Drosophila melanogaster

21 known processes

Toll-6 (Dmel_CG7250)

CG7250 gene product from transcript CG7250-RA

(Aliases: Tl-6,dTLR6,dToll6,toll-6,18w-like,CT22359,toll,CG7250,TOLL 6,Dmel\CG7250)

Toll-6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
maintenance of gastrointestinal epithelium GO:0030277 3 0.727
Mouse
activation of innate immune response GO:0002218 4 0.584
Human Mouse
positive regulation of nf kappab import into nucleus GO:0042346 1 0.491
Human
immune response regulating signaling pathway GO:0002764 2 0.404
Human Mouse
immune response activating signal transduction GO:0002757 2 0.360
Human Mouse
innate immune response activating signal transduction GO:0002758 2 0.347
Human Mouse
regulation of nf kappab import into nucleus GO:0042345 1 0.283
Human
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.281
Human Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.269
Human Mouse
pattern recognition receptor signaling pathway GO:0002221 2 0.263
Human Mouse
post embryonic appendage morphogenesis GO:0035120 385 0.243
regulation of localization GO:0032879 275 0.240
Human
regulation of intracellular signal transduction GO:1902531 236 0.224
Human Mouse
positive regulation of rna metabolic process GO:0051254 271 0.220
Mouse
regulation of protein metabolic process GO:0051246 256 0.211
Human Mouse
death GO:0016265 284 0.210
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.210
Mouse
organic substance transport GO:0071702 257 0.205
Human
positive regulation of gene expression GO:0010628 290 0.202
Mouse
intracellular signal transduction GO:0035556 300 0.201
Human Mouse
defense response to virus GO:0051607 23 0.196
Human Mouse Fly
extrinsic apoptotic signaling pathway GO:0097191 1 0.193
Human
response to organic substance GO:0010033 284 0.191
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.190
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.189
Mouse
regulation of autophagy GO:0010506 62 0.186
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.185
Human Mouse
appendage morphogenesis GO:0035107 397 0.179
response to dsrna GO:0043331 15 0.178
Human Mouse
regulation of response to wounding GO:1903034 19 0.177
Mouse
positive regulation of signaling GO:0023056 243 0.177
Human Mouse
positive regulation of biosynthetic process GO:0009891 316 0.176
Human Mouse
regulation of defense response to virus GO:0050688 14 0.168
Fly
regulation of innate immune response GO:0045088 71 0.168
Human Mouse
cell death GO:0008219 279 0.164
Human
transcription from rna polymerase ii promoter GO:0006366 368 0.163
Mouse
regulation of transport GO:0051049 181 0.163
Human
cellular catabolic process GO:0044248 372 0.160
Fly
nf kappab import into nucleus GO:0042348 1 0.153
Human
cellular protein modification process GO:0006464 438 0.152
Human
epithelial structure maintenance GO:0010669 17 0.151
Mouse
positive regulation of transcription factor import into nucleus GO:0042993 19 0.147
Human
regulation of multi organism process GO:0043900 131 0.147
Fly
response to mechanical stimulus GO:0009612 28 0.146
Human
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.143
Human Mouse
phosphorylation GO:0016310 294 0.141
Human Mouse
adult behavior GO:0030534 137 0.139
regulation of immune response GO:0050776 118 0.136
Human Mouse
positive regulation of molecular function GO:0044093 136 0.133
Mouse
protein transport GO:0015031 155 0.132
Human
regulation of defense response GO:0031347 102 0.132
Human Mouse Fly
programmed cell death GO:0012501 257 0.131
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.130
Mouse
cellular response to chemical stimulus GO:0070887 199 0.128
positive regulation of immune response GO:0050778 63 0.127
Human Mouse
dendrite development GO:0016358 204 0.126
positive regulation of defense response GO:0031349 59 0.126
Human Mouse
eye morphogenesis GO:0048592 260 0.126
cellular response to external stimulus GO:0071496 66 0.122
