Drosophila melanogaster

0 known processes

CG5390 (Dmel_CG5390)

CG5390 gene product from transcript CG5390-RA

(Aliases: Dmel\CG5390,c-SPH35,gh06341,SPH35,BEST:GH06341)

CG5390 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response GO:0006952 300 0.486
Fly
response to biotic stimulus GO:0009607 294 0.412
Fly
defense response to gram positive bacterium GO:0050830 41 0.399
Fly
defense response to bacterium GO:0042742 178 0.334
Fly
positive regulation of melanization defense response GO:0035008 1 0.272
immune system process GO:0002376 347 0.249
Fly
immune response GO:0006955 246 0.204
sulfur compound metabolic process GO:0006790 59 0.170
regulation of immune response GO:0050776 118 0.159
aminoglycan metabolic process GO:0006022 18 0.156
regulation of immune system process GO:0002682 176 0.154
Fly
response to external biotic stimulus GO:0043207 293 0.132
Fly
response to fungus GO:0009620 50 0.125
humoral immune response GO:0006959 117 0.120
regulation of antimicrobial humoral response GO:0002759 50 0.119
vesicle mediated transport GO:0016192 381 0.116
detection of chemical stimulus GO:0009593 93 0.114
detection of molecule of fungal origin GO:0032491 1 0.105
endocytosis GO:0006897 310 0.103
peptide metabolic process GO:0006518 80 0.100
organonitrogen compound metabolic process GO:1901564 318 0.085
response to bacterium GO:0009617 198 0.083
Fly
antimicrobial humoral response GO:0019730 99 0.079
regulation of innate immune response GO:0045088 71 0.078
defense response to gram negative bacterium GO:0050829 94 0.075
positive regulation of response to stimulus GO:0048584 323 0.075
regulation of multi organism process GO:0043900 131 0.071
homeostatic process GO:0042592 199 0.069
hormone catabolic process GO:0042447 3 0.069
defense response to other organism GO:0098542 225 0.064
Fly
regulation of response to stress GO:0080134 200 0.063
extracellular structure organization GO:0043062 46 0.063
positive regulation of cell communication GO:0010647 250 0.063
activation of innate immune response GO:0002218 4 0.062
positive regulation of immune system process GO:0002684 68 0.060
Fly
chondroitin sulfate proteoglycan biosynthetic process GO:0050650 3 0.058
carbohydrate derivative metabolic process GO:1901135 217 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.054
proteoglycan metabolic process GO:0006029 10 0.054
detection of stimulus GO:0051606 156 0.053
response to other organism GO:0051707 293 0.051
Fly
organonitrogen compound biosynthetic process GO:1901566 117 0.050
positive regulation of signal transduction GO:0009967 223 0.049
organic acid metabolic process GO:0006082 103 0.046
regionalization GO:0003002 416 0.046
innate immune response GO:0045087 144 0.045
cellular amide metabolic process GO:0043603 80 0.045
axis specification GO:0009798 167 0.044
chondroitin sulfate biosynthetic process GO:0030206 2 0.042
establishment of localization in cell GO:0051649 402 0.040
regulation of hormone levels GO:0010817 40 0.040
catabolic process GO:0009056 409 0.039
salivary gland development GO:0007431 162 0.039
macromolecule catabolic process GO:0009057 161 0.038
organic substance catabolic process GO:1901575 308 0.037
regulation of response to external stimulus GO:0032101 115 0.037
small molecule metabolic process GO:0044281 305 0.036
regulation of cell proliferation GO:0042127 163 0.036
Fly
maintenance of location GO:0051235 73 0.036
extracellular matrix organization GO:0030198 32 0.035
phagocytosis GO:0006909 215 0.035
dorsal ventral pattern formation GO:0009953 133 0.035
cellular catabolic process GO:0044248 372 0.035
carboxylic acid metabolic process GO:0019752 92 0.034
detection of external biotic stimulus GO:0098581 2 0.034
determination of adult lifespan GO:0008340 137 0.033
regulation of cellular protein metabolic process GO:0032268 243 0.032
imaginal disc derived appendage development GO:0048737 399 0.032
carbohydrate derivative biosynthetic process GO:1901137 85 0.032
regulation of humoral immune response GO:0002920 51 0.032
positive regulation of immune response GO:0050778 63 0.032
response to oxygen containing compound GO:1901700 200 0.031
negative regulation of gene expression GO:0010629 387 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.029
regulation of immune effector process GO:0002697 52 0.028
dorsal ventral axis specification GO:0009950 66 0.028
regulation of toll signaling pathway GO:0008592 17 0.028
defense response to fungus GO:0050832 48 0.028
protein modification process GO:0036211 438 0.028
regulation of defense response GO:0031347 102 0.028
epithelial cell differentiation GO:0030855 322 0.027
appendage development GO:0048736 401 0.027
secretion by cell GO:0032940 101 0.026
positive regulation of signaling GO:0023056 243 0.026
cellular protein modification process GO:0006464 438 0.026
hormone metabolic process GO:0042445 33 0.026
response to radiation GO:0009314 155 0.025
chondroitin sulfate proteoglycan metabolic process GO:0050654 3 0.025
antibacterial peptide production GO:0002778 22 0.024
immune response regulating signaling pathway GO:0002764 2 0.024
response to endogenous stimulus GO:0009719 119 0.024
xenobiotic catabolic process GO:0042178 1 0.024
centrosome cycle GO:0007098 137 0.024
imaginal disc derived appendage morphogenesis GO:0035114 395 0.024
ion transport GO:0006811 145 0.023
