Drosophila melanogaster

93 known processes

Clk (Dmel_CG7391)

Clock

(Aliases: dclk,Jerk,CLOCK,CG7391,clk,CLK,Jrk,bHLHe10,dClck,dCLK,dClock,PAS1,jrk,Dmel\CG7391,dCLOCK,dClk,clock,dCLK/JRK)

Clk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
circadian rhythm GO:0007623 105 1.000
rhythmic process GO:0048511 106 0.999
rhythmic behavior GO:0007622 76 0.997
circadian behavior GO:0048512 76 0.987
circadian sleep wake cycle process GO:0022410 24 0.968
single organism behavior GO:0044708 391 0.960
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.901
regulation of circadian sleep wake cycle GO:0042749 25 0.835
locomotory behavior GO:0007626 176 0.796
regulation of circadian rhythm GO:0042752 49 0.751
circadian sleep wake cycle sleep GO:0050802 23 0.736
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.660
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.651
Mouse
sleep GO:0030431 49 0.635
locomotor rhythm GO:0045475 56 0.630
circadian sleep wake cycle GO:0042745 28 0.599
regulation of behavior GO:0050795 75 0.522
response to radiation GO:0009314 155 0.487
Human Zebrafish
transcription from rna polymerase ii promoter GO:0006366 368 0.480
detection of abiotic stimulus GO:0009582 66 0.453
purine containing compound biosynthetic process GO:0072522 30 0.364
g protein coupled receptor signaling pathway GO:0007186 136 0.346
positive regulation of macromolecule metabolic process GO:0010604 405 0.293
regulation of multicellular organismal development GO:2000026 414 0.280
Mouse
photoperiodism GO:0009648 10 0.276
Zebrafish
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.275
Mouse
regulation of localization GO:0032879 275 0.269
Mouse
detection of light stimulus GO:0009583 58 0.255
entrainment of circadian clock GO:0009649 16 0.253
synaptic transmission GO:0007268 288 0.249
negative regulation of cellular metabolic process GO:0031324 382 0.248
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.247
response to light stimulus GO:0009416 124 0.245
Zebrafish
ion transmembrane transport GO:0034220 122 0.240
organonitrogen compound metabolic process GO:1901564 318 0.238
phototransduction GO:0007602 52 0.236
positive regulation of behavior GO:0048520 19 0.227
regulation of cellular localization GO:0060341 136 0.226
Mouse
cellular response to light stimulus GO:0071482 37 0.221
positive regulation of rna biosynthetic process GO:1902680 266 0.217
negative regulation of nucleic acid templated transcription GO:1903507 240 0.214
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.213
Mouse
sensory perception GO:0007600 196 0.206
gliogenesis GO:0042063 80 0.205
positive regulation of biosynthetic process GO:0009891 316 0.200
camp biosynthetic process GO:0006171 17 0.191
negative regulation of rna metabolic process GO:0051253 251 0.190
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.190
Mouse
cyclic nucleotide biosynthetic process GO:0009190 25 0.189
entrainment of circadian clock by photoperiod GO:0043153 9 0.188
regulation of lyase activity GO:0051339 14 0.184
phenol containing compound metabolic process GO:0018958 57 0.181
negative regulation of cellular biosynthetic process GO:0031327 277 0.180
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.180
Mouse
regulation of transport GO:0051049 181 0.178
Mouse
negative regulation of gene expression GO:0010629 387 0.178
Mouse
negative regulation of camp biosynthetic process GO:0030818 3 0.173
secretion GO:0046903 109 0.172
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.171
response to abiotic stimulus GO:0009628 341 0.162
ion transport GO:0006811 145 0.161
cellular amino acid metabolic process GO:0006520 61 0.157
regulation of secretion by cell GO:1903530 39 0.156
Mouse
signal release GO:0023061 49 0.156
Mouse
regulation of r7 cell differentiation GO:0045676 15 0.154
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.153
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.152
