Drosophila melanogaster

179 known processes

park (Dmel_CG10523)

parkin

(Aliases: Dmel\CG10523,dpk,CG10523,SD01679)

park biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotory behavior GO:0007626 176 1.000
adult locomotory behavior GO:0008344 76 0.993
intrinsic apoptotic signaling pathway GO:0097193 16 0.952
Human Mouse
adult behavior GO:0030534 137 0.938
single organism behavior GO:0044708 391 0.928
spermatid differentiation GO:0048515 114 0.886
apoptotic signaling pathway GO:0097190 27 0.870
Human Mouse
mitochondrial fusion GO:0008053 7 0.820
spermatid development GO:0007286 98 0.803
ectopic germ cell programmed cell death GO:0035234 8 0.789
enzyme linked receptor protein signaling pathway GO:0007167 179 0.784
mitochondrion organization GO:0007005 65 0.719
actin filament based process GO:0030029 220 0.707
Human
positive regulation of apoptotic signaling pathway GO:2001235 4 0.682
Mouse
protein modification process GO:0036211 438 0.641
mitochondrion degradation GO:0000422 8 0.568
male gamete generation GO:0048232 201 0.549
regulation of organelle organization GO:0033043 196 0.540
regulation of protein metabolic process GO:0051246 256 0.529
Human Mouse
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.493
negative regulation of cellular response to oxidative stress GO:1900408 1 0.486
Human
macromolecular complex assembly GO:0065003 256 0.462
establishment of localization in cell GO:0051649 402 0.453
Human Mouse
negative regulation of response to stimulus GO:0048585 258 0.444
positive regulation of proteolysis GO:0045862 52 0.440
Human Mouse
epithelial cell development GO:0002064 274 0.428
protein modification by small protein conjugation or removal GO:0070647 106 0.374
cellular catabolic process GO:0044248 372 0.368
ribose phosphate metabolic process GO:0019693 145 0.365
protein modification by small protein conjugation GO:0032446 79 0.364
purine ribonucleoside metabolic process GO:0046128 127 0.344
negative regulation of cell communication GO:0010648 223 0.344
segmentation GO:0035282 207 0.338
regulation of cellular response to oxidative stress GO:1900407 4 0.325
developmental growth GO:0048589 280 0.320
oxidative phosphorylation GO:0006119 9 0.317
cellular protein modification process GO:0006464 438 0.312
cellular respiration GO:0045333 26 0.308
negative regulation of signal transduction GO:0009968 206 0.287
energy derivation by oxidation of organic compounds GO:0015980 32 0.287
growth GO:0040007 359 0.286
regulation of anatomical structure morphogenesis GO:0022603 242 0.285
ovarian follicle cell development GO:0030707 248 0.282
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.277
Human
regulation of response to oxidative stress GO:1902882 4 0.274
proteolysis GO:0006508 192 0.274
tissue migration GO:0090130 155 0.274
positive regulation of signal transduction GO:0009967 223 0.252
Human Mouse
blastoderm segmentation GO:0007350 159 0.250
purine containing compound metabolic process GO:0072521 155 0.249
positive regulation of programmed cell death GO:0043068 62 0.247
Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.247
organic substance catabolic process GO:1901575 308 0.245
spermatogenesis GO:0007283 200 0.243
organelle assembly GO:0070925 198 0.238
cell division GO:0051301 248 0.229
Worm
single organism membrane fusion GO:0044801 42 0.223
purine nucleoside metabolic process GO:0042278 127 0.223
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.204
embryonic pattern specification GO:0009880 174 0.201
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.197
regulation of cellular component movement GO:0051270 42 0.196
Worm
regulation of cellular protein metabolic process GO:0032268 243 0.194
Human Mouse
negative regulation of signaling GO:0023057 219 0.190
positive regulation of developmental process GO:0051094 143 0.190
death GO:0016265 284 0.184
Human Mouse
oxidation reduction process GO:0055114 123 0.183
somatic muscle development GO:0007525 66 0.177
generation of precursor metabolites and energy GO:0006091 42 0.173
negative regulation of neuron death GO:1901215 18 0.169
Human Mouse
membrane organization GO:0061024 112 0.166
glycosyl compound metabolic process GO:1901657 127 0.166
purine ribonucleotide metabolic process GO:0009150 145 0.165
