Drosophila melanogaster

60 known processes

sub (Dmel_CG12298)

subito

(Aliases: mei-1794,SUB,CG12298,Dub,Dmel\CG12298,KIF20A)

sub biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle fission GO:0048285 340 0.969
meiotic chromosome segregation GO:0045132 59 0.964
meiotic cell cycle process GO:1903046 132 0.960
female meiotic division GO:0007143 70 0.933
nuclear division GO:0000280 332 0.918
meiosis i GO:0007127 59 0.914
Fly
meiotic nuclear division GO:0007126 151 0.900
chromosome segregation GO:0007059 157 0.750
organelle assembly GO:0070925 198 0.601
mitotic nuclear division GO:0007067 213 0.485
spindle assembly involved in meiosis GO:0090306 20 0.464
Fly
meiotic spindle organization GO:0000212 36 0.437
reciprocal meiotic recombination GO:0007131 19 0.410
meiotic cell cycle GO:0051321 171 0.400
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.369
spindle assembly involved in female meiosis GO:0007056 14 0.344
Fly
columnar cuboidal epithelial cell development GO:0002066 249 0.267
localization of cell GO:0051674 257 0.234
dna metabolic process GO:0006259 227 0.230
mitotic spindle organization GO:0007052 220 0.226
axis specification GO:0009798 167 0.211
dna recombination GO:0006310 32 0.192
epithelial cell development GO:0002064 274 0.185
embryonic pattern specification GO:0009880 174 0.184
male meiosis GO:0007140 52 0.179
cell division GO:0051301 248 0.171
chromosome organization GO:0051276 360 0.170
regulation of antimicrobial peptide production GO:0002784 44 0.163
female meiosis chromosome segregation GO:0016321 33 0.155
dorsal ventral pattern formation GO:0009953 133 0.151
epithelial cell differentiation GO:0030855 322 0.149
sister chromatid segregation GO:0000819 92 0.142
pronuclear migration GO:0035046 4 0.140
spindle assembly involved in mitosis GO:0090307 50 0.138
spindle assembly involved in female meiosis i GO:0007057 5 0.135
Fly
regulation of multi organism process GO:0043900 131 0.127
female meiosis i GO:0007144 8 0.121
Fly
protein complex biogenesis GO:0070271 201 0.119
body morphogenesis GO:0010171 2 0.114
regulation of cell cycle process GO:0010564 181 0.108
regionalization GO:0003002 416 0.100
meiotic sister chromatid segregation GO:0045144 6 0.100
regulation of humoral immune response GO:0002920 51 0.096
regulation of cellular amide metabolic process GO:0034248 39 0.095
organonitrogen compound biosynthetic process GO:1901566 117 0.092
spindle assembly GO:0051225 80 0.092
stem cell maintenance GO:0019827 67 0.086
mitotic sister chromatid segregation GO:0000070 87 0.086
protein complex assembly GO:0006461 200 0.085
positive regulation of response to stimulus GO:0048584 323 0.085
regulation of response to biotic stimulus GO:0002831 63 0.084
regulation of cell cycle GO:0051726 291 0.079
negative regulation of cell cycle GO:0045786 116 0.077
nucleobase containing compound catabolic process GO:0034655 165 0.077
spindle organization GO:0007051 253 0.076
meiosis ii GO:0007135 23 0.076
regulation of cell death GO:0010941 173 0.075
macromolecule catabolic process GO:0009057 161 0.074
cellular response to growth factor stimulus GO:0071363 30 0.073
aromatic compound catabolic process GO:0019439 166 0.073
ovarian follicle cell development GO:0030707 248 0.072
neuron projection guidance GO:0097485 241 0.072
establishment or maintenance of cell polarity GO:0007163 167 0.071
Fly
regulation of cell morphogenesis GO:0022604 163 0.070
neural precursor cell proliferation GO:0061351 75 0.070
maintenance of protein location in cell GO:0032507 26 0.066
oocyte differentiation GO:0009994 145 0.064
organic substance catabolic process GO:1901575 308 0.061
cell motility GO:0048870 251 0.057
regulation of production of molecular mediator of immune response GO:0002700 44 0.057
oocyte development GO:0048599 124 0.055
regulation of mitotic cell cycle GO:0007346 190 0.054
dorsal ventral axis specification GO:0009950 66 0.052
heterocycle catabolic process GO:0046700 166 0.052
forebrain development GO:0030900 2 0.052
actin filament organization GO:0007015 126 0.051
regulation of response to external stimulus GO:0032101 115 0.051
death GO:0016265 284 0.051
catabolic process GO:0009056 409 0.050
anterior posterior pattern specification GO:0009952 136 0.049
regulation of mitosis GO:0007088 56 0.049
antimicrobial humoral response GO:0019730 99 0.048
amide biosynthetic process GO:0043604 42 0.047
distributive segregation GO:0032837 6 0.046
Fly
organonitrogen compound metabolic process GO:1901564 318 0.046
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.046
cell cell signaling involved in cell fate commitment GO:0045168 210 0.046
establishment of organelle localization GO:0051656 122 0.044
Fly
organelle localization GO:0051640 148 0.044
Fly
blastoderm segmentation GO:0007350 159 0.044
oocyte maturation GO:0001556 3 0.044
stem cell proliferation GO:0072089 88 0.043
cellular component assembly involved in morphogenesis GO:0010927 151 0.043