Human
establishment of localization in cell GO:0051649 402 0.122
Human
protein phosphorylation GO:0006468 169 0.120
Human
negative regulation of multicellular organismal process GO:0051241 142 0.119
Mouse
developmental programmed cell death GO:0010623 138 0.118
regulation of multicellular organismal development GO:2000026 414 0.117
regulation of nervous system development GO:0051960 248 0.116
protein targeting to nucleus GO:0044744 51 0.115
Human
imaginal disc derived appendage morphogenesis GO:0035114 395 0.115
positive regulation of protein transport GO:0051222 37 0.113
Human
positive regulation of response to stimulus GO:0048584 323 0.112
Human Mouse
positive regulation of cell communication GO:0010647 250 0.109
Human Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.108
Mouse
regulation of response to biotic stimulus GO:0002831 63 0.108
Fly
immune response GO:0006955 246 0.106
Mouse
response to abiotic stimulus GO:0009628 341 0.105
Human
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.105
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.105
Mouse
catabolic process GO:0009056 409 0.104
Fly
intracellular protein transport GO:0006886 104 0.102
Human
regulation of cellular localization GO:0060341 136 0.102
Human
response to external biotic stimulus GO:0043207 293 0.102
Human Mouse Fly
organonitrogen compound metabolic process GO:1901564 318 0.101
positive regulation of protein localization to nucleus GO:1900182 21 0.101
Human
single organism cellular localization GO:1902580 180 0.100
Human
protein localization GO:0008104 284 0.099
Human
homeostatic process GO:0042592 199 0.099
Mouse
regulation of response to stress GO:0080134 200 0.099
Human Mouse Fly
growth GO:0040007 359 0.099
positive regulation of developmental process GO:0051094 143 0.097
immune effector process GO:0002252 98 0.094
Human Mouse Fly
positive regulation of protein import into nucleus GO:0042307 21 0.092
Human
positive regulation of transport GO:0051050 92 0.092
Human
apoptotic process GO:0006915 159 0.091
Human
regulation of catabolic process GO:0009894 170 0.090
Fly
apoptotic signaling pathway GO:0097190 27 0.090
Human
regulation of protein transport GO:0051223 57 0.090
Human
cellular response to extracellular stimulus GO:0031668 64 0.088
positive regulation of transcription dna templated GO:0045893 266 0.088
Mouse
intracellular transport GO:0046907 228 0.088
Human
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.086
regulation of intracellular protein transport GO:0033157 46 0.086
Human
developmental growth GO:0048589 280 0.086
positive regulation of autophagy GO:0010508 21 0.085
Fly
regulation of growth GO:0040008 233 0.084
regulation of immune system process GO:0002682 176 0.084
Human Mouse Fly
wing disc morphogenesis GO:0007472 344 0.083
protein localization to nucleus GO:0034504 55 0.082
Human
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.081
Human
regulation of cellular catabolic process GO:0031329 157 0.080
Fly
single organism intracellular transport GO:1902582 207 0.079
Human
protein modification process GO:0036211 438 0.079
Human
positive regulation of cell development GO:0010720 61 0.079
cellular macromolecule localization GO:0070727 220 0.077
Human
sensory organ morphogenesis GO:0090596 260 0.077
locomotory behavior GO:0007626 176 0.076
regulation of intracellular transport GO:0032386 64 0.075
Human
cellular response to organic substance GO:0071310 132 0.071
positive regulation of peptidase activity GO:0010952 29 0.070
tissue morphogenesis GO:0048729 297 0.070
negative regulation of biosynthetic process GO:0009890 277 0.070
anatomical structure homeostasis GO:0060249 97 0.070
Mouse
necrotic cell death GO:0070265 1 0.069
Human
protein complex localization GO:0031503 4 0.068
Human
response to growth factor GO:0070848 31 0.068
hippo signaling GO:0035329 20 0.068
