Drosophila melanogaster

2 known processes

sPLA2 (Dmel_CG11124)

secretory Phospholipase A2

(Aliases: CG11124,Dmel\CG11124,CG14507,sPLA[[2]],secretory phospholipase A[[2]])

sPLA2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to bacterium GO:0009617 198 0.041
small molecule metabolic process GO:0044281 305 0.038
response to other organism GO:0051707 293 0.037
catabolic process GO:0009056 409 0.036
response to external biotic stimulus GO:0043207 293 0.036
organonitrogen compound metabolic process GO:1901564 318 0.035
cellular catabolic process GO:0044248 372 0.035
vesicle mediated transport GO:0016192 381 0.034
response to organic substance GO:0010033 284 0.033
response to biotic stimulus GO:0009607 294 0.032
organic substance catabolic process GO:1901575 308 0.032
response to abiotic stimulus GO:0009628 341 0.031
immune system process GO:0002376 347 0.031
death GO:0016265 284 0.030
endocytosis GO:0006897 310 0.029
protein modification process GO:0036211 438 0.028
negative regulation of gene expression GO:0010629 387 0.028
defense response GO:0006952 300 0.027
organic substance transport GO:0071702 257 0.027
positive regulation of response to stimulus GO:0048584 323 0.027
phagocytosis GO:0006909 215 0.027
appendage development GO:0048736 401 0.027
body morphogenesis GO:0010171 2 0.027
negative regulation of cellular metabolic process GO:0031324 382 0.026
single organism biosynthetic process GO:0044711 206 0.026
wing disc morphogenesis GO:0007472 344 0.026
imaginal disc derived appendage morphogenesis GO:0035114 395 0.025
gland development GO:0048732 191 0.025
cellular protein modification process GO:0006464 438 0.025
cell death GO:0008219 279 0.025
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
establishment of localization in cell GO:0051649 402 0.024
regulation of localization GO:0032879 275 0.024
response to lipopolysaccharide GO:0032496 4 0.024
compound eye development GO:0048749 307 0.024
appendage morphogenesis GO:0035107 397 0.024
single organism catabolic process GO:0044712 228 0.023
imaginal disc derived appendage development GO:0048737 399 0.023
salivary gland development GO:0007431 162 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
exocrine system development GO:0035272 162 0.023
defense response to other organism GO:0098542 225 0.023
organic acid metabolic process GO:0006082 103 0.022
response to oxygen containing compound GO:1901700 200 0.022
immune response GO:0006955 246 0.022
defense response to bacterium GO:0042742 178 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.022
regionalization GO:0003002 416 0.022
oxoacid metabolic process GO:0043436 103 0.022
organelle fission GO:0048285 340 0.022
positive regulation of cell communication GO:0010647 250 0.022
nuclear division GO:0000280 332 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
eye development GO:0001654 323 0.021
cellular response to chemical stimulus GO:0070887 199 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
programmed cell death GO:0012501 257 0.020
androgen metabolic process GO:0008209 1 0.020
organophosphate metabolic process GO:0019637 195 0.020
taxis GO:0042330 304 0.020
sensory organ morphogenesis GO:0090596 260 0.020
compound eye morphogenesis GO:0001745 249 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
proteolysis GO:0006508 192 0.020
regulation of multicellular organismal development GO:2000026 414 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
regulation of cell cycle GO:0051726 291 0.020
intracellular signal transduction GO:0035556 300 0.020
homeostatic process GO:0042592 199 0.019
single organism behavior GO:0044708 391 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.019
regulation of response to stress GO:0080134 200 0.019
salivary gland morphogenesis GO:0007435 145 0.019
positive regulation of signal transduction GO:0009967 223 0.019
macromolecule catabolic process GO:0009057 161 0.019
forebrain development GO:0030900 2 0.019
salivary gland cell autophagic cell death GO:0035071 83 0.019
gland morphogenesis GO:0022612 145 0.019
developmental programmed cell death GO:0010623 138 0.019
detection of stimulus GO:0051606 156 0.019
histolysis GO:0007559 102 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
pigment metabolic process GO:0042440 84 0.018
regulation of catalytic activity GO:0050790 185 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
response to radiation GO:0009314 155 0.018
kidney development GO:0001822 3 0.018
regulation of molecular function GO:0065009 217 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
spermatogenesis GO:0007283 200 0.018
phosphorylation GO:0016310 294 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
sterol homeostasis GO:0055092 4 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
positive regulation of signaling GO:0023056 243 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
negative regulation of biosynthetic process GO:0009890 277 0.017
protein localization GO:0008104 284 0.017
