Drosophila melanogaster

124 known processes

sim (Dmel_CG7771)

single-minded

(Aliases: S8,1111/10,1110/04,l(3)S8,1050/13,Sim,l(3)RD,1479/04,Dmel\CG7771,0716/08,0483/09,0953/08,1034/02,CG7771,SIM,1330/08,1002/10,bHLHe16,schm,0899/14,l(3)87Ea,l(3)s8,shm,l(3)E320)

sim biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 201 0.970
tissue morphogenesis GO:0048729 297 0.892
adult behavior GO:0030534 137 0.883
taxis GO:0042330 304 0.878
negative regulation of cellular metabolic process GO:0031324 382 0.871
Mouse
morphogenesis of an epithelium GO:0002009 276 0.855
embryonic morphogenesis GO:0048598 206 0.853
cell migration GO:0016477 238 0.843
Fly
neuron projection guidance GO:0097485 241 0.826
embryonic pattern specification GO:0009880 174 0.802
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.792
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.769
Mouse
cell motility GO:0048870 251 0.739
Fly
negative regulation of biosynthetic process GO:0009890 277 0.702
Mouse
stem cell differentiation GO:0048863 117 0.660
regulation of dendrite development GO:0050773 37 0.659
segmentation GO:0035282 207 0.649
death GO:0016265 284 0.624
gland development GO:0048732 191 0.611
multi organism behavior GO:0051705 175 0.581
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.579
reproductive behavior GO:0019098 122 0.575
axon development GO:0061564 297 0.561
outflow tract morphogenesis GO:0003151 4 0.552
epithelial cell development GO:0002064 274 0.548
eye photoreceptor cell development GO:0042462 81 0.542
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.538
Mouse
eye photoreceptor cell differentiation GO:0001754 145 0.533
negative regulation of rna metabolic process GO:0051253 251 0.489
Mouse
positive regulation of rna metabolic process GO:0051254 271 0.473
head development GO:0060322 135 0.470
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.458
Mouse
locomotory behavior GO:0007626 176 0.457
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.457
columnar cuboidal epithelial cell development GO:0002066 249 0.442
positive regulation of transcription dna templated GO:0045893 266 0.436
response to organic substance GO:0010033 284 0.436
Fly
border follicle cell migration GO:0007298 113 0.422
negative regulation of gene expression GO:0010629 387 0.414
Mouse
chemotaxis GO:0006935 249 0.401
single organism behavior GO:0044708 391 0.391
neurological system process GO:0050877 358 0.388
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.388
anterior posterior pattern specification GO:0009952 136 0.387
programmed cell death GO:0012501 257 0.385
epithelial cell differentiation GO:0030855 322 0.383
kidney development GO:0001822 3 0.380
Mouse
axon guidance GO:0007411 233 0.377
tube morphogenesis GO:0035239 191 0.374
motor neuron axon guidance GO:0008045 58 0.372
regionalization GO:0003002 416 0.367
epithelial cell migration GO:0010631 148 0.356
chemosensory behavior GO:0007635 106 0.355
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.347
Mouse
cell fate determination GO:0001709 91 0.338
negative regulation of developmental process GO:0051093 201 0.336
exocrine system development GO:0035272 162 0.334
response to oxygen containing compound GO:1901700 200 0.329
Fly
localization of cell GO:0051674 257 0.319
Fly
multi organism reproductive behavior GO:0044705 121 0.318
positive regulation of rna biosynthetic process GO:1902680 266 0.312
blastoderm segmentation GO:0007350 159 0.306
regulation of cell development GO:0060284 215 0.302
olfactory behavior GO:0042048 97 0.300
positive regulation of macromolecule metabolic process GO:0010604 405 0.294
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.289
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.288
reproductive system development GO:0061458 74 0.280
ovarian follicle cell development GO:0030707 248 0.272
positive regulation of biosynthetic process GO:0009891 316 0.269
morphogenesis of embryonic epithelium GO:0016331 94 0.269
positive regulation of nucleic acid templated transcription GO:1903508 266 0.268
negative regulation of transcription dna templated GO:0045892 237 0.267
Mouse
neuron fate commitment GO:0048663 50 0.260
axonogenesis GO:0007409 290 0.259
behavioral response to ethanol GO:0048149 49 0.252
regulation of cell differentiation GO:0045595 302 0.252
