Drosophila melanogaster

353 known processes

sgg (Dmel_CG2621)

shaggy

(Aliases: sgg/zw3,EG:BACR7C10.8,ZW-3,l(1)zw3,anon-WO03040301.254,GSK3beta/SGG,DMSGG3,l(1)G0335,Gsk-3,GSK,Zw3,gsk3,sgg46,zw3/sgg,l(1)G0263,Zw-3,GSK3beta,EG:155E2.3,l(1)G0055,sgg10,CG2621,Zw3[sgg],l(1)3Ba,zw3(sgg),Zw3-sh,zw3,GSK3,SGG,Sgg/Zw3/GSK3,GSK-3,zw-3,GSK-3B,Dmel\CG2621,SGG/GSK3b,l(1)G0183,sgg39,zw3[sgg],sgg-zw3,zw3/GSK3beta,GSK-3beta,zw[3],GSKbeta,Dmsgg3,DMZ3K25Z,Zw3/GSK3,ZW3,Gsk3,Sgg,GSK3betagr)

sgg biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synapse assembly GO:0007416 143 0.999
regulation of growth GO:0040008 233 0.997
developmental growth GO:0048589 280 0.994
axonogenesis GO:0007409 290 0.993
Mouse
periodic partitioning GO:0007365 29 0.992
cell motility GO:0048870 251 0.990
Mouse Worm
axon guidance GO:0007411 233 0.988
positive regulation of macromolecule metabolic process GO:0010604 405 0.984
synapse organization GO:0050808 196 0.982
axon development GO:0061564 297 0.980
Mouse
taxis GO:0042330 304 0.977
establishment of localization in cell GO:0051649 402 0.977
Human Mouse Worm
learning or memory GO:0007611 141 0.974
developmental growth involved in morphogenesis GO:0060560 65 0.970
Mouse
growth GO:0040007 359 0.969
regionalization GO:0003002 416 0.966
synaptic growth at neuromuscular junction GO:0051124 119 0.965
neurological system process GO:0050877 358 0.946
actin filament based process GO:0030029 220 0.941
neuron projection guidance GO:0097485 241 0.935
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.926
Mouse
male gamete generation GO:0048232 201 0.909
Fly
branching morphogenesis of an epithelial tube GO:0048754 45 0.899
regulation of cytoskeleton organization GO:0051493 89 0.895
regulation of synapse assembly GO:0051963 94 0.895
spermatid differentiation GO:0048515 114 0.892
regulation of cell development GO:0060284 215 0.890
Mouse Rat
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.889
positive regulation of growth GO:0045927 75 0.886
Mouse
axis specification GO:0009798 167 0.886
mushroom body development GO:0016319 70 0.880
epithelial cell development GO:0002064 274 0.880
positive regulation of protein metabolic process GO:0051247 128 0.868
neuroblast proliferation GO:0007405 74 0.866
organelle localization GO:0051640 148 0.847
Worm
positive regulation of multicellular organismal process GO:0051240 143 0.836
Mouse
single organism behavior GO:0044708 391 0.830
regulation of nervous system development GO:0051960 248 0.820
embryonic pattern specification GO:0009880 174 0.816
establishment of organelle localization GO:0051656 122 0.793
Worm
hair cell differentiation GO:0035315 47 0.792
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.790
Human Mouse
wnt signaling pathway GO:0016055 98 0.789
Human Mouse Worm
negative regulation of response to stimulus GO:0048585 258 0.787
regulation of secretion by cell GO:1903530 39 0.786
response to temperature stimulus GO:0009266 106 0.779
organic substance transport GO:0071702 257 0.768
Human Mouse
respiratory system development GO:0060541 213 0.757
regulation of developmental growth GO:0048638 174 0.754
eye development GO:0001654 323 0.751
positive regulation of cell development GO:0010720 61 0.745
Mouse
positive regulation of nervous system development GO:0051962 69 0.740
Mouse
motor neuron axon guidance GO:0008045 58 0.736
spermatid development GO:0007286 98 0.721
regulation of transport GO:0051049 181 0.721
Human Mouse
locomotory behavior GO:0007626 176 0.716
compound eye development GO:0048749 307 0.716
compound eye morphogenesis GO:0001745 249 0.699
negative regulation of signal transduction GO:0009968 206 0.696
developmental maturation GO:0021700 172 0.687
Mouse
ribonucleoside metabolic process GO:0009119 127 0.686
Human
positive regulation of rna biosynthetic process GO:1902680 266 0.683
Mouse
regulation of synapse structure and activity GO:0050803 128 0.676
embryo development ending in birth or egg hatching GO:0009792 152 0.662
Worm
leg disc development GO:0035218 92 0.642
ion transport GO:0006811 145 0.639
