Drosophila melanogaster

17 known processes

TepI (Dmel_CG18096)

Thiolester containing protein I

(Aliases: Dmel\CG18096,Tep-1,Tep1,BG:DS00365.2,dTEPI,tep1,CG18096,Tep I)

TepI biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response GO:0006952 300 0.212
defense response to other organism GO:0098542 225 0.152
response to external biotic stimulus GO:0043207 293 0.151
response to bacterium GO:0009617 198 0.132
response to other organism GO:0051707 293 0.118
immune system process GO:0002376 347 0.091
response to biotic stimulus GO:0009607 294 0.081
defense response to gram positive bacterium GO:0050830 41 0.073
Fly
sensory perception of chemical stimulus GO:0007606 116 0.066
defense response to bacterium GO:0042742 178 0.059
response to organic substance GO:0010033 284 0.046
cell proliferation GO:0008283 299 0.044
cellular protein modification process GO:0006464 438 0.042
taxis GO:0042330 304 0.040
protein modification process GO:0036211 438 0.037
organonitrogen compound metabolic process GO:1901564 318 0.037
xenobiotic catabolic process GO:0042178 1 0.037
regulation of immune system process GO:0002682 176 0.036
vesicle mediated transport GO:0016192 381 0.036
Fly
small molecule metabolic process GO:0044281 305 0.035
regulation of cell proliferation GO:0042127 163 0.035
response to lipopolysaccharide GO:0032496 4 0.034
immune response GO:0006955 246 0.034
hormone catabolic process GO:0042447 3 0.034
response to oxygen containing compound GO:1901700 200 0.034
cellular response to ethanol GO:0071361 4 0.031
body morphogenesis GO:0010171 2 0.031
appendage development GO:0048736 401 0.030
negative regulation of immune system process GO:0002683 50 0.030
cell cell signaling involved in cell fate commitment GO:0045168 210 0.030
steroid catabolic process GO:0006706 1 0.030
endocytosis GO:0006897 310 0.030
Fly
establishment of localization in cell GO:0051649 402 0.030
positive regulation of response to stimulus GO:0048584 323 0.029
catabolic process GO:0009056 409 0.029
oxoacid metabolic process GO:0043436 103 0.028
wing disc morphogenesis GO:0007472 344 0.028
regulation of multicellular organismal development GO:2000026 414 0.028
response to abiotic stimulus GO:0009628 341 0.028
organic acid metabolic process GO:0006082 103 0.028
positive regulation of cellular biosynthetic process GO:0031328 316 0.028
tube morphogenesis GO:0035239 191 0.028
neurological system process GO:0050877 358 0.028
sensory perception of smell GO:0007608 80 0.028
salivary gland development GO:0007431 162 0.027
estrogen metabolic process GO:0008210 1 0.027
response to paraquat GO:1901562 4 0.027
benzene containing compound metabolic process GO:0042537 3 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.027
organic substance catabolic process GO:1901575 308 0.027
carboxylic acid metabolic process GO:0019752 92 0.026
phagocytosis GO:0006909 215 0.026
Fly
imaginal disc derived appendage development GO:0048737 399 0.026
organic substance transport GO:0071702 257 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
sensory perception GO:0007600 196 0.025
appendage morphogenesis GO:0035107 397 0.025
secondary metabolic process GO:0019748 75 0.025
cell death GO:0008219 279 0.025
phosphorylation GO:0016310 294 0.025
exocrine system development GO:0035272 162 0.025
innate immune response GO:0045087 144 0.024
detection of stimulus GO:0051606 156 0.024
post embryonic appendage morphogenesis GO:0035120 385 0.024
imaginal disc derived appendage morphogenesis GO:0035114 395 0.024
negative regulation of cell proliferation GO:0008285 69 0.023
developmental programmed cell death GO:0010623 138 0.023
regionalization GO:0003002 416 0.023
chemotaxis GO:0006935 249 0.023
forebrain development GO:0030900 2 0.023
actin filament based process GO:0030029 220 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
camera type eye development GO:0043010 4 0.022
pigment metabolic process GO:0042440 84 0.022
cellular catabolic process GO:0044248 372 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
digestive tract development GO:0048565 149 0.022
lateral inhibition GO:0046331 206 0.022
single organism catabolic process GO:0044712 228 0.022
single organism behavior GO:0044708 391 0.022
gland morphogenesis GO:0022612 145 0.022
single organism biosynthetic process GO:0044711 206 0.022
