Drosophila melanogaster

94 known processes

pgc (Dmel_CG32885)

polar granule component

(Aliases: Pgc,Pgc1,CG11296,CR32885,CG32885,pgr,pgc-1,Dmel\CG32885)

pgc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
germ cell migration GO:0008354 43 0.185
development of primary sexual characteristics GO:0045137 50 0.076
chromosome organization GO:0051276 360 0.075
localization of cell GO:0051674 257 0.071
gonad development GO:0008406 50 0.061
response to temperature stimulus GO:0009266 106 0.059
rna splicing GO:0008380 83 0.057
g protein coupled receptor signaling pathway GO:0007186 136 0.057
single organism catabolic process GO:0044712 228 0.054
catabolic process GO:0009056 409 0.054
cell motility GO:0048870 251 0.053
rna localization GO:0006403 115 0.050
establishment of localization in cell GO:0051649 402 0.047
chromosome segregation GO:0007059 157 0.047
dna packaging GO:0006323 91 0.047
cell maturation GO:0048469 144 0.046
immune response GO:0006955 246 0.044
response to other organism GO:0051707 293 0.044
response to biotic stimulus GO:0009607 294 0.043
single organism behavior GO:0044708 391 0.042
cellular response to chemical stimulus GO:0070887 199 0.042
response to external biotic stimulus GO:0043207 293 0.041
response to abiotic stimulus GO:0009628 341 0.041
ribose phosphate metabolic process GO:0019693 145 0.041
organonitrogen compound metabolic process GO:1901564 318 0.041
death GO:0016265 284 0.041
neurological system process GO:0050877 358 0.040
regulation of cell cycle GO:0051726 291 0.038
defense response to bacterium GO:0042742 178 0.038
mrna processing GO:0006397 104 0.038
negative regulation of cellular metabolic process GO:0031324 382 0.037
defense response to other organism GO:0098542 225 0.036
cellular component assembly involved in morphogenesis GO:0010927 151 0.035
organic substance catabolic process GO:1901575 308 0.035
organelle fission GO:0048285 340 0.035
response to alcohol GO:0097305 95 0.035
response to bacterium GO:0009617 198 0.034
nuclear division GO:0000280 332 0.034
carboxylic acid metabolic process GO:0019752 92 0.034
response to organic substance GO:0010033 284 0.033
tripartite regional subdivision GO:0007351 103 0.033
aggressive behavior GO:0002118 63 0.033
response to nutrient levels GO:0031667 114 0.032
small molecule metabolic process GO:0044281 305 0.032
sex differentiation GO:0007548 81 0.031
sensory perception of chemical stimulus GO:0007606 116 0.031
programmed cell death GO:0012501 257 0.031
organelle assembly GO:0070925 198 0.031
spindle organization GO:0007051 253 0.031
cell migration GO:0016477 238 0.031
cellular catabolic process GO:0044248 372 0.031
oocyte differentiation GO:0009994 145 0.030
cell death GO:0008219 279 0.030
segmentation GO:0035282 207 0.030
chromatin organization GO:0006325 207 0.030
dna metabolic process GO:0006259 227 0.029
axis specification GO:0009798 167 0.029
negative regulation of gene expression GO:0010629 387 0.029
chromatin modification GO:0016568 147 0.029
embryonic pattern specification GO:0009880 174 0.029
anterior posterior axis specification embryo GO:0008595 103 0.028
aromatic compound catabolic process GO:0019439 166 0.028
camera type eye development GO:0043010 4 0.028
developmental programmed cell death GO:0010623 138 0.028
ribonucleotide metabolic process GO:0009259 145 0.028
defense response GO:0006952 300 0.027
telencephalon development GO:0021537 2 0.027
regulation of anatomical structure size GO:0090066 163 0.027
regulation of mitotic cell cycle phase transition GO:1901990 130 0.027
anterior posterior pattern specification GO:0009952 136 0.027
positive regulation of cellular biosynthetic process GO:0031328 316 0.027
regulation of cellular protein metabolic process GO:0032268 243 0.027
purine ribonucleotide metabolic process GO:0009150 145 0.027
response to monosaccharide GO:0034284 4 0.027
posttranscriptional regulation of gene expression GO:0010608 145 0.027
response to organophosphorus GO:0046683 2 0.027
response to mechanical stimulus GO:0009612 28 0.026
mitotic nuclear division GO:0007067 213 0.026
nucleoside phosphate metabolic process GO:0006753 162 0.026
regionalization GO:0003002 416 0.026
