response GO:0006955 246 0.020
dna metabolic process GO:0006259 227 0.019
response to abiotic stimulus GO:0009628 341 0.019
somatic muscle development GO:0007525 66 0.019
organic substance catabolic process GO:1901575 308 0.019
immune response activating signal transduction GO:0002757 2 0.019
regulation of intracellular transport GO:0032386 64 0.019
regulation of cellular component movement GO:0051270 42 0.019
ribonucleotide catabolic process GO:0009261 109 0.018
regulation of actin cytoskeleton organization GO:0032956 42 0.018
extrinsic apoptotic signaling pathway GO:0097191 1 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
chaeta morphogenesis GO:0008407 42 0.018
negative regulation of developmental process GO:0051093 201 0.018
regulation of hemocyte proliferation GO:0035206 37 0.018
regulation of organelle organization GO:0033043 196 0.018
gastrulation GO:0007369 70 0.017
chromosome segregation GO:0007059 157 0.017
oxidation reduction process GO:0055114 123 0.017
positive regulation of cell proliferation GO:0008284 47 0.017
regulation of mitotic cell cycle GO:0007346 190 0.017
respiratory system development GO:0060541 213 0.017
heterocycle catabolic process GO:0046700 166 0.017
pole cell development GO:0007277 26 0.017
regulation of protein localization GO:0032880 76 0.017
sensory organ morphogenesis GO:0090596 260 0.017
energy derivation by oxidation of organic compounds GO:0015980 32 0.017
single organism biosynthetic process GO:0044711 206 0.017
cellular response to inorganic substance GO:0071241 8 0.017
regulation of synaptic vesicle endocytosis GO:1900242 7 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
single organism catabolic process GO:0044712 228 0.017
organophosphate catabolic process GO:0046434 112 0.017
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.016
determination of adult lifespan GO:0008340 137 0.016
anterior posterior axis specification embryo GO:0008595 103 0.016
regulation of cell shape GO:0008360 113 0.016
synaptic transmission gabaergic GO:0051932 1 0.016
modification dependent protein catabolic process GO:0019941 78 0.016
regulation of erbb signaling pathway GO:1901184 42 0.016
organ growth GO:0035265 56 0.016
divalent metal ion transport GO:0070838 26 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
regulation of synapse structure and activity GO:0050803 128 0.016
positive regulation of phosphate metabolic process GO:0045937 139 0.016
response to endogenous stimulus GO:0009719 119 0.015
Human Mouse
cell recognition GO:0008037 102 0.015
regulation of steroid metabolic process GO:0019218 2 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.015
organonitrogen compound metabolic process GO:1901564 318 0.015
regulation of actin filament polymerization GO:0030833 25 0.015
macromolecular complex assembly GO:0065003 256 0.015
aromatic compound catabolic process GO:0019439 166 0.015
oocyte axis specification GO:0007309 108 0.015
cellular protein modification process GO:0006464 438 0.015
negative regulation of cellular component organization GO:0051129 108 0.015
regulation of protein kinase activity GO:0045859 51 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
regulation of cellular component size GO:0032535 98 0.015
response to extracellular stimulus GO:0009991 116 0.015
cell cell junction assembly GO:0007043 38 0.014
telencephalon development GO:0021537 2 0.014
Mouse
regulation of establishment of protein localization GO:0070201 61 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
peptidyl threonine phosphorylation GO:0018107 2 0.014
regulation of immune response GO:0050776 118 0.014
positive regulation of endocytosis GO:0045807 22 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
epidermal growth factor receptor signaling pathway GO:0007173 58 0.014
positive regulation of neuron differentiation GO:0045666 26 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.014
response to calcium ion GO:0051592 1 0.014
intracellular protein transport GO:0006886 104 0.013
actin filament polymerization GO:0030041 27 0.013
stress activated mapk cascade GO:0051403 52 0.013
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.013
regulation of cell motility GO:2000145 23 0.013
positive regulation of gene expression GO:0010628 290 0.013
organophosphate metabolic process GO:0019637 195 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
regulation of neurotransmitter secretion GO:0046928 14 0.013
negative regulation of cell death GO:0060548 81 0.013
regulation of locomotion GO:0040012 42 0.013
cell cycle checkpoint GO:0000075 95 0.012
regionalization GO:0003002 416 0.012
neuron neuron synaptic transmission GO:0007270 14 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
amine metabolic process GO:0009308 12 0.012
actin filament based movement GO:0030048 26 0.012
morphogenesis of a polarized epithelium GO:0001738 93 0.012
cellular ketone metabolic process GO:0042180 24 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
protein catabolic process GO:0030163 101 0.012
positive regulation of cell projection organization GO:0031346 29 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
organic substance transport GO:0071702 257 0.012
regulation of cell proliferation GO:0042127 163 0.011
epidermis development GO:0008544 65 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
negative regulation of phosphate metabolic process GO:0045936 45 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
response to inorganic substance GO:0010035 44 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.011
regulation of cell projection assembly GO:0060491 30 0.011
regulation of actin filament length GO:0030832 27 0.011
cellular response to organic substance GO:0071310 132 0.011
Human Mouse
purine nucleoside metabolic process GO:0042278 127 0.011
signal transduction in response to dna damage GO:0042770 3 0.011
apoptotic process GO:0006915 159 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
positive regulation of epithelial cell differentiation GO:0030858 1 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of exocytosis GO:0017157 6 0.011
epithelial cell development GO:0002064 274 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
positive regulation of developmental growth GO:0048639 62 0.011
positive regulation of molecular function GO:0044093 136 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
regulation of mrna metabolic process GO:1903311 72 0.010
positive regulation of nucleotide catabolic process GO:0030813 46 0.010
neuron recognition GO:0008038 101 0.010
anatomical structure homeostasis GO:0060249 97 0.010
cytoskeleton dependent cytokinesis GO:0061640 81 0.010
oocyte maturation GO:0001556 3 0.010
regulation of translation GO:0006417 56 0.010
cuticle pattern formation GO:0035017 27 0.010
spermatogenesis GO:0007283 200 0.010

faf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org