torso signaling pathway GO:0008293 21 0.249
dendrite guidance GO:0070983 21 0.246
courtship behavior GO:0007619 68 0.244
glial cell migration GO:0008347 31 0.240
multicellular organismal reproductive behavior GO:0033057 110 0.239
response to bacterium GO:0009617 198 0.237
embryo development ending in birth or egg hatching GO:0009792 152 0.234
neuron fate specification GO:0048665 12 0.234
tripartite regional subdivision GO:0007351 103 0.233
muscle cell differentiation GO:0042692 103 0.229
embryonic development via the syncytial blastoderm GO:0001700 148 0.227
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.227
Mouse
telencephalon development GO:0021537 2 0.226
transcription from rna polymerase ii promoter GO:0006366 368 0.219
muscle organ development GO:0007517 127 0.214
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.208
response to alcohol GO:0097305 95 0.207
organic hydroxy compound metabolic process GO:1901615 83 0.204
feeding behavior GO:0007631 50 0.204
photoreceptor cell differentiation GO:0046530 170 0.195
anterior posterior axis specification embryo GO:0008595 103 0.189
salivary gland morphogenesis GO:0007435 145 0.189
anterior posterior axis specification GO:0009948 109 0.189
regulation of nervous system development GO:0051960 248 0.188
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.176
lipid metabolic process GO:0006629 121 0.174
ventral cord development GO:0007419 16 0.171
inter male aggressive behavior GO:0002121 60 0.165
respiratory system development GO:0060541 213 0.162
Mouse Fly
regulation of growth GO:0040008 233 0.162
Fly
cell division GO:0051301 248 0.161
ovarian follicle cell migration GO:0007297 121 0.160
adult locomotory behavior GO:0008344 76 0.159
mating behavior GO:0007617 106 0.158
regulation of behavior GO:0050795 75 0.155
response to monosaccharide GO:0034284 4 0.154
cell death GO:0008219 279 0.153
developmental growth GO:0048589 280 0.149
cuticle development GO:0042335 86 0.149
heart development GO:0007507 82 0.147
camera type eye development GO:0043010 4 0.142
regulation of protein metabolic process GO:0051246 256 0.140
dorsal ventral axon guidance GO:0033563 2 0.140
development of primary sexual characteristics GO:0045137 50 0.137
renal system development GO:0072001 72 0.137
Mouse
reproductive structure development GO:0048608 74 0.136
negative regulation of cell differentiation GO:0045596 143 0.136
photoreceptor cell development GO:0042461 96 0.133
positive regulation of cell development GO:0010720 61 0.133
regulation of apoptotic process GO:0042981 130 0.132
dorsal closure GO:0007391 79 0.128
multi multicellular organism process GO:0044706 123 0.128
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.125
regulation of programmed cell death GO:0043067 152 0.125
negative regulation of multicellular organismal process GO:0051241 142 0.124
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.123
camera type eye photoreceptor cell differentiation GO:0060219 2 0.122
renal tubule development GO:0061326 64 0.121
digestive tract development GO:0048565 149 0.121
positive regulation of gene expression GO:0010628 290 0.121
negative regulation of cellular biosynthetic process GO:0031327 277 0.120
Mouse
regulation of localization GO:0032879 275 0.113
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.113
kidney epithelium development GO:0072073 3 0.113
Mouse
embryonic hemopoiesis GO:0035162 26 0.112
digestive tract morphogenesis GO:0048546 127 0.111
substrate dependent cell migration GO:0006929 3 0.111
immune system process GO:0002376 347 0.111
response to glucose GO:0009749 2 0.109
positive regulation of axonogenesis GO:0050772 2 0.107
epithelial tube morphogenesis GO:0060562 88 0.107
myotube differentiation GO:0014902 46 0.105
regulation of epithelial cell proliferation GO:0050678 4 0.104
neuroblast division GO:0055057 35 0.103
camera type eye morphogenesis GO:0048593 2 0.103
mesenchymal cell differentiation GO:0048762 1 0.103
muscle structure development GO:0061061 224 0.102
epithelium migration GO:0090132 148 0.101
cognition GO:0050890 141 0.100
chemical homeostasis GO:0048878 92 0.099
regulation of hormone levels GO:0010817 40 0.099
mating GO:0007618 120 0.098
negative regulation of cell communication GO:0010648 223 0.097
imaginal disc derived appendage development GO:0048737 399 0.097