death GO:0016265 284 0.022
tube development GO:0035295 244 0.022
digestive tract morphogenesis GO:0048546 127 0.021
response to nutrient levels GO:0031667 114 0.021
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
positive regulation of cell communication GO:0010647 250 0.021
response to radiation GO:0009314 155 0.021
detection of chemical stimulus GO:0009593 93 0.021
ion transport GO:0006811 145 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
intracellular signal transduction GO:0035556 300 0.021
compound eye development GO:0048749 307 0.021
transcription from rna polymerase ii promoter GO:0006366 368 0.020
androgen metabolic process GO:0008209 1 0.020
l amino acid import GO:0043092 2 0.020
eye development GO:0001654 323 0.020
cell motility GO:0048870 251 0.020
synaptic transmission GO:0007268 288 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
response to starvation GO:0042594 97 0.020
negative regulation of gene expression GO:0010629 387 0.020
digestive system development GO:0055123 149 0.020
response to extracellular stimulus GO:0009991 116 0.020
positive regulation of signaling GO:0023056 243 0.020
melanization defense response GO:0035006 45 0.020
multi organism behavior GO:0051705 175 0.020
salivary gland morphogenesis GO:0007435 145 0.020
gland development GO:0048732 191 0.020
lipid metabolic process GO:0006629 121 0.019
response to light stimulus GO:0009416 124 0.019
programmed cell death GO:0012501 257 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
localization of cell GO:0051674 257 0.019
aromatic compound catabolic process GO:0019439 166 0.019
response to alcohol GO:0097305 95 0.019
intracellular transport GO:0046907 228 0.019
g protein coupled receptor signaling pathway GO:0007186 136 0.019
regulation of localization GO:0032879 275 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
immune effector process GO:0002252 98 0.019
regulation of response to stress GO:0080134 200 0.019
organophosphate metabolic process GO:0019637 195 0.019
positive regulation of signal transduction GO:0009967 223 0.019
negative regulation of response to stimulus GO:0048585 258 0.019
cellular macromolecule localization GO:0070727 220 0.018
histolysis GO:0007559 102 0.018
axonogenesis GO:0007409 290 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
positive regulation of gene expression GO:0010628 290 0.018
l glutamate import GO:0051938 1 0.018
adult behavior GO:0030534 137 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
neuron projection guidance GO:0097485 241 0.018
organelle fission GO:0048285 340 0.018
cellular ketone metabolic process GO:0042180 24 0.018
melanin metabolic process GO:0006582 47 0.018
regulation of catalytic activity GO:0050790 185 0.018
transmembrane transport GO:0055085 139 0.018
negative regulation of cellular metabolic process GO:0031324 382 0.018
protein localization GO:0008104 284 0.017
response to ethanol GO:0045471 59 0.017
detection of chemical stimulus involved in sensory perception of smell GO:0050911 50 0.017
connective tissue development GO:0061448 3 0.017
single organism intracellular transport GO:1902582 207 0.017
proteolysis GO:0006508 192 0.017
response to temperature stimulus GO:0009266 106 0.017
activation of innate immune response GO:0002218 4 0.017
response to mercury ion GO:0046689 3 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
protein transport GO:0015031 155 0.017
cellular response to organic substance GO:0071310 132 0.017
response to endogenous stimulus GO:0009719 119 0.017
positive regulation of rna metabolic process GO:0051254 271 0.017
negative regulation of developmental process GO:0051093 201 0.017
cellular amine metabolic process GO:0044106 12 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
immune response activating signal transduction GO:0002757 2 0.017
regulation of transport GO:0051049 181 0.017
response to organophosphorus GO:0046683 2 0.017
developmental maturation GO:0021700 172 0.017
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.017
organonitrogen compound biosynthetic process GO:1901566 117 0.017
homeostatic process GO:0042592 199 0.016
regulation of molecular function GO:0065009 217 0.016
regulation of cell cycle GO:0051726 291 0.016
eye morphogenesis GO:0048592 260 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