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 7 0.151
protein localization GO:0008104 284 0.151
organelle fission GO:0048285 340 0.147
localization of cell GO:0051674 257 0.145
positive regulation of response to stimulus GO:0048584 323 0.142
Human Mouse
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.140
organic substance transport GO:0071702 257 0.137
Mouse
positive regulation of rna metabolic process GO:0051254 271 0.133
establishment of localization in cell GO:0051649 402 0.124
Mouse
regulation of molecular function GO:0065009 217 0.121
Mouse
regulation of protein metabolic process GO:0051246 256 0.120
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.117
modification dependent macromolecule catabolic process GO:0043632 79 0.117
Mouse
eye development GO:0001654 323 0.116
male mating behavior GO:0060179 70 0.114
negative regulation of signal transduction GO:0009968 206 0.114
Mouse
adult behavior GO:0030534 137 0.113
detection of stimulus GO:0051606 156 0.110
cellular homeostasis GO:0019725 80 0.108
epithelial cell differentiation GO:0030855 322 0.107
Mouse
taxis GO:0042330 304 0.106
proteolysis GO:0006508 192 0.102
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.099
regulation of organ morphogenesis GO:2000027 78 0.098
regulation of cell cycle GO:0051726 291 0.097
positive regulation of cyclic nucleotide metabolic process GO:0030801 9 0.097
neuropeptide signaling pathway GO:0007218 45 0.095
cellular response to radiation GO:0071478 52 0.093
Human
neurological system process GO:0050877 358 0.092
protein import GO:0017038 55 0.092
regulation of transmembrane transport GO:0034762 27 0.092
regulation of cellular amine metabolic process GO:0033238 3 0.092
single organism cellular localization GO:1902580 180 0.090
protein transport GO:0015031 155 0.089
response to extracellular stimulus GO:0009991 116 0.088
positive regulation of transcription dna templated GO:0045893 266 0.088
nucleobase containing small molecule metabolic process GO:0055086 174 0.088
protein targeting to nucleus GO:0044744 51 0.087
catabolic process GO:0009056 409 0.085
Mouse
regulation of hormone levels GO:0010817 40 0.085
Mouse
cellular protein modification process GO:0006464 438 0.084
Human Mouse
organic acid transport GO:0015849 18 0.083
response to temperature stimulus GO:0009266 106 0.082
regulation of sequestering of calcium ion GO:0051282 3 0.082
compound eye photoreceptor cell differentiation GO:0001751 140 0.081
positive regulation of multicellular organismal process GO:0051240 143 0.079
regulation of cell development GO:0060284 215 0.079
Mouse
ubiquitin dependent protein catabolic process GO:0006511 78 0.078
Mouse
protein modification process GO:0036211 438 0.076
Human Mouse
regulation of response to external stimulus GO:0032101 115 0.076
Mouse
ribose phosphate metabolic process GO:0019693 145 0.074
single organism biosynthetic process GO:0044711 206 0.074
small molecule metabolic process GO:0044281 305 0.073
regulation of camp biosynthetic process GO:0030817 12 0.073
eye photoreceptor cell differentiation GO:0001754 145 0.073
regulation of protein catabolic process GO:0042176 55 0.073
negative regulation of homeostatic process GO:0032845 2 0.072
cellular amine metabolic process GO:0044106 12 0.072
regulation of tor signaling GO:0032006 21 0.071
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.070
response to alkaloid GO:0043279 26 0.070
ion homeostasis GO:0050801 55 0.070
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 3 0.070
organic substance catabolic process GO:1901575 308 0.069
Mouse
cellular chemical homeostasis GO:0055082 40 0.069
purine containing compound metabolic process GO:0072521 155 0.068
protein catabolic process GO:0030163 101 0.068
Mouse
positive regulation of gene expression GO:0010628 290 0.067
cytoplasmic transport GO:0016482 130 0.066
