Drosophila melanogaster

19 known processes

n-syb (Dmel_CG17248)

n-synaptobrevin

(Aliases: SYB,Dmel\CG17248,CG17248,N-Syb,N-syb,Syb62A,Dn-syb,Nsyb,syb,nsyb,nSYB,n-Syb,nSyb)

n-syb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 288 0.991
neuron neuron synaptic transmission GO:0007270 14 0.720
single organism membrane fusion GO:0044801 42 0.580
taxis GO:0042330 304 0.505
synaptic vesicle recycling GO:0036465 28 0.398
cognition GO:0050890 141 0.296
locomotory behavior GO:0007626 176 0.268
response to light stimulus GO:0009416 124 0.247
learning or memory GO:0007611 141 0.241
vesicle fusion GO:0006906 19 0.225
establishment of synaptic vesicle localization GO:0097480 50 0.214
response to radiation GO:0009314 155 0.213
regulation of multi organism process GO:0043900 131 0.195
synaptic vesicle endocytosis GO:0048488 28 0.194
regulation of synaptic transmission GO:0050804 69 0.190
membrane fusion GO:0061025 42 0.183
neuromuscular synaptic transmission GO:0007274 67 0.170
signal release GO:0023061 49 0.167
response to abiotic stimulus GO:0009628 341 0.162
single organism behavior GO:0044708 391 0.160
neurological system process GO:0050877 358 0.144
secretion by cell GO:0032940 101 0.144
synaptic vesicle transport GO:0048489 50 0.144
regulation of neurotransmitter levels GO:0001505 38 0.139
energy taxis GO:0009453 21 0.137
establishment of organelle localization GO:0051656 122 0.124
vesicle organization GO:0016050 44 0.116
regulation of pole plasm oskar mrna localization GO:0007317 27 0.115
neurotransmitter transport GO:0006836 37 0.112
establishment of vesicle localization GO:0051650 51 0.112
ion transmembrane transport GO:0034220 122 0.108
establishment of localization in cell GO:0051649 402 0.105
sensory perception GO:0007600 196 0.099
regulation of epithelial cell proliferation GO:0050678 4 0.098
vesicle localization GO:0051648 55 0.087
sensory perception of sound GO:0007605 56 0.080
secretion GO:0046903 109 0.079
vesicle mediated transport GO:0016192 381 0.078
rhythmic behavior GO:0007622 76 0.077
cell maturation GO:0048469 144 0.073
adult behavior GO:0030534 137 0.073
axis specification GO:0009798 167 0.070
neurotransmitter secretion GO:0007269 35 0.069
tube development GO:0035295 244 0.068
developmental maturation GO:0021700 172 0.067
regulation of oocyte development GO:0060281 27 0.066
vitamin transport GO:0051180 2 0.065
regulation of embryonic pattern specification GO:1902875 27 0.065
organonitrogen compound metabolic process GO:1901564 318 0.065
response to monosaccharide GO:0034284 4 0.063
regulation of neurotransmitter secretion GO:0046928 14 0.062
phototaxis GO:0042331 21 0.060
organic acid metabolic process GO:0006082 103 0.059
axon guidance GO:0007411 233 0.059
cell cell junction assembly GO:0007043 38 0.057
regulation of cell cycle GO:0051726 291 0.056
endomembrane system organization GO:0010256 119 0.055
forebrain development GO:0030900 2 0.055
regulation of multicellular organismal development GO:2000026 414 0.054
regulation of localization GO:0032879 275 0.053
regulation of transport GO:0051049 181 0.053
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.052
protein complex assembly GO:0006461 200 0.050
membrane organization GO:0061024 112 0.050
synaptic vesicle localization GO:0097479 53 0.050
regulation of behavior GO:0050795 75 0.049
organic substance transport GO:0071702 257 0.046
endocytosis GO:0006897 310 0.046
response to temperature stimulus GO:0009266 106 0.045
detection of chemical stimulus GO:0009593 93 0.045
response to heat GO:0009408 63 0.043
synaptic vesicle exocytosis GO:0016079 16 0.043
oxoacid metabolic process GO:0043436 103 0.043
g protein coupled receptor signaling pathway GO:0007186 136 0.042
regulation of cell maturation GO:1903429 27 0.042
regulation of cellular component biogenesis GO:0044087 201 0.041
macromolecular complex assembly GO:0065003 256 0.040
apical junction assembly GO:0043297 32 0.040
associative learning GO:0008306 65 0.040
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.040
positive regulation of synaptic transmission GO:0050806 15 0.039
neurotransmitter metabolic process GO:0042133 2 0.038
l amino acid import GO:0043092 2 0.038
regulation of response to external stimulus GO:0032101 115 0.038
single organism cellular localization GO:1902580 180 0.038
regulation of cell differentiation GO:0045595 302 0.037
regulation of reproductive process GO:2000241 54 0.037
cellular amino acid metabolic process GO:0006520 61 0.037
ion transport GO:0006811 145 0.036
actin filament based process GO:0030029 220 0.036
rna localization GO:0006403 115 0.035
regulation of cellular localization GO:0060341 136 0.035
regulation of synapse organization GO:0050807 110 0.035
regulation of protein metabolic process GO:0051246 256 0.035