purine nucleoside monophosphate metabolic process GO:0009126 50 0.162
synaptic transmission dopaminergic GO:0001963 2 0.159
Mouse
nucleoside monophosphate metabolic process GO:0009123 52 0.157
positive regulation of biosynthetic process GO:0009891 316 0.155
Human
ribonucleoside triphosphate metabolic process GO:0009199 119 0.155
regulation of cellular localization GO:0060341 136 0.155
Human Mouse
response to reactive oxygen species GO:0000302 24 0.153
tissue morphogenesis GO:0048729 297 0.153
homeostatic process GO:0042592 199 0.152
actin cytoskeleton organization GO:0030036 206 0.148
Human
positive regulation of signaling GO:0023056 243 0.148
Human Mouse
protein complex biogenesis GO:0070271 201 0.147
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.146
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.144
programmed cell death GO:0012501 257 0.141
Human Mouse
protein ubiquitination GO:0016567 70 0.140
microtubule bundle formation GO:0001578 27 0.140
atp metabolic process GO:0046034 49 0.138
ribonucleoside metabolic process GO:0009119 127 0.134
eye development GO:0001654 323 0.131
protein localization GO:0008104 284 0.131
Mouse
digestive tract morphogenesis GO:0048546 127 0.130
cilium morphogenesis GO:0060271 39 0.126
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.126
catabolic process GO:0009056 409 0.125
positive regulation of cellular biosynthetic process GO:0031328 316 0.123
Human
developmental maturation GO:0021700 172 0.120
regulation of cellular component biogenesis GO:0044087 201 0.120
Human
positive regulation of cell communication GO:0010647 250 0.118
Human Mouse
intracellular signal transduction GO:0035556 300 0.118
regulation of apoptotic process GO:0042981 130 0.118
Human Mouse
epithelial cell differentiation GO:0030855 322 0.116
organophosphate metabolic process GO:0019637 195 0.115
Human
cellular response to chemical stimulus GO:0070887 199 0.112
epithelium migration GO:0090132 148 0.112
protein complex assembly GO:0006461 200 0.112
regulation of growth GO:0040008 233 0.111
epithelial cell migration GO:0010631 148 0.111
regulation of proteolysis GO:0030162 87 0.111
Human Mouse
response to oxidative stress GO:0006979 86 0.110
single organism cellular localization GO:1902580 180 0.108
purine nucleoside triphosphate metabolic process GO:0009144 119 0.102
regulation of microtubule based process GO:0032886 49 0.101
ovarian follicle cell migration GO:0007297 121 0.101
cell migration GO:0016477 238 0.101
Worm
ribonucleotide metabolic process GO:0009259 145 0.098
nucleoside triphosphate metabolic process GO:0009141 120 0.098
cell motility GO:0048870 251 0.097
Worm
embryonic axis specification GO:0000578 107 0.097
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.097
positive regulation of apoptotic process GO:0043065 47 0.096
Mouse
regulation of apoptotic signaling pathway GO:2001233 10 0.094
Human Mouse
positive regulation of endopeptidase activity GO:0010950 26 0.094
regulation of intracellular signal transduction GO:1902531 236 0.093
protein maturation GO:0051604 71 0.092
regulation of catabolic process GO:0009894 170 0.091
Human Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.091
cellular component assembly involved in morphogenesis GO:0010927 151 0.091
positive regulation of macromolecule metabolic process GO:0010604 405 0.091
Human Mouse
flight behavior GO:0007629 26 0.091
regulation of cysteine type endopeptidase activity GO:2000116 27 0.091
negative regulation of developmental process GO:0051093 201 0.090
eye morphogenesis GO:0048592 260 0.090
organic substance transport GO:0071702 257 0.090
Human Mouse
positive regulation of gene expression GO:0010628 290 0.090
Human
single organism intracellular transport GO:1902582 207 0.090
circadian behavior GO:0048512 76 0.089
transcription from rna polymerase ii promoter GO:0006366 368 0.089
Human
activation of cysteine type endopeptidase activity GO:0097202 17 0.088
organelle fission GO:0048285 340 0.087
regulation of anatomical structure size GO:0090066 163 0.087
response to oxygen radical GO:0000305 3 0.085
regulation of cell death GO:0010941 173 0.084
Human Mouse
localization of cell GO:0051674 257 0.081
Worm
regulation of cell cycle GO:0051726 291 0.081
purine nucleotide metabolic process GO:0006163 146 0.080
