Drosophila melanogaster

127 known processes

so (Dmel_CG11121)

sine oculis

(Aliases: ami,med,old,mda,Drl,So,CG11121,SO,somda,Dmel\CG11121,Mdu)

so biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cell differentiation GO:0045596 143 0.995
Mouse
compound eye morphogenesis GO:0001745 249 0.988
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.986
compound eye development GO:0048749 307 0.982
sensory organ morphogenesis GO:0090596 260 0.977
compound eye photoreceptor cell differentiation GO:0001751 140 0.956
Fly
eye development GO:0001654 323 0.956
negative regulation of transcription dna templated GO:0045892 237 0.938
Mouse
gliogenesis GO:0042063 80 0.929
eye morphogenesis GO:0048592 260 0.927
glial cell migration GO:0008347 31 0.910
negative regulation of developmental process GO:0051093 201 0.908
Mouse
optic lobe placode formation GO:0001744 4 0.885
transcription from rna polymerase ii promoter GO:0006366 368 0.884
regulation of cell differentiation GO:0045595 302 0.863
Zebrafish Mouse
striated muscle cell differentiation GO:0051146 90 0.858
Zebrafish Fly
negative regulation of gene expression GO:0010629 387 0.848
Mouse
axonogenesis GO:0007409 290 0.837
circadian rhythm GO:0007623 105 0.832
axon guidance GO:0007411 233 0.826
dendrite development GO:0016358 204 0.807
Fly
axon development GO:0061564 297 0.766
stem cell differentiation GO:0048863 117 0.766
Mouse
camera type eye morphogenesis GO:0048593 2 0.752
protein localization GO:0008104 284 0.745
Human Mouse
cell death GO:0008219 279 0.737
Mouse
forebrain development GO:0030900 2 0.728
Zebrafish
neuron projection guidance GO:0097485 241 0.724
regulation of epithelial cell proliferation GO:0050678 4 0.717
Mouse
regulation of cell proliferation GO:0042127 163 0.708
Zebrafish Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.695
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 179 0.692
negative regulation of cell development GO:0010721 62 0.677
anterior posterior pattern specification GO:0009952 136 0.668
Mouse
photoreceptor cell fate commitment GO:0046552 41 0.666
positive regulation of cell proliferation GO:0008284 47 0.652
Mouse
tissue morphogenesis GO:0048729 297 0.632
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.615
Mouse
imaginal disc derived appendage development GO:0048737 399 0.614
cellular macromolecule localization GO:0070727 220 0.609
Human Mouse
regulation of heart morphogenesis GO:2000826 3 0.601
Mouse
kidney morphogenesis GO:0060993 3 0.578
Mouse
retina development in camera type eye GO:0060041 4 0.577
neural retina development GO:0003407 4 0.576
mesoderm development GO:0007498 78 0.557
Mouse Fly
taxis GO:0042330 304 0.556
regulation of anatomical structure morphogenesis GO:0022603 242 0.549
Mouse
positive regulation of rna metabolic process GO:0051254 271 0.509
imaginal disc derived wing morphogenesis GO:0007476 337 0.501
appendage morphogenesis GO:0035107 397 0.499
eye antennal disc development GO:0035214 60 0.499
imaginal disc derived appendage morphogenesis GO:0035114 395 0.491
ocellus development GO:0008056 4 0.488
camera type eye photoreceptor cell differentiation GO:0060219 2 0.483
embryonic organ development GO:0048568 50 0.481
Mouse
dendrite morphogenesis GO:0048813 199 0.473
Fly
organic substance transport GO:0071702 257 0.471
Mouse
respiratory system development GO:0060541 213 0.466
Mouse
establishment of localization in cell GO:0051649 402 0.464
Mouse
neuron fate commitment GO:0048663 50 0.459
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.450
Mouse
morphogenesis of an epithelium GO:0002009 276 0.446
Mouse
nephron morphogenesis GO:0072028 3 0.423
Mouse
wing disc morphogenesis GO:0007472 344 0.419
circulatory system development GO:0072359 82 0.406
Mouse
myotube differentiation GO:0014902 46 0.404
Zebrafish Fly
embryonic pattern specification GO:0009880 174 0.404
photoreceptor cell differentiation GO:0046530 170 0.404