neuromuscular junction development GO:0007528 149 0.627
intracellular signal transduction GO:0035556 300 0.627
morphogenesis of a branching epithelium GO:0061138 45 0.625
multi organism behavior GO:0051705 175 0.617
purine ribonucleoside catabolic process GO:0046130 112 0.607
Human
blastoderm segmentation GO:0007350 159 0.597
purine ribonucleoside metabolic process GO:0046128 127 0.596
Human
organonitrogen compound metabolic process GO:1901564 318 0.594
Human Mouse
epithelial cell differentiation GO:0030855 322 0.572
axon extension GO:0048675 32 0.572
Mouse
regulation of cell cycle GO:0051726 291 0.559
tube morphogenesis GO:0035239 191 0.555
nucleoside catabolic process GO:0009164 112 0.546
Human
positive regulation of rna metabolic process GO:0051254 271 0.543
Mouse
rhythmic behavior GO:0007622 76 0.542
membrane organization GO:0061024 112 0.542
Mouse Worm
head development GO:0060322 135 0.539
Human
chemotaxis GO:0006935 249 0.538
carbohydrate derivative catabolic process GO:1901136 118 0.538
Human
positive regulation of cell death GO:0010942 69 0.524
Mouse Rat
brain development GO:0007420 120 0.519
Human
dna metabolic process GO:0006259 227 0.518
Mouse
positive regulation of gene expression GO:0010628 290 0.507
Mouse
locomotor rhythm GO:0045475 56 0.505
cellular chemical homeostasis GO:0055082 40 0.505
localization of cell GO:0051674 257 0.484
Mouse Worm
imaginal disc derived wing hair organization GO:0035317 45 0.481
segment polarity determination GO:0007367 25 0.481
chromatin organization GO:0006325 207 0.477
organelle fission GO:0048285 340 0.467
secretion by cell GO:0032940 101 0.466
macromolecule catabolic process GO:0009057 161 0.464
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.460
nucleotide metabolic process GO:0009117 161 0.455
Human Mouse
sensory perception GO:0007600 196 0.453
nucleotide catabolic process GO:0009166 109 0.445
Human
response to radiation GO:0009314 155 0.433
spermatogenesis GO:0007283 200 0.423
stem cell proliferation GO:0072089 88 0.415
cell maturation GO:0048469 144 0.404
Mouse
skin development GO:0043588 65 0.404
purine nucleoside triphosphate metabolic process GO:0009144 119 0.401
Human
cognition GO:0050890 141 0.393
sensory organ morphogenesis GO:0090596 260 0.389
spindle organization GO:0007051 253 0.385
cell cycle phase transition GO:0044770 140 0.385
nucleoside metabolic process GO:0009116 127 0.381
Human
regulation of molecular function GO:0065009 217 0.380
purine ribonucleotide metabolic process GO:0009150 145 0.379
Human Mouse
cellular protein modification process GO:0006464 438 0.377
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.374
Human Mouse
imaginal disc derived appendage development GO:0048737 399 0.374
positive regulation of developmental growth GO:0048639 62 0.371
Mouse
imaginal disc derived wing morphogenesis GO:0007476 337 0.371
positive regulation of response to stimulus GO:0048584 323 0.369
Mouse
positive regulation of molecular function GO:0044093 136 0.367
Human Mouse
positive regulation of neuron differentiation GO:0045666 26 0.361
Mouse
germarium derived egg chamber formation GO:0007293 101 0.359
actin filament organization GO:0007015 126 0.358
circadian rhythm GO:0007623 105 0.355
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.341
Mouse
ribonucleoside catabolic process GO:0042454 112 0.336
Human
positive regulation of transcription dna templated GO:0045893 266 0.334
Mouse
nuclear division GO:0000280 332 0.328
imaginal disc pattern formation GO:0007447 91 0.327
purine ribonucleotide catabolic process GO:0009154 109 0.324
Human
regulation of anatomical structure size GO:0090066 163 0.323
Mouse
ribonucleotide catabolic process GO:0009261 109 0.319
Human
cell growth GO:0016049 108 0.317
Mouse
imaginal disc derived appendage morphogenesis GO:0035114 395 0.312
positive regulation of developmental process GO:0051094 143 0.311
Mouse
glycosyl compound metabolic process GO:1901657 127 0.310
Human
aromatic compound catabolic process GO:0019439 166 0.305
Human