alpha amino acid metabolic process GO:1901605 20 0.034
macromolecule catabolic process GO:0009057 161 0.034
regionalization GO:0003002 416 0.034
transmembrane transport GO:0055085 139 0.034
flight behavior GO:0007629 26 0.034
negative regulation of epithelial cell proliferation GO:0050680 4 0.033
memory GO:0007613 94 0.033
organophosphate metabolic process GO:0019637 195 0.033
catabolic process GO:0009056 409 0.033
positive regulation of response to stimulus GO:0048584 323 0.032
phosphorylation GO:0016310 294 0.032
glutamine family amino acid catabolic process GO:0009065 3 0.032
receptor clustering GO:0043113 3 0.031
proteolysis GO:0006508 192 0.031
response to oxygen containing compound GO:1901700 200 0.031
intracellular mrna localization GO:0008298 66 0.031
sensory perception of smell GO:0007608 80 0.031
small molecule catabolic process GO:0044282 21 0.030
adult locomotory behavior GO:0008344 76 0.030
organic substance catabolic process GO:1901575 308 0.030
spindle assembly GO:0051225 80 0.030
respiratory system development GO:0060541 213 0.030
carboxylic acid metabolic process GO:0019752 92 0.030
defense response GO:0006952 300 0.029
response to glucose GO:0009749 2 0.029
oocyte axis specification GO:0007309 108 0.029
positive regulation of signaling GO:0023056 243 0.029
regulation of secretion by cell GO:1903530 39 0.029
regulation of mitotic cell cycle phase transition GO:1901990 130 0.028
synaptic transmission glutamatergic GO:0035249 7 0.028
synapse assembly GO:0007416 143 0.028
organonitrogen compound catabolic process GO:1901565 128 0.028
positive regulation of neurotransmitter secretion GO:0001956 2 0.027
epithelial cell differentiation GO:0030855 322 0.027
pole plasm mrna localization GO:0019094 49 0.027
negative regulation of gene expression GO:0010629 387 0.027
developmental growth GO:0048589 280 0.027
regulation of organelle organization GO:0033043 196 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
regulation of system process GO:0044057 36 0.026
cellular catabolic process GO:0044248 372 0.026
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.026
pole plasm oskar mrna localization GO:0045451 46 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.025
single organism membrane organization GO:0044802 93 0.025
segmentation GO:0035282 207 0.025
negative regulation of cellular metabolic process GO:0031324 382 0.025
embryonic morphogenesis GO:0048598 206 0.025
small molecule metabolic process GO:0044281 305 0.024
anterior posterior axis specification GO:0009948 109 0.024
organelle assembly GO:0070925 198 0.024
cellular macromolecule localization GO:0070727 220 0.024
open tracheal system development GO:0007424 204 0.024
sensory perception of chemical stimulus GO:0007606 116 0.024
chemotaxis GO:0006935 249 0.024
cellular amide metabolic process GO:0043603 80 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
synaptic transmission cholinergic GO:0007271 9 0.024
response to biotic stimulus GO:0009607 294 0.023
death GO:0016265 284 0.023
regulation of phosphate metabolic process GO:0019220 210 0.023
regulation of response to stress GO:0080134 200 0.023
protein complex biogenesis GO:0070271 201 0.023
regulation of steroid metabolic process GO:0019218 2 0.022
peptide metabolic process GO:0006518 80 0.022
immune response GO:0006955 246 0.022
regulation of secretion GO:0051046 44 0.022
response to lipopolysaccharide GO:0032496 4 0.022
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.022
lipid modification GO:0030258 24 0.022
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.022
positive regulation of cell communication GO:0010647 250 0.021
l glutamate import GO:0051938 1 0.021
regulation of circadian rhythm GO:0042752 49 0.021
lateral inhibition GO:0046331 206 0.021
cellular response to carbohydrate stimulus GO:0071322 4 0.021
regulation of synapse assembly GO:0051963 94 0.021
compound eye development GO:0048749 307 0.020
protein modification process GO:0036211 438 0.020
amine metabolic process GO:0009308 12 0.020
necrotic cell death GO:0070265 1 0.020
cell proliferation GO:0008283 299 0.020
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
pathway restricted smad protein phosphorylation GO:0060389 1 0.020
positive regulation of cellular biosynthetic process GO:0031328 316 0.020
regulation of neurogenesis GO:0050767 158 0.020
cellular response to hexose stimulus GO:0071331 1 0.020
protein catabolic process GO:0030163 101 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
response to other organism GO:0051707 293 0.019
embryonic pattern specification GO:0009880 174 0.019
positive regulation of synaptic vesicle endocytosis GO:1900244 4 0.019
response to hexose GO:0009746 3 0.019
anterior posterior pattern specification GO:0009952 136 0.019