monocarboxylic acid transport GO:0015718 3 0.066
nuclear division GO:0000280 332 0.066
regulation of mitotic cell cycle GO:0007346 190 0.065
regulation of phosphate metabolic process GO:0019220 210 0.064
eye morphogenesis GO:0048592 260 0.064
establishment of protein localization GO:0045184 163 0.064
transmembrane transport GO:0055085 139 0.064
cellular response to oxidative stress GO:0034599 28 0.063
cellular macromolecule localization GO:0070727 220 0.063
camera type eye development GO:0043010 4 0.063
sensory organ morphogenesis GO:0090596 260 0.062
regulation of synaptic transmission GO:0050804 69 0.061
regulation of reproductive process GO:2000241 54 0.061
response to bacterium GO:0009617 198 0.060
heart process GO:0003015 37 0.060
homeostatic process GO:0042592 199 0.060
negative regulation of nucleotide biosynthetic process GO:0030809 3 0.059
negative regulation of developmental process GO:0051093 201 0.059
regulation of anatomical structure morphogenesis GO:0022603 242 0.059
regulation of catalytic activity GO:0050790 185 0.058
positive regulation of signal transduction GO:0009967 223 0.058
negative regulation of cell communication GO:0010648 223 0.058
Mouse
intracellular transport GO:0046907 228 0.057
regulation of secretion GO:0051046 44 0.056
Mouse
axonogenesis GO:0007409 290 0.056
cellular ketone metabolic process GO:0042180 24 0.055
deactivation of rhodopsin mediated signaling GO:0016059 17 0.055
compound eye development GO:0048749 307 0.055
endocytosis GO:0006897 310 0.055
phototaxis GO:0042331 21 0.055
axon guidance GO:0007411 233 0.054
regulation of nucleotide metabolic process GO:0006140 62 0.054
adult locomotory behavior GO:0008344 76 0.054
cellular response to chemical stimulus GO:0070887 199 0.054
negative regulation of transcription dna templated GO:0045892 237 0.054
Mouse
head development GO:0060322 135 0.053
photoreceptor cell differentiation GO:0046530 170 0.053
positive regulation of cell differentiation GO:0045597 64 0.053
response to nitrogen compound GO:1901698 90 0.053
eye photoreceptor cell development GO:0042462 81 0.053
nuclear import GO:0051170 51 0.052
modification dependent protein catabolic process GO:0019941 78 0.052
Mouse
regulation of lipid metabolic process GO:0019216 15 0.052
secretion by cell GO:0032940 101 0.052
Mouse
heart contraction GO:0060047 26 0.052
central nervous system development GO:0007417 201 0.052
neuron projection guidance GO:0097485 241 0.051
purine ribonucleotide metabolic process GO:0009150 145 0.051
detection of external stimulus GO:0009581 66 0.051
nucleoside phosphate biosynthetic process GO:1901293 34 0.050
protein localization to nucleus GO:0034504 55 0.049
chemical homeostasis GO:0048878 92 0.049
cellular response to insulin stimulus GO:0032869 28 0.049
regulation of camp metabolic process GO:0030814 12 0.049
rhabdomere development GO:0042052 38 0.048
multicellular organismal aging GO:0010259 140 0.048
negative regulation of cyclic nucleotide metabolic process GO:0030800 3 0.048
protein import into nucleus GO:0006606 51 0.047
ribose phosphate biosynthetic process GO:0046390 28 0.047
vesicle mediated transport GO:0016192 381 0.047
axon development GO:0061564 297 0.046
cyclic purine nucleotide metabolic process GO:0052652 25 0.046
regulation of steroid metabolic process GO:0019218 2 0.046
positive regulation of signaling GO:0023056 243 0.046
positive regulation of cell communication GO:0010647 250 0.046
response to organonitrogen compound GO:0010243 75 0.046
carbohydrate derivative biosynthetic process GO:1901137 85 0.045
cellular protein localization GO:0034613 160 0.045
regulation of intracellular signal transduction GO:1902531 236 0.045
regulation of neurotransmitter levels GO:0001505 38 0.044
response to nutrient levels GO:0031667 114 0.044
regulation of cellular ketone metabolic process GO:0010565 3 0.044
defense response GO:0006952 300 0.044
Mouse