intracellular transport GO:0046907 228 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
eye morphogenesis GO:0048592 260 0.017
chromosome organization GO:0051276 360 0.017
neurological system process GO:0050877 358 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.017
aromatic compound catabolic process GO:0019439 166 0.017
lateral inhibition GO:0046331 206 0.017
xenobiotic catabolic process GO:0042178 1 0.017
negative regulation of signal transduction GO:0009968 206 0.016
response to nutrient levels GO:0031667 114 0.016
negative regulation of rna metabolic process GO:0051253 251 0.016
single organism intracellular transport GO:1902582 207 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
cell proliferation GO:0008283 299 0.016
camera type eye development GO:0043010 4 0.016
cellular macromolecule localization GO:0070727 220 0.016
regulation of immune system process GO:0002682 176 0.016
nucleotide metabolic process GO:0009117 161 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
innate immune response GO:0045087 144 0.016
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
regulation of transport GO:0051049 181 0.016
positive regulation of gene expression GO:0010628 290 0.016
spindle organization GO:0007051 253 0.016
heterocycle catabolic process GO:0046700 166 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.015
regulation of protein metabolic process GO:0051246 256 0.015
autophagic cell death GO:0048102 83 0.015
response to glucose GO:0009749 2 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
negative regulation of cell communication GO:0010648 223 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
lipid metabolic process GO:0006629 121 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
salivary gland histolysis GO:0035070 88 0.015
detection of chemical stimulus GO:0009593 93 0.015
negative regulation of signaling GO:0023057 219 0.015
response to monosaccharide GO:0034284 4 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
regulation of catabolic process GO:0009894 170 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
macromolecular complex assembly GO:0065003 256 0.014
cellular ketone metabolic process GO:0042180 24 0.014
regulation of cell death GO:0010941 173 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
cellular response to organic substance GO:0071310 132 0.014
male gamete generation GO:0048232 201 0.014
connective tissue development GO:0061448 3 0.014
response to hexose GO:0009746 3 0.014
negative regulation of developmental process GO:0051093 201 0.014
segmentation GO:0035282 207 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
steroid catabolic process GO:0006706 1 0.014
positive regulation of molecular function GO:0044093 136 0.014
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
telencephalon development GO:0021537 2 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
ras protein signal transduction GO:0007265 88 0.014
ion transport GO:0006811 145 0.014
growth GO:0040007 359 0.013
regulation of immune response GO:0050776 118 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
anion homeostasis GO:0055081 3 0.013
mitotic nuclear division GO:0007067 213 0.013
hormone catabolic process GO:0042447 3 0.013
cellular amine metabolic process GO:0044106 12 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
mitotic spindle organization GO:0007052 220 0.013
purine containing compound metabolic process GO:0072521 155 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
amine metabolic process GO:0009308 12 0.013
rna processing GO:0006396 147 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
cellular protein localization GO:0034613 160 0.013
regulation of cell differentiation GO:0045595 302 0.013
cell division GO:0051301 248 0.013
developmental growth GO:0048589 280 0.013
epithelial cell development GO:0002064 274 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
positive regulation of lipid storage GO:0010884 4 0.013
cholesterol homeostasis GO:0042632 3 0.013
positive regulation of cell migration GO:0030335 2 0.013
developmental maturation GO:0021700 172 0.013
cell cycle phase transition GO:0044770 140 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
cholesterol transport GO:0030301 2 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
response to temperature stimulus GO:0009266 106 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
tissue morphogenesis GO:0048729 297 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
immune response activating signal transduction GO:0002757 2 0.012
mating GO:0007618 120 0.012
positive regulation of catabolic process GO:0009896 105 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
carbohydrate metabolic process GO:0005975 82 0.012
positive regulation of cell motility GO:2000147 3 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
immune effector process GO:0002252 98 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
dna metabolic process GO:0006259 227 0.012