central nervous system development GO:0007417 201 0.026
regulation of protein metabolic process GO:0051246 256 0.025
pole plasm assembly GO:0007315 61 0.025
regulation of organelle organization GO:0033043 196 0.025
organic acid metabolic process GO:0006082 103 0.025
positive regulation of gene expression GO:0010628 290 0.025
synaptic transmission GO:0007268 288 0.024
purine nucleoside triphosphate metabolic process GO:0009144 119 0.024
response to endogenous stimulus GO:0009719 119 0.024
actin filament based process GO:0030029 220 0.024
mrna metabolic process GO:0016071 124 0.024
adult behavior GO:0030534 137 0.024
rna processing GO:0006396 147 0.024
sensory perception GO:0007600 196 0.024
protein localization GO:0008104 284 0.024
cellular nitrogen compound catabolic process GO:0044270 165 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.024
regulation of cellular catabolic process GO:0031329 157 0.023
oxoacid metabolic process GO:0043436 103 0.023
brain development GO:0007420 120 0.023
developmental growth GO:0048589 280 0.023
growth GO:0040007 359 0.023
transmembrane transport GO:0055085 139 0.023
cytoplasm organization GO:0007028 64 0.023
cellular response to oxygen containing compound GO:1901701 79 0.023
organic cyclic compound catabolic process GO:1901361 168 0.023
nucleobase containing compound catabolic process GO:0034655 165 0.022
mitotic spindle organization GO:0007052 220 0.022
positive regulation of multicellular organismal process GO:0051240 143 0.022
stem cell proliferation GO:0072089 88 0.022
organophosphate metabolic process GO:0019637 195 0.022
positive regulation of signaling GO:0023056 243 0.022
translation GO:0006412 69 0.022
mitotic sister chromatid segregation GO:0000070 87 0.022
negative regulation of cellular protein metabolic process GO:0032269 85 0.022
cellularization GO:0007349 90 0.022
chromatin remodeling GO:0006338 72 0.022
nucleotide metabolic process GO:0009117 161 0.022
positive regulation of macromolecule metabolic process GO:0010604 405 0.022
purine nucleotide metabolic process GO:0006163 146 0.022
oocyte anterior posterior axis specification GO:0007314 72 0.021
protein modification process GO:0036211 438 0.021
cell cycle phase transition GO:0044770 140 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.021
positive regulation of signal transduction GO:0009967 223 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.021
negative regulation of cell differentiation GO:0045596 143 0.021
anterior posterior axis specification GO:0009948 109 0.021
blastoderm segmentation GO:0007350 159 0.020
response to nitrogen compound GO:1901698 90 0.020
nucleoside phosphate catabolic process GO:1901292 110 0.020
developmental maturation GO:0021700 172 0.020
ribonucleoside triphosphate metabolic process GO:0009199 119 0.020
innate immune response GO:0045087 144 0.020
immune system process GO:0002376 347 0.020
oocyte construction GO:0007308 112 0.020
negative regulation of cell communication GO:0010648 223 0.020
heterocycle catabolic process GO:0046700 166 0.020
regulation of catalytic activity GO:0050790 185 0.019
positive regulation of cell communication GO:0010647 250 0.019
response to hexose GO:0009746 3 0.019
cell proliferation GO:0008283 299 0.019
cellular response to endogenous stimulus GO:0071495 80 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.019
establishment or maintenance of cell polarity GO:0007163 167 0.019
purine containing compound metabolic process GO:0072521 155 0.019
regulation of mitotic cell cycle GO:0007346 190 0.019
intracellular transport GO:0046907 228 0.019
carbohydrate derivative catabolic process GO:1901136 118 0.019
septate junction assembly GO:0019991 26 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
organonitrogen compound catabolic process GO:1901565 128 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
cellular macromolecule catabolic process GO:0044265 136 0.018
embryonic axis specification GO:0000578 107 0.018
defense response to gram negative bacterium GO:0050829 94 0.018
regulation of gene expression epigenetic GO:0040029 128 0.018
regulation of mitosis GO:0007088 56 0.018
regulation of meiosis GO:0040020 3 0.018
reproductive system development GO:0061458 74 0.018