protein complex biogenesis GO:0070271 201 0.303
Human
negative regulation of cell communication GO:0010648 223 0.299
asymmetric neuroblast division GO:0055059 33 0.299
embryonic morphogenesis GO:0048598 206 0.296
regulation of synaptic transmission GO:0050804 69 0.295
Rat
regulation of localization GO:0032879 275 0.295
Human Mouse Worm
oocyte differentiation GO:0009994 145 0.291
photoreceptor cell differentiation GO:0046530 170 0.290
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.286
regulation of cell morphogenesis GO:0022604 163 0.283
Mouse Rat
cell division GO:0051301 248 0.281
positive regulation of signal transduction GO:0009967 223 0.278
Mouse
tube development GO:0035295 244 0.277
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.276
regulation of multicellular organismal development GO:2000026 414 0.276
heterocycle catabolic process GO:0046700 166 0.270
Human
carbohydrate derivative metabolic process GO:1901135 217 0.267
Human Mouse
regulation of cellular component biogenesis GO:0044087 201 0.266
defense response GO:0006952 300 0.262
purine nucleoside monophosphate metabolic process GO:0009126 50 0.261
endoderm formation GO:0001706 3 0.253
modification dependent macromolecule catabolic process GO:0043632 79 0.252
morphogenesis of a branching structure GO:0001763 45 0.252
regulation of apoptotic process GO:0042981 130 0.251
Human Mouse Rat
regulation of phosphorus metabolic process GO:0051174 210 0.250
neuron recognition GO:0008038 101 0.249
immune effector process GO:0002252 98 0.247
secretion GO:0046903 109 0.244
epidermis development GO:0008544 65 0.243
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.240
cellular amino acid metabolic process GO:0006520 61 0.240
gastrulation GO:0007369 70 0.239
purine nucleoside metabolic process GO:0042278 127 0.231
Human
establishment or maintenance of cell polarity GO:0007163 167 0.227
positive regulation of cellular component organization GO:0051130 156 0.224
regulation of embryonic development GO:0045995 68 0.223
eye morphogenesis GO:0048592 260 0.212
neuron projection extension GO:1990138 32 0.212
Mouse
ras protein signal transduction GO:0007265 88 0.208
organ growth GO:0035265 56 0.203
Mouse
small molecule metabolic process GO:0044281 305 0.203
Human Mouse
germ cell migration GO:0008354 43 0.202
compound eye photoreceptor development GO:0042051 78 0.198
regulation of anatomical structure morphogenesis GO:0022603 242 0.197
Mouse Rat
regulation of protein modification process GO:0031399 112 0.196
branching involved in open tracheal system development GO:0060446 45 0.192
regulation of mapk cascade GO:0043408 92 0.184
positive regulation of biosynthetic process GO:0009891 316 0.182
Mouse
regulation of cell shape GO:0008360 113 0.181
positive regulation of cellular component biogenesis GO:0044089 80 0.180
Human
regulation of protein kinase activity GO:0045859 51 0.180
immune response GO:0006955 246 0.179
enzyme linked receptor protein signaling pathway GO:0007167 179 0.177
Human Mouse
negative regulation of signaling GO:0023057 219 0.175
ribonucleotide metabolic process GO:0009259 145 0.174
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.167
Mouse
morphogenesis of a polarized epithelium GO:0001738 93 0.162
circadian behavior GO:0048512 76 0.162
regulation of catalytic activity GO:0050790 185 0.161
appendage development GO:0048736 401 0.160
cellular catabolic process GO:0044248 372 0.153
regulation of protein metabolic process GO:0051246 256 0.151
nephron tubule morphogenesis GO:0072078 3 0.150
anterior posterior axis specification GO:0009948 109 0.147
nucleoside triphosphate metabolic process GO:0009141 120 0.146
Human
regulation of secretion GO:0051046 44 0.144
regulation of cell cycle process GO:0010564 181 0.144
non sensory hair organization GO:0035316 47 0.144
oxoacid metabolic process GO:0043436 103 0.143
open tracheal system development GO:0007424 204 0.141
purine nucleoside triphosphate catabolic process GO:0009146 108 0.140
Human
regulation of organelle organization GO:0033043 196 0.137