Fly
endocrine system development GO:0035270 5 0.400
chromosome organization GO:0051276 360 0.398
positive regulation of macromolecule metabolic process GO:0010604 405 0.397
renal tubule development GO:0061326 64 0.395
Mouse
connective tissue development GO:0061448 3 0.394
Mouse Fly
post embryonic appendage morphogenesis GO:0035120 385 0.388
positive regulation of biosynthetic process GO:0009891 316 0.385
neuron fate specification GO:0048665 12 0.381
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.370
r7 cell differentiation GO:0045466 43 0.369
protein phosphorylation GO:0006468 169 0.368
regulation of nervous system development GO:0051960 248 0.364
Zebrafish Mouse
eye photoreceptor cell development GO:0042462 81 0.358
intracellular transport GO:0046907 228 0.352
Mouse
bolwig s organ development GO:0055034 8 0.344
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.324
Mouse
regulation of cell cycle phase transition GO:1901987 130 0.324
compound eye photoreceptor fate commitment GO:0001752 36 0.320
muscle organ development GO:0007517 127 0.310
Zebrafish Mouse
negative regulation of nervous system development GO:0051961 92 0.294
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.290
Mouse
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.290
regulation of cell death GO:0010941 173 0.289
Mouse
regulation of circadian rhythm GO:0042752 49 0.288
regulation of multicellular organismal development GO:2000026 414 0.284
Zebrafish Mouse
branching morphogenesis of an epithelial tube GO:0048754 45 0.283
Mouse
muscle structure development GO:0061061 224 0.279
Zebrafish Mouse Fly
genital disc development GO:0035215 44 0.278
embryonic morphogenesis GO:0048598 206 0.271
chemotaxis GO:0006935 249 0.269
eye photoreceptor cell fate commitment GO:0042706 37 0.268
morphogenesis of a branching structure GO:0001763 45 0.267
Mouse
stem cell development GO:0048864 79 0.263
Mouse
regulation of cell cycle GO:0051726 291 0.259
negative regulation of neurogenesis GO:0050768 53 0.258
cytoplasmic transport GO:0016482 130 0.258
Mouse
regulation of cell cycle process GO:0010564 181 0.254
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.249
positive regulation of transcription dna templated GO:0045893 266 0.247
cellular protein localization GO:0034613 160 0.239
Human Mouse
regulation of stem cell proliferation GO:0072091 40 0.236
Mouse
apoptotic signaling pathway GO:0097190 27 0.233
death GO:0016265 284 0.230
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.230
gland development GO:0048732 191 0.228
retina morphogenesis in camera type eye GO:0060042 2 0.228
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.227
cell cycle phase transition GO:0044770 140 0.225
programmed cell death GO:0012501 257 0.222
Mouse
eye photoreceptor cell differentiation GO:0001754 145 0.219
Fly
ectodermal placode morphogenesis GO:0071697 4 0.217
male gamete generation GO:0048232 201 0.216
kidney development GO:0001822 3 0.215
Human Zebrafish Mouse
anterior posterior axis specification GO:0009948 109 0.215
Mouse
protein transport GO:0015031 155 0.214
Mouse
head development GO:0060322 135 0.213
Zebrafish
establishment or maintenance of cell polarity GO:0007163 167 0.213
negative regulation of biosynthetic process GO:0009890 277 0.212
Mouse
regulation of protein metabolic process GO:0051246 256 0.208
appendage development GO:0048736 401 0.208
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.189
cardiovascular system development GO:0072358 82 0.188
Mouse
negative regulation of multicellular organismal process GO:0051241 142 0.188
Mouse
gland morphogenesis GO:0022612 145 0.179
negative regulation of epithelial cell proliferation GO:0050680 4 0.178
nephron tubule morphogenesis GO:0072078 3 0.177
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.175
Mouse
nephron development GO:0072006 3 0.174
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.173