regulation of protein localization GO:0032880 76 0.067
Human
positive regulation of signal transduction GO:0009967 223 0.067
Human Mouse
spermatogenesis GO:0007283 200 0.067
nuclear import GO:0051170 51 0.067
Human
epithelial cell differentiation GO:0030855 322 0.067
regulation of catalytic activity GO:0050790 185 0.067
single organism nuclear import GO:1902593 51 0.066
Human
synapse assembly GO:0007416 143 0.066
appendage development GO:0048736 401 0.065
response to other organism GO:0051707 293 0.065
Human Mouse Fly
regulation of cell differentiation GO:0045595 302 0.065
regulation of developmental growth GO:0048638 174 0.064
male gamete generation GO:0048232 201 0.064
regulation of molecular function GO:0065009 217 0.064
Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.063
Human Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.063
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.063
muscle structure development GO:0061061 224 0.062
regulation of immune effector process GO:0002697 52 0.062
Fly
dendrite morphogenesis GO:0048813 199 0.062
negative regulation of cellular metabolic process GO:0031324 382 0.062
defense response GO:0006952 300 0.060
Human Mouse Fly
regulation of establishment of protein localization GO:0070201 61 0.060
Human
response to bacterium GO:0009617 198 0.059
regulation of programmed cell death GO:0043067 152 0.059
immune system process GO:0002376 347 0.058
Human Mouse Fly
brain development GO:0007420 120 0.057
tissue homeostasis GO:0001894 36 0.056
Mouse
head development GO:0060322 135 0.056
cytoplasmic transport GO:0016482 130 0.055
Human
synapse organization GO:0050808 196 0.055
digestive tract morphogenesis GO:0048546 127 0.055
biological adhesion GO:0022610 138 0.055
compound eye morphogenesis GO:0001745 249 0.054
nitrogen compound transport GO:0071705 85 0.053
Human
hemocyte differentiation GO:0042386 38 0.052
regulation of cell development GO:0060284 215 0.052
cell division GO:0051301 248 0.052
negative regulation of gene expression GO:0010629 387 0.051
establishment of protein localization GO:0045184 163 0.051
Human
proteolysis GO:0006508 192 0.051
defense response to other organism GO:0098542 225 0.051
Human Mouse Fly
cell maturation GO:0048469 144 0.050
regulation of nucleocytoplasmic transport GO:0046822 35 0.050
Human
cellular response to abiotic stimulus GO:0071214 58 0.049
Human
positive regulation of immune system process GO:0002684 68 0.049
Human Mouse
positive regulation of programmed cell death GO:0043068 62 0.049
lateral inhibition GO:0046331 206 0.048
protein localization to organelle GO:0033365 82 0.047
Human
imaginal disc derived appendage development GO:0048737 399 0.047
enzyme linked receptor protein signaling pathway GO:0007167 179 0.046
positive regulation of intracellular signal transduction GO:1902533 116 0.046
Human Mouse
neuron projection guidance GO:0097485 241 0.046
negative regulation of apoptotic process GO:0043066 63 0.046
regulation of hemocyte differentiation GO:0045610 22 0.045
body morphogenesis GO:0010171 2 0.045
regulation of epithelial cell proliferation GO:0050678 4 0.045
regionalization GO:0003002 416 0.045
positive regulation of innate immune response GO:0045089 38 0.044
Human Mouse
tube morphogenesis GO:0035239 191 0.044
camera type eye development GO:0043010 4 0.043
response to organic cyclic compound GO:0014070 89 0.043
Human Mouse
activation of immune response GO:0002253 5 0.043
Human Mouse
positive regulation of multi organism process GO:0043902 40 0.041
i kappab phosphorylation GO:0007252 3 0.041
Human
imaginal disc derived wing morphogenesis GO:0007476 337 0.041
dorsal ventral pattern formation GO:0009953 133 0.041
regulation of phosphorus metabolic process GO:0051174 210 0.040
Mouse
regulation of epithelial cell differentiation GO:0030856 4 0.040
retinal cell programmed cell death GO:0046666 25 0.040
regulation of cellular amino acid metabolic process GO:0006521 0 0.040