central nervous system development GO:0007417 201 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
ethanolamine containing compound metabolic process GO:0042439 4 0.012
gene silencing GO:0016458 138 0.012
regulation of cell cycle process GO:0010564 181 0.012
sensory perception GO:0007600 196 0.012
neutral lipid biosynthetic process GO:0046460 2 0.012
monocarboxylic acid transport GO:0015718 3 0.012
apoptotic process GO:0006915 159 0.012
protein transport GO:0015031 155 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
regulation of anatomical structure size GO:0090066 163 0.012
response to light stimulus GO:0009416 124 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
sensory perception of chemical stimulus GO:0007606 116 0.011
cell recognition GO:0008037 102 0.011
response to extracellular stimulus GO:0009991 116 0.011
regulation of organelle organization GO:0033043 196 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
response to alcohol GO:0097305 95 0.011
establishment of protein localization GO:0045184 163 0.011
maintenance of location GO:0051235 73 0.011
response to organophosphorus GO:0046683 2 0.011
response to endogenous stimulus GO:0009719 119 0.011
chromosome segregation GO:0007059 157 0.011
chemotaxis GO:0006935 249 0.011
adult behavior GO:0030534 137 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
rna localization GO:0006403 115 0.011
protein complex biogenesis GO:0070271 201 0.011
axon development GO:0061564 297 0.011
open tracheal system development GO:0007424 204 0.011
chromatin organization GO:0006325 207 0.011
secretion GO:0046903 109 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
response to organic cyclic compound GO:0014070 89 0.011
estrogen metabolic process GO:0008210 1 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.011
detection of abiotic stimulus GO:0009582 66 0.011
multi organism behavior GO:0051705 175 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
neuropeptide signaling pathway GO:0007218 45 0.011
benzene containing compound metabolic process GO:0042537 3 0.011
protein complex assembly GO:0006461 200 0.011
axon guidance GO:0007411 233 0.011
epithelial cell differentiation GO:0030855 322 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
axis specification GO:0009798 167 0.011
cytoplasmic transport GO:0016482 130 0.011
regulation of growth GO:0040008 233 0.011
developmental pigmentation GO:0048066 68 0.011
localization of cell GO:0051674 257 0.011
mrna metabolic process GO:0016071 124 0.011
tissue death GO:0016271 102 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
organophosphate catabolic process GO:0046434 112 0.011
antimicrobial humoral response GO:0019730 99 0.011
carbohydrate derivative biosynthetic process GO:1901137 85 0.011
cellular homeostasis GO:0019725 80 0.011
regulation of programmed cell death GO:0043067 152 0.011
microtubule organizing center organization GO:0031023 168 0.011
response to copper ion GO:0046688 4 0.011
regulation of defense response GO:0031347 102 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
peptide metabolic process GO:0006518 80 0.010
cation transport GO:0006812 110 0.010
regulation of nervous system development GO:0051960 248 0.010
embryonic pattern specification GO:0009880 174 0.010
response to nitrogen compound GO:1901698 90 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
vitamin metabolic process GO:0006766 2 0.010
meiotic cell cycle GO:0051321 171 0.010
transmembrane transport GO:0055085 139 0.010
locomotory behavior GO:0007626 176 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
humoral immune response GO:0006959 117 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
endomembrane system organization GO:0010256 119 0.010
retina development in camera type eye GO:0060041 4 0.010
protein phosphorylation GO:0006468 169 0.010
actin filament based process GO:0030029 220 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010
chaeta development GO:0022416 97 0.010
actin cytoskeleton organization GO:0030036 206 0.010
limb development GO:0060173 1 0.010
columnar cuboidal epithelial cell development GO:0002066 249 0.010
regulation of developmental growth GO:0048638 174 0.010
polyol biosynthetic process GO:0046173 3 0.010
intracellular protein transport GO:0006886 104 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010
embryonic development via the syncytial blastoderm GO:0001700 148 0.010
cell motility GO:0048870 251 0.010
regulation of innate immune response GO:0045088 71 0.010
respiratory system development GO:0060541 213 0.010
pigmentation GO:0043473 75 0.010
cell migration GO:0016477 238 0.010
regulation of cell cycle phase transition GO:1901987 130 0.010
blastoderm segmentation GO:0007350 159 0.010

sPLA2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.017
cardiovascular system disease DOID:1287 0 0.012
sensory system disease DOID:0050155 0 0.010
acquired metabolic disease DOID:0060158 0 0.010
musculoskeletal system disease DOID:17 0 0.010