regulation of proteasomal protein catabolic process GO:0061136 39 0.018
response to oxygen containing compound GO:1901700 200 0.017
somatic stem cell division GO:0048103 37 0.017
response to organonitrogen compound GO:0010243 75 0.017
pole plasm oskar mrna localization GO:0045451 46 0.017
benzene containing compound metabolic process GO:0042537 3 0.017
gene silencing GO:0016458 138 0.017
nucleobase containing small molecule metabolic process GO:0055086 174 0.017
negative regulation of translation GO:0017148 28 0.017
response to organic cyclic compound GO:0014070 89 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
sensory perception of smell GO:0007608 80 0.016
mechanosensory behavior GO:0007638 12 0.016
appendage morphogenesis GO:0035107 397 0.016
regulation of cell death GO:0010941 173 0.016
response to alkaloid GO:0043279 26 0.016
meiotic cell cycle GO:0051321 171 0.016
heterochromatin organization GO:0070828 25 0.016
intracellular signal transduction GO:0035556 300 0.016
microtubule organizing center organization GO:0031023 168 0.016
positive regulation of response to stimulus GO:0048584 323 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
multi organism behavior GO:0051705 175 0.016
cellular response to abiotic stimulus GO:0071214 58 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
head development GO:0060322 135 0.016
purine nucleoside triphosphate catabolic process GO:0009146 108 0.016
response to wounding GO:0009611 94 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
epithelial cell development GO:0002064 274 0.016
chaeta development GO:0022416 97 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
sensory perception of pain GO:0019233 4 0.015
regulation of mrna processing GO:0050684 71 0.015
macromolecule catabolic process GO:0009057 161 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
stem cell division GO:0017145 69 0.015
pole plasm rna localization GO:0007316 52 0.015
phagocytosis GO:0006909 215 0.015
cellular response to nitrogen compound GO:1901699 51 0.015
regulation of translation GO:0006417 56 0.015
regulation of nuclear division GO:0051783 58 0.015
neural precursor cell proliferation GO:0061351 75 0.015
body morphogenesis GO:0010171 2 0.015
oocyte development GO:0048599 124 0.015
neuroblast proliferation GO:0007405 74 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
ion transport GO:0006811 145 0.015
response to drug GO:0042493 17 0.015
negative regulation of rna metabolic process GO:0051253 251 0.015
response to extracellular stimulus GO:0009991 116 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
cellular response to biotic stimulus GO:0071216 4 0.015
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
purine nucleotide catabolic process GO:0006195 109 0.014
organophosphate catabolic process GO:0046434 112 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
purine ribonucleoside metabolic process GO:0046128 127 0.014
wound healing GO:0042060 75 0.014
pole plasm mrna localization GO:0019094 49 0.014
oocyte axis specification GO:0007309 108 0.014
meiotic nuclear division GO:0007126 151 0.014
nitrogen compound transport GO:0071705 85 0.014
response to trehalose GO:0010353 3 0.014
intracellular mrna localization GO:0008298 66 0.014
regulation of immune response GO:0050776 118 0.014
response to lipopolysaccharide GO:0032496 4 0.014
cellular protein modification process GO:0006464 438 0.014
proteolysis GO:0006508 192 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
cellular macromolecule localization GO:0070727 220 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
maternal determination of anterior posterior axis embryo GO:0008358 74 0.014
dna conformation change GO:0071103 105 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
regulation of cellular localization GO:0060341 136 0.014
regulation of response to stress GO:0080134 200 0.014
single organism biosynthetic process GO:0044711 206 0.014
cell projection assembly GO:0030031 94 0.014
sister chromatid segregation GO:0000819 92 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
spindle assembly GO:0051225 80 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