carboxylic acid metabolic process GO:0019752 92 0.044
mitotic nuclear division GO:0007067 213 0.044
cell motility GO:0048870 251 0.044
regulation of cell death GO:0010941 173 0.043
Human
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.043
dopamine biosynthetic process GO:0042416 3 0.043
regulation of phosphorus metabolic process GO:0051174 210 0.042
positive regulation of developmental process GO:0051094 143 0.042
regulation of heart rate GO:0002027 11 0.042
regulation of blood circulation GO:1903522 21 0.042
regulation of cellular protein metabolic process GO:0032268 243 0.042
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.042
Mouse
positive regulation of phosphate metabolic process GO:0045937 139 0.041
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.041
regulation of epithelial cell differentiation GO:0030856 4 0.041
Mouse
male gamete generation GO:0048232 201 0.041
Mouse
response to organic substance GO:0010033 284 0.041
regulation of nervous system development GO:0051960 248 0.041
positive regulation of protein metabolic process GO:0051247 128 0.041
pigmentation GO:0043473 75 0.041
mating behavior GO:0007617 106 0.040
regulation of chitin based cuticle tanning GO:0007564 14 0.040
cellular protein catabolic process GO:0044257 83 0.040
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 4 0.039
columnar cuboidal epithelial cell development GO:0002066 249 0.038
Mouse
organic acid metabolic process GO:0006082 103 0.038
tyrosine metabolic process GO:0006570 1 0.038
negative regulation of signaling GO:0023057 219 0.037
Mouse
macromolecule catabolic process GO:0009057 161 0.037
Mouse
cellular response to lipopolysaccharide GO:0071222 3 0.037
cell division GO:0051301 248 0.037
photoreceptor cell development GO:0042461 96 0.037
lipid metabolic process GO:0006629 121 0.037
regulation of transmembrane transporter activity GO:0022898 6 0.037
regulation of ion transport GO:0043269 39 0.037
regulation of system process GO:0044057 36 0.037
organophosphate metabolic process GO:0019637 195 0.037
dephosphorylation GO:0016311 51 0.037
aging GO:0007568 143 0.037
intracellular receptor signaling pathway GO:0030522 19 0.036
Mouse
response to organic cyclic compound GO:0014070 89 0.036
positive regulation of catalytic activity GO:0043085 118 0.036
regulation of membrane potential GO:0042391 35 0.036
protein targeting GO:0006605 64 0.036
posttranscriptional regulation of gene expression GO:0010608 145 0.036
negative regulation of purine nucleotide biosynthetic process GO:1900372 3 0.036
regionalization GO:0003002 416 0.035
nucleotide metabolic process GO:0009117 161 0.035
peptidyl threonine phosphorylation GO:0018107 2 0.035
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.035
Mouse
muscle organ development GO:0007517 127 0.035
response to inorganic substance GO:0010035 44 0.035
positive regulation of circadian sleep wake cycle sleep GO:0045938 8 0.035
cell aging GO:0007569 2 0.035
intracellular signal transduction GO:0035556 300 0.035
nucleoside phosphate metabolic process GO:0006753 162 0.035
negative regulation of sequestering of calcium ion GO:0051283 2 0.034
positive regulation of molecular function GO:0044093 136 0.034
Mouse
enteroendocrine cell differentiation GO:0035883 1 0.034
Mouse
intracellular protein transport GO:0006886 104 0.034
compound eye morphogenesis GO:0001745 249 0.034
regulation of hydrolase activity GO:0051336 97 0.033
cellular catabolic process GO:0044248 372 0.033
Mouse
organic hydroxy compound metabolic process GO:1901615 83 0.033
regulation of photoreceptor cell differentiation GO:0046532 34 0.033
response to external biotic stimulus GO:0043207 293 0.033
single organism membrane organization GO:0044802 93 0.033
developmental maturation GO:0021700 172 0.032
amine metabolic process GO:0009308 12 0.032
oxoacid metabolic process GO:0043436 103 0.032
positive regulation of cell death GO:0010942 69 0.032
