Drosophila melanogaster

0 known processes

Reck (Dmel_CG5392)

Reversion-inducing-cysteine-rich protein with kazal motifs

(Aliases: RECK,Dmel\CG5392,CG5392)

Reck biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism behavior GO:0044708 391 0.163
muscle structure development GO:0061061 224 0.098
negative regulation of gene expression GO:0010629 387 0.089
eye development GO:0001654 323 0.084
sensory perception of chemical stimulus GO:0007606 116 0.077
neurological system process GO:0050877 358 0.068
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.062
appendage development GO:0048736 401 0.062
negative regulation of biosynthetic process GO:0009890 277 0.062
sensory perception GO:0007600 196 0.060
sensory organ morphogenesis GO:0090596 260 0.059
regionalization GO:0003002 416 0.059
cell recognition GO:0008037 102 0.054
segmentation GO:0035282 207 0.054
eye morphogenesis GO:0048592 260 0.053
taxis GO:0042330 304 0.053
regulation of cell differentiation GO:0045595 302 0.052
response to organic substance GO:0010033 284 0.052
positive regulation of nucleic acid templated transcription GO:1903508 266 0.052
appendage morphogenesis GO:0035107 397 0.051
positive regulation of rna metabolic process GO:0051254 271 0.051
regulation of multicellular organismal development GO:2000026 414 0.050
mesoderm development GO:0007498 78 0.049
neuron recognition GO:0008038 101 0.046
anterior posterior pattern specification GO:0009952 136 0.045
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.045
positive regulation of macromolecule metabolic process GO:0010604 405 0.045
axon development GO:0061564 297 0.044
small molecule metabolic process GO:0044281 305 0.043
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.042
compound eye development GO:0048749 307 0.042
camera type eye development GO:0043010 4 0.041
transcription from rna polymerase ii promoter GO:0006366 368 0.041
single organism biosynthetic process GO:0044711 206 0.041
imaginal disc derived appendage development GO:0048737 399 0.041
male mating behavior GO:0060179 70 0.041
negative regulation of transcription dna templated GO:0045892 237 0.041
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.041
negative regulation of cellular biosynthetic process GO:0031327 277 0.041
organonitrogen compound metabolic process GO:1901564 318 0.040
negative regulation of nucleic acid templated transcription GO:1903507 240 0.040
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.039
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.039
negative regulation of developmental process GO:0051093 201 0.038
blastoderm segmentation GO:0007350 159 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.038
chemotaxis GO:0006935 249 0.037
endocytosis GO:0006897 310 0.037
chromosome organization GO:0051276 360 0.037
embryonic pattern specification GO:0009880 174 0.037
cell motility GO:0048870 251 0.037
gland development GO:0048732 191 0.037
post embryonic appendage morphogenesis GO:0035120 385 0.036
cell death GO:0008219 279 0.035
negative regulation of signaling GO:0023057 219 0.035
positive regulation of response to stimulus GO:0048584 323 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.035
morphogenesis of an epithelium GO:0002009 276 0.035
positive regulation of rna biosynthetic process GO:1902680 266 0.035
muscle organ development GO:0007517 127 0.035
negative regulation of cellular metabolic process GO:0031324 382 0.035
cell proliferation GO:0008283 299 0.034
tube development GO:0035295 244 0.034
forebrain development GO:0030900 2 0.034
organelle fission GO:0048285 340 0.033
response to oxygen containing compound GO:1901700 200 0.033
regulation of cell death GO:0010941 173 0.033
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.033
compound eye morphogenesis GO:0001745 249 0.033
negative regulation of multicellular organismal process GO:0051241 142 0.033
neuron projection guidance GO:0097485 241 0.032
adult behavior GO:0030534 137 0.032
imaginal disc derived appendage morphogenesis GO:0035114 395 0.032
digestive tract development GO:0048565 149 0.032
cellular response to chemical stimulus GO:0070887 199 0.032
tube morphogenesis GO:0035239 191 0.032
exocrine system development GO:0035272 162 0.031
axonogenesis GO:0007409 290 0.031
nuclear division GO:0000280 332 0.031
localization of cell GO:0051674 257 0.031
tissue morphogenesis GO:0048729 297 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.030
regulation of cell cycle process GO:0010564 181 0.030
negative regulation of rna biosynthetic process GO:1902679 240 0.030
organic substance transport GO:0071702 257 0.030
positive regulation of signal transduction GO:0009967 223 0.029
developmental growth GO:0048589 280 0.029
connective tissue development GO:0061448 3 0.029
negative regulation of cell differentiation GO:0045596 143 0.029
gene silencing GO:0016458 138 0.029
regulation of programmed cell death GO:0043067 152 0.029