purine nucleoside triphosphate catabolic process GO:0009146 108 0.080
nucleoside phosphate metabolic process GO:0006753 162 0.078
positive regulation of protein metabolic process GO:0051247 128 0.074
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.073
Human
zinc ion homeostasis GO:0055069 6 0.073
regionalization GO:0003002 416 0.070
circadian rhythm GO:0007623 105 0.070
response to abiotic stimulus GO:0009628 341 0.069
regulation of endopeptidase activity GO:0052548 36 0.066
regulation of hydrolase activity GO:0051336 97 0.065
macromolecule catabolic process GO:0009057 161 0.064
cellular response to organic substance GO:0071310 132 0.064
Human
developmental programmed cell death GO:0010623 138 0.063
positive regulation of peptidase activity GO:0010952 29 0.061
regulation of molecular function GO:0065009 217 0.061
Human
morphogenesis of an epithelium GO:0002009 276 0.061
intracellular transport GO:0046907 228 0.060
cytokinesis GO:0000910 90 0.060
Worm
regulation of multicellular organismal development GO:2000026 414 0.060
cell proliferation GO:0008283 299 0.060
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.060
purine ribonucleotide catabolic process GO:0009154 109 0.059
response to hydrogen peroxide GO:0042542 11 0.058
protein phosphorylation GO:0006468 169 0.058
Human
sperm axoneme assembly GO:0007288 13 0.057
positive regulation of response to stimulus GO:0048584 323 0.057
Human Mouse
regulation of protein modification process GO:0031399 112 0.057
Human Mouse
multicellular organism growth GO:0035264 46 0.057
ameboidal type cell migration GO:0001667 151 0.057
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.056
germarium derived egg chamber formation GO:0007293 101 0.056
regulation of cellular response to growth factor stimulus GO:0090287 13 0.056
microtubule based transport GO:0010970 42 0.056
ribonucleoside monophosphate catabolic process GO:0009158 39 0.055
sensory organ morphogenesis GO:0090596 260 0.055
response to starvation GO:0042594 97 0.054
regulation of cell projection organization GO:0031344 92 0.054
ovarian nurse cell to oocyte transport GO:0007300 27 0.053
regulation of cell differentiation GO:0045595 302 0.053
negative regulation of cellular biosynthetic process GO:0031327 277 0.053
cellular response to growth factor stimulus GO:0071363 30 0.052
negative regulation of cell cycle GO:0045786 116 0.052
regulation of cellular response to stress GO:0080135 89 0.052
axon development GO:0061564 297 0.052
purine nucleoside catabolic process GO:0006152 112 0.050
single organism membrane organization GO:0044802 93 0.049
neurological system process GO:0050877 358 0.049
Mouse
chemical homeostasis GO:0048878 92 0.048
morphogenesis of follicular epithelium GO:0016333 36 0.048
microtubule based movement GO:0007018 51 0.048
protein processing GO:0016485 68 0.047
regulation of cell development GO:0060284 215 0.046
carbohydrate derivative metabolic process GO:1901135 217 0.046
Human
regulation of multicellular organism growth GO:0040014 40 0.046
negative regulation of gene expression GO:0010629 387 0.046
regulation of transport GO:0051049 181 0.046
Human Mouse Worm
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.045
response to growth factor GO:0070848 31 0.044
regulation of response to stress GO:0080134 200 0.044
cellular response to reactive oxygen species GO:0034614 14 0.044
small molecule metabolic process GO:0044281 305 0.043
actomyosin structure organization GO:0031032 56 0.043
camera type eye development GO:0043010 4 0.042
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.042
regulation of mitochondrial fission GO:0090140 7 0.042
nucleoside metabolic process GO:0009116 127 0.042
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.042
positive regulation of cell death GO:0010942 69 0.041
Mouse
nucleobase containing compound catabolic process GO:0034655 165 0.041
nucleobase containing small molecule metabolic process GO:0055086 174 0.041
reactive oxygen species metabolic process GO:0072593 22 0.040
Human
cell projection assembly GO:0030031 94 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.040
regulation of phosphorylation GO:0042325 147 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.040
Human
positive regulation of cellular protein metabolic process GO:0032270 118 0.040
