Drosophila melanogaster

36 known processes

fs(2)ltoPP43 (Dmel_CG10528)

female sterile (2) ltoPP43

(Aliases: LD12957,Dmel\CG10528,l(2)38Ac,BEST:LD12957,CG10528)

fs(2)ltoPP43 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 143 0.264
chromosome organization GO:0051276 360 0.247
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.247
histone modification GO:0016570 106 0.182
chromatin organization GO:0006325 207 0.173
positive regulation of nucleic acid templated transcription GO:1903508 266 0.166
cellular response to dna damage stimulus GO:0006974 223 0.162
multicellular organismal aging GO:0010259 140 0.151
transcription from rna polymerase ii promoter GO:0006366 368 0.149
determination of adult lifespan GO:0008340 137 0.149
negative regulation of transcription dna templated GO:0045892 237 0.143
positive regulation of peptidase activity GO:0010952 29 0.141
positive regulation of rna metabolic process GO:0051254 271 0.135
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.122
positive regulation of proteolysis GO:0045862 52 0.122
regulation of cell death GO:0010941 173 0.121
response to oxidative stress GO:0006979 86 0.114
dna metabolic process GO:0006259 227 0.102
mitotic dna integrity checkpoint GO:0044774 75 0.101
intracellular signal transduction GO:0035556 300 0.101
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.094
positive regulation of response to stimulus GO:0048584 323 0.083
protein modification process GO:0036211 438 0.078
positive regulation of biosynthetic process GO:0009891 316 0.078
regulation of response to stress GO:0080134 200 0.077
regulation of cysteine type endopeptidase activity GO:2000116 27 0.074
positive regulation of macromolecule metabolic process GO:0010604 405 0.073
chromatin modification GO:0016568 147 0.071
neurological system process GO:0050877 358 0.071
positive regulation of transcription dna templated GO:0045893 266 0.070
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.069
regulation of apoptotic process GO:0042981 130 0.069
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.067
covalent chromatin modification GO:0016569 106 0.065
peptidyl lysine acetylation GO:0018394 39 0.064
regulation of cell cycle process GO:0010564 181 0.062
positive regulation of rna biosynthetic process GO:1902680 266 0.062
reproductive behavior GO:0019098 122 0.062
regulation of proteolysis GO:0030162 87 0.061
negative regulation of nucleic acid templated transcription GO:1903507 240 0.060
regulation of epithelial cell proliferation GO:0050678 4 0.059
g2 dna damage checkpoint GO:0031572 69 0.057
negative regulation of gene expression GO:0010629 387 0.057
immune system process GO:0002376 347 0.057
proteolysis GO:0006508 192 0.056
imaginal disc derived appendage development GO:0048737 399 0.056
camera type eye development GO:0043010 4 0.055
regulation of immune system process GO:0002682 176 0.055
positive regulation of programmed cell death GO:0043068 62 0.055
double strand break repair GO:0006302 26 0.054
dna templated transcription initiation GO:0006352 25 0.052
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.052
positive regulation of apoptotic process GO:0043065 47 0.051
regulation of cellular ketone metabolic process GO:0010565 3 0.050
positive regulation of cell death GO:0010942 69 0.050
embryo development ending in birth or egg hatching GO:0009792 152 0.050
negative regulation of rna biosynthetic process GO:1902679 240 0.049
protein transport GO:0015031 155 0.049
negative regulation of cellular biosynthetic process GO:0031327 277 0.047
negative regulation of programmed cell death GO:0043069 72 0.047
regulation of multi organism process GO:0043900 131 0.046
regulation of cell differentiation GO:0045595 302 0.045
regulation of programmed cell death GO:0043067 152 0.045
growth GO:0040007 359 0.044
positive regulation of apoptotic signaling pathway GO:2001235 4 0.044
enzyme linked receptor protein signaling pathway GO:0007167 179 0.043
positive regulation of cellular biosynthetic process GO:0031328 316 0.043
negative regulation of signaling GO:0023057 219 0.042
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.041
eye development GO:0001654 323 0.041
apoptotic process GO:0006915 159 0.039
mrna splicing via spliceosome GO:0000398 73 0.039
regulation of anatomical structure morphogenesis GO:0022603 242 0.038
macromolecular complex assembly GO:0065003 256 0.038
programmed cell death GO:0012501 257 0.038
response to endogenous stimulus GO:0009719 119 0.038
cell cell signaling involved in cell fate commitment GO:0045168 210 0.037
regulation of multicellular organismal development GO:2000026 414 0.037
negative regulation of cellular metabolic process GO:0031324 382 0.036
negative regulation of intracellular signal transduction GO:1902532 57 0.036
regulation of growth GO:0040008 233 0.035
regulation of cell cycle phase transition GO:1901987 130 0.035
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.034
negative regulation of signal transduction GO:0009968 206 0.034
defense response GO:0006952 300 0.033
negative regulation of apoptotic process GO:0043066 63 0.033
dna conformation change GO:0071103 105 0.033
cell proliferation GO:0008283 299 0.032
stem cell division GO:0017145 69 0.032
wing disc morphogenesis GO:0007472 344 0.031
protein dna complex subunit organization GO:0071824 86 0.031
response to radiation GO:0009314 155 0.031
intrinsic apoptotic signaling pathway GO:0097193 16 0.031