enzyme linked receptor protein signaling pathway GO:0007167 179 0.029
embryonic morphogenesis GO:0048598 206 0.029
formation of anatomical boundary GO:0048859 37 0.029
photoreceptor cell differentiation GO:0046530 170 0.029
axis specification GO:0009798 167 0.028
positive regulation of developmental process GO:0051094 143 0.028
regulation of cell cycle GO:0051726 291 0.028
cellular catabolic process GO:0044248 372 0.028
sensory perception of smell GO:0007608 80 0.028
axon guidance GO:0007411 233 0.028
death GO:0016265 284 0.028
positive regulation of transcription dna templated GO:0045893 266 0.027
cellular protein modification process GO:0006464 438 0.027
intracellular signal transduction GO:0035556 300 0.027
phagocytosis GO:0006909 215 0.027
negative regulation of signal transduction GO:0009968 206 0.027
positive regulation of signaling GO:0023056 243 0.027
dendrite morphogenesis GO:0048813 199 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
response to lipopolysaccharide GO:0032496 4 0.026
cell fate determination GO:0001709 91 0.026
salivary gland development GO:0007431 162 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
salt aversion GO:0035199 3 0.026
regulation of apoptotic process GO:0042981 130 0.026
positive regulation of gene expression GO:0010628 290 0.026
positive regulation of cell communication GO:0010647 250 0.026
positive regulation of cellular biosynthetic process GO:0031328 316 0.026
oxoacid metabolic process GO:0043436 103 0.026
anterior posterior axis specification GO:0009948 109 0.026
organophosphate metabolic process GO:0019637 195 0.025
androgen metabolic process GO:0008209 1 0.025
regulation of protein metabolic process GO:0051246 256 0.025
courtship behavior GO:0007619 68 0.025
body morphogenesis GO:0010171 2 0.025
synaptic target recognition GO:0008039 45 0.024
programmed cell death GO:0012501 257 0.024
vesicle mediated transport GO:0016192 381 0.024
nucleobase containing small molecule metabolic process GO:0055086 174 0.024
response to alcohol GO:0097305 95 0.024
negative regulation of rna metabolic process GO:0051253 251 0.024
carboxylic acid metabolic process GO:0019752 92 0.024
cell migration GO:0016477 238 0.024
digestive tract morphogenesis GO:0048546 127 0.024
store operated calcium entry GO:0002115 3 0.024
regulation of molecular function GO:0065009 217 0.024
catabolic process GO:0009056 409 0.024
dendrite development GO:0016358 204 0.023
regulation of gene expression epigenetic GO:0040029 128 0.023
growth GO:0040007 359 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
organic acid metabolic process GO:0006082 103 0.023
cellular response to organic substance GO:0071310 132 0.023
multi organism reproductive behavior GO:0044705 121 0.023
regulation of growth GO:0040008 233 0.023
cellular amino acid metabolic process GO:0006520 61 0.023
organic substance catabolic process GO:1901575 308 0.023
compound eye photoreceptor cell differentiation GO:0001751 140 0.023
malpighian tubule development GO:0072002 64 0.023
central nervous system development GO:0007417 201 0.022
organonitrogen compound biosynthetic process GO:1901566 117 0.022
actin cytoskeleton organization GO:0030036 206 0.022
head development GO:0060322 135 0.022
tripartite regional subdivision GO:0007351 103 0.022
apoptotic process GO:0006915 159 0.022
salivary gland morphogenesis GO:0007435 145 0.022
developmental maturation GO:0021700 172 0.022
detection of stimulus GO:0051606 156 0.022
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
kidney development GO:0001822 3 0.021
chemosensory behavior GO:0007635 106 0.021
organ formation GO:0048645 39 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
posttranscriptional regulation of gene expression GO:0010608 145 0.021
hormone catabolic process GO:0042447 3 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
embryonic development via the syncytial blastoderm GO:0001700 148 0.021
chromatin modification GO:0016568 147 0.020
locomotory behavior GO:0007626 176 0.020
immune system process GO:0002376 347 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.020
purine containing compound metabolic process GO:0072521 155 0.020
cation transport GO:0006812 110 0.020
eye photoreceptor cell differentiation GO:0001754 145 0.020
negative regulation of cell communication GO:0010648 223 0.020
ameboidal type cell migration GO:0001667 151 0.020
regulation of cell proliferation GO:0042127 163 0.020
protein modification process GO:0036211 438 0.020
regulation of localization GO:0032879 275 0.020
notch signaling pathway GO:0007219 120 0.020
respiratory system development GO:0060541 213 0.020
positive regulation of programmed cell death GO:0043068 62 0.019
mitotic nuclear division GO:0007067 213 0.019
pigmentation GO:0043473 75 0.019
proteolysis GO:0006508 192 0.019
response to abiotic stimulus GO:0009628 341 0.019
amine metabolic process GO:0009308 12 0.019
wing disc morphogenesis GO:0007472 344 0.019