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.032
regulation of catabolic process GO:0009894 170 0.032
regulation of adenylate cyclase activity GO:0045761 12 0.032
chemotaxis GO:0006935 249 0.032
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.032
regulation of cellular component biogenesis GO:0044087 201 0.031
respiratory system development GO:0060541 213 0.031
response to metal ion GO:0010038 23 0.031
regulation of peptide hormone secretion GO:0090276 5 0.031
Mouse
dendrite development GO:0016358 204 0.031
regulation of multi organism process GO:0043900 131 0.031
cation transmembrane transport GO:0098655 88 0.031
response to other organism GO:0051707 293 0.031
myotube cell development GO:0014904 3 0.031
chitin based cuticle sclerotization GO:0007593 19 0.031
phosphorylation GO:0016310 294 0.031
acid secretion GO:0046717 1 0.031
carboxylic acid transport GO:0046942 18 0.031
lateral inhibition GO:0046331 206 0.031
cell cycle phase transition GO:0044770 140 0.031
indole containing compound biosynthetic process GO:0042435 4 0.030
developmental growth GO:0048589 280 0.030
regulation of purine nucleotide biosynthetic process GO:1900371 14 0.030
regulation of ion transmembrane transport GO:0034765 27 0.030
regulation of transcription regulatory region dna binding GO:2000677 3 0.030
single organism nuclear import GO:1902593 51 0.030
divalent inorganic cation homeostasis GO:0072507 29 0.029
glial cell migration GO:0008347 31 0.029
regulation of programmed cell death GO:0043067 152 0.029
detection of visible light GO:0009584 38 0.029
retina development in camera type eye GO:0060041 4 0.029
negative regulation of multicellular organismal process GO:0051241 142 0.029
appendage morphogenesis GO:0035107 397 0.029
positive regulation of phosphorus metabolic process GO:0010562 139 0.029
negative regulation of molecular function GO:0044092 51 0.029
memory GO:0007613 94 0.029
cellular response to molecule of bacterial origin GO:0071219 3 0.029
cell migration GO:0016477 238 0.029
response to hypoxia GO:0001666 53 0.029
negative regulation of phosphorus metabolic process GO:0010563 45 0.028
organophosphate biosynthetic process GO:0090407 46 0.028
sensory perception of chemical stimulus GO:0007606 116 0.028
detection of chemical stimulus involved in sensory perception of taste GO:0050912 13 0.028
protein complex biogenesis GO:0070271 201 0.028
ribonucleotide metabolic process GO:0009259 145 0.028
immune system process GO:0002376 347 0.028
negative regulation of insulin secretion GO:0046676 1 0.028
single organism intracellular transport GO:1902582 207 0.028
cellular ion homeostasis GO:0006873 39 0.028
cell death GO:0008219 279 0.027
Human
negative regulation of camp metabolic process GO:0030815 3 0.027
protein complex assembly GO:0006461 200 0.027
neurotransmitter transport GO:0006836 37 0.027
anterior posterior axis specification embryo GO:0008595 103 0.027
regulation of cyclase activity GO:0031279 13 0.027
carbohydrate derivative metabolic process GO:1901135 217 0.027
response to hexose GO:0009746 3 0.026
positive regulation of cellular component biogenesis GO:0044089 80 0.026
regulation of rhodopsin mediated signaling pathway GO:0022400 17 0.026
positive regulation of camp metabolic process GO:0030816 8 0.026
skeletal muscle organ development GO:0060538 48 0.026
tube morphogenesis GO:0035239 191 0.026
cellular response to dna damage stimulus GO:0006974 223 0.026
Human
response to lipopolysaccharide GO:0032496 4 0.026
muscle structure development GO:0061061 224 0.026
anterior posterior axis specification GO:0009948 109 0.026
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.026
regulation of canonical wnt signaling pathway GO:0060828 15 0.026
long term memory GO:0007616 62 0.026
negative regulation of transcription regulatory region dna binding GO:2000678 3 0.026
response to biotic stimulus GO:0009607 294 0.026