axonogenesis GO:0007409 290 0.040
single organism behavior GO:0044708 391 0.040
response to glucose GO:0009749 2 0.039
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.039
regulation of organ growth GO:0046620 42 0.039
regulation of mapk cascade GO:0043408 92 0.039
Mouse
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.039
innate immune response GO:0045087 144 0.039
Mouse
response to biotic stimulus GO:0009607 294 0.039
Human Mouse Fly
regulation of response to external stimulus GO:0032101 115 0.039
Mouse Fly
neurological system process GO:0050877 358 0.039
cellular protein localization GO:0034613 160 0.039
Human
positive regulation of cellular catabolic process GO:0031331 95 0.038
Fly
mitotic cytokinesis GO:0000281 50 0.038
negative regulation of nucleic acid templated transcription GO:1903507 240 0.038
positive regulation of catabolic process GO:0009896 105 0.038
Fly
regulation of protein import into nucleus GO:0042306 28 0.037
Human
protein targeting GO:0006605 64 0.037
Human
eye development GO:0001654 323 0.037
positive regulation of nervous system development GO:0051962 69 0.037
regulation of cell death GO:0010941 173 0.037
carbohydrate derivative biosynthetic process GO:1901137 85 0.037
spermatid differentiation GO:0048515 114 0.036
macromolecular complex assembly GO:0065003 256 0.036
jnk cascade GO:0007254 50 0.036
Mouse
forebrain development GO:0030900 2 0.036
detection of stimulus involved in sensory perception GO:0050906 92 0.036
establishment of protein localization to organelle GO:0072594 62 0.035
Human
carbohydrate derivative metabolic process GO:1901135 217 0.035
neuron recognition GO:0008038 101 0.035
tube development GO:0035295 244 0.035
compound eye development GO:0048749 307 0.035
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.034
positive regulation of neurogenesis GO:0050769 41 0.034
regulation of protein localization to nucleus GO:1900180 29 0.033
Human
compound eye photoreceptor fate commitment GO:0001752 36 0.033
regulation of phosphate metabolic process GO:0019220 210 0.033
Mouse
sensory perception GO:0007600 196 0.033
nucleobase containing compound catabolic process GO:0034655 165 0.033
regulation of neurogenesis GO:0050767 158 0.032
negative regulation of transcription dna templated GO:0045892 237 0.032
positive regulation of cell death GO:0010942 69 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.032
single organism carbohydrate metabolic process GO:0044723 72 0.031
mapk cascade GO:0000165 107 0.031
Mouse
response to hexose GO:0009746 3 0.031
regulation of cellular protein metabolic process GO:0032268 243 0.031
spermatid development GO:0007286 98 0.031
kidney morphogenesis GO:0060993 3 0.029
renal tubule morphogenesis GO:0061333 44 0.029
establishment of planar polarity GO:0001736 87 0.029
cell proliferation GO:0008283 299 0.029
response to virus GO:0009615 28 0.029
Human Mouse Fly
positive regulation of apoptotic process GO:0043065 47 0.029
negative regulation of cellular biosynthetic process GO:0031327 277 0.029
limb development GO:0060173 1 0.028
regulation of apoptotic process GO:0042981 130 0.028
negative regulation of rna metabolic process GO:0051253 251 0.028
organic substance catabolic process GO:1901575 308 0.028
kidney development GO:0001822 3 0.028
regulation of neuron differentiation GO:0045664 103 0.028
positive regulation of intracellular protein transport GO:0090316 30 0.027
Human
renal tubule development GO:0061326 64 0.027
camera type eye morphogenesis GO:0048593 2 0.027
response to starvation GO:0042594 97 0.027
vesicle mediated transport GO:0016192 381 0.027
regulation of cell cycle GO:0051726 291 0.027
regulation of synaptic transmission GO:0050804 69 0.027
taxis GO:0042330 304 0.026
negative regulation of response to stimulus GO:0048585 258 0.026
secretion GO:0046903 109 0.026
regulation of transcription factor import into nucleus GO:0042990 22 0.026
