Drosophila melanogaster

13 known processes

shep (Dmel_CG32423)

alan shepard

(Aliases: alan-shepard,CG10668,BcDNA:LD40028,anon-WO0118547.198,alan,cg10668,CG10647,anon-EST:Posey83,Dmel\CG32423,anon-WO0172774.41,CG32423,BcDNA:RH63980,CG10649)

shep biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to gravity GO:0009629 26 0.963
gravitaxis GO:0042332 26 0.914
taxis GO:0042330 304 0.225
neurological system process GO:0050877 358 0.201
response to abiotic stimulus GO:0009628 341 0.200
eye development GO:0001654 323 0.158
sensory organ morphogenesis GO:0090596 260 0.157
negative regulation of cellular biosynthetic process GO:0031327 277 0.130
positive regulation of macromolecule metabolic process GO:0010604 405 0.121
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.114
ion transport GO:0006811 145 0.108
compound eye morphogenesis GO:0001745 249 0.100
eye morphogenesis GO:0048592 260 0.093
negative regulation of gene expression GO:0010629 387 0.092
regulation of protein metabolic process GO:0051246 256 0.091
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.087
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.083
regulation of cell differentiation GO:0045595 302 0.081
positive regulation of rna metabolic process GO:0051254 271 0.079
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.078
circadian rhythm GO:0007623 105 0.077
locomotory behavior GO:0007626 176 0.075
response to organic substance GO:0010033 284 0.074
negative regulation of nucleic acid templated transcription GO:1903507 240 0.071
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.070
dendrite morphogenesis GO:0048813 199 0.069
eye photoreceptor cell differentiation GO:0001754 145 0.067
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.066
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.065
regulation of cellular protein metabolic process GO:0032268 243 0.063
Mouse
appendage development GO:0048736 401 0.063
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.062
dendrite development GO:0016358 204 0.062
growth GO:0040007 359 0.061
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.061
organic substance transport GO:0071702 257 0.060
regulation of mitotic cell cycle GO:0007346 190 0.058
transmembrane transport GO:0055085 139 0.058
positive regulation of nucleic acid templated transcription GO:1903508 266 0.057
negative regulation of rna metabolic process GO:0051253 251 0.057
purine ribonucleotide metabolic process GO:0009150 145 0.057
learning GO:0007612 75 0.056
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.056
rhythmic process GO:0048511 106 0.056
small molecule metabolic process GO:0044281 305 0.056
associative learning GO:0008306 65 0.055
catabolic process GO:0009056 409 0.055
positive regulation of gene expression GO:0010628 290 0.054
Mouse
imaginal disc derived appendage development GO:0048737 399 0.054
negative regulation of rna biosynthetic process GO:1902679 240 0.054
compound eye photoreceptor cell differentiation GO:0001751 140 0.054
phosphorylation GO:0016310 294 0.052
purine containing compound metabolic process GO:0072521 155 0.052
positive regulation of phosphorus metabolic process GO:0010562 139 0.050
imaginal disc derived appendage morphogenesis GO:0035114 395 0.049
carbohydrate derivative metabolic process GO:1901135 217 0.049
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.048
photoreceptor cell differentiation GO:0046530 170 0.048
tissue morphogenesis GO:0048729 297 0.047
appendage morphogenesis GO:0035107 397 0.047
single organism behavior GO:0044708 391 0.046
olfactory learning GO:0008355 56 0.046
regulation of catalytic activity GO:0050790 185 0.045
actin filament based process GO:0030029 220 0.045
regulation of cell morphogenesis GO:0022604 163 0.045
negative regulation of cellular metabolic process GO:0031324 382 0.045
negative regulation of transcription dna templated GO:0045892 237 0.044
developmental growth GO:0048589 280 0.044
positive regulation of transcription dna templated GO:0045893 266 0.044
regulation of molecular function GO:0065009 217 0.044
regulation of phosphate metabolic process GO:0019220 210 0.043
compound eye development GO:0048749 307 0.043
negative regulation of developmental process GO:0051093 201 0.043
chemosensory behavior GO:0007635 106 0.042
wing disc morphogenesis GO:0007472 344 0.042