stress activated protein kinase signaling cascade GO:0031098 55 0.134
neuron fate commitment GO:0048663 50 0.130
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.129
Human
purine nucleoside catabolic process GO:0006152 112 0.129
Human
chaeta development GO:0022416 97 0.129
establishment of cell polarity GO:0030010 40 0.129
synaptic transmission GO:0007268 288 0.127
neuroblast division GO:0055057 35 0.126
dorsal ventral pattern formation GO:0009953 133 0.125
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.125
response to hormone GO:0009725 45 0.124
Human Mouse
positive regulation of cell communication GO:0010647 250 0.124
Mouse
semaphorin plexin signaling pathway GO:0071526 4 0.123
negative regulation of cell development GO:0010721 62 0.122
Mouse Rat
compound eye photoreceptor cell differentiation GO:0001751 140 0.121
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.120
epidermal cell differentiation GO:0009913 51 0.119
dna replication GO:0006260 48 0.117
eye photoreceptor cell differentiation GO:0001754 145 0.116
epithelial cell migration GO:0010631 148 0.115
purine containing compound metabolic process GO:0072521 155 0.113
Human Mouse
protein catabolic process GO:0030163 101 0.113
intracellular transport GO:0046907 228 0.110
Human Mouse
heart morphogenesis GO:0003007 32 0.104
Mouse
r3 r4 cell fate commitment GO:0007464 10 0.103
regulation of cellular component size GO:0032535 98 0.103
Mouse
cellular homeostasis GO:0019725 80 0.102
positive regulation of catalytic activity GO:0043085 118 0.101
Human Mouse
regulation of intracellular signal transduction GO:1902531 236 0.100
regulation of cell differentiation GO:0045595 302 0.100
positive regulation of cellular protein metabolic process GO:0032270 118 0.099
positive regulation of proteolysis GO:0045862 52 0.098
regulation of cellular protein metabolic process GO:0032268 243 0.097
covalent chromatin modification GO:0016569 106 0.097
positive regulation of cellular biosynthetic process GO:0031328 316 0.096
Mouse
anterior posterior pattern specification GO:0009952 136 0.095
regulation of phosphorylation GO:0042325 147 0.094
meiotic nuclear envelope disassembly GO:0051078 2 0.093
digestive tract development GO:0048565 149 0.092
regulation of organ morphogenesis GO:2000027 78 0.091
positive regulation of cell differentiation GO:0045597 64 0.090
Mouse
nucleobase containing compound catabolic process GO:0034655 165 0.090
Human
cell fate specification GO:0001708 71 0.089
embryonic development via the syncytial blastoderm GO:0001700 148 0.089
organic substance catabolic process GO:1901575 308 0.087
positive regulation of phosphorus metabolic process GO:0010562 139 0.087
Human Mouse
regulation of stress activated mapk cascade GO:0032872 41 0.087
glycosyl compound catabolic process GO:1901658 112 0.087
Human
response to nitrogen compound GO:1901698 90 0.086
Human Mouse
establishment of planar polarity GO:0001736 87 0.086
regulation of cell death GO:0010941 173 0.085
Human Mouse Rat
unsaturated fatty acid biosynthetic process GO:0006636 1 0.084
organic cyclic compound catabolic process GO:1901361 168 0.082
Human
regulation of neuron projection development GO:0010975 69 0.082
Mouse Rat
meiotic cell cycle GO:0051321 171 0.080
negative regulation of rna biosynthetic process GO:1902679 240 0.078
imaginal disc growth GO:0007446 37 0.078
morphogenesis of embryonic epithelium GO:0016331 94 0.077
actin cytoskeleton organization GO:0030036 206 0.076
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.076
Mouse Rat
digestive system development GO:0055123 149 0.075
somatic stem cell division GO:0048103 37 0.074
macromolecular complex assembly GO:0065003 256 0.074
Human
immune system process GO:0002376 347 0.074
dephosphorylation GO:0016311 51 0.073
purine nucleotide catabolic process GO:0006195 109 0.072
Human
cell death GO:0008219 279 0.072
Human Mouse Rat
morphogenesis of an epithelium GO:0002009 276 0.072
nucleobase containing small molecule metabolic process GO:0055086 174 0.071
Human Mouse
response to inorganic substance GO:0010035 44 0.071