axis specification GO:0009798 167 0.097
regulation of multicellular organismal development GO:2000026 414 0.096
associative learning GO:0008306 65 0.095
central nervous system neuron differentiation GO:0021953 8 0.095
photoreceptor cell fate commitment GO:0046552 41 0.092
male courtship behavior GO:0008049 63 0.091
regulation of cell death GO:0010941 173 0.091
embryonic axis specification GO:0000578 107 0.089
gliogenesis GO:0042063 80 0.089
epithelial cell proliferation GO:0050673 15 0.087
negative regulation of nervous system development GO:0051961 92 0.087
regulation of r7 cell differentiation GO:0045676 15 0.086
gastrulation GO:0007369 70 0.086
negative regulation of neurogenesis GO:0050768 53 0.086
cardiovascular system development GO:0072358 82 0.085
negative regulation of signaling GO:0023057 219 0.085
regulation of neurogenesis GO:0050767 158 0.084
cell fate specification GO:0001708 71 0.084
dendrite morphogenesis GO:0048813 199 0.084
cardioblast cell fate specification GO:0042685 9 0.083
ion homeostasis GO:0050801 55 0.083
positive regulation of neurogenesis GO:0050769 41 0.081
wound healing GO:0042060 75 0.080
tube development GO:0035295 244 0.080
Mouse
positive regulation of nervous system development GO:0051962 69 0.080
compound eye photoreceptor development GO:0042051 78 0.078
response to wounding GO:0009611 94 0.078
regulation of neuron differentiation GO:0045664 103 0.076
stem cell fate commitment GO:0048865 25 0.075
appendage development GO:0048736 401 0.075
embryonic organ development GO:0048568 50 0.074
cellular response to chemical stimulus GO:0070887 199 0.074
Fly
eye photoreceptor cell fate commitment GO:0042706 37 0.074
positive regulation of developmental process GO:0051094 143 0.073
single organism cellular localization GO:1902580 180 0.073
steroid biosynthetic process GO:0006694 16 0.073
protein complex biogenesis GO:0070271 201 0.073
spinal cord development GO:0021510 1 0.072
hindbrain development GO:0030902 2 0.072
response to lipopolysaccharide GO:0032496 4 0.072
mesenchyme development GO:0060485 9 0.072
imaginal disc derived appendage morphogenesis GO:0035114 395 0.071
cardioblast cell fate commitment GO:0042684 14 0.070
immune system development GO:0002520 57 0.067
positive regulation of programmed cell death GO:0043068 62 0.066
protein transport GO:0015031 155 0.065
positive regulation of cell differentiation GO:0045597 64 0.065
response to hexose GO:0009746 3 0.065
defense response GO:0006952 300 0.064
gonad development GO:0008406 50 0.064
single organism biosynthetic process GO:0044711 206 0.064
negative regulation of response to stimulus GO:0048585 258 0.064
male gamete generation GO:0048232 201 0.063
genitalia development GO:0048806 26 0.062
establishment of localization in cell GO:0051649 402 0.062
determination of digestive tract left right asymmetry GO:0071907 6 0.062
neuroblast fate determination GO:0007400 12 0.062
negative regulation of cell development GO:0010721 62 0.062
protein complex assembly GO:0006461 200 0.061
salivary gland development GO:0007431 162 0.059
stem cell development GO:0048864 79 0.058
apoptotic process involved in morphogenesis GO:0060561 3 0.058
nephron morphogenesis GO:0072028 3 0.057
asymmetric cell division GO:0008356 37 0.057
heart morphogenesis GO:0003007 32 0.057
microtubule based movement GO:0007018 51 0.056
phenol containing compound metabolic process GO:0018958 57 0.055
positive regulation of apoptotic process GO:0043065 47 0.055
retinal cone cell differentiation GO:0042670 2 0.055
blood circulation GO:0008015 26 0.054
single organism cell adhesion GO:0098602 47 0.054
cell maturation GO:0048469 144 0.054
retina development in camera type eye GO:0060041 4 0.054
negative regulation of cellular component organization GO:0051129 108 0.054
organic substance transport GO:0071702 257 0.053
neuroblast fate commitment GO:0014017 19 0.053
compound eye photoreceptor cell differentiation GO:0001751 140 0.053
dendrite development GO:0016358 204 0.053
immune response GO:0006955 246 0.052
apoptotic process GO:0006915 159 0.052
imaginal disc derived female genitalia development GO:0007486 6 0.052
terminal region determination GO:0007362 25 0.051
epithelial cell migration open tracheal system GO:0007427 32 0.051
secretion by cell GO:0032940 101 0.050