Human
regulation of peptide transport GO:0090087 7 0.026
Human
cell adhesion GO:0007155 136 0.026
epidermal cell differentiation GO:0009913 51 0.026
actin filament organization GO:0007015 126 0.026
regulation of cell proliferation GO:0042127 163 0.026
phagocytosis GO:0006909 215 0.025
regulation of gene silencing GO:0060968 63 0.025
imaginal disc pattern formation GO:0007447 91 0.025
signal transduction by phosphorylation GO:0023014 107 0.025
Mouse
regulation of cell fate commitment GO:0010453 29 0.024
cellular nitrogen compound catabolic process GO:0044270 165 0.024
negative regulation of signaling GO:0023057 219 0.024
establishment or maintenance of cell polarity GO:0007163 167 0.024
negative regulation of cell fate specification GO:0009996 15 0.024
positive regulation of catalytic activity GO:0043085 118 0.024
gland morphogenesis GO:0022612 145 0.024
small molecule metabolic process GO:0044281 305 0.024
nuclear transport GO:0051169 72 0.023
Human
developmental maturation GO:0021700 172 0.023
cell cell signaling involved in cell fate commitment GO:0045168 210 0.023
response to oxygen containing compound GO:1901700 200 0.023
peptide transport GO:0015833 10 0.023
Human
gliogenesis GO:0042063 80 0.023
antimicrobial peptide production GO:0002775 46 0.023
response to wounding GO:0009611 94 0.023
Mouse
ribonucleoside catabolic process GO:0042454 112 0.023
syncytium formation by plasma membrane fusion GO:0000768 43 0.023
eye photoreceptor cell differentiation GO:0001754 145 0.023
endocytosis GO:0006897 310 0.023
regulation of peptidase activity GO:0052547 39 0.023
regulation of hydrolase activity GO:0051336 97 0.022
telencephalon development GO:0021537 2 0.022
positive regulation of phosphate metabolic process GO:0045937 139 0.022
Mouse
multi organism behavior GO:0051705 175 0.022
negative regulation of rna biosynthetic process GO:1902679 240 0.022
morphogenesis of a polarized epithelium GO:0001738 93 0.022
regulation of cytoplasmic transport GO:1903649 47 0.022
Human
defense response to bacterium GO:0042742 178 0.022
glycoprotein metabolic process GO:0009100 41 0.022
antimicrobial humoral response GO:0019730 99 0.022
negative regulation of nervous system development GO:0051961 92 0.022
carbohydrate metabolic process GO:0005975 82 0.022
retina development in camera type eye GO:0060041 4 0.022
negative regulation of cell death GO:0060548 81 0.022
axis specification GO:0009798 167 0.022
positive regulation of protein metabolic process GO:0051247 128 0.022
Human Mouse
behavioral response to ethanol GO:0048149 49 0.021
embryonic morphogenesis GO:0048598 206 0.021
regulation of antimicrobial humoral response GO:0002759 50 0.021
positive regulation of proteolysis GO:0045862 52 0.021
sensory perception of mechanical stimulus GO:0050954 72 0.021
cell migration GO:0016477 238 0.021
secretion by cell GO:0032940 101 0.021
synaptic growth at neuromuscular junction GO:0051124 119 0.021
localization of cell GO:0051674 257 0.021
nucleoside catabolic process GO:0009164 112 0.021
neuron maturation GO:0042551 31 0.021
regulation of cell morphogenesis GO:0022604 163 0.021
nephron morphogenesis GO:0072028 3 0.021
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.021
neuroblast differentiation GO:0014016 29 0.021
organ growth GO:0035265 56 0.021
regulation of organelle organization GO:0033043 196 0.021
nephron tubule morphogenesis GO:0072078 3 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
positive regulation of cell cycle GO:0045787 43 0.020
salivary gland morphogenesis GO:0007435 145 0.020
regulation of protein modification process GO:0031399 112 0.020
autophagy GO:0006914 108 0.020
Fly
chemotaxis GO:0006935 249 0.020
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.020
photoreceptor cell differentiation GO:0046530 170 0.020
positive regulation of endopeptidase activity GO:0010950 26 0.019