learning or memory GO:0007611 141 0.041
cellular macromolecule localization GO:0070727 220 0.041
vesicle mediated transport GO:0016192 381 0.041
ion transmembrane transport GO:0034220 122 0.040
positive regulation of response to stimulus GO:0048584 323 0.039
nucleoside phosphate metabolic process GO:0006753 162 0.039
epithelial cell development GO:0002064 274 0.039
establishment of localization in cell GO:0051649 402 0.039
regulation of response to stress GO:0080134 200 0.039
protein localization GO:0008104 284 0.038
negative regulation of response to stimulus GO:0048585 258 0.038
organic substance catabolic process GO:1901575 308 0.038
organonitrogen compound metabolic process GO:1901564 318 0.038
long term memory GO:0007616 62 0.037
regulation of cell shape GO:0008360 113 0.037
single organism biosynthetic process GO:0044711 206 0.037
actin cytoskeleton organization GO:0030036 206 0.036
negative regulation of gene expression epigenetic GO:0045814 77 0.036
endocytosis GO:0006897 310 0.036
camera type eye development GO:0043010 4 0.036
regulation of defense response GO:0031347 102 0.035
positive regulation of biosynthetic process GO:0009891 316 0.035
Mouse
post embryonic appendage morphogenesis GO:0035120 385 0.035
response to oxygen containing compound GO:1901700 200 0.035
response to other organism GO:0051707 293 0.035
positive regulation of molecular function GO:0044093 136 0.035
regulation of catabolic process GO:0009894 170 0.034
regulation of multicellular organismal development GO:2000026 414 0.034
nucleobase containing small molecule metabolic process GO:0055086 174 0.034
cellular protein modification process GO:0006464 438 0.034
gene silencing GO:0016458 138 0.033
regulation of intracellular signal transduction GO:1902531 236 0.033
sensory perception GO:0007600 196 0.033
single organism catabolic process GO:0044712 228 0.032
synaptic transmission GO:0007268 288 0.032
positive regulation of cellular biosynthetic process GO:0031328 316 0.032
Mouse
response to alcohol GO:0097305 95 0.031
positive regulation of catalytic activity GO:0043085 118 0.031
intracellular transport GO:0046907 228 0.031
regulation of localization GO:0032879 275 0.030
protein transport GO:0015031 155 0.030
positive regulation of phosphate metabolic process GO:0045937 139 0.030
positive regulation of cell communication GO:0010647 250 0.030
cytoplasmic transport GO:0016482 130 0.030
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.029
regulation of anatomical structure morphogenesis GO:0022603 242 0.029
digestive system development GO:0055123 149 0.028
intracellular signal transduction GO:0035556 300 0.028
protein modification process GO:0036211 438 0.028
regulation of nucleotide metabolic process GO:0006140 62 0.028
epithelial cell differentiation GO:0030855 322 0.028
negative regulation of signal transduction GO:0009968 206 0.027
response to oxidative stress GO:0006979 86 0.027
positive regulation of signaling GO:0023056 243 0.027
regulation of gene expression epigenetic GO:0040029 128 0.027
positive regulation of catabolic process GO:0009896 105 0.027
regulation of phosphorus metabolic process GO:0051174 210 0.027
behavioral response to ethanol GO:0048149 49 0.027
regulation of cell cycle GO:0051726 291 0.027
imaginal disc derived wing morphogenesis GO:0007476 337 0.027
morphogenesis of an epithelium GO:0002009 276 0.026
memory GO:0007613 94 0.025
establishment or maintenance of cell polarity GO:0007163 167 0.025
ribose phosphate metabolic process GO:0019693 145 0.025
organophosphate metabolic process GO:0019637 195 0.025
actin filament organization GO:0007015 126 0.025
protein phosphorylation GO:0006468 169 0.025
death GO:0016265 284 0.025
organonitrogen compound biosynthetic process GO:1901566 117 0.025
adult behavior GO:0030534 137 0.024
mapk cascade GO:0000165 107 0.024
olfactory behavior GO:0042048 97 0.024
central nervous system development GO:0007417 201 0.024
biological adhesion GO:0022610 138 0.024
tube development GO:0035295 244 0.024
cell growth GO:0016049 108 0.024
nucleoside catabolic process GO:0009164 112 0.024
negative regulation of cell communication GO:0010648 223 0.024
purine nucleotide metabolic process GO:0006163 146 0.024
regulation of cellular catabolic process GO:0031329 157 0.024
cell recognition GO:0008037 102 0.024
organelle fission GO:0048285 340 0.024