positive regulation of defense response GO:0031349 59 0.023
wing disc morphogenesis GO:0007472 344 0.023
amino sugar metabolic process GO:0006040 10 0.023
regulation of protein metabolic process GO:0051246 256 0.022
peptidoglycan metabolic process GO:0000270 3 0.022
protein maturation GO:0051604 71 0.022
anatomical structure homeostasis GO:0060249 97 0.022
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
lipid metabolic process GO:0006629 121 0.021
negative regulation of cellular component organization GO:0051129 108 0.021
regulation of catalytic activity GO:0050790 185 0.020
pattern recognition receptor signaling pathway GO:0002221 2 0.020
neural precursor cell proliferation GO:0061351 75 0.020
phenol containing compound metabolic process GO:0018958 57 0.020
regulation of molecular function GO:0065009 217 0.020
response to monosaccharide GO:0034284 4 0.020
aminoglycan biosynthetic process GO:0006023 11 0.019
zymogen activation GO:0031638 20 0.019
connective tissue development GO:0061448 3 0.019
organonitrogen compound catabolic process GO:1901565 128 0.019
immune effector process GO:0002252 98 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
regulation of antimicrobial peptide production GO:0002784 44 0.018
androgen metabolic process GO:0008209 1 0.018
glycoprotein metabolic process GO:0009100 41 0.018
spindle organization GO:0007051 253 0.018
sulfur compound biosynthetic process GO:0044272 16 0.018
cell death GO:0008219 279 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
appendage morphogenesis GO:0035107 397 0.017
response to organic substance GO:0010033 284 0.017
oxoacid metabolic process GO:0043436 103 0.017
positive regulation of cellular amide metabolic process GO:0034250 26 0.017
exocrine system development GO:0035272 162 0.017
immune response activating signal transduction GO:0002757 2 0.017
tube development GO:0035295 244 0.016
glycosaminoglycan metabolic process GO:0030203 11 0.016
response to abiotic stimulus GO:0009628 341 0.016
regulation of proteolysis GO:0030162 87 0.016
body morphogenesis GO:0010171 2 0.015
macromolecular complex assembly GO:0065003 256 0.015
cell junction organization GO:0034330 57 0.015
negative regulation of homeostatic process GO:0032845 2 0.015
secretion GO:0046903 109 0.015
lateral inhibition GO:0046331 206 0.015
single organism biosynthetic process GO:0044711 206 0.015
gland development GO:0048732 191 0.015
response to glucose GO:0009749 2 0.014
single organism behavior GO:0044708 391 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.014
nuclear division GO:0000280 332 0.014
estrogen metabolic process GO:0008210 1 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
negative regulation of cell development GO:0010721 62 0.014
response to lipopolysaccharide GO:0032496 4 0.014
negative regulation of cell communication GO:0010648 223 0.014
developmental growth GO:0048589 280 0.013
response to organic cyclic compound GO:0014070 89 0.013
glycosaminoglycan catabolic process GO:0006027 3 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.013
melanization defense response GO:0035006 45 0.013
innate immune response activating signal transduction GO:0002758 2 0.013
gland morphogenesis GO:0022612 145 0.013
metal ion transport GO:0030001 74 0.013
neurotransmitter catabolic process GO:0042135 1 0.013
positive regulation of response to external stimulus GO:0032103 44 0.013
neuron recognition GO:0008038 101 0.013
regulation of nervous system development GO:0051960 248 0.013
chondroitin sulfate metabolic process GO:0030204 2 0.013
death GO:0016265 284 0.013
negative regulation of signaling GO:0023057 219 0.013
taxis GO:0042330 304 0.013
multicellular organismal aging GO:0010259 140 0.012
multicellular organismal homeostasis GO:0048871 41 0.012
autophagic cell death GO:0048102 83 0.012
cellular response to organic substance GO:0071310 132 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
biological adhesion GO:0022610 138 0.012
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.012
negative regulation of developmental process GO:0051093 201 0.012
epithelial cell development GO:0002064 274 0.012
regulation of production of molecular mediator of immune response GO:0002700 44 0.011
segmentation GO:0035282 207 0.011
detection of external stimulus GO:0009581 66 0.011
proteolysis GO:0006508 192 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
locomotory behavior GO:0007626 176 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
positive regulation of innate immune response GO:0045089 38 0.011
toll signaling pathway GO:0008063 25 0.011
compound eye development GO:0048749 307 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
regulation of neurogenesis GO:0050767 158 0.011
response to hexose GO:0009746 3 0.011
regulation of cell development GO:0060284 215 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.010
aging GO:0007568 143 0.010
neuroblast proliferation GO:0007405 74 0.010
programmed cell death GO:0012501 257 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
protein complex biogenesis GO:0070271 201 0.010
cell proliferation GO:0008283 299 0.010
Fly

CG5390 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.023
inherited metabolic disorder DOID:655 0 0.020
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.014