carbohydrate metabolic process GO:0005975 82 0.016
dorsal ventral pattern formation GO:0009953 133 0.016
positive regulation of cell migration GO:0030335 2 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
immune response regulating signaling pathway GO:0002764 2 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
regulation of anatomical structure size GO:0090066 163 0.016
axon guidance GO:0007411 233 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
regulation of nervous system development GO:0051960 248 0.016
nucleotide metabolic process GO:0009117 161 0.016
developmental growth GO:0048589 280 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
amine metabolic process GO:0009308 12 0.016
salivary gland cell autophagic cell death GO:0035071 83 0.016
compound eye morphogenesis GO:0001745 249 0.016
telencephalon development GO:0021537 2 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
growth GO:0040007 359 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
epithelial cell differentiation GO:0030855 322 0.015
protein heterooligomerization GO:0051291 4 0.015
positive regulation of cell motility GO:2000147 3 0.015
macromolecule catabolic process GO:0009057 161 0.015
heterocycle catabolic process GO:0046700 166 0.015
response to organic cyclic compound GO:0014070 89 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
negative regulation of cell communication GO:0010648 223 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
tissue death GO:0016271 102 0.015
negative regulation of signaling GO:0023057 219 0.015
axis specification GO:0009798 167 0.015
regulation of multi organism process GO:0043900 131 0.015
cell maturation GO:0048469 144 0.015
antimicrobial humoral response GO:0019730 99 0.015
actin cytoskeleton organization GO:0030036 206 0.015
cell migration GO:0016477 238 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
tissue morphogenesis GO:0048729 297 0.015
oocyte differentiation GO:0009994 145 0.015
response to hexose GO:0009746 3 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
regulation of developmental growth GO:0048638 174 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
determination of adult lifespan GO:0008340 137 0.014
inter male aggressive behavior GO:0002121 60 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
macromolecular complex assembly GO:0065003 256 0.014
humoral immune response GO:0006959 117 0.014
ras protein signal transduction GO:0007265 88 0.014
protein phosphorylation GO:0006468 169 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
cell recognition GO:0008037 102 0.014
regulation of cell differentiation GO:0045595 302 0.014
organelle localization GO:0051640 148 0.014
response to heat GO:0009408 63 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
detection of stimulus involved in sensory perception GO:0050906 92 0.014
establishment of protein localization GO:0045184 163 0.014
respiratory system development GO:0060541 213 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
regulation of phosphorylation GO:0042325 147 0.014
phenol containing compound metabolic process GO:0018958 57 0.014
embryonic pattern specification GO:0009880 174 0.014
salivary gland histolysis GO:0035070 88 0.014
synapse organization GO:0050808 196 0.014
regulation of protein metabolic process GO:0051246 256 0.014
mating GO:0007618 120 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
cellular response to radiation GO:0071478 52 0.014
segmentation GO:0035282 207 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
protein hydroxylation GO:0018126 1 0.014
nuclear division GO:0000280 332 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
negative regulation of signal transduction GO:0009968 206 0.014
regulation of cell development GO:0060284 215 0.014
secretion GO:0046903 109 0.014
kidney development GO:0001822 3 0.014
establishment of organelle localization GO:0051656 122 0.014
regulation of cell death GO:0010941 173 0.013
ameboidal type cell migration GO:0001667 151 0.013
anion homeostasis GO:0055081 3 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
spindle organization GO:0007051 253 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
response to organonitrogen compound GO:0010243 75 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
