Drosophila melanogaster

72 known processes

CSN3 (Dmel_CG18332)

COP9 complex homolog subunit 3

(Aliases: Dch3,CH3,CG18332,Dmel\CG18332,Csn3,DCH3)

CSN3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein deneddylation GO:0000338 8 0.900
mitotic dna integrity checkpoint GO:0044774 75 0.882
mitotic g2 m transition checkpoint GO:0044818 70 0.856
g2 dna damage checkpoint GO:0031572 69 0.800
protein modification by small protein removal GO:0070646 28 0.737
mitotic dna damage checkpoint GO:0044773 74 0.730
negative regulation of cell cycle phase transition GO:1901988 103 0.686
mitotic cell cycle checkpoint GO:0007093 88 0.654
negative regulation of mitotic cell cycle GO:0045930 109 0.630
mitotic g2 dna damage checkpoint GO:0007095 69 0.559
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.551
negative regulation of cell cycle process GO:0010948 109 0.539
cellular protein modification process GO:0006464 438 0.498
regulation of mitotic cell cycle phase transition GO:1901990 130 0.476
regulation of cell cycle phase transition GO:1901987 130 0.457
negative regulation of cell cycle GO:0045786 116 0.444
cell cycle checkpoint GO:0000075 95 0.351
cullin deneddylation GO:0010388 3 0.350
Human
ubiquitin dependent protein catabolic process GO:0006511 78 0.313
Worm
lateral inhibition GO:0046331 206 0.296
dna damage checkpoint GO:0000077 78 0.258
regulation of mitotic cell cycle GO:0007346 190 0.257
regulation of cell cycle GO:0051726 291 0.257
dna integrity checkpoint GO:0031570 81 0.252
protein catabolic process GO:0030163 101 0.223
Worm
protein modification process GO:0036211 438 0.205
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.187
Worm
cellular response to dna damage stimulus GO:0006974 223 0.186
regulation of cell cycle process GO:0010564 181 0.149
positive regulation of macromolecule metabolic process GO:0010604 405 0.128
organic substance catabolic process GO:1901575 308 0.123
Worm
cell cycle phase transition GO:0044770 140 0.120
regulation of protein metabolic process GO:0051246 256 0.120
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.119
single organism nuclear import GO:1902593 51 0.109
cytokinesis GO:0000910 90 0.109
Worm
protein targeting to nucleus GO:0044744 51 0.108
regulation of defense response GO:0031347 102 0.102
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.102
protein modification by small protein conjugation or removal GO:0070647 106 0.096
regulation of cellular protein catabolic process GO:1903362 44 0.094
localization of cell GO:0051674 257 0.092
regionalization GO:0003002 416 0.090
protein localization to nucleus GO:0034504 55 0.083
mitotic cell cycle phase transition GO:0044772 138 0.080
modification dependent protein catabolic process GO:0019941 78 0.079
Worm
proteasomal protein catabolic process GO:0010498 59 0.079
positive regulation of gene expression GO:0010628 290 0.079
nuclear import GO:0051170 51 0.077
positive regulation of cell death GO:0010942 69 0.077
regulation of cellular protein metabolic process GO:0032268 243 0.075
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.074
regulation of protein stability GO:0031647 43 0.073
regulation of protein catabolic process GO:0042176 55 0.071
proteolysis GO:0006508 192 0.070
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.068
single organism cellular localization GO:1902580 180 0.066
Worm
cellular protein catabolic process GO:0044257 83 0.066
Worm
intracellular transport GO:0046907 228 0.065
regulation of cellular response to stress GO:0080135 89 0.063
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.062
regulation of response to stress GO:0080134 200 0.062
cellular response to chemical stimulus GO:0070887 199 0.061
regulation of protein transport GO:0051223 57 0.058
endomembrane system organization GO:0010256 119 0.057
positive regulation of response to stimulus GO:0048584 323 0.054
regulation of transport GO:0051049 181 0.053
regulation of localization GO:0032879 275 0.053
posttranscriptional regulation of gene expression GO:0010608 145 0.052
organic substance transport GO:0071702 257 0.052
vesicle mediated transport GO:0016192 381 0.052
dorsal ventral pattern formation GO:0009953 133 0.051
rna processing GO:0006396 147 0.051
cell cell signaling involved in cell fate commitment GO:0045168 210 0.049
negative regulation of cell proliferation GO:0008285 69 0.048
intracellular protein transport GO:0006886 104 0.047
regulation of cell proliferation GO:0042127 163 0.046
convergent extension GO:0060026 2 0.045
synaptic transmission GO:0007268 288 0.044
negative regulation of biosynthetic process GO:0009890 277 0.043
morphogenesis of an epithelium GO:0002009 276 0.043
embryo development ending in birth or egg hatching GO:0009792 152 0.041
Mouse
positive regulation of rna metabolic process GO:0051254 271 0.041
regulation of establishment of protein localization GO:0070201 61 0.039
modification dependent macromolecule catabolic process GO:0043632 79 0.039
Worm
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.036
regulation of response to external stimulus GO:0032101 115 0.036
cell motility GO:0048870 251 0.035
negative regulation of cellular metabolic process GO:0031324 382 0.035
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.035
cell migration GO:0016477 238 0.035
protein targeting GO:0006605 64 0.034
establishment of protein localization GO:0045184 163 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.033
regulation of intracellular protein transport GO:0033157 46 0.032
cellular macromolecule localization GO:0070727 220 0.031
genitalia development GO:0048806 26 0.031
protein import into nucleus GO:0006606 51 0.031
protein transport GO:0015031 155 0.030
cell division GO:0051301 248 0.029
Worm
nuclear transport GO:0051169 72 0.029
cell proliferation GO:0008283 299 0.028
positive regulation of cell communication GO:0010647 250 0.028
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.028
organonitrogen compound metabolic process GO:1901564 318 0.027