Mouse
chromatin organization GO:0006325 207 0.171
nephron epithelium morphogenesis GO:0072088 3 0.169
Mouse
retinal cone cell differentiation GO:0042670 2 0.165
chorion containing eggshell formation GO:0007304 105 0.165
nucleocytoplasmic transport GO:0006913 72 0.162
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.160
Mouse
single organism behavior GO:0044708 391 0.159
regulation of organ morphogenesis GO:2000027 78 0.159
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.158
negative regulation of cellular protein metabolic process GO:0032269 85 0.155
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.153
amine metabolic process GO:0009308 12 0.150
epithelial tube morphogenesis GO:0060562 88 0.149
Mouse
camera type eye development GO:0043010 4 0.147
Zebrafish
cell type specific apoptotic process GO:0097285 38 0.146
Mouse
salivary gland morphogenesis GO:0007435 145 0.146
protein localization to nucleus GO:0034504 55 0.142
Human Mouse
defense response GO:0006952 300 0.142
optic lobe placode development GO:0001748 10 0.142
segmentation GO:0035282 207 0.139
positive regulation of multicellular organismal process GO:0051240 143 0.139
Mouse
formation of anatomical boundary GO:0048859 37 0.138
regulation of neuroblast proliferation GO:1902692 34 0.138
embryo development ending in birth or egg hatching GO:0009792 152 0.136
Mouse
gonad development GO:0008406 50 0.136
Fly
regulation of organ formation GO:0003156 3 0.133
Mouse
cell proliferation GO:0008283 299 0.130
Human Zebrafish Mouse
optic placode formation GO:0001743 4 0.128
response to wounding GO:0009611 94 0.126
imaginal disc growth GO:0007446 37 0.125
negative regulation of programmed cell death GO:0043069 72 0.122
Mouse
salivary gland development GO:0007431 162 0.122
hindbrain development GO:0030902 2 0.121
nuclear import GO:0051170 51 0.117
Mouse
secretion GO:0046903 109 0.116
kidney epithelium development GO:0072073 3 0.115
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.114
photoreceptor cell fate specification GO:0043704 9 0.112
regulation of cellular amino acid metabolic process GO:0006521 0 0.112
chromatin modification GO:0016568 147 0.109
exocrine system development GO:0035272 162 0.109
peptidyl threonine phosphorylation GO:0018107 2 0.107
negative regulation of cellular biosynthetic process GO:0031327 277 0.106
Mouse
regulation of neurogenesis GO:0050767 158 0.105
Zebrafish Mouse
open tracheal system development GO:0007424 204 0.105
regulation of mitotic cell cycle GO:0007346 190 0.104
brain development GO:0007420 120 0.104
Zebrafish
regulation of cell development GO:0060284 215 0.103
Zebrafish Mouse
syncytium formation GO:0006949 43 0.103
Fly
positive regulation of epithelial cell differentiation GO:0030858 1 0.102
wing disc pattern formation GO:0035222 66 0.100
negative regulation of molecular function GO:0044092 51 0.100
regulation of apoptotic signaling pathway GO:2001233 10 0.098
negative regulation of protein metabolic process GO:0051248 85 0.096
nephron epithelium development GO:0072009 3 0.095
Mouse
protein targeting GO:0006605 64 0.094
Mouse
renal system development GO:0072001 72 0.093
Human Zebrafish Mouse
response to abiotic stimulus GO:0009628 341 0.092
covalent chromatin modification GO:0016569 106 0.091
epithelial cell development GO:0002064 274 0.090
Mouse
single organism nuclear import GO:1902593 51 0.089
Mouse
heart morphogenesis GO:0003007 32 0.085
Mouse
telencephalon development GO:0021537 2 0.085
reproductive system development GO:0061458 74 0.084
Fly
enteroendocrine cell differentiation GO:0035883 1 0.083
response to fibroblast growth factor GO:0071774 10 0.083
positive regulation of cellular biosynthetic process GO:0031328 316 0.082
negative regulation of autophagy GO:0010507 16 0.081
photoreceptor cell axon guidance GO:0072499 23 0.080
regulation of organ growth GO:0046620 42 0.080