compound eye development GO:0048749 307 0.050
lipid biosynthetic process GO:0008610 46 0.050
regulation of anatomical structure morphogenesis GO:0022603 242 0.050
hematopoietic or lymphoid organ development GO:0048534 57 0.049
imaginal disc derived wing morphogenesis GO:0007476 337 0.049
skeletal muscle organ development GO:0060538 48 0.048
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.048
anatomical structure homeostasis GO:0060249 97 0.048
pole plasm oskar mrna localization GO:0045451 46 0.047
actin filament based process GO:0030029 220 0.046
cardioblast differentiation GO:0010002 20 0.044
forebrain development GO:0030900 2 0.043
Zebrafish
pole plasm mrna localization GO:0019094 49 0.043
oocyte development GO:0048599 124 0.043
regulation of synapse structure and activity GO:0050803 128 0.043
spermatogenesis GO:0007283 200 0.042
tissue migration GO:0090130 155 0.042
larval development GO:0002164 104 0.042
endocytosis GO:0006897 310 0.042
brain development GO:0007420 120 0.042
regulation of cytoskeleton organization GO:0051493 89 0.041
regulation of photoreceptor cell differentiation GO:0046532 34 0.041
regulation of synapse assembly GO:0051963 94 0.041
small molecule biosynthetic process GO:0044283 37 0.041
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.041
oocyte anterior posterior axis specification GO:0007314 72 0.040
sex differentiation GO:0007548 81 0.040
digestive system development GO:0055123 149 0.040
female genitalia development GO:0030540 6 0.040
response to organonitrogen compound GO:0010243 75 0.040
Fly
developmental programmed cell death GO:0010623 138 0.040
rhythmic process GO:0048511 106 0.039
enzyme linked receptor protein signaling pathway GO:0007167 179 0.039
tissue death GO:0016271 102 0.039
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.038
head involution GO:0008258 35 0.038
ameboidal type cell migration GO:0001667 151 0.038
response to extracellular stimulus GO:0009991 116 0.038
regulation of reproductive process GO:2000241 54 0.037
r7 cell differentiation GO:0045466 43 0.037
neuroblast proliferation GO:0007405 74 0.037
regulation of cell projection organization GO:0031344 92 0.037
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.037
eye antennal disc morphogenesis GO:0007455 34 0.037
gonad morphogenesis GO:0035262 7 0.036
hematopoietic progenitor cell differentiation GO:0002244 1 0.036
sensory organ morphogenesis GO:0090596 260 0.036
lamellipodium assembly GO:0030032 21 0.036
gland morphogenesis GO:0022612 145 0.035
negative regulation of neuron differentiation GO:0045665 16 0.035
regulation of axon extension involved in axon guidance GO:0048841 4 0.035
regulation of neuron projection development GO:0010975 69 0.034
positive regulation of cellular component organization GO:0051130 156 0.034
connective tissue development GO:0061448 3 0.033
cell proliferation GO:0008283 299 0.033
cellular response to nutrient levels GO:0031669 62 0.033
regulation of dendrite morphogenesis GO:0048814 28 0.033
negative regulation of epithelial cell proliferation GO:0050680 4 0.032
positive regulation of cell death GO:0010942 69 0.032
circadian rhythm GO:0007623 105 0.032
positive regulation of multicellular organismal process GO:0051240 143 0.032
body morphogenesis GO:0010171 2 0.032
establishment of glial blood brain barrier GO:0060857 14 0.032
branching morphogenesis of an epithelial tube GO:0048754 45 0.031
cellular response to carbohydrate stimulus GO:0071322 4 0.031
cellular response to monosaccharide stimulus GO:0071326 2 0.031
cardiocyte differentiation GO:0035051 29 0.031
regulation of cellular component movement GO:0051270 42 0.031
Fly
sensory perception GO:0007600 196 0.031
negative regulation of programmed cell death GO:0043069 72 0.030
germarium derived egg chamber formation GO:0007293 101 0.030
nephron epithelium morphogenesis GO:0072088 3 0.030
cell growth GO:0016049 108 0.029
Fly
positive regulation of axon extension GO:0045773 2 0.029
positive regulation of autophagy GO:0010508 21 0.029
Fly
regulation of cell migration GO:0030334 22 0.029
Fly
oocyte differentiation GO:0009994 145 0.029
secretion GO:0046903 109 0.029
genital disc development GO:0035215 44 0.028
stem cell maintenance GO:0019827 67 0.028
nephron epithelium development GO:0072009 3 0.028