axon development GO:0061564 297 0.013
purine containing compound metabolic process GO:0072521 155 0.013
multi multicellular organism process GO:0044706 123 0.013
retina development in camera type eye GO:0060041 4 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
response to nitrogen compound GO:1901698 90 0.013
regulation of response to external stimulus GO:0032101 115 0.013
sensory organ morphogenesis GO:0090596 260 0.013
detection of external stimulus GO:0009581 66 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
gastrulation GO:0007369 70 0.013
blastoderm segmentation GO:0007350 159 0.013
cellular protein localization GO:0034613 160 0.013
embryonic morphogenesis GO:0048598 206 0.013
neuropeptide signaling pathway GO:0007218 45 0.013
carbohydrate derivative biosynthetic process GO:1901137 85 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
cellular amide metabolic process GO:0043603 80 0.013
autophagic cell death GO:0048102 83 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
multicellular organismal aging GO:0010259 140 0.013
positive regulation of molecular function GO:0044093 136 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
nephron development GO:0072006 3 0.013
monocarboxylic acid transport GO:0015718 3 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
neuron recognition GO:0008038 101 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
regulation of defense response GO:0031347 102 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
Fly
detection of abiotic stimulus GO:0009582 66 0.013
phosphate ion transport GO:0006817 4 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
aging GO:0007568 143 0.013
mesenchymal cell differentiation GO:0048762 1 0.013
response to monosaccharide GO:0034284 4 0.012
positive regulation of immune system process GO:0002684 68 0.012
vitamin metabolic process GO:0006766 2 0.012
protein complex biogenesis GO:0070271 201 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
regulation of growth GO:0040008 233 0.012
open tracheal system development GO:0007424 204 0.012
innate immune response activating signal transduction GO:0002758 2 0.012
pattern recognition receptor signaling pathway GO:0002221 2 0.012
sterol homeostasis GO:0055092 4 0.012
regulation of mapk cascade GO:0043408 92 0.012
limb development GO:0060173 1 0.012
response to glucose GO:0009749 2 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
epithelial cell development GO:0002064 274 0.012
drinking behavior GO:0042756 2 0.012
behavioral response to ethanol GO:0048149 49 0.012
mapk cascade GO:0000165 107 0.012
gene silencing GO:0016458 138 0.012
mitotic nuclear division GO:0007067 213 0.012
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.012
single organism cellular localization GO:1902580 180 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
regulation of cell cycle process GO:0010564 181 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
leg disc development GO:0035218 92 0.012
endodermal cell differentiation GO:0035987 3 0.012
camera type eye morphogenesis GO:0048593 2 0.012
positive regulation of lipid storage GO:0010884 4 0.012
chemosensory behavior GO:0007635 106 0.012
rna processing GO:0006396 147 0.012
dorsal ventral axis specification GO:0009950 66 0.012
mating behavior GO:0007617 106 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
secretion by cell GO:0032940 101 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
ethanolamine containing compound metabolic process GO:0042439 4 0.012
sensory perception of pain GO:0019233 4 0.012
aggressive behavior GO:0002118 63 0.012
intracellular protein transmembrane transport GO:0065002 4 0.012
peptidyl proline hydroxylation GO:0019511 1 0.012
regulation of immune response GO:0050776 118 0.012
organelle assembly GO:0070925 198 0.012
cell division GO:0051301 248 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
regulation of cellular amide metabolic process GO:0034248 39 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
synaptic vesicle localization GO:0097479 53 0.012
regulation of humoral immune response GO:0002920 51 0.012
mrna metabolic process GO:0016071 124 0.012
fat soluble vitamin metabolic process GO:0006775 1 0.012
peptide metabolic process GO:0006518 80 0.012
ovarian follicle cell development GO:0030707 248 0.012