immune system development GO:0002520 57 0.079
Mouse
muscle cell differentiation GO:0042692 103 0.078
Zebrafish Mouse Fly
negative regulation of cell death GO:0060548 81 0.077
Mouse
dorsal ventral pattern formation GO:0009953 133 0.076
body morphogenesis GO:0010171 2 0.075
retinal cell programmed cell death GO:0046666 25 0.074
striated muscle tissue development GO:0014706 27 0.074
Zebrafish Mouse
response to growth factor GO:0070848 31 0.074
eggshell formation GO:0030703 105 0.073
urogenital system development GO:0001655 72 0.071
Human Zebrafish Mouse
reproductive structure development GO:0048608 74 0.071
Fly
nucleoside metabolic process GO:0009116 127 0.070
tube morphogenesis GO:0035239 191 0.070
Mouse
photoreceptor cell maintenance GO:0045494 11 0.069
negative regulation of catalytic activity GO:0043086 42 0.068
regulation of striated muscle tissue development GO:0016202 5 0.068
Mouse
regulation of localization GO:0032879 275 0.067
Mouse
larval development GO:0002164 104 0.067
organ formation GO:0048645 39 0.066
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 51 0.066
negative regulation of response to stimulus GO:0048585 258 0.066
intracellular protein transport GO:0006886 104 0.066
Mouse
nephron tubule development GO:0072080 3 0.066
Mouse
compound eye retinal cell programmed cell death GO:0046667 23 0.066
establishment of protein localization GO:0045184 163 0.065
Mouse
regulation of retinal cell programmed cell death GO:0046668 18 0.065
central nervous system development GO:0007417 201 0.063
Zebrafish Mouse
positive regulation of protein localization to nucleus GO:1900182 21 0.063
cell adhesion GO:0007155 136 0.063
bolwig s organ morphogenesis GO:0001746 8 0.063
regulation of cell division GO:0051302 72 0.062
embryonic axis specification GO:0000578 107 0.062
cellular protein modification process GO:0006464 438 0.062
eggshell chorion assembly GO:0007306 66 0.061
regulation of cell growth GO:0001558 43 0.061
morphogenesis of a branching epithelium GO:0061138 45 0.060
Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.060
dorsal appendage formation GO:0046843 47 0.060
positive regulation of cellular protein metabolic process GO:0032270 118 0.060
regulation of cellular protein metabolic process GO:0032268 243 0.060
regulation of programmed cell death GO:0043067 152 0.059
Mouse
ovarian follicle cell development GO:0030707 248 0.059
positive regulation of cell migration GO:0030335 2 0.058
blastoderm segmentation GO:0007350 159 0.057
hemopoiesis GO:0030097 46 0.056
cell fate specification GO:0001708 71 0.056
Mouse
renal tubule morphogenesis GO:0061333 44 0.055
Mouse
regulation of proteolysis GO:0030162 87 0.055
regulation of neuron differentiation GO:0045664 103 0.054
Zebrafish Mouse
regulation of secretion GO:0051046 44 0.054
compound eye cone cell differentiation GO:0042675 13 0.054
hematopoietic or lymphoid organ development GO:0048534 57 0.053
Mouse
response to radiation GO:0009314 155 0.053
regulation of mitotic cell cycle phase transition GO:1901990 130 0.053
regulation of cellular localization GO:0060341 136 0.053
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.053
cellular response to chemical stimulus GO:0070887 199 0.052
regulation of transport GO:0051049 181 0.052
imaginal disc pattern formation GO:0007447 91 0.051
regulation of insulin like growth factor receptor signaling pathway GO:0043567 3 0.051
regulation of cell motility GO:2000145 23 0.051
axis specification GO:0009798 167 0.051
Mouse
ectodermal placode formation GO:0060788 4 0.050
proteolysis GO:0006508 192 0.050
heart development GO:0007507 82 0.050
Mouse
regulation of cellular component biogenesis GO:0044087 201 0.049
Mouse
regulation of epithelial cell migration GO:0010632 12 0.049
organelle fission GO:0048285 340 0.049
development of primary sexual characteristics GO:0045137 50 0.049
Fly
spermatogenesis GO:0007283 200 0.048