olfactory behavior GO:0042048 97 0.019
regulation of developmental growth GO:0048638 174 0.019
gland morphogenesis GO:0022612 145 0.019
single organism catabolic process GO:0044712 228 0.019
cell adhesion GO:0007155 136 0.019
regulation of response to external stimulus GO:0032101 115 0.019
skeletal muscle organ development GO:0060538 48 0.019
telencephalon development GO:0021537 2 0.019
mating GO:0007618 120 0.019
brain development GO:0007420 120 0.018
cell division GO:0051301 248 0.018
heterocycle catabolic process GO:0046700 166 0.018
digestive system development GO:0055123 149 0.018
regulation of cell development GO:0060284 215 0.018
striated muscle cell differentiation GO:0051146 90 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.018
erbb signaling pathway GO:0038127 58 0.018
eye antennal disc development GO:0035214 60 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
ribose phosphate metabolic process GO:0019693 145 0.017
male gamete generation GO:0048232 201 0.017
formation of organ boundary GO:0010160 30 0.017
hindbrain development GO:0030902 2 0.017
macromolecule catabolic process GO:0009057 161 0.017
anatomical structure homeostasis GO:0060249 97 0.017
ribonucleotide metabolic process GO:0009259 145 0.017
endomembrane system organization GO:0010256 119 0.017
establishment of localization in cell GO:0051649 402 0.017
chaeta development GO:0022416 97 0.017
biological adhesion GO:0022610 138 0.016
multi organism behavior GO:0051705 175 0.016
protein localization GO:0008104 284 0.016
cellular ketone metabolic process GO:0042180 24 0.016
response to starvation GO:0042594 97 0.016
regulation of immune system process GO:0002682 176 0.016
regulation of catabolic process GO:0009894 170 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
positive regulation of cell death GO:0010942 69 0.016
peptidyl amino acid modification GO:0018193 105 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
spermatogenesis GO:0007283 200 0.016
multi multicellular organism process GO:0044706 123 0.016
epidermal growth factor receptor signaling pathway GO:0007173 58 0.016
hindgut morphogenesis GO:0007442 58 0.016
eye antennal disc morphogenesis GO:0007455 34 0.016
embryonic axis specification GO:0000578 107 0.016
mesenchymal cell differentiation GO:0048762 1 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
epithelial tube morphogenesis GO:0060562 88 0.016
response to endogenous stimulus GO:0009719 119 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
malpighian tubule morphogenesis GO:0007443 44 0.015
limb development GO:0060173 1 0.015
carbohydrate derivative biosynthetic process GO:1901137 85 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
cell maturation GO:0048469 144 0.015
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
epithelial cell differentiation GO:0030855 322 0.015
negative regulation of cell proliferation GO:0008285 69 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
positive regulation of cellular protein metabolic process GO:0032270 118 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
nucleotide metabolic process GO:0009117 161 0.015
covalent chromatin modification GO:0016569 106 0.015
stem cell proliferation GO:0072089 88 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
response to radiation GO:0009314 155 0.014
regulation of catalytic activity GO:0050790 185 0.014
sensory perception of sound GO:0007605 56 0.014
protein catabolic process GO:0030163 101 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
lateral inhibition GO:0046331 206 0.014
mesenchymal cell development GO:0014031 1 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
feeding behavior GO:0007631 50 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
phosphorylation GO:0016310 294 0.014
retina development in camera type eye GO:0060041 4 0.014
regulation of response to stress GO:0080134 200 0.014
cellular response to oxygen containing compound GO:1901701 79 0.014
sensory perception of salty taste GO:0050914 3 0.014
actin filament based process GO:0030029 220 0.014
secondary metabolic process GO:0019748 75 0.014
neuron fate commitment GO:0048663 50 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
ras protein signal transduction GO:0007265 88 0.014
camera type eye morphogenesis GO:0048593 2 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
hindgut development GO:0061525 58 0.014
aromatic compound catabolic process GO:0019439 166 0.014
spermatid development GO:0007286 98 0.014
negative regulation of gene expression epigenetic GO:0045814 77 0.014
developmental programmed cell death GO:0010623 138 0.013
positive regulation of cell motility GO:2000147 3 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.013
cell growth GO:0016049 108 0.013
mating behavior GO:0007617 106 0.013
benzene containing compound metabolic process GO:0042537 3 0.013
cellular amine metabolic process GO:0044106 12 0.013
regulation of gene silencing GO:0060968 63 0.013