synaptic transmission GO:0007268 288 0.028
nephron tubule morphogenesis GO:0072078 3 0.028
homeostatic process GO:0042592 199 0.028
melanin metabolic process GO:0006582 47 0.028
cellular response to oxidative stress GO:0034599 28 0.028
cellular protein localization GO:0034613 160 0.028
central complex development GO:0048036 9 0.028
dorsal ventral pattern formation GO:0009953 133 0.028
hormone metabolic process GO:0042445 33 0.028
eye development GO:0001654 323 0.027
chitin based cuticle development GO:0040003 49 0.027
myoblast fusion GO:0007520 43 0.027
positive regulation of cell migration GO:0030335 2 0.027
cellular protein modification process GO:0006464 438 0.027
regulation of cardioblast differentiation GO:0051890 9 0.027
regulation of response to oxidative stress GO:1902882 4 0.027
establishment of organelle localization GO:0051656 122 0.027
organic hydroxy compound biosynthetic process GO:1901617 21 0.027
establishment or maintenance of cell polarity GO:0007163 167 0.027
macromolecular complex assembly GO:0065003 256 0.026
regulation of transport GO:0051049 181 0.026
urogenital system development GO:0001655 72 0.026
Mouse
intracellular protein transport GO:0006886 104 0.026
protein localization to organelle GO:0033365 82 0.026
protein localization GO:0008104 284 0.026
vesicle mediated transport GO:0016192 381 0.026
cellular response to hormone stimulus GO:0032870 44 0.026
Fly
organelle localization GO:0051640 148 0.025
mesenchymal cell development GO:0014031 1 0.025
cellular response to hexose stimulus GO:0071331 1 0.025
neuronal stem cell division GO:0036445 35 0.025
axon regeneration GO:0031103 8 0.025
axon midline choice point recognition GO:0016199 26 0.025
maintenance of location GO:0051235 73 0.025
response to biotic stimulus GO:0009607 294 0.024
small molecule metabolic process GO:0044281 305 0.024
cellular macromolecular complex assembly GO:0034622 153 0.024
stem cell division GO:0017145 69 0.024
stem cell proliferation GO:0072089 88 0.024
regulation of endopeptidase activity GO:0052548 36 0.024
gonadal mesoderm development GO:0007506 8 0.024
response to oxidative stress GO:0006979 86 0.024
cell fate specification involved in pattern specification GO:0060573 8 0.024
response to endogenous stimulus GO:0009719 119 0.023
Fly
intracellular transport GO:0046907 228 0.023
positive regulation of developmental growth GO:0048639 62 0.023
neuron recognition GO:0008038 101 0.023
positive regulation of transport GO:0051050 92 0.023
syncytium formation GO:0006949 43 0.023
protein modification process GO:0036211 438 0.023
circulatory system development GO:0072359 82 0.023
ketone biosynthetic process GO:0042181 16 0.023
protein modification by small protein conjugation GO:0032446 79 0.023
dorsal appendage formation GO:0046843 47 0.023
regulation of smoothened signaling pathway GO:0008589 28 0.023
histolysis GO:0007559 102 0.023
chromosome organization GO:0051276 360 0.023
regulation of proteolysis GO:0030162 87 0.022
aggressive behavior GO:0002118 63 0.022
epithelial tube formation GO:0072175 7 0.022
hormone biosynthetic process GO:0042446 20 0.022
response to hormone GO:0009725 45 0.022
Fly
cell migration involved in gastrulation GO:0042074 9 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.021
regulation of autophagy GO:0010506 62 0.021
Fly
cellular response to nitrogen compound GO:1901699 51 0.021
Fly
epidermis development GO:0008544 65 0.021
cellular chemical homeostasis GO:0055082 40 0.021
cellular response to oxygen containing compound GO:1901701 79 0.021
Fly
central nervous system projection neuron axonogenesis GO:0021952 6 0.021
muscle tissue morphogenesis GO:0060415 2 0.021
mesodermal cell fate specification GO:0007501 2 0.021
renal tubule morphogenesis GO:0061333 44 0.021
regulation of cell proliferation GO:0042127 163 0.021
microtubule based transport GO:0010970 42 0.021
regulation of cell fate commitment GO:0010453 29 0.021
appendage morphogenesis GO:0035107 397 0.021
developmental pigmentation GO:0048066 68 0.021
negative regulation of cell proliferation GO:0008285 69 0.021
heart process GO:0003015 37 0.020
positive regulation of axon guidance GO:1902669 1 0.020
hemopoiesis GO:0030097 46 0.020
developmental maturation GO:0021700 172 0.020
retinal ganglion cell axon guidance GO:0031290 12 0.020