protein modification by small protein conjugation GO:0032446 79 0.048
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.048
response to light stimulus GO:0009416 124 0.048
cell division GO:0051301 248 0.048
single organism cellular localization GO:1902580 180 0.047
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.047
neuron recognition GO:0008038 101 0.047
protein catabolic process GO:0030163 101 0.046
immune system process GO:0002376 347 0.046
Mouse
muscle tissue development GO:0060537 30 0.046
Zebrafish Mouse
anterior posterior axis specification embryo GO:0008595 103 0.046
regulation of growth GO:0040008 233 0.046
Mouse
regulation of endopeptidase activity GO:0052548 36 0.046
single organism membrane organization GO:0044802 93 0.046
protein localization to organelle GO:0033365 82 0.046
Human Mouse
establishment of planar polarity GO:0001736 87 0.046
signal release GO:0023061 49 0.046
secretion by cell GO:0032940 101 0.046
regulation of epithelial cell differentiation GO:0030856 4 0.045
regulation of protein deacetylation GO:0090311 2 0.045
establishment of tissue polarity GO:0007164 87 0.045
proximal distal pattern formation GO:0009954 15 0.044
response to alcohol GO:0097305 95 0.044
multicellular organismal aging GO:0010259 140 0.043
stem cell maintenance GO:0019827 67 0.042
Mouse
lipid localization GO:0010876 54 0.042
sex differentiation GO:0007548 81 0.042
Fly
positive regulation of synaptic transmission GO:0050806 15 0.042
histone modification GO:0016570 106 0.042
macromolecule catabolic process GO:0009057 161 0.041
epithelial cell differentiation GO:0030855 322 0.041
Mouse
compound eye photoreceptor development GO:0042051 78 0.041
protein import GO:0017038 55 0.040
Mouse
regulation of molecular function GO:0065009 217 0.040
notch signaling pathway GO:0007219 120 0.040
macromolecule deacylation GO:0098732 11 0.039
positive regulation of protein import into nucleus GO:0042307 21 0.039
anterior posterior pattern specification imaginal disc GO:0007448 16 0.039
protein modification process GO:0036211 438 0.039
negative regulation of wnt signaling pathway GO:0030178 28 0.038
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.038
mesenchymal cell development GO:0014031 1 0.038
outflow tract morphogenesis GO:0003151 4 0.038
Mouse
negative regulation of signaling GO:0023057 219 0.036
wnt signaling pathway GO:0016055 98 0.036
localization of cell GO:0051674 257 0.036
nuclear transport GO:0051169 72 0.036
Mouse
apoptotic process involved in development GO:1902742 20 0.036
cellular response to growth factor stimulus GO:0071363 30 0.035
positive regulation of cell cycle process GO:0090068 28 0.035
protein import into nucleus GO:0006606 51 0.035
Mouse
establishment of ommatidial planar polarity GO:0042067 49 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.034
Mouse
cellular component assembly involved in morphogenesis GO:0010927 151 0.034
entrainment of circadian clock GO:0009649 16 0.034
regulation of cellular component movement GO:0051270 42 0.034
digestive system development GO:0055123 149 0.034
Zebrafish Mouse
positive regulation of growth GO:0045927 75 0.034
mesenchyme development GO:0060485 9 0.034
Mouse
regulation of muscle organ development GO:0048634 13 0.034
Mouse
ventral cord development GO:0007419 16 0.034
glandular epithelial cell differentiation GO:0002067 1 0.034
cell motility GO:0048870 251 0.033
response to other organism GO:0051707 293 0.033
positive regulation of gene expression GO:0010628 290 0.033
single organism cell adhesion GO:0098602 47 0.033
regulation of cellular response to growth factor stimulus GO:0090287 13 0.033
digestive tract development GO:0048565 149 0.033
Zebrafish Mouse
regulation of protein localization GO:0032880 76 0.032
Mouse
glycosyl compound metabolic process GO:1901657 127 0.032
nitrogen compound transport GO:0071705 85 0.032
cell cell signaling involved in cell fate commitment GO:0045168 210 0.032
