Drosophila melanogaster

48 known processes

spok (Dmel_CG41624)

spookier

(Aliases: Dmspok,307a2p,Dmel\CG41624,CG40123,spo2,Cyp307a2p,Cyp307a2Psi,Cyp307a2,CG41624)

spok biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule metabolic process GO:0044281 305 0.091
cellular ketone metabolic process GO:0042180 24 0.081
steroid biosynthetic process GO:0006694 16 0.049
lipid metabolic process GO:0006629 121 0.049
vesicle mediated transport GO:0016192 381 0.045
imaginal disc derived appendage morphogenesis GO:0035114 395 0.041
imaginal disc derived wing morphogenesis GO:0007476 337 0.038
cellular protein modification process GO:0006464 438 0.036
instar larval development GO:0002168 55 0.035
oxoacid metabolic process GO:0043436 103 0.035
hormone metabolic process GO:0042445 33 0.034
endocytosis GO:0006897 310 0.034
mitotic g2 m transition checkpoint GO:0044818 70 0.033
appendage development GO:0048736 401 0.033
imaginal disc derived appendage development GO:0048737 399 0.030
protein modification process GO:0036211 438 0.030
small molecule biosynthetic process GO:0044283 37 0.030
hormone biosynthetic process GO:0042446 20 0.030
mitotic nuclear division GO:0007067 213 0.029
organic acid metabolic process GO:0006082 103 0.029
cellular macromolecule localization GO:0070727 220 0.029
eye morphogenesis GO:0048592 260 0.028
humoral immune response GO:0006959 117 0.028
wing disc morphogenesis GO:0007472 344 0.028
organonitrogen compound metabolic process GO:1901564 318 0.028
epithelial cell differentiation GO:0030855 322 0.028
establishment of localization in cell GO:0051649 402 0.028
carboxylic acid metabolic process GO:0019752 92 0.027
death GO:0016265 284 0.027
regulation of cell death GO:0010941 173 0.027
regulation of multicellular organismal development GO:2000026 414 0.026
regulation of cell cycle process GO:0010564 181 0.026
regulation of cell cycle GO:0051726 291 0.026
compound eye development GO:0048749 307 0.026
nuclear division GO:0000280 332 0.026
positive regulation of response to stimulus GO:0048584 323 0.025
regulation of programmed cell death GO:0043067 152 0.025
tube morphogenesis GO:0035239 191 0.025
cellular amino acid metabolic process GO:0006520 61 0.025
regulation of cell cycle phase transition GO:1901987 130 0.025
post embryonic appendage morphogenesis GO:0035120 385 0.024
epithelial cell development GO:0002064 274 0.024
eye development GO:0001654 323 0.024
gland development GO:0048732 191 0.023
body morphogenesis GO:0010171 2 0.023
negative regulation of cell cycle phase transition GO:1901988 103 0.023
regionalization GO:0003002 416 0.023
growth GO:0040007 359 0.023
regulation of mitotic cell cycle GO:0007346 190 0.023
appendage morphogenesis GO:0035107 397 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
cell death GO:0008219 279 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
programmed cell death GO:0012501 257 0.022
single organism biosynthetic process GO:0044711 206 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
cellular amine metabolic process GO:0044106 12 0.022
g2 dna damage checkpoint GO:0031572 69 0.022
compound eye morphogenesis GO:0001745 249 0.022
regulation of nervous system development GO:0051960 248 0.022
positive regulation of signaling GO:0023056 243 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
amine metabolic process GO:0009308 12 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
mitotic cell cycle phase transition GO:0044772 138 0.021
cell proliferation GO:0008283 299 0.021
single organism intracellular transport GO:1902582 207 0.021
response to abiotic stimulus GO:0009628 341 0.021
lipid biosynthetic process GO:0008610 46 0.021
organic substance transport GO:0071702 257 0.021
cell cycle phase transition GO:0044770 140 0.021
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.021
ecdysteroid biosynthetic process GO:0045456 15 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.020
phosphorylation GO:0016310 294 0.020
regulation of protein metabolic process GO:0051246 256 0.020
protein localization GO:0008104 284 0.020
developmental pigmentation GO:0048066 68 0.020
multicellular organism growth GO:0035264 46 0.020
macromolecular complex assembly GO:0065003 256 0.019
positive regulation of macromolecule metabolic process GO:0010604 405 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
negative regulation of cell cycle process GO:0010948 109 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
salivary gland development GO:0007431 162 0.019
organelle fission GO:0048285 340 0.019
phagocytosis GO:0006909 215 0.019
regulation of cell proliferation GO:0042127 163 0.019
positive regulation of cell communication GO:0010647 250 0.019
single organism catabolic process GO:0044712 228 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.018
cell division GO:0051301 248 0.018
multicellular organismal aging GO:0010259 140 0.018
response to oxygen containing compound GO:1901700 200 0.018
ethanolamine containing compound metabolic process GO:0042439 4 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