macromolecule catabolic process GO:0009057 161 0.027
Worm
negative regulation of cellular protein metabolic process GO:0032269 85 0.026
cell junction organization GO:0034330 57 0.026
protein localization GO:0008104 284 0.026
protein import GO:0017038 55 0.025
regulation of proteolysis GO:0030162 87 0.025
oocyte dorsal ventral axis specification GO:0007310 34 0.025
cell maturation GO:0048469 144 0.025
endocytosis GO:0006897 310 0.024
response to oxidative stress GO:0006979 86 0.024
positive regulation of cellular component biogenesis GO:0044089 80 0.024
membrane organization GO:0061024 112 0.023
regulation of nucleocytoplasmic transport GO:0046822 35 0.023
cellular catabolic process GO:0044248 372 0.023
Worm
chromatin modification GO:0016568 147 0.022
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.022
regulation of protein localization GO:0032880 76 0.022
positive regulation of cellular component organization GO:0051130 156 0.022
cellular macromolecule catabolic process GO:0044265 136 0.022
Worm
negative regulation of gene expression GO:0010629 387 0.022
response to radiation GO:0009314 155 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.021
negative regulation of transcription dna templated GO:0045892 237 0.021
regulation of cellular catabolic process GO:0031329 157 0.021
regulation of catabolic process GO:0009894 170 0.021
negative regulation of protein metabolic process GO:0051248 85 0.021
phosphorylation GO:0016310 294 0.021
eye photoreceptor cell differentiation GO:0001754 145 0.020
open tracheal system development GO:0007424 204 0.020
g protein coupled receptor signaling pathway GO:0007186 136 0.019
protein maturation GO:0051604 71 0.019
organelle localization GO:0051640 148 0.019
Worm
cell cell junction organization GO:0045216 55 0.019
negative regulation of proteolysis GO:0045861 31 0.019
epithelial structure maintenance GO:0010669 17 0.019
immune system development GO:0002520 57 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
positive regulation of signaling GO:0023056 243 0.017
regulation of protein import into nucleus GO:0042306 28 0.017
regulation of multicellular organismal development GO:2000026 414 0.017
reproductive behavior GO:0019098 122 0.017
single organism biosynthetic process GO:0044711 206 0.017
wing disc dorsal ventral pattern formation GO:0048190 47 0.016
protein modification by small protein conjugation GO:0032446 79 0.016
nucleus organization GO:0006997 45 0.016
protein ubiquitination GO:0016567 70 0.015
regulation of phosphorylation GO:0042325 147 0.015
maintenance of protein location GO:0045185 28 0.015
sex differentiation GO:0007548 81 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
negative regulation of catabolic process GO:0009895 36 0.015
negative regulation of signaling GO:0023057 219 0.015
purine containing compound catabolic process GO:0072523 112 0.015
negative regulation of cellular catabolic process GO:0031330 34 0.015
regulation of cytoplasmic transport GO:1903649 47 0.015
single organism intracellular transport GO:1902582 207 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
mrna processing GO:0006397 104 0.014
development of primary sexual characteristics GO:0045137 50 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
protein complex assembly GO:0006461 200 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.014
small molecule metabolic process GO:0044281 305 0.014
mrna polyadenylation GO:0006378 11 0.014
positive regulation of developmental process GO:0051094 143 0.014
neuromuscular synaptic transmission GO:0007274 67 0.014
imaginal disc derived appendage development GO:0048737 399 0.014
positive regulation of phosphorylation GO:0042327 87 0.014
regulation of neurogenesis GO:0050767 158 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
negative regulation of response to stimulus GO:0048585 258 0.013
blastoderm segmentation GO:0007350 159 0.013
embryonic morphogenesis GO:0048598 206 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
cellular protein localization GO:0034613 160 0.013
negative regulation of intracellular signal transduction GO:1902532 57 0.013
response to abiotic stimulus GO:0009628 341 0.013
regulation of translation GO:0006417 56 0.012
maintenance of location in cell GO:0051651 28 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
multi multicellular organism process GO:0044706 123 0.012
wing disc pattern formation GO:0035222 66 0.012
ncrna metabolic process GO:0034660 43 0.012
protein complex biogenesis GO:0070271 201 0.012
protein processing GO:0016485 68 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
reproductive structure development GO:0048608 74 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
protein polyubiquitination GO:0000209 11 0.012
positive regulation of signal transduction GO:0009967 223 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
nucleocytoplasmic transport GO:0006913 72 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
protein deubiquitination GO:0016579 17 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
ameboidal type cell migration GO:0001667 151 0.011
regulation of cell differentiation GO:0045595 302 0.011
regulation of protein processing GO:0070613 32 0.011
regulation of protein localization to nucleus GO:1900180 29 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
regulation of cell development GO:0060284 215 0.011
mapk cascade GO:0000165 107 0.011
single organism membrane organization GO:0044802 93 0.011
purine containing compound metabolic process GO:0072521 155 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.010
regulation of glial cell differentiation GO:0045685 1 0.010
protein k48 linked ubiquitination GO:0070936 3 0.010
central nervous system development GO:0007417 201 0.010
nuclear pore organization GO:0006999 1 0.010
morphogenesis of embryonic epithelium GO:0016331 94 0.010
male gamete generation GO:0048232 201 0.010

CSN3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019