oocyte differentiation GO:0009994 145 0.019
regulation of ion transmembrane transport GO:0034765 27 0.019
multi organism behavior GO:0051705 175 0.018
organelle fusion GO:0048284 46 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
phagocytosis GO:0006909 215 0.018
intracellular protein transmembrane transport GO:0065002 4 0.018
male gamete generation GO:0048232 201 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
regulation of molecular function GO:0065009 217 0.018
regulation of membrane potential GO:0042391 35 0.018
protein localization GO:0008104 284 0.018
multi multicellular organism process GO:0044706 123 0.018
circadian behavior GO:0048512 76 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
larval development GO:0002164 104 0.017
positive regulation of synaptic vesicle recycling GO:1903423 4 0.017
glial cell development GO:0021782 27 0.017
determination of adult lifespan GO:0008340 137 0.017
lipid localization GO:0010876 54 0.017
septate junction assembly GO:0019991 26 0.017
exocytosis GO:0006887 28 0.017
maternal determination of anterior posterior axis embryo GO:0008358 74 0.017
carboxylic acid catabolic process GO:0046395 16 0.017
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.017
regulation of cell cycle phase transition GO:1901987 130 0.017
rhythmic synaptic transmission GO:0060024 2 0.016
pole plasm rna localization GO:0007316 52 0.016
intraspecies interaction between organisms GO:0051703 4 0.016
mrna metabolic process GO:0016071 124 0.016
body morphogenesis GO:0010171 2 0.016
protein targeting GO:0006605 64 0.016
positive regulation of nervous system development GO:0051962 69 0.016
cellular protein modification process GO:0006464 438 0.016
limb development GO:0060173 1 0.016
immune response regulating signaling pathway GO:0002764 2 0.016
regulation of mapk cascade GO:0043408 92 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
positive regulation of synapse assembly GO:0051965 29 0.016
response to external biotic stimulus GO:0043207 293 0.016
multicellular organismal aging GO:0010259 140 0.016
organelle fission GO:0048285 340 0.016
telencephalon development GO:0021537 2 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
anterior posterior axis specification embryo GO:0008595 103 0.016
single organism catabolic process GO:0044712 228 0.015
reproductive behavior GO:0019098 122 0.015
head development GO:0060322 135 0.015
spermatogenesis GO:0007283 200 0.015
organelle localization GO:0051640 148 0.015
single organism biosynthetic process GO:0044711 206 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
regulation of nervous system development GO:0051960 248 0.015
chemosensory behavior GO:0007635 106 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
neurotransmitter receptor metabolic process GO:0045213 3 0.015
organic acid catabolic process GO:0016054 16 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
positive regulation of transport GO:0051050 92 0.015
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.015
epidermal growth factor receptor signaling pathway GO:0007173 58 0.015
spindle organization GO:0007051 253 0.015
biological adhesion GO:0022610 138 0.015
positive regulation of cgmp metabolic process GO:0030825 1 0.015
oocyte maturation GO:0001556 3 0.015
pole plasm assembly GO:0007315 61 0.015
male meiosis cytokinesis GO:0007112 26 0.015
establishment of protein localization GO:0045184 163 0.015
cell junction organization GO:0034330 57 0.014
carboxylic acid biosynthetic process GO:0046394 15 0.014
growth GO:0040007 359 0.014
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.014
cellular response to biotic stimulus GO:0071216 4 0.014
oocyte development GO:0048599 124 0.014
oxidation reduction process GO:0055114 123 0.014
regulation of vesicle mediated transport GO:0060627 59 0.014
camera type eye development GO:0043010 4 0.014
multi organism reproductive behavior GO:0044705 121 0.014
intracellular transport GO:0046907 228 0.014
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.014
cell junction assembly GO:0034329 42 0.014
response to nutrient levels GO:0031667 114 0.014
positive regulation of synaptic transmission glutamatergic GO:0051968 3 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
regulation of catalytic activity GO:0050790 185 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
mitotic spindle organization GO:0007052 220 0.014
positive regulation of signal transduction GO:0009967 223 0.014
immune system process GO:0002376 347 0.014
regulation of defense response GO:0031347 102 0.013
regulation of circadian sleep wake cycle GO:0042749 25 0.013
proteasomal protein catabolic process GO:0010498 59 0.013
negative regulation of kinase activity GO:0033673 16 0.013