negative regulation of transcription dna templated GO:0045892 237 0.018
columnar cuboidal epithelial cell development GO:0002066 249 0.018
single organism behavior GO:0044708 391 0.017
homeostatic process GO:0042592 199 0.017
axonogenesis GO:0007409 290 0.017
chaeta development GO:0022416 97 0.017
regulation of localization GO:0032879 275 0.017
innate immune response GO:0045087 144 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
spindle organization GO:0007051 253 0.017
tube development GO:0035295 244 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
negative regulation of mitotic cell cycle GO:0045930 109 0.017
tissue migration GO:0090130 155 0.017
aging GO:0007568 143 0.017
endomembrane system organization GO:0010256 119 0.017
photoreceptor cell differentiation GO:0046530 170 0.017
salivary gland morphogenesis GO:0007435 145 0.017
intracellular transport GO:0046907 228 0.017
mitotic g2 dna damage checkpoint GO:0007095 69 0.017
regulation of hormone levels GO:0010817 40 0.016
regulation of cell development GO:0060284 215 0.016
segmentation GO:0035282 207 0.016
determination of adult lifespan GO:0008340 137 0.016
cellular catabolic process GO:0044248 372 0.016
chromosome organization GO:0051276 360 0.016
tissue morphogenesis GO:0048729 297 0.016
respiratory system development GO:0060541 213 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.016
sensory organ morphogenesis GO:0090596 260 0.016
response to organic substance GO:0010033 284 0.016
organic substance catabolic process GO:1901575 308 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
negative regulation of cell communication GO:0010648 223 0.016
cell cycle checkpoint GO:0000075 95 0.016
actin filament based process GO:0030029 220 0.016
catabolic process GO:0009056 409 0.016
protein ubiquitination GO:0016567 70 0.016
response to lipopolysaccharide GO:0032496 4 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
regulation of mitotic cell cycle phase transition GO:1901990 130 0.016
regulation of epithelial cell differentiation GO:0030856 4 0.016
regulation of protein modification process GO:0031399 112 0.016
response to external biotic stimulus GO:0043207 293 0.016
anatomical structure homeostasis GO:0060249 97 0.016
exocrine system development GO:0035272 162 0.016
protein complex assembly GO:0006461 200 0.016
regulation of molecular function GO:0065009 217 0.016
hindbrain development GO:0030902 2 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.015
dna damage checkpoint GO:0000077 78 0.015
intracellular signal transduction GO:0035556 300 0.015
immune system process GO:0002376 347 0.015
spermatogenesis GO:0007283 200 0.015
negative regulation of signal transduction GO:0009968 206 0.015
immune response GO:0006955 246 0.015
limb development GO:0060173 1 0.015
regulation of organelle organization GO:0033043 196 0.015
establishment of protein localization GO:0045184 163 0.015
negative regulation of developmental process GO:0051093 201 0.015
cellularization GO:0007349 90 0.015
regulation of response to stress GO:0080134 200 0.015
cellular protein localization GO:0034613 160 0.015
regulation of catalytic activity GO:0050790 185 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
defense response GO:0006952 300 0.015
regulation of apoptotic process GO:0042981 130 0.015
negative regulation of biosynthetic process GO:0009890 277 0.015
ameboidal type cell migration GO:0001667 151 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
dna integrity checkpoint GO:0031570 81 0.015
wound healing GO:0042060 75 0.015
positive regulation of signal transduction GO:0009967 223 0.014
camera type eye development GO:0043010 4 0.014
open tracheal system development GO:0007424 204 0.014
cholesterol homeostasis GO:0042632 3 0.014
protein complex biogenesis GO:0070271 201 0.014
male gamete generation GO:0048232 201 0.014
dendrite morphogenesis GO:0048813 199 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
organic hydroxy compound metabolic process GO:1901615 83 0.014
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
negative regulation of cell cycle GO:0045786 116 0.014
response to other organism GO:0051707 293 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
larval development GO:0002164 104 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
cell recognition GO:0008037 102 0.014
cell motility GO:0048870 251 0.014
organelle assembly GO:0070925 198 0.014
cytoplasmic transport GO:0016482 130 0.014
connective tissue development GO:0061448 3 0.014
blastoderm segmentation GO:0007350 159 0.014
positive regulation of biosynthetic process GO:0009891 316 0.013
embryonic pattern specification GO:0009880 174 0.013
regulation of growth GO:0040008 233 0.013
proteolysis GO:0006508 192 0.013
actin cytoskeleton organization GO:0030036 206 0.013
sterol homeostasis GO:0055092 4 0.013
protein transport GO:0015031 155 0.013
ras protein signal transduction GO:0007265 88 0.013
mitotic dna integrity checkpoint GO:0044774 75 0.013
pigmentation GO:0043473 75 0.013