reproductive behavior GO:0019098 122 0.013
negative regulation of nervous system development GO:0051961 92 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
smoothened signaling pathway GO:0007224 49 0.013
ion transport GO:0006811 145 0.013
lipid metabolic process GO:0006629 121 0.013
macromolecular complex assembly GO:0065003 256 0.013
sensory perception of taste GO:0050909 25 0.013
striated muscle cell development GO:0055002 50 0.012
leg disc development GO:0035218 92 0.012
negative regulation of growth GO:0045926 84 0.012
wound healing GO:0042060 75 0.012
positive regulation of molecular function GO:0044093 136 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
male courtship behavior GO:0008049 63 0.012
response to external biotic stimulus GO:0043207 293 0.012
spinal cord development GO:0021510 1 0.012
monocarboxylic acid transport GO:0015718 3 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
gastrulation GO:0007369 70 0.012
rhythmic behavior GO:0007622 76 0.012
nephron development GO:0072006 3 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
neural retina development GO:0003407 4 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
cellular lipid metabolic process GO:0044255 83 0.012
eye photoreceptor cell development GO:0042462 81 0.012
cell cycle phase transition GO:0044770 140 0.012
positive regulation of cell differentiation GO:0045597 64 0.012
histone modification GO:0016570 106 0.012
eye pigmentation GO:0048069 43 0.012
photoreceptor cell fate commitment GO:0046552 41 0.012
response to wounding GO:0009611 94 0.012
skeletal muscle fiber development GO:0048741 3 0.012
nephron epithelium development GO:0072009 3 0.012
cellular macromolecule localization GO:0070727 220 0.012
positive regulation of apoptotic process GO:0043065 47 0.012
embryonic organ development GO:0048568 50 0.012
segment specification GO:0007379 33 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
imaginal disc pattern formation GO:0007447 91 0.012
response to biotic stimulus GO:0009607 294 0.011
rna processing GO:0006396 147 0.011
glycerolipid metabolic process GO:0046486 34 0.011
secretion GO:0046903 109 0.011
chromatin organization GO:0006325 207 0.011
muscle cell differentiation GO:0042692 103 0.011
steroid catabolic process GO:0006706 1 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
protein phosphorylation GO:0006468 169 0.011
homeostatic process GO:0042592 199 0.011
photoreceptor cell development GO:0042461 96 0.011
pigment metabolic process GO:0042440 84 0.011
epithelial cell development GO:0002064 274 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
cellular response to ethanol GO:0071361 4 0.011
wnt signaling pathway GO:0016055 98 0.011
limb morphogenesis GO:0035108 1 0.011
kidney morphogenesis GO:0060993 3 0.011
renal tubule morphogenesis GO:0061333 44 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
defense response to bacterium GO:0042742 178 0.011
cell fate commitment involved in pattern specification GO:0060581 31 0.011
response to light stimulus GO:0009416 124 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.011
regulation of organelle organization GO:0033043 196 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
cytoplasmic transport GO:0016482 130 0.011
embryonic hindgut morphogenesis GO:0048619 48 0.011
positive regulation of cell migration GO:0030335 2 0.011
regulation of embryonic development GO:0045995 68 0.011
dna conformation change GO:0071103 105 0.011
renal tubule development GO:0061326 64 0.011
peripheral nervous system development GO:0007422 52 0.011
regulation of nervous system development GO:0051960 248 0.010
cellular response to dna damage stimulus GO:0006974 223 0.010
response to ethanol GO:0045471 59 0.010
protein complex assembly GO:0006461 200 0.010
detection of chemical stimulus GO:0009593 93 0.010
response to organophosphorus GO:0046683 2 0.010
establishment or maintenance of cell polarity GO:0007163 167 0.010
regulation of cell substrate adhesion GO:0010810 2 0.010
cell fate specification GO:0001708 71 0.010
cellular protein catabolic process GO:0044257 83 0.010
positive regulation of developmental growth GO:0048639 62 0.010
organophosphate biosynthetic process GO:0090407 46 0.010
regulation of wnt signaling pathway GO:0030111 68 0.010
positive regulation of growth GO:0045927 75 0.010
kidney epithelium development GO:0072073 3 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.010
organonitrogen compound catabolic process GO:1901565 128 0.010
circadian rhythm GO:0007623 105 0.010
negative regulation of cell death GO:0060548 81 0.010
cholesterol transport GO:0030301 2 0.010
convergent extension GO:0060026 2 0.010
adult locomotory behavior GO:0008344 76 0.010

Reck disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
disease of metabolism DOID:0014667 0 0.020
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.012
inherited metabolic disorder DOID:655 0 0.011