organic substance transport GO:0071702 257 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
modification dependent protein catabolic process GO:0019941 78 0.013
cell fate determination GO:0001709 91 0.013
regulation of embryonic development GO:0045995 68 0.013
rna splicing via transesterification reactions GO:0000375 73 0.013
regulation of mrna metabolic process GO:1903311 72 0.013
spermatogenesis GO:0007283 200 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.013
compound eye development GO:0048749 307 0.013
ubiquitin dependent protein catabolic process GO:0006511 78 0.013
regulation of transport GO:0051049 181 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.013
purine containing compound catabolic process GO:0072523 112 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
positive regulation of rna metabolic process GO:0051254 271 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
epithelial cell differentiation GO:0030855 322 0.012
regulation of localization GO:0032879 275 0.012
regulation of behavior GO:0050795 75 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
anion homeostasis GO:0055081 3 0.012
hindbrain development GO:0030902 2 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
establishment of rna localization GO:0051236 47 0.012
taxis GO:0042330 304 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
rna transport GO:0050658 46 0.012
response to inorganic substance GO:0010035 44 0.012
regulation of proteolysis GO:0030162 87 0.012
regulation of cell division GO:0051302 72 0.012
response to insecticide GO:0017085 14 0.012
compound eye morphogenesis GO:0001745 249 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
gene silencing by rna GO:0031047 57 0.012
modification dependent macromolecule catabolic process GO:0043632 79 0.012
forebrain development GO:0030900 2 0.012
cellular response to mechanical stimulus GO:0071260 2 0.012
cellular protein localization GO:0034613 160 0.011
tissue death GO:0016271 102 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
stem cell maintenance GO:0019827 67 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
steroid catabolic process GO:0006706 1 0.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.011
regulation of cell cycle process GO:0010564 181 0.011
mrna splicing via spliceosome GO:0000398 73 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
nucleoside catabolic process GO:0009164 112 0.011
nucleotide catabolic process GO:0009166 109 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
secretion GO:0046903 109 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
regulation of catabolic process GO:0009894 170 0.011
regulation of nucleotide metabolic process GO:0006140 62 0.011
chromosome condensation GO:0030261 41 0.011
sensory organ morphogenesis GO:0090596 260 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
organelle localization GO:0051640 148 0.011
response to hypoxia GO:0001666 53 0.011
tube morphogenesis GO:0035239 191 0.011
response to pain GO:0048265 3 0.011
negative regulation of organelle organization GO:0010639 56 0.011
stem cell differentiation GO:0048863 117 0.011
positive regulation of catabolic process GO:0009896 105 0.011
posttranscriptional gene silencing by rna GO:0035194 45 0.011
regulation of defense response GO:0031347 102 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
protein hydroxylation GO:0018126 1 0.011
protein catabolic process GO:0030163 101 0.010
limb development GO:0060173 1 0.010
positive regulation of molecular function GO:0044093 136 0.010
androgen metabolic process GO:0008209 1 0.010
regulation of cell differentiation GO:0045595 302 0.010
regulation of multi organism process GO:0043900 131 0.010
cellular response to organic cyclic compound GO:0071407 32 0.010
tissue migration GO:0090130 155 0.010
response to ketone GO:1901654 34 0.010

pgc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.055
hypertension DOID:10763 0 0.041
artery disease DOID:0050828 0 0.041
vascular disease DOID:178 0 0.041
essential hypertension DOID:10825 0 0.041
cardiovascular system disease DOID:1287 0 0.041
nervous system disease DOID:863 0 0.014
central nervous system disease DOID:331 0 0.010