immune effector process GO:0002252 98 0.042
negative regulation of cell cycle process GO:0010948 109 0.042
regulation of embryonic development GO:0045995 68 0.042
oocyte construction GO:0007308 112 0.042
response to biotic stimulus GO:0009607 294 0.041
negative regulation of epithelial cell proliferation GO:0050680 4 0.041
developmental maturation GO:0021700 172 0.041
humoral immune response GO:0006959 117 0.040
mitotic cell cycle embryonic GO:0045448 38 0.040
negative regulation of gene expression GO:0010629 387 0.039
single organism biosynthetic process GO:0044711 206 0.039
protein polymerization GO:0051258 42 0.039
Fly
oocyte axis specification GO:0007309 108 0.039
regulation of organelle organization GO:0033043 196 0.039
Fly
cell migration GO:0016477 238 0.038
neuroblast differentiation GO:0014016 29 0.038
positive regulation of catalytic activity GO:0043085 118 0.038
cellular nitrogen compound catabolic process GO:0044270 165 0.038
regulation of immune effector process GO:0002697 52 0.038
macromolecular complex assembly GO:0065003 256 0.038
peptide biosynthetic process GO:0043043 42 0.037
nuclear migration GO:0007097 20 0.037
cellular protein catabolic process GO:0044257 83 0.036
regulation of immune response GO:0050776 118 0.036
eggshell chorion assembly GO:0007306 66 0.035
reciprocal dna recombination GO:0035825 19 0.035
nucleus localization GO:0051647 34 0.035
dorsal appendage formation GO:0046843 47 0.035
immune response regulating signaling pathway GO:0002764 2 0.035
regulation of cell differentiation GO:0045595 302 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.034
cytoskeleton dependent cytokinesis GO:0061640 81 0.034
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.033
chemotaxis GO:0006935 249 0.033
cellular macromolecule catabolic process GO:0044265 136 0.033
response to organic substance GO:0010033 284 0.033
spinal cord development GO:0021510 1 0.031
microtubule polymerization or depolymerization GO:0031109 39 0.031
Fly
organic substance transport GO:0071702 257 0.031
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.031
vesicle mediated transport GO:0016192 381 0.030
actin cytoskeleton organization GO:0030036 206 0.030
programmed cell death GO:0012501 257 0.029
cellular catabolic process GO:0044248 372 0.029
chromatin modification GO:0016568 147 0.029
regulation of reproductive process GO:2000241 54 0.029
regulation of nuclear division GO:0051783 58 0.029
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.028
axonogenesis GO:0007409 290 0.028
cytokinesis GO:0000910 90 0.028
protein localization GO:0008104 284 0.028
regulation of phosphorus metabolic process GO:0051174 210 0.028
organic cyclic compound catabolic process GO:1901361 168 0.028
chromatin organization GO:0006325 207 0.028
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.028
positive regulation of wnt signaling pathway GO:0030177 25 0.028
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 8 0.028
cellular macromolecule localization GO:0070727 220 0.028
regulation of cellular response to growth factor stimulus GO:0090287 13 0.028
male meiosis chromosome segregation GO:0007060 10 0.027
embryonic axis specification GO:0000578 107 0.027
regulation of localization GO:0032879 275 0.027
regulation of cellular catabolic process GO:0031329 157 0.027
limb morphogenesis GO:0035108 1 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
regulation of antimicrobial humoral response GO:0002759 50 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.026
mitotic chromosome condensation GO:0007076 22 0.026
negative regulation of cell division GO:0051782 17 0.026
regulation of catalytic activity GO:0050790 185 0.026
stem cell division GO:0017145 69 0.026
intracellular signal transduction GO:0035556 300 0.026
sensory organ morphogenesis GO:0090596 260 0.026
peptide metabolic process GO:0006518 80 0.026
regulation of glial cell proliferation GO:0060251 11 0.026
segmentation GO:0035282 207 0.026
regulation of neurogenesis GO:0050767 158 0.026
anterior posterior axis specification GO:0009948 109 0.025
karyosome formation GO:0030717 22 0.025
crystal cell differentiation GO:0042688 7 0.025
negative regulation of developmental process GO:0051093 201 0.025
negative regulation of biosynthetic process GO:0009890 277 0.025
regulation of anatomical structure morphogenesis GO:0022603 242 0.025
positive regulation of rna metabolic process GO:0051254 271 0.024
compound eye morphogenesis GO:0001745 249 0.024
positive regulation of macromolecule metabolic process GO:0010604 405 0.024
spindle midzone assembly GO:0051255 4 0.024
positive regulation of cell communication GO:0010647 250 0.024
regulation of cell division GO:0051302 72 0.024
cellular protein modification process GO:0006464 438 0.024
glial cell proliferation GO:0014009 13 0.024
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.023