mesenchymal cell development GO:0014031 1 0.012
tissue migration GO:0090130 155 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
apoptotic process GO:0006915 159 0.011
imaginal disc pattern formation GO:0007447 91 0.011
nitrogen compound transport GO:0071705 85 0.011
actin filament based movement GO:0030048 26 0.011
chromosome organization GO:0051276 360 0.011
actin mediated cell contraction GO:0070252 21 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
regulation of innate immune response GO:0045088 71 0.011
regulation of hydrolase activity GO:0051336 97 0.011
vitamin biosynthetic process GO:0009110 1 0.011
mrna processing GO:0006397 104 0.011
cellular response to abiotic stimulus GO:0071214 58 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
protein transmembrane transport GO:0071806 4 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
ion transmembrane transport GO:0034220 122 0.011
protein maturation GO:0051604 71 0.011
reproductive behavior GO:0019098 122 0.011
regulation of programmed cell death GO:0043067 152 0.011
synaptic target recognition GO:0008039 45 0.011
establishment of synaptic vesicle localization GO:0097480 50 0.011
oocyte development GO:0048599 124 0.011
regulation of response to biotic stimulus GO:0002831 63 0.011
endomembrane system organization GO:0010256 119 0.011
response to copper ion GO:0046688 4 0.011
dendrite development GO:0016358 204 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
biological adhesion GO:0022610 138 0.011
antibacterial humoral response GO:0019731 44 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
regulation of organelle organization GO:0033043 196 0.011
positive regulation of immune response GO:0050778 63 0.011
actin filament organization GO:0007015 126 0.011
hindbrain development GO:0030902 2 0.011
positive regulation of developmental process GO:0051094 143 0.011
synapse assembly GO:0007416 143 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
intracellular protein transport GO:0006886 104 0.011
dendrite morphogenesis GO:0048813 199 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
amide biosynthetic process GO:0043604 42 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
wound healing GO:0042060 75 0.011
response to wounding GO:0009611 94 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
defense response to fungus GO:0050832 48 0.011
detection of light stimulus GO:0009583 58 0.010
cell adhesion GO:0007155 136 0.010
sensory perception of salty taste GO:0050914 3 0.010
fat soluble vitamin biosynthetic process GO:0042362 1 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
nucleoside metabolic process GO:0009116 127 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
spermatogenesis GO:0007283 200 0.010
g2 dna damage checkpoint GO:0031572 69 0.010
regulation of synapse organization GO:0050807 110 0.010
medium chain fatty acid metabolic process GO:0051791 1 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
regulation of apoptotic process GO:0042981 130 0.010
peptidyl amino acid modification GO:0018193 105 0.010
tripartite regional subdivision GO:0007351 103 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
kidney epithelium development GO:0072073 3 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010
positive regulation of catabolic process GO:0009896 105 0.010
rna localization GO:0006403 115 0.010
multi organism reproductive behavior GO:0044705 121 0.010
gene silencing by rna GO:0031047 57 0.010
negative regulation of cell cycle process GO:0010948 109 0.010
cation transport GO:0006812 110 0.010
translation GO:0006412 69 0.010
synaptic growth at neuromuscular junction GO:0051124 119 0.010
protein complex assembly GO:0006461 200 0.010
organic hydroxy compound metabolic process GO:1901615 83 0.010
synaptic vesicle transport GO:0048489 50 0.010

TepI disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.019
cardiovascular system disease DOID:1287 0 0.018
vascular disease DOID:178 0 0.013
disease of metabolism DOID:0014667 0 0.012
musculoskeletal system disease DOID:17 0 0.012
inherited metabolic disorder DOID:655 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
urinary system disease DOID:18 0 0.010
hypertension DOID:10763 0 0.010
artery disease DOID:0050828 0 0.010
central nervous system disease DOID:331 0 0.010