Drosophila melanogaster

64 known processes

Trn (Dmel_CG7398)

Transportin

(Aliases: CG7398,dTRN,TRN,IMPbeta2,Tm,Trn1,Dmel\CG7398)

Trn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular biosynthetic process GO:0031327 277 0.503
organelle assembly GO:0070925 198 0.396
chromatin silencing GO:0006342 76 0.260
negative regulation of cellular metabolic process GO:0031324 382 0.245
mitotic cell cycle checkpoint GO:0007093 88 0.243
regulation of gene expression epigenetic GO:0040029 128 0.232
endocytosis GO:0006897 310 0.212
death GO:0016265 284 0.201
olfactory behavior GO:0042048 97 0.194
posttranscriptional regulation of gene expression GO:0010608 145 0.193
cellular protein modification process GO:0006464 438 0.188
negative regulation of gene expression GO:0010629 387 0.169
single organism behavior GO:0044708 391 0.160
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.155
organelle fission GO:0048285 340 0.152
Yeast
vesicle mediated transport GO:0016192 381 0.150
transcription from rna polymerase ii promoter GO:0006366 368 0.149
regulation of translation GO:0006417 56 0.141
ribonucleoprotein complex biogenesis GO:0022613 31 0.140
embryonic development via the syncytial blastoderm GO:0001700 148 0.133
positive regulation of macromolecule metabolic process GO:0010604 405 0.124
mrna metabolic process GO:0016071 124 0.120
morphogenesis of an epithelium GO:0002009 276 0.115
cell cycle phase transition GO:0044770 140 0.112
negative regulation of cell communication GO:0010648 223 0.111
chromosome organization GO:0051276 360 0.110
organic acid metabolic process GO:0006082 103 0.109
mitotic nuclear division GO:0007067 213 0.109
Yeast
neurological system process GO:0050877 358 0.108
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.106
negative regulation of cell cycle phase transition GO:1901988 103 0.102
positive regulation of biosynthetic process GO:0009891 316 0.101
tube morphogenesis GO:0035239 191 0.101
nuclear division GO:0000280 332 0.100
Yeast
gene silencing GO:0016458 138 0.098
positive regulation of nucleic acid templated transcription GO:1903508 266 0.098
cellular component assembly involved in morphogenesis GO:0010927 151 0.097
regulation of cellular protein metabolic process GO:0032268 243 0.097
imaginal disc derived appendage morphogenesis GO:0035114 395 0.095
apoptotic process GO:0006915 159 0.093
negative regulation of gene expression epigenetic GO:0045814 77 0.089
central nervous system development GO:0007417 201 0.089
negative regulation of response to stimulus GO:0048585 258 0.088
negative regulation of signal transduction GO:0009968 206 0.087
positive regulation of cellular biosynthetic process GO:0031328 316 0.087
positive regulation of transcription dna templated GO:0045893 266 0.081
negative regulation of signaling GO:0023057 219 0.080
macromolecular complex assembly GO:0065003 256 0.080
cellular catabolic process GO:0044248 372 0.079
centrosome cycle GO:0007098 137 0.079
regulation of cell cycle phase transition GO:1901987 130 0.077
positive regulation of rna biosynthetic process GO:1902680 266 0.076
dna damage checkpoint GO:0000077 78 0.075
cell division GO:0051301 248 0.074
ribonucleoprotein complex assembly GO:0022618 23 0.073
post embryonic appendage morphogenesis GO:0035120 385 0.072
ovarian follicle cell development GO:0030707 248 0.072
ovarian follicle cell migration GO:0007297 121 0.072
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.070
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.070
tissue morphogenesis GO:0048729 297 0.069
proteolysis GO:0006508 192 0.068
epithelial cell development GO:0002064 274 0.068
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.067
response to biotic stimulus GO:0009607 294 0.067
protein modification by small protein conjugation or removal GO:0070647 106 0.067
chromatin organization GO:0006325 207 0.067
positive regulation of gene expression GO:0010628 290 0.066
humoral immune response GO:0006959 117 0.066
appendage development GO:0048736 401 0.066
chorion containing eggshell formation GO:0007304 105 0.065
cell death GO:0008219 279 0.061
positive regulation of rna metabolic process GO:0051254 271 0.060
negative regulation of cell cycle GO:0045786 116 0.059
mrna catabolic process GO:0006402 33 0.056
protein modification process GO:0036211 438 0.054