Human Mouse
positive regulation of intracellular signal transduction GO:1902533 116 0.039
Human Mouse
regulation of cell cycle process GO:0010564 181 0.039
negative regulation of cell death GO:0060548 81 0.039
Human Mouse
positive regulation of molecular function GO:0044093 136 0.038
Human
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.038
Human
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.038
electron transport chain GO:0022900 14 0.038
tube development GO:0035295 244 0.038
cytoskeleton dependent intracellular transport GO:0030705 44 0.037
negative regulation of protein metabolic process GO:0051248 85 0.037
Human
membrane fusion GO:0061025 42 0.037
sperm individualization GO:0007291 48 0.037
cell cycle arrest GO:0007050 4 0.037
endocytosis GO:0006897 310 0.036
Worm
hematopoietic or lymphoid organ development GO:0048534 57 0.036
response to inorganic substance GO:0010035 44 0.035
response to superoxide GO:0000303 3 0.035
glycosyl compound catabolic process GO:1901658 112 0.035
regulation of developmental growth GO:0048638 174 0.035
regulation of mitochondrial membrane potential GO:0051881 2 0.035
vesicle mediated transport GO:0016192 381 0.034
Worm
dendrite development GO:0016358 204 0.034
response to oxygen containing compound GO:1901700 200 0.033
modification dependent protein catabolic process GO:0019941 78 0.033
modification dependent macromolecule catabolic process GO:0043632 79 0.033
regulation of programmed cell death GO:0043067 152 0.033
Human Mouse
anion homeostasis GO:0055081 3 0.033
cellular amine metabolic process GO:0044106 12 0.032
cellular macromolecular complex assembly GO:0034622 153 0.032
regulation of reactive oxygen species metabolic process GO:2000377 8 0.032
Human
aromatic amino acid family metabolic process GO:0009072 3 0.032
aromatic compound catabolic process GO:0019439 166 0.031
nucleoside catabolic process GO:0009164 112 0.031
phospholipid homeostasis GO:0055091 1 0.031
cellular amino acid metabolic process GO:0006520 61 0.031
cuticle development GO:0042335 86 0.031
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.031
Human Mouse
regulation of neuron death GO:1901214 26 0.030
Human Mouse
protein transport GO:0015031 155 0.030
extrinsic apoptotic signaling pathway GO:0097191 1 0.030
anatomical structure homeostasis GO:0060249 97 0.030
cellular cation homeostasis GO:0030003 38 0.030
regulation of peptidase activity GO:0052547 39 0.030
response to nitrogen compound GO:1901698 90 0.029
intracellular protein transport GO:0006886 104 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.029
Human
cardiovascular system development GO:0072358 82 0.029
defense response GO:0006952 300 0.029
phosphorylation GO:0016310 294 0.029
negative regulation of molecular function GO:0044092 51 0.029
Human
skin development GO:0043588 65 0.028
axonogenesis GO:0007409 290 0.028
immune system process GO:0002376 347 0.028
anterior posterior axis specification embryo GO:0008595 103 0.027
columnar cuboidal epithelial cell development GO:0002066 249 0.027
nucleotide catabolic process GO:0009166 109 0.027
tripartite regional subdivision GO:0007351 103 0.027
cellular response to nutrient levels GO:0031669 62 0.027
regulation of secretion GO:0051046 44 0.026
Human Mouse
organophosphate catabolic process GO:0046434 112 0.026
cellular response to starvation GO:0009267 61 0.025
circulatory system process GO:0003013 37 0.025
stem cell proliferation GO:0072089 88 0.025
compound eye development GO:0048749 307 0.025
hemopoiesis GO:0030097 46 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.025
Human
negative regulation of cell cycle process GO:0010948 109 0.025
divalent inorganic cation homeostasis GO:0072507 29 0.025
positive regulation of transport GO:0051050 92 0.025
kidney development GO:0001822 3 0.025
negative regulation of wnt signaling pathway GO:0030178 28 0.024
negative regulation of reactive oxygen species metabolic process GO:2000378 1 0.024
Human
ion homeostasis GO:0050801 55 0.024
organonitrogen compound metabolic process GO:1901564 318 0.023
Mouse
post embryonic appendage morphogenesis GO:0035120 385 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
macroautophagy GO:0016236 42 0.023
wnt signaling pathway GO:0016055 98 0.023