single organism cellular localization GO:1902580 180 0.013
regulation of multi organism process GO:0043900 131 0.013
regulation of transport GO:0051049 181 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
developmental programmed cell death GO:0010623 138 0.013
gland morphogenesis GO:0022612 145 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
golgi organization GO:0007030 66 0.013
mitotic sister chromatid segregation GO:0000070 87 0.013
chromatin organization GO:0006325 207 0.013
positive regulation of cell motility GO:2000147 3 0.013
spermatid differentiation GO:0048515 114 0.013
protein catabolic process GO:0030163 101 0.013
muscle organ development GO:0007517 127 0.013
central nervous system development GO:0007417 201 0.013
mitotic dna damage checkpoint GO:0044773 74 0.013
negative regulation of signaling GO:0023057 219 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
response to biotic stimulus GO:0009607 294 0.012
neurological system process GO:0050877 358 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
gastrulation GO:0007369 70 0.012
microtubule organizing center organization GO:0031023 168 0.012
peptidyl amino acid modification GO:0018193 105 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.012
organelle localization GO:0051640 148 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
cell adhesion GO:0007155 136 0.012
regulation of cell differentiation GO:0045595 302 0.012
cholesterol transport GO:0030301 2 0.012
negative regulation of gene expression GO:0010629 387 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
lateral inhibition GO:0046331 206 0.012
response to monosaccharide GO:0034284 4 0.012
dendrite development GO:0016358 204 0.012
axon development GO:0061564 297 0.012
mitotic spindle organization GO:0007052 220 0.012
nephron development GO:0072006 3 0.012
establishment of organelle localization GO:0051656 122 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
developmental growth GO:0048589 280 0.012
negative regulation of growth GO:0045926 84 0.012
regulation of sequestering of triglyceride GO:0010889 3 0.012
cellular amide metabolic process GO:0043603 80 0.012
notch signaling pathway GO:0007219 120 0.012
negative regulation of nervous system development GO:0051961 92 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
synaptic transmission GO:0007268 288 0.011
regulation of cellular localization GO:0060341 136 0.011
regulation of catabolic process GO:0009894 170 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
melanin metabolic process GO:0006582 47 0.011
apoptotic process GO:0006915 159 0.011
adult behavior GO:0030534 137 0.011
pigment metabolic process GO:0042440 84 0.011
regulation of immune system process GO:0002682 176 0.011
imaginal disc pattern formation GO:0007447 91 0.011
regulation of lipid transport GO:0032368 3 0.011
chromatin modification GO:0016568 147 0.011
neuron recognition GO:0008038 101 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
histolysis GO:0007559 102 0.011
protein modification by small protein conjugation GO:0032446 79 0.011
antimicrobial humoral response GO:0019730 99 0.011
mushroom body development GO:0016319 70 0.011
chromosome separation GO:0051304 42 0.011
leg disc development GO:0035218 92 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
mapk cascade GO:0000165 107 0.011
taxis GO:0042330 304 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
positive regulation of catabolic process GO:0009896 105 0.011
response to copper ion GO:0046688 4 0.011
rhythmic behavior GO:0007622 76 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
axis specification GO:0009798 167 0.011
biological adhesion GO:0022610 138 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
regulation of translation GO:0006417 56 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
embryonic morphogenesis GO:0048598 206 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
tissue death GO:0016271 102 0.010
protein maturation GO:0051604 71 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
negative regulation of cell death GO:0060548 81 0.010
organophosphate metabolic process GO:0019637 195 0.010
sister chromatid segregation GO:0000819 92 0.010
protein phosphorylation GO:0006468 169 0.010
salivary gland histolysis GO:0035070 88 0.010
neuron projection guidance GO:0097485 241 0.010
autophagic cell death GO:0048102 83 0.010
developmental maturation GO:0021700 172 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
morphogenesis of a polarized epithelium GO:0001738 93 0.010
regulation of protein localization GO:0032880 76 0.010
regulation of developmental growth GO:0048638 174 0.010
anion homeostasis GO:0055081 3 0.010
positive regulation of gene expression GO:0010628 290 0.010

spok disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
disease of metabolism DOID:0014667 0 0.016
disease of cellular proliferation DOID:14566 0 0.015
nervous system disease DOID:863 0 0.014
inherited metabolic disorder DOID:655 0 0.012
acquired metabolic disease DOID:0060158 0 0.010