organic substance catabolic process GO:1901575 308 0.053
response to organic substance GO:0010033 284 0.053
embryonic morphogenesis GO:0048598 206 0.053
adult behavior GO:0030534 137 0.052
regulation of cellular catabolic process GO:0031329 157 0.052
imaginal disc derived wing morphogenesis GO:0007476 337 0.050
negative regulation of rna biosynthetic process GO:1902679 240 0.049
regulation of cell cycle process GO:0010564 181 0.048
chemosensory behavior GO:0007635 106 0.048
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.048
intracellular signal transduction GO:0035556 300 0.046
catabolic process GO:0009056 409 0.046
ribonucleoprotein complex subunit organization GO:0071826 28 0.045
regulation of protein metabolic process GO:0051246 256 0.045
mitotic dna integrity checkpoint GO:0044774 75 0.045
regulation of organelle organization GO:0033043 196 0.044
regulation of intracellular signal transduction GO:1902531 236 0.043
dna integrity checkpoint GO:0031570 81 0.041
brain development GO:0007420 120 0.041
negative regulation of biosynthetic process GO:0009890 277 0.041
single organism catabolic process GO:0044712 228 0.040
negative regulation of cell cycle process GO:0010948 109 0.040
cellular response to organic substance GO:0071310 132 0.040
spindle organization GO:0007051 253 0.039
rna splicing via transesterification reactions GO:0000375 73 0.039
mating GO:0007618 120 0.039
imaginal disc derived appendage development GO:0048737 399 0.039
appendage morphogenesis GO:0035107 397 0.039
regulation of proteasomal protein catabolic process GO:0061136 39 0.038
regulation of mitotic cell cycle phase transition GO:1901990 130 0.038
sperm individualization GO:0007291 48 0.037
defense response GO:0006952 300 0.036
defense response to bacterium GO:0042742 178 0.036
chromosome segregation GO:0007059 157 0.036
oxoacid metabolic process GO:0043436 103 0.035
developmental maturation GO:0021700 172 0.035
aggressive behavior GO:0002118 63 0.035
germarium derived egg chamber formation GO:0007293 101 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.034
negative regulation of developmental process GO:0051093 201 0.034
regulation of proteolysis GO:0030162 87 0.034
g2 dna damage checkpoint GO:0031572 69 0.034
anatomical structure homeostasis GO:0060249 97 0.034
negative regulation of protein metabolic process GO:0051248 85 0.034
centrosome duplication GO:0051298 121 0.034
sister chromatid segregation GO:0000819 92 0.034
cell recognition GO:0008037 102 0.033
regulation of response to stress GO:0080134 200 0.033
cell cycle checkpoint GO:0000075 95 0.032
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.032
mitotic cell cycle phase transition GO:0044772 138 0.032
mitotic g2 dna damage checkpoint GO:0007095 69 0.032
response to other organism GO:0051707 293 0.032
cellular macromolecular complex assembly GO:0034622 153 0.032
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.031
columnar cuboidal epithelial cell development GO:0002066 249 0.031
positive regulation of protein metabolic process GO:0051247 128 0.031
negative regulation of cellular protein metabolic process GO:0032269 85 0.030
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.030
rrna processing GO:0006364 3 0.029
positive regulation of apoptotic signaling pathway GO:2001235 4 0.029
reproductive behavior GO:0019098 122 0.029
embryonic pattern specification GO:0009880 174 0.029
defense response to other organism GO:0098542 225 0.028
positive regulation of intracellular signal transduction GO:1902533 116 0.028
multi organism behavior GO:0051705 175 0.028
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.028
programmed cell death GO:0012501 257 0.027
determination of adult lifespan GO:0008340 137 0.027
gene silencing by mirna GO:0035195 22 0.027
eggshell formation GO:0030703 105 0.027
multi multicellular organism process GO:0044706 123 0.027
neuronal stem cell maintenance GO:0097150 4 0.027
eggshell chorion assembly GO:0007306 66 0.026
regulation of apoptotic process GO:0042981 130 0.026
mrna processing GO:0006397 104 0.026
epithelial cell differentiation GO:0030855 322 0.026
regulation of anatomical structure size GO:0090066 163 0.025
mitotic g2 m transition checkpoint GO:0044818 70 0.025
negative regulation of nucleic acid templated transcription GO:1903507 240 0.025
multi organism reproductive behavior GO:0044705 121 0.025