Mouse
cell junction organization GO:0034330 57 0.032
establishment of protein localization to organelle GO:0072594 62 0.031
Mouse
regulation of stem cell differentiation GO:2000736 14 0.031
histone deacetylation GO:0016575 9 0.031
regulation of muscle cell differentiation GO:0051147 8 0.031
organophosphate metabolic process GO:0019637 195 0.030
regulation of phosphate metabolic process GO:0019220 210 0.030
extrinsic apoptotic signaling pathway GO:0097191 1 0.030
male sex differentiation GO:0046661 25 0.030
equator specification GO:0045317 4 0.030
small molecule metabolic process GO:0044281 305 0.030
hematopoietic progenitor cell differentiation GO:0002244 1 0.029
developmental programmed cell death GO:0010623 138 0.029
organonitrogen compound metabolic process GO:1901564 318 0.029
embryonic organ morphogenesis GO:0048562 5 0.029
Mouse
muscle cell fate commitment GO:0042693 14 0.029
regulation of peptidase activity GO:0052547 39 0.028
somatic muscle development GO:0007525 66 0.028
negative regulation of signal transduction GO:0009968 206 0.028
peptidyl amino acid modification GO:0018193 105 0.028
nucleoside catabolic process GO:0009164 112 0.028
central complex development GO:0048036 9 0.028
imaginal disc derived leg segmentation GO:0036011 26 0.028
cellular macromolecular complex assembly GO:0034622 153 0.028
regulation of developmental growth GO:0048638 174 0.028
Mouse
purine nucleoside metabolic process GO:0042278 127 0.027
syncytium formation by plasma membrane fusion GO:0000768 43 0.027
Fly
positive regulation of protein metabolic process GO:0051247 128 0.027
organic substance catabolic process GO:1901575 308 0.027
gastrulation involving germ band extension GO:0010004 36 0.027
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.027
circadian behavior GO:0048512 76 0.027
nucleus localization GO:0051647 34 0.026
catabolic process GO:0009056 409 0.026
positive regulation of mitotic cell cycle GO:0045931 34 0.026
embryonic hemopoiesis GO:0035162 26 0.026
regulation of neural precursor cell proliferation GO:2000177 35 0.026
eye antennal disc morphogenesis GO:0007455 34 0.026
embryonic development via the syncytial blastoderm GO:0001700 148 0.026
regulation of cardioblast differentiation GO:0051890 9 0.026
lateral inhibition GO:0046331 206 0.026
ribonucleoside metabolic process GO:0009119 127 0.026
negative regulation of growth GO:0045926 84 0.025
purine nucleoside triphosphate metabolic process GO:0009144 119 0.025
positive regulation of signal transduction GO:0009967 223 0.025
cell cycle arrest GO:0007050 4 0.025
cell migration GO:0016477 238 0.025
peripheral nervous system development GO:0007422 52 0.025
Zebrafish
epidermis development GO:0008544 65 0.024
organelle localization GO:0051640 148 0.024
positive regulation of cellular catabolic process GO:0031331 95 0.024
atp metabolic process GO:0046034 49 0.024
apoptotic process GO:0006915 159 0.024
Mouse
positive regulation of developmental process GO:0051094 143 0.024
Mouse
negative regulation of neuron differentiation GO:0045665 16 0.023
limb development GO:0060173 1 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.023
regulation of protein modification process GO:0031399 112 0.023
cellular lipid metabolic process GO:0044255 83 0.023
response to lipopolysaccharide GO:0032496 4 0.023
growth GO:0040007 359 0.023
Mouse
glycosyl compound catabolic process GO:1901658 112 0.023
determination of adult lifespan GO:0008340 137 0.023
positive regulation of cell communication GO:0010647 250 0.023
developmental maturation GO:0021700 172 0.023
positive regulation of multicellular organism growth GO:0040018 21 0.022
response to transforming growth factor beta GO:0071559 18 0.022
leg disc development GO:0035218 92 0.022
dopamine biosynthetic process GO:0042416 3 0.022
protein targeting to nucleus GO:0044744 51 0.022
Mouse
leg disc proximal distal pattern formation GO:0007479 9 0.022