open tracheal system development GO:0007424 204 0.020
regulation of microtubule based process GO:0032886 49 0.020
compound eye cone cell fate commitment GO:0042676 5 0.020
negative regulation of axon extension GO:0030517 3 0.020
wing disc morphogenesis GO:0007472 344 0.020
negative regulation of phosphorus metabolic process GO:0010563 45 0.020
pole plasm assembly GO:0007315 61 0.020
proteolysis GO:0006508 192 0.020
female sex differentiation GO:0046660 20 0.020
eggshell formation GO:0030703 105 0.020
negative regulation of cell death GO:0060548 81 0.020
learning or memory GO:0007611 141 0.019
regulation of cell morphogenesis GO:0022604 163 0.019
heart formation GO:0060914 6 0.019
neuroblast development GO:0014019 13 0.019
positive regulation of signaling GO:0023056 243 0.019
segment polarity determination GO:0007367 25 0.019
limb morphogenesis GO:0035108 1 0.019
visual perception GO:0007601 9 0.019
retina morphogenesis in camera type eye GO:0060042 2 0.019
single organismal cell cell adhesion GO:0016337 45 0.019
muscle fiber development GO:0048747 12 0.019
axon extension involved in axon guidance GO:0048846 10 0.019
epidermal cell differentiation GO:0009913 51 0.019
glial cell fate commitment GO:0021781 3 0.019
phagocytosis GO:0006909 215 0.019
regulation of developmental growth GO:0048638 174 0.018
cellular response to endogenous stimulus GO:0071495 80 0.018
Fly
response to temperature stimulus GO:0009266 106 0.018
imaginal disc derived leg segmentation GO:0036011 26 0.018
regulation of epithelial cell differentiation GO:0030856 4 0.018
ventral midline development GO:0007418 9 0.018
morphogenesis of a branching epithelium GO:0061138 45 0.018
regulation of axon guidance GO:1902667 10 0.018
compound eye morphogenesis GO:0001745 249 0.018
stem cell fate determination GO:0048867 15 0.018
morphogenesis of follicular epithelium GO:0016333 36 0.018
learning GO:0007612 75 0.018
cellular response to external stimulus GO:0071496 66 0.018
regulation of multicellular organism growth GO:0040014 40 0.017
response to insulin GO:0032868 29 0.017
Fly
cell adhesion GO:0007155 136 0.017
protein modification by small protein conjugation or removal GO:0070647 106 0.017
regulation of protein localization GO:0032880 76 0.017
multicellular organism growth GO:0035264 46 0.017
positive regulation of growth GO:0045927 75 0.017
photoreceptor cell axon guidance GO:0072499 23 0.017
metal ion homeostasis GO:0055065 44 0.017
positive regulation of organ growth GO:0046622 12 0.017
innate immune response GO:0045087 144 0.017
response to other organism GO:0051707 293 0.017
cellular response to organonitrogen compound GO:0071417 36 0.017
Fly
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.017
establishment of protein localization GO:0045184 163 0.017
organ formation GO:0048645 39 0.017
neuroblast differentiation GO:0014016 29 0.017
mesoderm development GO:0007498 78 0.017
regulation of hydrolase activity GO:0051336 97 0.017
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.016
regulation of cell motility GO:2000145 23 0.016
Fly
detection of stimulus involved in sensory perception GO:0050906 92 0.016
carbohydrate metabolic process GO:0005975 82 0.016
regulation of blood circulation GO:1903522 21 0.016
anterior commissure morphogenesis GO:0021960 2 0.016
mitochondrion organization GO:0007005 65 0.016
immune effector process GO:0002252 98 0.016
negative regulation of synapse assembly GO:0051964 39 0.016
nuclear import GO:0051170 51 0.016
hindgut development GO:0061525 58 0.016
protein polymerization GO:0051258 42 0.016
regulation of response to external stimulus GO:0032101 115 0.016
regulation of neuroblast proliferation GO:1902692 34 0.016
regulation of synaptic transmission GO:0050804 69 0.015
kidney morphogenesis GO:0060993 3 0.015
dna metabolic process GO:0006259 227 0.015
positive regulation of neuron differentiation GO:0045666 26 0.015
periodic partitioning GO:0007365 29 0.015
negative regulation of signal transduction GO:0009968 206 0.015

sim disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.230
nervous system disease DOID:863 0 0.047
cancer DOID:162 0 0.031
disease of cellular proliferation DOID:14566 0 0.031
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.020
eye disease DOID:5614 0 0.020
urinary system disease DOID:18 0 0.019