regulation of protein modification process GO:0031399 112 0.024
columnar cuboidal epithelial cell development GO:0002066 249 0.023
segmentation GO:0035282 207 0.023
protein complex biogenesis GO:0070271 201 0.023
regulation of multi organism process GO:0043900 131 0.023
macromolecule catabolic process GO:0009057 161 0.022
digestive tract development GO:0048565 149 0.022
nucleotide metabolic process GO:0009117 161 0.022
regulation of immune system process GO:0002682 176 0.022
response to biotic stimulus GO:0009607 294 0.022
cellular catabolic process GO:0044248 372 0.022
cell adhesion GO:0007155 136 0.022
positive regulation of nucleotide metabolic process GO:0045981 55 0.022
synapse organization GO:0050808 196 0.022
gland development GO:0048732 191 0.022
purine containing compound catabolic process GO:0072523 112 0.022
regulation of developmental growth GO:0048638 174 0.022
homeostatic process GO:0042592 199 0.021
heart process GO:0003015 37 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.021
developmental maturation GO:0021700 172 0.021
striated muscle cell differentiation GO:0051146 90 0.021
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.021
negative regulation of signaling GO:0023057 219 0.021
eye photoreceptor cell fate commitment GO:0042706 37 0.021
establishment of protein localization GO:0045184 163 0.021
rhythmic behavior GO:0007622 76 0.021
cyclic nucleotide metabolic process GO:0009187 28 0.021
circadian sleep wake cycle GO:0042745 28 0.021
positive regulation of protein metabolic process GO:0051247 128 0.021
Mouse
single organism intracellular transport GO:1902582 207 0.021
ras protein signal transduction GO:0007265 88 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.021
phagocytosis GO:0006909 215 0.020
cation transport GO:0006812 110 0.020
eye photoreceptor cell development GO:0042462 81 0.020
regulation of neurogenesis GO:0050767 158 0.020
anterior posterior pattern specification GO:0009952 136 0.020
axon development GO:0061564 297 0.020
protein complex assembly GO:0006461 200 0.020
macromolecular complex assembly GO:0065003 256 0.020
neuron recognition GO:0008038 101 0.020
carbohydrate derivative biosynthetic process GO:1901137 85 0.019
immune system process GO:0002376 347 0.019
positive regulation of gtpase activity GO:0043547 43 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
embryonic morphogenesis GO:0048598 206 0.019
regulation of circadian rhythm GO:0042752 49 0.019
chemical homeostasis GO:0048878 92 0.019
axon extension GO:0048675 32 0.019
positive regulation of developmental process GO:0051094 143 0.019
positive regulation of cellular catabolic process GO:0031331 95 0.019
response to nutrient levels GO:0031667 114 0.019
positive regulation of signal transduction GO:0009967 223 0.019
regulation of mitotic cell cycle phase transition GO:1901990 130 0.018
membrane depolarization GO:0051899 4 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
signal transduction by phosphorylation GO:0023014 107 0.018
axis specification GO:0009798 167 0.018
positive regulation of cell motility GO:2000147 3 0.018
positive regulation of rna biosynthetic process GO:1902680 266 0.018
regulation of response to external stimulus GO:0032101 115 0.018
border follicle cell migration GO:0007298 113 0.017
regulation of cell projection organization GO:0031344 92 0.017
defense response to gram negative bacterium GO:0050829 94 0.017
immune response GO:0006955 246 0.017
regulation of purine nucleotide metabolic process GO:1900542 62 0.017
regulation of cell development GO:0060284 215 0.017
renal system development GO:0072001 72 0.017
epithelial tube morphogenesis GO:0060562 88 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
digestive tract morphogenesis GO:0048546 127 0.017
cell proliferation GO:0008283 299 0.017
cellular response to extracellular stimulus GO:0031668 64 0.017
notch signaling pathway GO:0007219 120 0.017
heterocycle catabolic process GO:0046700 166 0.017
cell fate determination GO:0001709 91 0.016
regulation of cellular localization GO:0060341 136 0.016
regulation of gene silencing GO:0060968 63 0.016
organelle localization GO:0051640 148 0.016
regulation of cellular component size GO:0032535 98 0.016
oxoacid metabolic process GO:0043436 103 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
cell maturation GO:0048469 144 0.016