dendrite development GO:0016358 204 0.025
negative regulation of cell differentiation GO:0045596 143 0.024
regulation of catabolic process GO:0009894 170 0.024
protein catabolic process GO:0030163 101 0.024
regulation of multicellular organismal development GO:2000026 414 0.024
lateral inhibition GO:0046331 206 0.024
localization of cell GO:0051674 257 0.024
open tracheal system development GO:0007424 204 0.024
mitotic sister chromatid segregation GO:0000070 87 0.023
head development GO:0060322 135 0.023
regulation of response to external stimulus GO:0032101 115 0.023
negative regulation of cellular component organization GO:0051129 108 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
tissue migration GO:0090130 155 0.022
negative regulation of rna metabolic process GO:0051253 251 0.022
positive regulation of cell communication GO:0010647 250 0.022
cell cell signaling involved in cell fate commitment GO:0045168 210 0.022
regulation of mitosis GO:0007088 56 0.022
phagocytosis GO:0006909 215 0.022
protein processing GO:0016485 68 0.022
epidermal cell differentiation GO:0009913 51 0.022
covalent chromatin modification GO:0016569 106 0.022
peptide metabolic process GO:0006518 80 0.022
cell adhesion GO:0007155 136 0.021
positive regulation of response to stimulus GO:0048584 323 0.021
immune system process GO:0002376 347 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.021
body morphogenesis GO:0010171 2 0.021
negative regulation of mitotic cell cycle GO:0045930 109 0.021
cell migration GO:0016477 238 0.021
mitotic dna damage checkpoint GO:0044773 74 0.021
rna 3 end processing GO:0031123 45 0.020
developmental growth GO:0048589 280 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
negative regulation of immune system process GO:0002683 50 0.020
positive regulation of apoptotic process GO:0043065 47 0.020
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.020
protein k48 linked ubiquitination GO:0070936 3 0.020
dendrite morphogenesis GO:0048813 199 0.019
respiratory system development GO:0060541 213 0.019
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
mitotic spindle elongation GO:0000022 81 0.019
protein maturation GO:0051604 71 0.019
cellular amide metabolic process GO:0043603 80 0.018
nuclear transcribed mrna catabolic process GO:0000956 24 0.018
wing disc morphogenesis GO:0007472 344 0.018
axon guidance GO:0007411 233 0.018
multicellular organismal reproductive behavior GO:0033057 110 0.018
regulation of tube architecture open tracheal system GO:0035152 68 0.018
negative regulation of apoptotic process GO:0043066 63 0.018
regulation of cellular protein catabolic process GO:1903362 44 0.018
circadian behavior GO:0048512 76 0.018
establishment of localization in cell GO:0051649 402 0.017
regulation of peptidase activity GO:0052547 39 0.017
regulation of programmed cell death GO:0043067 152 0.017
protein complex assembly GO:0006461 200 0.017
cell proliferation GO:0008283 299 0.017
response to oxidative stress GO:0006979 86 0.017
regulation of chromosome organization GO:0033044 64 0.017
muscle organ development GO:0007517 127 0.017
regulation of innate immune response GO:0045088 71 0.016
regulation of cell cycle GO:0051726 291 0.016
chromosome separation GO:0051304 42 0.016
negative regulation of proteolysis GO:0045861 31 0.016
mitotic sister chromatid separation GO:0051306 30 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.016
chromatin assembly GO:0031497 48 0.016
epithelial tube morphogenesis GO:0060562 88 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
small molecule metabolic process GO:0044281 305 0.016
cellular protein catabolic process GO:0044257 83 0.016
regulation of localization GO:0032879 275 0.016
salivary gland development GO:0007431 162 0.015
maintenance of location GO:0051235 73 0.015
protein localization GO:0008104 284 0.015
protein phosphorylation GO:0006468 169 0.015
defense response to gram negative bacterium GO:0050829 94 0.015
rna catabolic process GO:0006401 37 0.015
response to abiotic stimulus GO:0009628 341 0.015
mitotic spindle organization GO:0007052 220 0.015
tube development GO:0035295 244 0.015
regulation of production of molecular mediator of immune response GO:0002700 44 0.015
histone modification GO:0016570 106 0.015
negative regulation of protein processing GO:0010955 31 0.015