Mouse Rat
male sex differentiation GO:0046661 25 0.071
Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.071
Human Mouse
nucleoside monophosphate metabolic process GO:0009123 52 0.071
neuronal stem cell division GO:0036445 35 0.070
plasma membrane organization GO:0007009 26 0.070
axon choice point recognition GO:0016198 26 0.069
meiotic cell cycle process GO:1903046 132 0.068
negative regulation of meiotic cell cycle phase transition GO:1901994 1 0.067
positive regulation of synapse assembly GO:0051965 29 0.067
multicellular organismal reproductive behavior GO:0033057 110 0.067
nephron development GO:0072006 3 0.066
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.066
gastrulation with mouth forming first GO:0001703 36 0.066
tissue morphogenesis GO:0048729 297 0.066
transmembrane transport GO:0055085 139 0.065
regulation of actin cytoskeleton organization GO:0032956 42 0.065
segmentation GO:0035282 207 0.064
oocyte morphogenesis GO:0048601 3 0.064
regulation of phosphate metabolic process GO:0019220 210 0.064
cellular response to dna damage stimulus GO:0006974 223 0.063
dendrite regeneration GO:0031104 2 0.062
protein localization GO:0008104 284 0.061
Human Mouse Worm
muscle organ development GO:0007517 127 0.061
Mouse
mitotic cell cycle phase transition GO:0044772 138 0.061
hemocyte differentiation GO:0042386 38 0.060
negative regulation of cell death GO:0060548 81 0.060
Human Mouse
nitrogen compound transport GO:0071705 85 0.060
single organism carbohydrate metabolic process GO:0044723 72 0.060
Human
phosphorylation GO:0016310 294 0.059
body morphogenesis GO:0010171 2 0.059
atp metabolic process GO:0046034 49 0.058
eye photoreceptor cell development GO:0042462 81 0.058
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.058
Human
mapk cascade GO:0000165 107 0.057
negative regulation of mitotic anaphase promoting complex activity GO:0060564 2 0.057
cuticle development GO:0042335 86 0.057
protein complex assembly GO:0006461 200 0.056
Human
central nervous system development GO:0007417 201 0.056
Human
icosanoid biosynthetic process GO:0046456 1 0.056
chromatin remodeling at centromere GO:0031055 3 0.056
regulation of neurotransmitter levels GO:0001505 38 0.056
mating GO:0007618 120 0.055
protein modification process GO:0036211 438 0.055
purine nucleotide metabolic process GO:0006163 146 0.054
Human Mouse
biological adhesion GO:0022610 138 0.054
Human
protein transport GO:0015031 155 0.053
Human Mouse
regulation of neurogenesis GO:0050767 158 0.053
Mouse Rat
regulation of epithelial cell proliferation GO:0050678 4 0.053
oocyte axis specification GO:0007309 108 0.050
regulation of vesicle mediated transport GO:0060627 59 0.050
dorsal ventral axis specification GO:0009950 66 0.050
transcription from rna polymerase ii promoter GO:0006366 368 0.050
Mouse
exocrine system development GO:0035272 162 0.049
regulation of cell proliferation involved in compound eye morphogenesis GO:2000495 2 0.048
cardiovascular system development GO:0072358 82 0.048
Mouse
cellular amine metabolic process GO:0044106 12 0.048
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 2 0.048
ovarian follicle cell development GO:0030707 248 0.048
epithelial tube morphogenesis GO:0060562 88 0.047
centrosome cycle GO:0007098 137 0.047
regulation of imaginal disc growth GO:0045570 26 0.046
meiotic spindle checkpoint GO:0044779 1 0.046
regulation of protein complex assembly GO:0043254 42 0.045
Human
wing disc pattern formation GO:0035222 66 0.045
regulation of synapse organization GO:0050807 110 0.045
stem cell division GO:0017145 69 0.044
regulation of mitotic cell cycle GO:0007346 190 0.044
organophosphate metabolic process GO:0019637 195 0.044
Human Mouse
compound eye photoreceptor fate commitment GO:0001752 36 0.044
dendrite development GO:0016358 204 0.043
Rat
purine containing compound catabolic process GO:0072523 112 0.043
Human
ion transmembrane transport GO:0034220 122 0.043
cell fate determination GO:0001709 91 0.043
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.042