internal peptidyl lysine acetylation GO:0018393 38 0.031
regulation of endopeptidase activity GO:0052548 36 0.030
axonogenesis GO:0007409 290 0.030
cellular response to oxidative stress GO:0034599 28 0.030
negative regulation of cell communication GO:0010648 223 0.030
response to other organism GO:0051707 293 0.030
mitochondrion organization GO:0007005 65 0.030
compound eye development GO:0048749 307 0.029
regulation of intracellular signal transduction GO:1902531 236 0.029
regulation of meiosis GO:0040020 3 0.029
cellular protein modification process GO:0006464 438 0.029
mitotic g2 dna damage checkpoint GO:0007095 69 0.029
cellular response to growth factor stimulus GO:0071363 30 0.029
negative regulation of cell death GO:0060548 81 0.029
immune effector process GO:0002252 98 0.028
regulation of peptidase activity GO:0052547 39 0.028
negative regulation of biosynthetic process GO:0009890 277 0.028
nuclear division GO:0000280 332 0.028
regulation of developmental growth GO:0048638 174 0.028
cellular macromolecular complex assembly GO:0034622 153 0.028
dna recombination GO:0006310 32 0.027
regulation of cell cycle GO:0051726 291 0.027
positive regulation of cell communication GO:0010647 250 0.027
positive regulation of signaling GO:0023056 243 0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.027
positive regulation of gene expression GO:0010628 290 0.026
nucleosome organization GO:0034728 59 0.026
response to uv GO:0009411 24 0.026
protein complex assembly GO:0006461 200 0.026
mrna metabolic process GO:0016071 124 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.026
regulation of transcription by chromatin organization GO:0034401 3 0.026
chromatin remodeling GO:0006338 72 0.026
mitotic spindle organization GO:0007052 220 0.026
rna splicing GO:0008380 83 0.026
regionalization GO:0003002 416 0.026
signal transduction in response to dna damage GO:0042770 3 0.025
regulation of cell cycle g1 s phase transition GO:1902806 23 0.025
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.025
peptidyl lysine modification GO:0018205 57 0.024
regulation of protein metabolic process GO:0051246 256 0.024
cell cycle phase transition GO:0044770 140 0.024
developmental growth GO:0048589 280 0.024
positive regulation of signal transduction GO:0009967 223 0.024
negative regulation of growth GO:0045926 84 0.024
protein localization GO:0008104 284 0.024
histone acetylation GO:0016573 38 0.023
appendage development GO:0048736 401 0.023
regulation of intracellular transport GO:0032386 64 0.023
negative regulation of neuron death GO:1901215 18 0.023
chromatin assembly or disassembly GO:0006333 52 0.023
intracellular transport GO:0046907 228 0.023
dna repair GO:0006281 54 0.022
cellular response to radiation GO:0071478 52 0.022
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.022
positive regulation of protein metabolic process GO:0051247 128 0.022
embryonic morphogenesis GO:0048598 206 0.022
imaginal disc derived wing morphogenesis GO:0007476 337 0.022
extrinsic apoptotic signaling pathway GO:0097191 1 0.022
cellular macromolecule localization GO:0070727 220 0.022
tissue morphogenesis GO:0048729 297 0.021
positive regulation of developmental process GO:0051094 143 0.021
jak stat cascade GO:0007259 49 0.021
death GO:0016265 284 0.021
central nervous system development GO:0007417 201 0.021
regulation of cellular response to stress GO:0080135 89 0.021
response to bacterium GO:0009617 198 0.020
positive regulation of endopeptidase activity GO:0010950 26 0.020
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.020
cell type specific apoptotic process GO:0097285 38 0.020
protein acetylation GO:0006473 39 0.020
positive regulation of growth GO:0045927 75 0.020
cell division GO:0051301 248 0.020
spindle organization GO:0007051 253 0.020
gonad development GO:0008406 50 0.020
protein ubiquitination GO:0016567 70 0.019
locomotory behavior GO:0007626 176 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.019
establishment of localization in cell GO:0051649 402 0.019
negative regulation of response to stimulus GO:0048585 258 0.019
bmp signaling pathway GO:0030509 27 0.019
wound healing GO:0042060 75 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.019
single organism intracellular transport GO:1902582 207 0.019
defense response to other organism GO:0098542 225 0.018
dna replication GO:0006260 48 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.018
regulation of cellular response to oxidative stress GO:1900407 4 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.017
rhythmic process GO:0048511 106 0.017
organelle fission GO:0048285 340 0.017
regulation of nervous system development GO:0051960 248 0.017
hemocyte differentiation GO:0042386 38 0.017
regulation of response to oxidative stress GO:1902882 4 0.017
cellular protein localization GO:0034613 160 0.017
post embryonic appendage morphogenesis GO:0035120 385 0.017
regulation of mitotic cell cycle GO:0007346 190 0.017
meiotic dna double strand break formation GO:0042138 1 0.017
lateral inhibition GO:0046331 206 0.016
phagocytosis GO:0006909 215 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
positive regulation of cell cycle process GO:0090068 28 0.016
male gamete generation GO:0048232 201 0.016
amine metabolic process GO:0009308 12 0.015
peptidyl threonine phosphorylation GO:0018107 2 0.015
internal protein amino acid acetylation GO:0006475 38 0.015
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.015