cyclic purine nucleotide metabolic process GO:0052652 25 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
regulation of cell cycle process GO:0010564 181 0.016
hindgut development GO:0061525 58 0.016
purine ribonucleotide catabolic process GO:0009154 109 0.016
kidney development GO:0001822 3 0.016
ameboidal type cell migration GO:0001667 151 0.016
response to external biotic stimulus GO:0043207 293 0.016
regulation of mapk cascade GO:0043408 92 0.016
response to lipopolysaccharide GO:0032496 4 0.016
programmed cell death GO:0012501 257 0.016
response to organic cyclic compound GO:0014070 89 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
regulation of protein transport GO:0051223 57 0.015
positive regulation of nucleoside metabolic process GO:0045979 47 0.015
chromatin silencing GO:0006342 76 0.015
g protein coupled receptor signaling pathway GO:0007186 136 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
heart contraction GO:0060047 26 0.015
aromatic compound catabolic process GO:0019439 166 0.015
regulation of apoptotic process GO:0042981 130 0.015
salivary gland development GO:0007431 162 0.015
localization of cell GO:0051674 257 0.015
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
multicellular organism growth GO:0035264 46 0.015
apoptotic process GO:0006915 159 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
response to ethanol GO:0045471 59 0.015
nucleotide catabolic process GO:0009166 109 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
organophosphate catabolic process GO:0046434 112 0.015
ovarian follicle cell development GO:0030707 248 0.015
cell type specific apoptotic process GO:0097285 38 0.015
regulation of cell proliferation GO:0042127 163 0.015
mitotic nuclear division GO:0007067 213 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
ovarian follicle cell migration GO:0007297 121 0.015
photoreceptor cell fate commitment GO:0046552 41 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
renal tubule development GO:0061326 64 0.015
regulation of synapse structure and activity GO:0050803 128 0.014
sensory perception of mechanical stimulus GO:0050954 72 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
regionalization GO:0003002 416 0.014
nuclear division GO:0000280 332 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
oocyte axis specification GO:0007309 108 0.014
nitrogen compound transport GO:0071705 85 0.014
regulation of organelle organization GO:0033043 196 0.014
cell division GO:0051301 248 0.014
cellular response to biotic stimulus GO:0071216 4 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
regulation of transport GO:0051049 181 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
detection of stimulus GO:0051606 156 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.014
Mouse
cellular protein localization GO:0034613 160 0.014
chromosome organization GO:0051276 360 0.013
response to heat GO:0009408 63 0.013
negative regulation of apoptotic process GO:0043066 63 0.013
regulation of cellular response to stress GO:0080135 89 0.013
regulation of hydrolase activity GO:0051336 97 0.013
positive regulation of cell migration GO:0030335 2 0.013
gliogenesis GO:0042063 80 0.013
positive regulation of synaptic transmission GO:0050806 15 0.013
salivary gland morphogenesis GO:0007435 145 0.013
regulation of gtp catabolic process GO:0033124 44 0.013
endomembrane system organization GO:0010256 119 0.013
single organism cellular localization GO:1902580 180 0.013
organic acid metabolic process GO:0006082 103 0.013
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.013
regulation of programmed cell death GO:0043067 152 0.013
intracellular protein transport GO:0006886 104 0.013
compound eye photoreceptor development GO:0042051 78 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
response to starvation GO:0042594 97 0.013
stem cell differentiation GO:0048863 117 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
response to bacterium GO:0009617 198 0.013
epithelial cell migration GO:0010631 148 0.012
renal tubule morphogenesis GO:0061333 44 0.012
regulation of humoral immune response GO:0002920 51 0.012
dna metabolic process GO:0006259 227 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
r7 cell fate commitment GO:0007465 12 0.012
regulation of circadian sleep wake cycle GO:0042749 25 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.012