signal release GO:0023061 49 0.042
neurotransmitter transport GO:0006836 37 0.042
stem cell maintenance GO:0019827 67 0.042
maternal determination of dorsal ventral axis ovarian follicular epithelium germ line encoded GO:0008070 2 0.040
retinal ganglion cell axon guidance GO:0031290 12 0.040
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded GO:0008071 1 0.040
meiotic dna repair synthesis GO:0000711 3 0.040
catabolic process GO:0009056 409 0.040
negative regulation of cellular component organization GO:0051129 108 0.039
oocyte fate commitment GO:0048600 2 0.039
negative regulation of developmental growth GO:0048640 64 0.038
associative learning GO:0008306 65 0.038
defense response to other organism GO:0098542 225 0.037
anterior head segmentation GO:0035288 3 0.037
epithelial cell fate determination open tracheal system GO:0007425 2 0.037
wing disc morphogenesis GO:0007472 344 0.036
cell cell signaling involved in cell fate commitment GO:0045168 210 0.036
regulation of cellular ketone metabolic process GO:0010565 3 0.036
negative regulation of transcription from rna polymerase iii promoter GO:0016480 2 0.036
maintenance of protein location GO:0045185 28 0.035
positive regulation of signaling GO:0023056 243 0.035
Mouse
positive regulation of chromatin silencing at telomere GO:0031940 2 0.035
response to biotic stimulus GO:0009607 294 0.035
Human Mouse
regulation of catabolic process GO:0009894 170 0.035
regulation of multicellular organism growth GO:0040014 40 0.034
photoreceptor cell development GO:0042461 96 0.034
regulation of cellular response to stress GO:0080135 89 0.034
protein localization to organelle GO:0033365 82 0.034
Human Mouse
peptidyl amino acid modification GO:0018193 105 0.034
Human Mouse Worm
cellular protein localization GO:0034613 160 0.034
Human Mouse
ribonucleoside triphosphate metabolic process GO:0009199 119 0.034
Human
chromatin modification GO:0016568 147 0.033
regulation of response to external stimulus GO:0032101 115 0.033
regulation of response to stress GO:0080134 200 0.033
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.032
intracellular protein transport GO:0006886 104 0.032
Human Mouse
organonitrogen compound catabolic process GO:1901565 128 0.032
Human
regulation of protein stability GO:0031647 43 0.032
hematopoietic stem cell differentiation GO:0060218 1 0.031
p granule organization GO:0030719 4 0.031
regulation of rac gtpase activity GO:0032314 1 0.031
vesicle mediated transport GO:0016192 381 0.031
Worm
ribonucleoside triphosphate catabolic process GO:0009203 108 0.031
Human
cellular nitrogen compound catabolic process GO:0044270 165 0.031
Human
r3 r4 cell differentiation GO:0048056 12 0.031
nucleoside phosphate metabolic process GO:0006753 162 0.030
Human Mouse
cellular protein catabolic process GO:0044257 83 0.030
establishment of ommatidial planar polarity GO:0042067 49 0.030
positive regulation of golgi to plasma membrane protein transport GO:0042998 2 0.030
tissue migration GO:0090130 155 0.030
positive regulation of wnt signaling pathway GO:0030177 25 0.029
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.029
cell recognition GO:0008037 102 0.029
regulation of reproductive process GO:2000241 54 0.029
carbohydrate derivative biosynthetic process GO:1901137 85 0.029
Mouse
notch signaling pathway GO:0007219 120 0.029
negative regulation of terminal cell fate specification open tracheal system GO:0035155 2 0.029
positive regulation of phosphorylation GO:0042327 87 0.029
Mouse
apoptotic process GO:0006915 159 0.028
Human Mouse Rat
dna integration GO:0015074 1 0.028
imaginal disc derived leg morphogenesis GO:0007480 80 0.028
detection of virus GO:0009597 1 0.028
regulation of gene expression by genetic imprinting GO:0006349 1 0.028
Mouse
defense response to bacterium GO:0042742 178 0.028
negative regulation of wnt signaling pathway GO:0030178 28 0.027
Worm
detection of stimulus GO:0051606 156 0.027
nucleoside triphosphate catabolic process GO:0009143 108 0.027
Human
cellular response to chemical stimulus GO:0070887 199 0.027