cellular ketone metabolic process GO:0042180 24 0.015
rna processing GO:0006396 147 0.015
positive regulation of mitotic cell cycle GO:0045931 34 0.015
negative regulation of molecular function GO:0044092 51 0.015
response to organic substance GO:0010033 284 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
axon development GO:0061564 297 0.015
negative regulation of phosphorylation GO:0042326 35 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
regulation of cell development GO:0060284 215 0.015
macromolecule catabolic process GO:0009057 161 0.014
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.014
mapk cascade GO:0000165 107 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.014
protein complex biogenesis GO:0070271 201 0.014
negative regulation of developmental process GO:0051093 201 0.014
histone h3 acetylation GO:0043966 11 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.014
spindle assembly involved in mitosis GO:0090307 50 0.014
protein acylation GO:0043543 42 0.014
phosphorylation GO:0016310 294 0.014
multi organism behavior GO:0051705 175 0.014
negative regulation of response to oxidative stress GO:1902883 1 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
cytoplasmic transport GO:0016482 130 0.013
homeostatic process GO:0042592 199 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
developmental maturation GO:0021700 172 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
mrna processing GO:0006397 104 0.013
dna integrity checkpoint GO:0031570 81 0.013
mitotic sister chromatid segregation GO:0000070 87 0.013
establishment of protein localization GO:0045184 163 0.013
vesicle mediated transport GO:0016192 381 0.013
response to abiotic stimulus GO:0009628 341 0.013
cell aging GO:0007569 2 0.013
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.013
carbohydrate derivative biosynthetic process GO:1901137 85 0.013
meiosis i GO:0007127 59 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
regulation of nucleocytoplasmic transport GO:0046822 35 0.013
n glycan processing GO:0006491 3 0.013
stem cell differentiation GO:0048863 117 0.013
chromosome segregation GO:0007059 157 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
positive regulation of lipid metabolic process GO:0045834 4 0.013
negative regulation of neurogenesis GO:0050768 53 0.012
response to light stimulus GO:0009416 124 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
immune response GO:0006955 246 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.012
cell cycle g1 s phase transition GO:0044843 31 0.012
chemotaxis GO:0006935 249 0.012
intracellular protein transport GO:0006886 104 0.012
regulation of synaptic transmission GO:0050804 69 0.012
cellular amine metabolic process GO:0044106 12 0.012
protein dna complex assembly GO:0065004 63 0.012
neuron projection guidance GO:0097485 241 0.012
dna damage checkpoint GO:0000077 78 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.012
retina development in camera type eye GO:0060041 4 0.012
regulation of hydrolase activity GO:0051336 97 0.012
negative regulation of cell cycle GO:0045786 116 0.012
mitotic nuclear division GO:0007067 213 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
respiratory system development GO:0060541 213 0.012
response to transforming growth factor beta GO:0071559 18 0.012
cell death GO:0008219 279 0.012
meiotic cell cycle process GO:1903046 132 0.012
nitrogen compound transport GO:0071705 85 0.012
regulation of cell proliferation GO:0042127 163 0.012
regulation of response to extracellular stimulus GO:0032104 18 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
regulation of defense response GO:0031347 102 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
eye morphogenesis GO:0048592 260 0.012
axon guidance GO:0007411 233 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
nuclear transport GO:0051169 72 0.011
negative regulation of gene expression epigenetic GO:0045814 77 0.011
organic substance transport GO:0071702 257 0.011
positive regulation of developmental growth GO:0048639 62 0.011
cellular protein catabolic process GO:0044257 83 0.011
protein phosphorylation GO:0006468 169 0.011
small molecule metabolic process GO:0044281 305 0.011
regulation of protein transport GO:0051223 57 0.011
negative regulation of developmental growth GO:0048640 64 0.011
negative regulation of epithelial cell proliferation GO:0050680 4 0.011
protein catabolic process GO:0030163 101 0.011
epithelial cell proliferation GO:0050673 15 0.011
mitotic cell cycle embryonic GO:0045448 38 0.011
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of catalytic activity GO:0050790 185 0.011
cell cycle arrest GO:0007050 4 0.010
dna packaging GO:0006323 91 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
oxoacid metabolic process GO:0043436 103 0.010
single organism biosynthetic process GO:0044711 206 0.010
response to biotic stimulus GO:0009607 294 0.010
negative regulation of nervous system development GO:0051961 92 0.010
regulation of dna metabolic process GO:0051052 34 0.010
organic acid metabolic process GO:0006082 103 0.010
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.010
regulation of cellular component biogenesis GO:0044087 201 0.010
protein maturation GO:0051604 71 0.010
nucleobase containing compound transport GO:0015931 56 0.010
gland development GO:0048732 191 0.010
circulatory system development GO:0072359 82 0.010

fs(2)ltoPP43 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.012