regulation of cellular response to stress GO:0080135 89 0.019
Mouse
lipid metabolic process GO:0006629 121 0.019
cranial nerve development GO:0021545 1 0.019
epithelial cell development GO:0002064 274 0.019
organelle fission GO:0048285 340 0.019
regulation of endopeptidase activity GO:0052548 36 0.019
cell cycle arrest GO:0007050 4 0.019
cytokinesis GO:0000910 90 0.019
amide biosynthetic process GO:0043604 42 0.019
cellular response to nutrient levels GO:0031669 62 0.019
central nervous system development GO:0007417 201 0.019
positive regulation of retinal cell programmed cell death GO:0046670 9 0.019
respiratory system development GO:0060541 213 0.019
regulation of secretion by cell GO:1903530 39 0.019
purine nucleotide catabolic process GO:0006195 109 0.019
regulation of organ morphogenesis GO:2000027 78 0.019
regulation of cell division GO:0051302 72 0.019
smoothened signaling pathway GO:0007224 49 0.019
regulation of protein targeting GO:1903533 29 0.018
Human
single organism catabolic process GO:0044712 228 0.018
regulation of synapse organization GO:0050807 110 0.018
organophosphate metabolic process GO:0019637 195 0.018
notch signaling pathway GO:0007219 120 0.018
negative regulation of cell cycle GO:0045786 116 0.018
stress activated mapk cascade GO:0051403 52 0.018
Mouse
cellular response to mechanical stimulus GO:0071260 2 0.018
Human
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.018
stress activated protein kinase signaling cascade GO:0031098 55 0.018
Mouse
compound eye photoreceptor cell differentiation GO:0001751 140 0.018
regulation of cysteine type endopeptidase activity GO:2000116 27 0.018
positive regulation of cell differentiation GO:0045597 64 0.018
positive regulation of cell motility GO:2000147 3 0.018
positive regulation of hydrolase activity GO:0051345 78 0.018
positive regulation of response to biotic stimulus GO:0002833 31 0.018
response to monosaccharide GO:0034284 4 0.018
positive regulation of cell migration GO:0030335 2 0.017
regulation of axon extension involved in axon guidance GO:0048841 4 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.017
regulation of wnt signaling pathway GO:0030111 68 0.017
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.017
limb morphogenesis GO:0035108 1 0.017
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.017
dna packaging GO:0006323 91 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
cell activation GO:0001775 9 0.017
Mouse
hindgut development GO:0061525 58 0.017
cell motility GO:0048870 251 0.017
embryonic development via the syncytial blastoderm GO:0001700 148 0.017
connective tissue development GO:0061448 3 0.017
open tracheal system development GO:0007424 204 0.017
cellular response to hexose stimulus GO:0071331 1 0.017
muscle organ development GO:0007517 127 0.017
hindgut morphogenesis GO:0007442 58 0.017
cell type specific apoptotic process GO:0097285 38 0.017
locomotor rhythm GO:0045475 56 0.017
establishment of tissue polarity GO:0007164 87 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
spinal cord development GO:0021510 1 0.016
sensory organ boundary specification GO:0008052 22 0.016
organ or tissue specific immune response GO:0002251 10 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
exocrine system development GO:0035272 162 0.016
cellular component assembly involved in morphogenesis GO:0010927 151 0.016
mucosal immune response GO:0002385 10 0.016
malpighian tubule morphogenesis GO:0007443 44 0.016
rhythmic process GO:0048511 106 0.016
cellular response to starvation GO:0009267 61 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
negative regulation of developmental process GO:0051093 201 0.016
epithelial tube morphogenesis GO:0060562 88 0.016
actin cytoskeleton organization GO:0030036 206 0.015
dorsal ventral axis specification GO:0009950 66 0.015
somatic muscle development GO:0007525 66 0.015