response to oxygen containing compound GO:1901700 200 0.025
regulation of cytoplasmic transport GO:1903649 47 0.025
response to organophosphorus GO:0046683 2 0.025
cognition GO:0050890 141 0.025
immune response activating signal transduction GO:0002757 2 0.025
temperature homeostasis GO:0001659 2 0.025
axis specification GO:0009798 167 0.025
cellular response to abiotic stimulus GO:0071214 58 0.025
Human
nucleocytoplasmic transport GO:0006913 72 0.025
tripartite regional subdivision GO:0007351 103 0.025
enzyme linked receptor protein signaling pathway GO:0007167 179 0.025
macromolecular complex assembly GO:0065003 256 0.025
regulation of gene expression epigenetic GO:0040029 128 0.025
regulation of heart contraction GO:0008016 21 0.024
death GO:0016265 284 0.024
Human
cellular response to peptide hormone stimulus GO:0071375 28 0.024
positive regulation of cellular protein metabolic process GO:0032270 118 0.024
regulation of retinal cell programmed cell death GO:0046668 18 0.024
anterior posterior pattern specification GO:0009952 136 0.024
cellular response to nitrogen compound GO:1901699 51 0.024
regulation of immune system process GO:0002682 176 0.024
regulation of cell division GO:0051302 72 0.024
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 9 0.024
spermatogenesis GO:0007283 200 0.024
Mouse
cellular macromolecule catabolic process GO:0044265 136 0.024
Mouse
energy taxis GO:0009453 21 0.023
regulation of proteolysis GO:0030162 87 0.023
regulation of defense response GO:0031347 102 0.023
Mouse
tissue morphogenesis GO:0048729 297 0.023
detection of light stimulus involved in sensory perception GO:0050962 9 0.023
mating GO:0007618 120 0.023
phagocytosis GO:0006909 215 0.023
purine ribonucleotide biosynthetic process GO:0009152 28 0.023
forebrain development GO:0030900 2 0.023
intracellular steroid hormone receptor signaling pathway GO:0030518 12 0.023
Mouse
aromatic amino acid family metabolic process GO:0009072 3 0.023
optomotor response GO:0071632 3 0.023
cellular cation homeostasis GO:0030003 38 0.023
anion transport GO:0006820 41 0.023
mitotic cell cycle phase transition GO:0044772 138 0.023
positive regulation of calcium ion transport GO:0051928 4 0.023
detection of stimulus involved in sensory perception GO:0050906 92 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
oxidation reduction process GO:0055114 123 0.022
cyclic nucleotide metabolic process GO:0009187 28 0.022
nitrogen compound transport GO:0071705 85 0.022
Mouse
gene silencing by rna GO:0031047 57 0.022
olfactory learning GO:0008355 56 0.022
organonitrogen compound catabolic process GO:1901565 128 0.022
l amino acid import GO:0043092 2 0.022
negative regulation of cell differentiation GO:0045596 143 0.022
regulation of response to stress GO:0080134 200 0.022
Human Mouse
positive regulation of cellular component organization GO:0051130 156 0.022
appendage development GO:0048736 401 0.022
neuromuscular junction development GO:0007528 149 0.022
response to starvation GO:0042594 97 0.022
lipid localization GO:0010876 54 0.022
regulation of ion transmembrane transporter activity GO:0032412 6 0.022
organic anion transport GO:0015711 28 0.021
protein phosphorylation GO:0006468 169 0.021
positive regulation of cell cycle GO:0045787 43 0.021
immune response GO:0006955 246 0.021
catechol containing compound biosynthetic process GO:0009713 3 0.021
gene silencing GO:0016458 138 0.021
regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010578 8 0.021
response to endogenous stimulus GO:0009719 119 0.021
cellular response to biotic stimulus GO:0071216 4 0.021
glial cell differentiation GO:0010001 35 0.021
phototransduction visible light GO:0007603 27 0.021
myotube differentiation GO:0014902 46 0.021
multi organism behavior GO:0051705 175 0.021
molting cycle process GO:0022404 29 0.021
regulation of nucleotide biosynthetic process GO:0030808 14 0.021