developmental pigmentation GO:0048066 68 0.023
positive regulation of catalytic activity GO:0043085 118 0.023
regulation of synaptic transmission GO:0050804 69 0.023
Mouse
response to organic substance GO:0010033 284 0.022
Human
regulation of localization GO:0032879 275 0.022
Human Mouse Worm
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.022
Human
necrotic cell death GO:0070265 1 0.022
muscle structure development GO:0061061 224 0.022
axoneme assembly GO:0035082 18 0.022
response to bacterium GO:0009617 198 0.021
larval development GO:0002164 104 0.021
posttranscriptional regulation of gene expression GO:0010608 145 0.021
cellular macromolecule catabolic process GO:0044265 136 0.021
regulation of proteasomal protein catabolic process GO:0061136 39 0.021
Human Mouse
regulation of catalytic activity GO:0050790 185 0.021
Human
purine nucleotide catabolic process GO:0006195 109 0.020
positive regulation of transcription dna templated GO:0045893 266 0.020
Human
regulation of blood circulation GO:1903522 21 0.020
oocyte development GO:0048599 124 0.020
cation homeostasis GO:0055080 51 0.020
establishment of protein localization GO:0045184 163 0.020
axis specification GO:0009798 167 0.020
appendage morphogenesis GO:0035107 397 0.020
dendrite morphogenesis GO:0048813 199 0.020
positive regulation of cellular catabolic process GO:0031331 95 0.020
Human Mouse
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 14 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.020
Human Mouse
male courtship behavior veined wing generated song production GO:0045433 20 0.020
embryonic organ development GO:0048568 50 0.020
nucleotide metabolic process GO:0009117 161 0.020
positive regulation of secretion GO:0051047 22 0.020
regulation of nervous system development GO:0051960 248 0.020
protein localization to organelle GO:0033365 82 0.020
Mouse
regulation of system process GO:0044057 36 0.019
nucleoside monophosphate catabolic process GO:0009125 39 0.019
carbohydrate derivative catabolic process GO:1901136 118 0.019
border follicle cell migration GO:0007298 113 0.019
regulation of translation GO:0006417 56 0.019
apoptotic process GO:0006915 159 0.019
Human Mouse
circulatory system development GO:0072359 82 0.018
locomotor rhythm GO:0045475 56 0.018
negative regulation of phosphorus metabolic process GO:0010563 45 0.018
negative regulation of cellular component organization GO:0051129 108 0.018
regulation of protein ubiquitination GO:0031396 22 0.018
Human Mouse
cell death GO:0008219 279 0.018
Human Mouse
mitotic nuclear division GO:0007067 213 0.018
oocyte differentiation GO:0009994 145 0.018
gland development GO:0048732 191 0.018
cilium assembly GO:0042384 38 0.017
response to transforming growth factor beta GO:0071559 18 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
taxis GO:0042330 304 0.017
cellular response to endogenous stimulus GO:0071495 80 0.017
response to extracellular stimulus GO:0009991 116 0.016
chromatin organization GO:0006325 207 0.016
regulation of locomotion GO:0040012 42 0.016
Worm
response to radiation GO:0009314 155 0.016
ion transport GO:0006811 145 0.016
Mouse
protein catabolic process GO:0030163 101 0.016
positive regulation of cellular component organization GO:0051130 156 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.016
response to other organism GO:0051707 293 0.016
mitochondrial fission GO:0000266 8 0.016
chemotaxis GO:0006935 249 0.015
negative regulation of growth GO:0045926 84 0.015
response to temperature stimulus GO:0009266 106 0.015
response to alcohol GO:0097305 95 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.015
Human Mouse
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
multicellular organismal aging GO:0010259 140 0.015
Worm
heart process GO:0003015 37 0.015
regulation of protein phosphorylation GO:0001932 64 0.015
Human
regulation of cell division GO:0051302 72 0.015
regulation of developmental pigmentation GO:0048070 24 0.015
neuron projection guidance GO:0097485 241 0.015
regulation of epithelial cell proliferation GO:0050678 4 0.015
acylglycerol homeostasis GO:0055090 19 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
cellular response to hydrogen peroxide GO:0070301 7 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