Human Mouse
kidney epithelium development GO:0072073 3 0.027
embryonic axis specification GO:0000578 107 0.027
single organism membrane organization GO:0044802 93 0.027
Mouse
response to oxygen containing compound GO:1901700 200 0.026
Human Mouse
nephron tubule development GO:0072080 3 0.026
positive regulation of transcription involved in g2 m transition of mitotic cell cycle GO:0090282 1 0.026
establishment of epithelial cell apical basal polarity GO:0045198 10 0.026
dna templated transcriptional start site selection GO:0001173 1 0.026
regulation of ran gtpase activity GO:0032316 1 0.026
specification of segmental identity antennal segment GO:0007383 2 0.025
negative regulation of growth GO:0045926 84 0.025
larval development GO:0002164 104 0.025
establishment of protein localization GO:0045184 163 0.025
Human Mouse
cellular response to organic substance GO:0071310 132 0.025
Human Mouse
establishment of spindle localization GO:0051293 22 0.025
Worm
regulation of neuron differentiation GO:0045664 103 0.025
Mouse Rat
cell cycle checkpoint GO:0000075 95 0.025
camera type eye development GO:0043010 4 0.025
negative regulation of cell cycle process GO:0010948 109 0.024
lipid localization GO:0010876 54 0.024
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.024
regulation of meiotic cell cycle phase transition GO:1901993 1 0.024
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.024
regulation of cellular localization GO:0060341 136 0.024
Human Mouse Worm
negative regulation of mrna 3 end processing GO:0031441 3 0.023
fatty acid derivative biosynthetic process GO:1901570 1 0.023
negative regulation of nucleotide catabolic process GO:0030812 1 0.023
positive regulation of cellular amine metabolic process GO:0033240 0 0.023
cell migration GO:0016477 238 0.023
Mouse Worm
reproductive structure development GO:0048608 74 0.023
Worm Fly
rhythmic process GO:0048511 106 0.023
negative regulation of dna templated transcription initiation GO:2000143 1 0.023
regulation of centriole replication GO:0046599 2 0.023
multi multicellular organism process GO:0044706 123 0.023
regulation of cohesin localization to chromatin GO:0071922 2 0.022
neuromuscular synaptic transmission GO:0007274 67 0.022
regulation of transferase activity GO:0051338 58 0.022
positive regulation of mapk cascade GO:0043410 63 0.022
organophosphate catabolic process GO:0046434 112 0.022
Human
wing disc dorsal ventral pattern formation GO:0048190 47 0.022
humoral immune response GO:0006959 117 0.022
neural precursor cell proliferation GO:0061351 75 0.022
asymmetric protein localization GO:0008105 33 0.022
nephron epithelium morphogenesis GO:0072088 3 0.022
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051436 2 0.021
columnar cuboidal epithelial cell development GO:0002066 249 0.021
response to organic cyclic compound GO:0014070 89 0.021
Mouse
positive regulation of protein localization to plasma membrane GO:1903078 3 0.021
embryonic organ morphogenesis GO:0048562 5 0.021
regulation of jnk cascade GO:0046328 40 0.021
meiotic nuclear division GO:0007126 151 0.021
spinal cord development GO:0021510 1 0.021
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.021
regulation of spindle checkpoint GO:0090231 2 0.021
positive regulation of cell growth GO:0030307 19 0.021
Mouse

sgg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.100
nervous system disease DOID:863 0 0.092
artery disease DOID:0050828 0 0.043
cardiovascular system disease DOID:1287 0 0.043
aortic aneurysm DOID:3627 0 0.043
aortic disease DOID:520 0 0.043
vascular disease DOID:178 0 0.043
cancer DOID:162 0 0.033
disease of cellular proliferation DOID:14566 0 0.033
organ system cancer DOID:0050686 0 0.033
thyroid carcinoma DOID:3963 0 0.026
thyroid cancer DOID:1781 0 0.026
follicular thyroid carcinoma DOID:3962 0 0.026
endocrine gland cancer DOID:170 0 0.026
familial meningioma DOID:4586 0 0.023
meningioma DOID:3565 0 0.023
central nervous system cancer DOID:3620 0 0.023
nervous system cancer DOID:3093 0 0.023