metal ion homeostasis GO:0055065 44 0.020
protein kinase a signaling GO:0010737 2 0.020
rna processing GO:0006396 147 0.020
response to symbiotic bacterium GO:0009609 2 0.020
defense response to bacterium GO:0042742 178 0.020
serotonin metabolic process GO:0042428 2 0.020
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.020
regulation of synapse organization GO:0050807 110 0.020
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.020
response to glucose GO:0009749 2 0.020
regulation of vesicle mediated transport GO:0060627 59 0.020
regulation of developmental growth GO:0048638 174 0.020
positive regulation of catabolic process GO:0009896 105 0.020
anatomical structure homeostasis GO:0060249 97 0.019
nuclear transport GO:0051169 72 0.019
cation transport GO:0006812 110 0.019
immune response regulating signaling pathway GO:0002764 2 0.019
negative regulation of intracellular signal transduction GO:1902532 57 0.019
release of sequestered calcium ion into cytosol GO:0051209 1 0.019
cellular metal ion homeostasis GO:0006875 31 0.019
cellular amide metabolic process GO:0043603 80 0.019
wnt signaling pathway GO:0016055 98 0.019
dopamine metabolic process GO:0042417 7 0.019
innate immune response GO:0045087 144 0.019
neurotransmitter secretion GO:0007269 35 0.019
catecholamine biosynthetic process GO:0042423 3 0.019
regulation of muscle organ development GO:0048634 13 0.019
regulation of immune response GO:0050776 118 0.019
positive regulation of cell migration GO:0030335 2 0.019
olfactory behavior GO:0042048 97 0.019
embryonic pattern specification GO:0009880 174 0.019
protein import into nucleus translocation GO:0000060 6 0.018
growth GO:0040007 359 0.018
circadian regulation of gene expression GO:0032922 5 0.018
purine nucleotide biosynthetic process GO:0006164 29 0.018
regulation of cell differentiation GO:0045595 302 0.018
Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.018
regulation of cellular component movement GO:0051270 42 0.018
cytosolic calcium ion transport GO:0060401 2 0.018
regulation of purine nucleotide metabolic process GO:1900542 62 0.018
segmentation GO:0035282 207 0.018
negative regulation of cell proliferation GO:0008285 69 0.018
telencephalon development GO:0021537 2 0.018
peptidyl threonine modification GO:0018210 3 0.018
dna metabolic process GO:0006259 227 0.018
Human
positive regulation of developmental growth GO:0048639 62 0.018
catechol containing compound metabolic process GO:0009712 10 0.018
male courtship behavior veined wing generated song production GO:0045433 20 0.018
regulation of neurotransmitter secretion GO:0046928 14 0.017
regulation of developmental pigmentation GO:0048070 24 0.017
mrna processing GO:0006397 104 0.017
cellular response to carbohydrate stimulus GO:0071322 4 0.017
positive regulation of proteolysis GO:0045862 52 0.017
programmed cell death GO:0012501 257 0.017
positive regulation of protein catabolic process GO:0045732 34 0.017
dopamine receptor signaling pathway GO:0007212 4 0.017
translation GO:0006412 69 0.017
regulation of cellular response to insulin stimulus GO:1900076 17 0.017
feeding behavior GO:0007631 50 0.017
neuroblast proliferation GO:0007405 74 0.017
positive regulation of lyase activity GO:0051349 10 0.017
organonitrogen compound biosynthetic process GO:1901566 117 0.017
regulation of phosphorylation GO:0042325 147 0.017
synapse assembly GO:0007416 143 0.017
regulation of neurogenesis GO:0050767 158 0.017
cellular response to oxygen containing compound GO:1901701 79 0.017
cellular response to organic substance GO:0071310 132 0.017

Clk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.113
nervous system disease DOID:863 0 0.087
central nervous system disease DOID:331 0 0.020
neurodegenerative disease DOID:1289 0 0.020
cardiovascular system disease DOID:1287 0 0.020
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019