protein kinase b signaling GO:0043491 1 0.021
positive regulation of cell cycle GO:0045787 43 0.021
catechol containing compound biosynthetic process GO:0009713 3 0.021
positive regulation of stem cell proliferation GO:2000648 8 0.021
Mouse
cell recognition GO:0008037 102 0.020
neurotransmitter secretion GO:0007269 35 0.020
developmental induction GO:0031128 3 0.020
Mouse
purine containing compound metabolic process GO:0072521 155 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
mrna metabolic process GO:0016071 124 0.020
development of primary female sexual characteristics GO:0046545 12 0.020
cellular response to biotic stimulus GO:0071216 4 0.020
photoreceptor cell development GO:0042461 96 0.020
cellular response to abiotic stimulus GO:0071214 58 0.020
adult behavior GO:0030534 137 0.019
response to glucose GO:0009749 2 0.019
cell cell adhesion GO:0098609 26 0.019
negative regulation of hormone biosynthetic process GO:0032353 1 0.019
wound healing GO:0042060 75 0.019
rhythmic process GO:0048511 106 0.019
regulation of sequestering of calcium ion GO:0051282 3 0.019
peripheral nervous system neuron differentiation GO:0048934 8 0.019
Zebrafish
regulation of actin cytoskeleton organization GO:0032956 42 0.019
response to hypoxia GO:0001666 53 0.019
regulation of cysteine type endopeptidase activity GO:2000116 27 0.019
monocarboxylic acid transport GO:0015718 3 0.019
response to biotic stimulus GO:0009607 294 0.019
response to external biotic stimulus GO:0043207 293 0.019
synaptic growth at neuromuscular junction GO:0051124 119 0.019
Mouse
regulation of cell migration GO:0030334 22 0.018
ribonucleoside triphosphate metabolic process GO:0009199 119 0.018
axon target recognition GO:0007412 16 0.018
tube development GO:0035295 244 0.018
Zebrafish Mouse
regionalization GO:0003002 416 0.018
Mouse
cellular response to organic substance GO:0071310 132 0.018
mrna splicing via spliceosome GO:0000398 73 0.018
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.018
limb morphogenesis GO:0035108 1 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.017
response to oxygen containing compound GO:1901700 200 0.017
tripartite regional subdivision GO:0007351 103 0.017
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.017
response to hexose GO:0009746 3 0.017
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.017
histone acetylation GO:0016573 38 0.017
purine nucleotide catabolic process GO:0006195 109 0.017
gastrulation GO:0007369 70 0.017
Mouse
reactive oxygen species metabolic process GO:0072593 22 0.017
regulation of multi organism process GO:0043900 131 0.017
anterior commissure morphogenesis GO:0021960 2 0.017
bmp signaling pathway GO:0030509 27 0.017
establishment of rna localization GO:0051236 47 0.017
nucleotide metabolic process GO:0009117 161 0.017
multi organism reproductive behavior GO:0044705 121 0.017
establishment of spindle orientation GO:0051294 18 0.017
ameboidal type cell migration GO:0001667 151 0.017
establishment of cell polarity GO:0030010 40 0.017
apical constriction GO:0003383 18 0.017
nucleoside triphosphate catabolic process GO:0009143 108 0.016
cardioblast differentiation GO:0010002 20 0.016

so disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.846
Human
auditory system disease DOID:2742 0 0.368
Human
sensory system disease DOID:0050155 0 0.368
Human
nervous system disease DOID:863 0 0.368
Human
cancer DOID:162 0 0.277
disease of cellular proliferation DOID:14566 0 0.277
organ system cancer DOID:0050686 0 0.227
bone disease DOID:0080001 0 0.077
musculoskeletal system disease DOID:17 0 0.077
connective tissue disease DOID:65 0 0.077
physical disorder DOID:0080015 0 0.031
congenital nervous system abnormality DOID:2490 0 0.031
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.020
Human
nonsyndromic deafness DOID:0050563 0 0.020
Human
muscular disease DOID:0080000 0 0.016