translation GO:0006412 69 0.014
regulation of insulin receptor signaling pathway GO:0046626 17 0.014
regulation of membrane potential GO:0042391 35 0.014
immune system development GO:0002520 57 0.014
negative regulation of apoptotic process GO:0043066 63 0.014
Human Mouse
cellular protein catabolic process GO:0044257 83 0.014
atp biosynthetic process GO:0006754 2 0.013
determination of adult lifespan GO:0008340 137 0.013
Worm
cellular response to oxygen containing compound GO:1901701 79 0.013
single organism catabolic process GO:0044712 228 0.013
cell growth GO:0016049 108 0.013
renal system development GO:0072001 72 0.013
cytoskeleton dependent cytokinesis GO:0061640 81 0.013
cellular response to nitrogen compound GO:1901699 51 0.013
regulation of notch signaling pathway GO:0008593 100 0.013
secretion GO:0046903 109 0.013
Human Mouse
ribonucleoside monophosphate metabolic process GO:0009161 51 0.013
ovarian follicle cell stalk formation GO:0030713 17 0.013
organelle fusion GO:0048284 46 0.013
appendage development GO:0048736 401 0.013
neuron neuron synaptic transmission GO:0007270 14 0.013
Mouse
regulation of neuron projection development GO:0010975 69 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
neuron apoptotic process GO:0051402 17 0.013
Human Mouse
regulation of wnt signaling pathway GO:0030111 68 0.013
regulation of autophagy GO:0010506 62 0.013
Human
tyrosine metabolic process GO:0006570 1 0.013
negative regulation of phosphorylation GO:0042326 35 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
Human
positive regulation of protein transport GO:0051222 37 0.012
axon extension GO:0048675 32 0.012
cellular response to oxygen levels GO:0071453 30 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.012
atp synthesis coupled electron transport GO:0042773 8 0.012
neuromuscular synaptic transmission GO:0007274 67 0.012
cellular response to decreased oxygen levels GO:0036294 30 0.012
oxoacid metabolic process GO:0043436 103 0.012
negative regulation of mitochondrion organization GO:0010823 2 0.012
aging GO:0007568 143 0.012
Worm
regulation of cellular ketone metabolic process GO:0010565 3 0.012
phagocytosis GO:0006909 215 0.012
Worm
oocyte construction GO:0007308 112 0.012
dna metabolic process GO:0006259 227 0.012
regulation of cytoskeleton organization GO:0051493 89 0.011
Human
cellular response to organonitrogen compound GO:0071417 36 0.011
epidermis development GO:0008544 65 0.011
stem cell division GO:0017145 69 0.011
cellular response to oxidative stress GO:0034599 28 0.011
embryonic morphogenesis GO:0048598 206 0.011
ribonucleoside biosynthetic process GO:0042455 3 0.011
digestive system development GO:0055123 149 0.011
synaptic transmission GO:0007268 288 0.011
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
camera type eye morphogenesis GO:0048593 2 0.011
response to copper ion GO:0046688 4 0.011
autophagy GO:0006914 108 0.011
sperm mitochondrion organization GO:0030382 7 0.011
positive regulation of protein modification process GO:0031401 58 0.010
Human Mouse
epidermal cell differentiation GO:0009913 51 0.010
organic acid metabolic process GO:0006082 103 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
Worm
positive regulation of cell development GO:0010720 61 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
cytoplasmic transport GO:0016482 130 0.010
response to glucose GO:0009749 2 0.010
regulation of phosphatase activity GO:0010921 3 0.010
regulation of intracellular transport GO:0032386 64 0.010
wing disc morphogenesis GO:0007472 344 0.010

park disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
parkinson s disease DOID:14330 0 0.659
Human
synucleinopathy DOID:0050890 0 0.659
Human
central nervous system disease DOID:331 0 0.659
Human
disease of anatomical entity DOID:7 0 0.659
Human
neurodegenerative disease DOID:1289 0 0.659
Human
nervous system disease DOID:863 0 0.659
Human
retinal disease DOID:5679 0 0.028
retinal degeneration DOID:8466 0 0.028
sensory system disease DOID:0050155 0 0.028
macular degeneration DOID:4448 0 0.028
eye and adnexa disease DOID:1492 0 0.028
eye disease DOID:5614 0 0.028
disease of metabolism DOID:0014667 0 0.021
cancer DOID:162 0 0.015
Human
disease of cellular proliferation DOID:14566 0 0.015
Human