establishment of organelle localization GO:0051656 122 0.012
histolysis GO:0007559 102 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
regulation of cytoskeleton organization GO:0051493 89 0.012
lateral inhibition GO:0046331 206 0.012
regulation of purine nucleotide catabolic process GO:0033121 48 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
circadian behavior GO:0048512 76 0.012
forebrain development GO:0030900 2 0.012
multi organism behavior GO:0051705 175 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
cell projection assembly GO:0030031 94 0.012
axonogenesis GO:0007409 290 0.012
response to organonitrogen compound GO:0010243 75 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
cation transmembrane transport GO:0098655 88 0.012
camera type eye morphogenesis GO:0048593 2 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
axon guidance GO:0007411 233 0.011
mitotic spindle organization GO:0007052 220 0.011
regulation of antimicrobial humoral response GO:0002759 50 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
positive regulation of developmental growth GO:0048639 62 0.011
anatomical structure homeostasis GO:0060249 97 0.011
nucleoside phosphate biosynthetic process GO:1901293 34 0.011
regulation of neuron differentiation GO:0045664 103 0.011
response to nitrogen compound GO:1901698 90 0.011
regulation of behavior GO:0050795 75 0.011
gland morphogenesis GO:0022612 145 0.011
regulation of anatomical structure size GO:0090066 163 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
regulation of nucleotide catabolic process GO:0030811 48 0.011
cellular amine metabolic process GO:0044106 12 0.011
cell death GO:0008219 279 0.011
response to decreased oxygen levels GO:0036293 58 0.011
intraspecies interaction between organisms GO:0051703 4 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.011
regulation of endocytosis GO:0030100 37 0.011
protein ubiquitination GO:0016567 70 0.011
antimicrobial humoral response GO:0019730 99 0.011
negative regulation of organelle organization GO:0010639 56 0.011
regulation of immune response GO:0050776 118 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
negative regulation of cell death GO:0060548 81 0.011
regulation of neuron projection development GO:0010975 69 0.011
peptidyl amino acid modification GO:0018193 105 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
blastoderm segmentation GO:0007350 159 0.011
protein modification by small protein conjugation GO:0032446 79 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
regulation of neuron death GO:1901214 26 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
regulation of growth GO:0040008 233 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
defense response GO:0006952 300 0.011
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.011
embryonic pattern specification GO:0009880 174 0.011
regulation of gtpase activity GO:0043087 44 0.011
cellular homeostasis GO:0019725 80 0.011
photoreceptor cell development GO:0042461 96 0.010
autophagic cell death GO:0048102 83 0.010
cell cycle phase transition GO:0044770 140 0.010
ribonucleoside catabolic process GO:0042454 112 0.010
ubiquitin dependent protein catabolic process GO:0006511 78 0.010
cortical cytoskeleton organization GO:0030865 29 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
tissue migration GO:0090130 155 0.010
neuron projection guidance GO:0097485 241 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
tissue death GO:0016271 102 0.010
salivary gland histolysis GO:0035070 88 0.010
peptide metabolic process GO:0006518 80 0.010
nucleoside triphosphate catabolic process GO:0009143 108 0.010
response to temperature stimulus GO:0009266 106 0.010
single organism carbohydrate metabolic process GO:0044723 72 0.010
immune effector process GO:0002252 98 0.010
mesenchymal cell development GO:0014031 1 0.010
cellular response to dna damage stimulus GO:0006974 223 0.010
negative regulation of immune system process GO:0002683 50 0.010
glycosyl compound catabolic process GO:1901658 112 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
gtp catabolic process GO:0006184 72 0.010

shep disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.020
cardiovascular system disease DOID:1287 0 0.016
disease of metabolism DOID:0014667 0 0.011