regulation of cell cycle process GO:0010564 181 0.015
mesoderm morphogenesis GO:0048332 22 0.015
embryo development ending in birth or egg hatching GO:0009792 152 0.015
regulation of cytoskeleton organization GO:0051493 89 0.015
regulation of photoreceptor cell differentiation GO:0046532 34 0.015
compound eye retinal cell programmed cell death GO:0046667 23 0.015
dna metabolic process GO:0006259 227 0.015
dna damage checkpoint GO:0000077 78 0.015
regulation of phosphorylation GO:0042325 147 0.015
Mouse
amide transport GO:0042886 10 0.015
Human
signal transduction in response to dna damage GO:0042770 3 0.015
salivary gland histolysis GO:0035070 88 0.015
synaptic target recognition GO:0008039 45 0.015
response to ionizing radiation GO:0010212 32 0.015
cellular homeostasis GO:0019725 80 0.015
cell fate specification GO:0001708 71 0.015
nucleocytoplasmic transport GO:0006913 72 0.015
Human
neuropeptide signaling pathway GO:0007218 45 0.015
cellular response to endogenous stimulus GO:0071495 80 0.015
actin filament based process GO:0030029 220 0.015
response to endogenous stimulus GO:0009719 119 0.015
heterocycle catabolic process GO:0046700 166 0.015
neuromuscular junction development GO:0007528 149 0.015
mitochondrion organization GO:0007005 65 0.014
striated muscle cell differentiation GO:0051146 90 0.014
neural retina development GO:0003407 4 0.014
negative regulation of signal transduction GO:0009968 206 0.014
muscle cell development GO:0055001 50 0.014
protein complex biogenesis GO:0070271 201 0.014
regulation of cell projection organization GO:0031344 92 0.014
urogenital system development GO:0001655 72 0.014
humoral immune response GO:0006959 117 0.014
asymmetric cell division GO:0008356 37 0.014
amine metabolic process GO:0009308 12 0.014
protein glycosylation GO:0006486 32 0.014
mesenchymal cell development GO:0014031 1 0.014
chromosome organization GO:0051276 360 0.014
olfactory behavior GO:0042048 97 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
cell cycle checkpoint GO:0000075 95 0.014
positive regulation of secretion GO:0051047 22 0.014
regulation of notch signaling pathway GO:0008593 100 0.014
digestive tract development GO:0048565 149 0.014
cellular protein catabolic process GO:0044257 83 0.014
digestive system development GO:0055123 149 0.014
aromatic compound catabolic process GO:0019439 166 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
segmentation GO:0035282 207 0.014
circadian behavior GO:0048512 76 0.014
signal release GO:0023061 49 0.014
eye photoreceptor cell fate commitment GO:0042706 37 0.014
antimicrobial peptide biosynthetic process GO:0002777 38 0.014
protein ubiquitination GO:0016567 70 0.014
protein processing GO:0016485 68 0.014
adult locomotory behavior GO:0008344 76 0.014
positive regulation of antimicrobial humoral response GO:0002760 28 0.013
cellular amine metabolic process GO:0044106 12 0.013
cellular response to monosaccharide stimulus GO:0071326 2 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
regulation of proteolysis GO:0030162 87 0.013
regulation of secretion GO:0051046 44 0.013
regulation of neuron apoptotic process GO:0043523 16 0.013
hair cell differentiation GO:0035315 47 0.013
striated muscle cell development GO:0055002 50 0.013
chemosensory behavior GO:0007635 106 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
regulation of neuroblast proliferation GO:1902692 34 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
neuron apoptotic process GO:0051402 17 0.013
protein import into nucleus GO:0006606 51 0.013
Human
negative regulation of cell cycle process GO:0010948 109 0.013

Toll-6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
nervous system disease DOID:863 0 0.025
sensory system disease DOID:0050155 0 0.017
cardiovascular system disease DOID:1287 0 0.016
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
organ system cancer DOID:0050686 0 0.013