regulation of response to biotic stimulus GO:0002831 63 0.013
regulation of synaptic vesicle exocytosis GO:2000300 3 0.013
spermatid differentiation GO:0048515 114 0.013
cell death GO:0008219 279 0.013
regulation of synaptic vesicle endocytosis GO:1900242 7 0.013
cellular ketone metabolic process GO:0042180 24 0.013
detection of stimulus GO:0051606 156 0.013
hindgut morphogenesis GO:0007442 58 0.013
mitotic nuclear division GO:0007067 213 0.013
cation transport GO:0006812 110 0.013
cellular protein catabolic process GO:0044257 83 0.013
positive regulation of cell migration GO:0030335 2 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.013
modification dependent protein catabolic process GO:0019941 78 0.013
microtubule based movement GO:0007018 51 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
synaptic vesicle priming GO:0016082 1 0.013
sensory perception of mechanical stimulus GO:0050954 72 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
membrane depolarization GO:0051899 4 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
protein maturation GO:0051604 71 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
positive regulation of cell motility GO:2000147 3 0.012
long term memory GO:0007616 62 0.012
rna processing GO:0006396 147 0.012
regulated secretory pathway GO:0045055 1 0.012
cellular amine metabolic process GO:0044106 12 0.012
cell cycle arrest GO:0007050 4 0.012
ameboidal type cell migration GO:0001667 151 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
circadian sleep wake cycle process GO:0022410 24 0.012
rhythmic excitation GO:0043179 1 0.012
tripartite regional subdivision GO:0007351 103 0.012
positive regulation of behavior GO:0048520 19 0.012
circadian sleep wake cycle sleep GO:0050802 23 0.012
microtubule organizing center organization GO:0031023 168 0.012
response to oxygen levels GO:0070482 59 0.012
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.011
gliogenesis GO:0042063 80 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
anatomical structure homeostasis GO:0060249 97 0.011
carbohydrate derivative biosynthetic process GO:1901137 85 0.011
regulation of cell death GO:0010941 173 0.011
regulation of synaptic plasticity GO:0048167 14 0.011
protein processing GO:0016485 68 0.011
learning GO:0007612 75 0.011
developmental growth involved in morphogenesis GO:0060560 65 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
cortical cytoskeleton organization GO:0030865 29 0.011
peripheral nervous system development GO:0007422 52 0.011
membrane tubulation GO:0097320 4 0.011
response to bacterium GO:0009617 198 0.011
choline catabolic process GO:0042426 1 0.011
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
hindgut development GO:0061525 58 0.011
negative regulation of hormone biosynthetic process GO:0032353 1 0.011
posttranscriptional gene silencing GO:0016441 46 0.011
regulation of neurotransmitter transport GO:0051588 14 0.011
sensory organ morphogenesis GO:0090596 260 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.011
cellular lipid metabolic process GO:0044255 83 0.011
positive regulation of multi organism process GO:0043902 40 0.011
hindbrain development GO:0030902 2 0.011
negative regulation of molecular function GO:0044092 51 0.011
response to calcium ion GO:0051592 1 0.011
regulation of cell cycle process GO:0010564 181 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
synapse organization GO:0050808 196 0.011
imaginal disc growth GO:0007446 37 0.011
regulation of synaptic transmission glutamatergic GO:0051966 5 0.011
positive regulation of exocytosis GO:0045921 4 0.011
detection of external stimulus GO:0009581 66 0.011
cell division GO:0051301 248 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
lipid metabolic process GO:0006629 121 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
feeding behavior GO:0007631 50 0.010
heart process GO:0003015 37 0.010
dorsal ventral axis specification GO:0009950 66 0.010
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 9 0.010
mitochondrion organization GO:0007005 65 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.010
positive regulation of apoptotic signaling pathway GO:2001235 4 0.010
negative regulation of cell cycle GO:0045786 116 0.010
regulation of locomotion GO:0040012 42 0.010
wound healing GO:0042060 75 0.010
cytokinesis GO:0000910 90 0.010
macromolecule methylation GO:0043414 45 0.010
regulation of cell development GO:0060284 215 0.010

n-syb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.019
nervous system disease DOID:863 0 0.018
artery disease DOID:0050828 0 0.014
vascular disease DOID:178 0 0.014
cardiovascular system disease DOID:1287 0 0.014
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
sensory system disease DOID:0050155 0 0.010