neuroblast fate determination GO:0007400 12 0.023
maintenance of location in cell GO:0051651 28 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.023
regulation of mitotic cell cycle embryonic GO:0009794 11 0.023
regulation of immune system process GO:0002682 176 0.023
asymmetric cell division GO:0008356 37 0.023
negative regulation of mitotic cell cycle GO:0045930 109 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
cell cycle phase transition GO:0044770 140 0.022
proteolysis GO:0006508 192 0.022
positive regulation of cellular component organization GO:0051130 156 0.022
Fly
regulation of catabolic process GO:0009894 170 0.022
ubiquitin dependent protein catabolic process GO:0006511 78 0.021
stem cell development GO:0048864 79 0.021
apoptotic process involved in morphogenesis GO:0060561 3 0.021
negative regulation of rna metabolic process GO:0051253 251 0.021
modification dependent protein catabolic process GO:0019941 78 0.021
positive regulation of signal transduction GO:0009967 223 0.021
single organism catabolic process GO:0044712 228 0.021
gland development GO:0048732 191 0.021
membrane organization GO:0061024 112 0.020
regulation of cell shape GO:0008360 113 0.020
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.020
dna repair GO:0006281 54 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
immune response GO:0006955 246 0.020
apoptotic process GO:0006915 159 0.020
regulation of cell development GO:0060284 215 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
spinal cord dorsal ventral patterning GO:0021513 1 0.020
hindbrain development GO:0030902 2 0.020
dna endoreduplication GO:0042023 22 0.019
developmental cell growth GO:0048588 52 0.019
negative regulation of programmed cell death GO:0043069 72 0.019
endocytosis GO:0006897 310 0.019
cell death GO:0008219 279 0.019
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.019
positive regulation of phosphorylation GO:0042327 87 0.019
positive regulation of signaling GO:0023056 243 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
eye morphogenesis GO:0048592 260 0.018
regulation of nervous system development GO:0051960 248 0.018
camera type eye development GO:0043010 4 0.018
chromosome condensation GO:0030261 41 0.018
mitotic spindle elongation GO:0000022 81 0.018
glycosyl compound catabolic process GO:1901658 112 0.018
regulation of epithelial cell proliferation GO:0050678 4 0.018
stem cell differentiation GO:0048863 117 0.018
small molecule metabolic process GO:0044281 305 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
antimicrobial peptide biosynthetic process GO:0002777 38 0.017
oocyte dorsal ventral axis specification GO:0007310 34 0.017
appendage development GO:0048736 401 0.017
regulation of cytoskeleton organization GO:0051493 89 0.017
Fly
regulation of locomotion GO:0040012 42 0.017
neuronal stem cell maintenance GO:0097150 4 0.017
positive regulation of molecular function GO:0044093 136 0.017
rho protein signal transduction GO:0007266 14 0.017
organelle fusion GO:0048284 46 0.017
regulation of neuron differentiation GO:0045664 103 0.017
regulation of protein metabolic process GO:0051246 256 0.017
eye photoreceptor cell differentiation GO:0001754 145 0.017
protein transport GO:0015031 155 0.017
notch signaling pathway GO:0007219 120 0.017
regulation of embryonic cell shape GO:0016476 30 0.016
cell cycle checkpoint GO:0000075 95 0.016
embryonic morphogenesis GO:0048598 206 0.016
purine containing compound catabolic process GO:0072523 112 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
response to other organism GO:0051707 293 0.016
immune response activating signal transduction GO:0002757 2 0.016
regulation of meiosis GO:0040020 3 0.016
sensory organ boundary specification GO:0008052 22 0.016
positive regulation of developmental process GO:0051094 143 0.016
chromosome organization involved in meiosis GO:0070192 10 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
single fertilization GO:0007338 24 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
limb development GO:0060173 1 0.015
establishment of localization in cell GO:0051649 402 0.015
Fly
eye development GO:0001654 323 0.015
regulation of microtubule cytoskeleton organization GO:0070507 41 0.015
Fly
imaginal disc derived appendage development GO:0048737 399 0.015
mapk cascade GO:0000165 107 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.015
ras protein signal transduction GO:0007265 88 0.015
eggshell formation GO:0030703 105 0.014
regulation of spindle elongation GO:0032887 1 0.014
regulation of notch signaling pathway GO:0008593 100 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
regulation of cellular component movement GO:0051270 42 0.014
cell maturation GO:0048469 144 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
telencephalon development GO:0021537 2 0.014
wing disc morphogenesis GO:0007472 344 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