axon development GO:0061564 297 0.014
positive regulation of signal transduction GO:0009967 223 0.014
growth GO:0040007 359 0.014
spermatogenesis GO:0007283 200 0.014
macromolecule catabolic process GO:0009057 161 0.014
neuron projection guidance GO:0097485 241 0.014
axonogenesis GO:0007409 290 0.014
negative regulation of cell death GO:0060548 81 0.014
response to bacterium GO:0009617 198 0.014
response to external biotic stimulus GO:0043207 293 0.014
biological adhesion GO:0022610 138 0.014
response to lipopolysaccharide GO:0032496 4 0.014
protein modification by small protein conjugation GO:0032446 79 0.013
locomotory behavior GO:0007626 176 0.013
regulation of protein processing GO:0070613 32 0.013
positive regulation of programmed cell death GO:0043068 62 0.013
autophagy GO:0006914 108 0.013
gland development GO:0048732 191 0.013
camera type eye development GO:0043010 4 0.013
chromatin modification GO:0016568 147 0.013
regulation of cell development GO:0060284 215 0.013
cellular ketone metabolic process GO:0042180 24 0.013
homeostatic process GO:0042592 199 0.013
rna processing GO:0006396 147 0.013
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.013
microtubule organizing center organization GO:0031023 168 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
single organism carbohydrate metabolic process GO:0044723 72 0.012
eye development GO:0001654 323 0.012
regulation of cell death GO:0010941 173 0.012
antimicrobial peptide production GO:0002775 46 0.012
embryonic axis specification GO:0000578 107 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
jak stat cascade GO:0007259 49 0.012
morphogenesis of a polarized epithelium GO:0001738 93 0.012
inter male aggressive behavior GO:0002121 60 0.012
negative regulation of developmental growth GO:0048640 64 0.012
regulation of cellular response to stress GO:0080135 89 0.012
cuticle development GO:0042335 86 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
regulation of cell shape GO:0008360 113 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
gene silencing by rna GO:0031047 57 0.012
regulation of mitotic sister chromatid segregation GO:0033047 28 0.012
neuron recognition GO:0008038 101 0.012
smoothened signaling pathway GO:0007224 49 0.012
phosphorylation GO:0016310 294 0.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.012
reproductive structure development GO:0048608 74 0.011
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.011
establishment of ommatidial planar polarity GO:0042067 49 0.011
nuclear pore organization GO:0006999 1 0.011
organonitrogen compound metabolic process GO:1901564 318 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
mesenchymal cell development GO:0014031 1 0.011
notch signaling pathway GO:0007219 120 0.011
meiotic cell cycle GO:0051321 171 0.011
response to endogenous stimulus GO:0009719 119 0.011
exocrine system development GO:0035272 162 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
chromatin assembly or disassembly GO:0006333 52 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
segmentation GO:0035282 207 0.011
negative regulation of protein maturation GO:1903318 31 0.011
centrosome organization GO:0051297 163 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
cell maturation GO:0048469 144 0.011
protein ubiquitination GO:0016567 70 0.010
positive regulation of catabolic process GO:0009896 105 0.010
border follicle cell migration GO:0007298 113 0.010
proteasomal protein catabolic process GO:0010498 59 0.010
feeding behavior GO:0007631 50 0.010
cytoskeleton dependent cytokinesis GO:0061640 81 0.010
organic substance transport GO:0071702 257 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.010
regulation of compound eye cone cell fate specification GO:0042682 4 0.010
compound eye development GO:0048749 307 0.010
sensory organ morphogenesis GO:0090596 260 0.010
negative regulation of programmed cell death GO:0043069 72 0.010
peptidyl amino acid modification GO:0018193 105 0.010
multicellular organism growth GO:0035264 46 0.010
establishment of rna localization GO:0051236 47 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.010
cellular protein localization GO:0034613 160 0.010
metaphase anaphase transition of cell cycle GO:0044784 28 0.010

Trn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.013