axon development GO:0061564 297 0.014
compound eye development GO:0048749 307 0.014
cellular amide metabolic process GO:0043603 80 0.014
nephron morphogenesis GO:0072028 3 0.014
multicellular organismal aging GO:0010259 140 0.014
meiotic chromosome condensation GO:0010032 3 0.014
protein modification process GO:0036211 438 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.013
production of molecular mediator of immune response GO:0002440 46 0.013
gene silencing by rna GO:0031047 57 0.013
protein catabolic process GO:0030163 101 0.013
protein ubiquitination GO:0016567 70 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
regulation of cell proliferation GO:0042127 163 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
positive regulation of developmental growth GO:0048639 62 0.013
rna localization GO:0006403 115 0.013
positive regulation of nervous system development GO:0051962 69 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
immune system process GO:0002376 347 0.013
mitotic dna integrity checkpoint GO:0044774 75 0.013
organophosphate metabolic process GO:0019637 195 0.012
organophosphate catabolic process GO:0046434 112 0.012
negative regulation of organelle organization GO:0010639 56 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
negative regulation of cell death GO:0060548 81 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
negative regulation of cell proliferation GO:0008285 69 0.012
regulation of behavior GO:0050795 75 0.012
response to fibroblast growth factor GO:0071774 10 0.012
phosphorylation GO:0016310 294 0.012
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 4 0.012
regulation of axon extension involved in axon guidance GO:0048841 4 0.012
smoothened signaling pathway GO:0007224 49 0.012
positive regulation of cell migration GO:0030335 2 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
positive regulation of mapk cascade GO:0043410 63 0.012
neuroblast proliferation GO:0007405 74 0.012
regulation of stem cell proliferation GO:0072091 40 0.012
germ line stem cell division GO:0042078 25 0.012
maintenance of location GO:0051235 73 0.012
posttranscriptional gene silencing by rna GO:0035194 45 0.012
regulation of microtubule based process GO:0032886 49 0.012
Fly
sister chromatid cohesion GO:0007062 18 0.012
positive regulation of cell death GO:0010942 69 0.012
cellular protein complex disassembly GO:0043624 35 0.012
anterior posterior axis specification embryo GO:0008595 103 0.011
protein modification by small protein conjugation GO:0032446 79 0.011
negative regulation of cell cycle g2 m phase transition GO:1902750 8 0.011
developmental growth GO:0048589 280 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
regulation of programmed cell death GO:0043067 152 0.011
meiotic sister chromatid cohesion GO:0051177 6 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
regulation of heart morphogenesis GO:2000826 3 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
single organism intracellular transport GO:1902582 207 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
mitotic recombination GO:0006312 2 0.011
single organism membrane organization GO:0044802 93 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.011
response to external biotic stimulus GO:0043207 293 0.011
cell projection assembly GO:0030031 94 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
maintenance of protein location GO:0045185 28 0.011
germarium derived oocyte fate determination GO:0007294 26 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
locomotory behavior GO:0007626 176 0.011
rna 3 end processing GO:0031123 45 0.011
positive regulation of cell cycle GO:0045787 43 0.011
synaptic vesicle localization GO:0097479 53 0.010
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.010
courtship behavior GO:0007619 68 0.010
cellular response to chemical stimulus GO:0070887 199 0.010
post embryonic appendage morphogenesis GO:0035120 385 0.010
rna processing GO:0006396 147 0.010
neuron fate commitment GO:0048663 50 0.010
regulation of neural precursor cell proliferation GO:2000177 35 0.010
spindle assembly involved in male meiosis GO:0007053 5 0.010
mitotic dna damage checkpoint GO:0044773 74 0.010
regulation of mitotic spindle organization GO:0060236 9 0.010
nucleocytoplasmic transport GO:0006913 72 0.010
organic acid metabolic process GO:0006082 103 0.010
response to organic cyclic compound GO:0014070 89 0.010
mitotic centrosome separation GO:0007100 8 0.010
regulation of oocyte development GO:0060281 27 0.010
single organism cellular localization GO:1902580 180 0.010
Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.010
molting cycle chitin based cuticle GO:0007591 56 0.010

sub disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
central nervous system disease DOID:331 0 0.010
nervous system disease DOID:863 0 0.010
cardiovascular system disease DOID:1287 0 0.010