Drosophila melanogaster

7 known processes

ApepP (Dmel_CG6291)

Aminopeptidase P

(Aliases: AP-P,Daminopep-p,DAP-P,CG6291,Dmel\CG6291)

ApepP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule metabolic process GO:0044281 305 0.262
negative regulation of cellular biosynthetic process GO:0031327 277 0.216
single organism catabolic process GO:0044712 228 0.190
regulation of cell cycle process GO:0010564 181 0.168
cell cycle phase transition GO:0044770 140 0.166
compound eye development GO:0048749 307 0.140
cellular response to dna damage stimulus GO:0006974 223 0.132
homeostatic process GO:0042592 199 0.126
cellular lipid metabolic process GO:0044255 83 0.117
negative regulation of cell cycle process GO:0010948 109 0.115
organophosphate metabolic process GO:0019637 195 0.113
vesicle mediated transport GO:0016192 381 0.111
mitotic dna damage checkpoint GO:0044773 74 0.105
regulation of cell cycle GO:0051726 291 0.104
organic substance catabolic process GO:1901575 308 0.103
Human
carbohydrate derivative metabolic process GO:1901135 217 0.098
lipid metabolic process GO:0006629 121 0.097
nucleotide catabolic process GO:0009166 109 0.097
nucleobase containing compound catabolic process GO:0034655 165 0.095
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.092
embryonic morphogenesis GO:0048598 206 0.091
regulation of cell cycle phase transition GO:1901987 130 0.090
purine nucleotide catabolic process GO:0006195 109 0.086
oxoacid metabolic process GO:0043436 103 0.085
regulation of mitotic cell cycle GO:0007346 190 0.082
spermatogenesis GO:0007283 200 0.081
cellular catabolic process GO:0044248 372 0.080
Human
regulation of mitotic cell cycle phase transition GO:1901990 130 0.080
organonitrogen compound metabolic process GO:1901564 318 0.079
Human
purine ribonucleotide metabolic process GO:0009150 145 0.079
catabolic process GO:0009056 409 0.076
Human
purine nucleoside metabolic process GO:0042278 127 0.075
mitotic cell cycle phase transition GO:0044772 138 0.072
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.072
intracellular signal transduction GO:0035556 300 0.070
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.069
negative regulation of biosynthetic process GO:0009890 277 0.068
purine containing compound metabolic process GO:0072521 155 0.067
posttranscriptional regulation of gene expression GO:0010608 145 0.066
negative regulation of cell cycle GO:0045786 116 0.066
cell division GO:0051301 248 0.065
sensory organ morphogenesis GO:0090596 260 0.065
glycosyl compound metabolic process GO:1901657 127 0.063
heterocycle catabolic process GO:0046700 166 0.063
g2 dna damage checkpoint GO:0031572 69 0.063
glycosyl compound catabolic process GO:1901658 112 0.062
purine ribonucleoside metabolic process GO:0046128 127 0.061
cellular nitrogen compound catabolic process GO:0044270 165 0.061
nucleoside metabolic process GO:0009116 127 0.060
sulfur compound metabolic process GO:0006790 59 0.060
aromatic compound catabolic process GO:0019439 166 0.059
negative regulation of cellular metabolic process GO:0031324 382 0.059
nucleobase containing small molecule metabolic process GO:0055086 174 0.059
macromolecular complex assembly GO:0065003 256 0.058
mitotic g2 dna damage checkpoint GO:0007095 69 0.058
negative regulation of gene expression GO:0010629 387 0.057
mitotic cell cycle checkpoint GO:0007093 88 0.057
organic acid metabolic process GO:0006082 103 0.057
purine ribonucleoside catabolic process GO:0046130 112 0.056
ribonucleoside catabolic process GO:0042454 112 0.055
growth GO:0040007 359 0.055
nitrogen compound transport GO:0071705 85 0.054
nucleoside triphosphate metabolic process GO:0009141 120 0.054
mitotic g2 m transition checkpoint GO:0044818 70 0.053
purine nucleoside triphosphate catabolic process GO:0009146 108 0.052
protein modification process GO:0036211 438 0.050
ribonucleotide metabolic process GO:0009259 145 0.050
cellular protein modification process GO:0006464 438 0.049
nucleoside phosphate catabolic process GO:1901292 110 0.049
organonitrogen compound catabolic process GO:1901565 128 0.047
Human
epithelial cell differentiation GO:0030855 322 0.047
purine nucleoside catabolic process GO:0006152 112 0.046
ribonucleoside metabolic process GO:0009119 127 0.046
organophosphate catabolic process GO:0046434 112 0.045
negative regulation of rna metabolic process GO:0051253 251 0.045
mitotic dna integrity checkpoint GO:0044774 75 0.044
endocytosis GO:0006897 310 0.044
ribonucleoside triphosphate metabolic process GO:0009199 119 0.044
dna metabolic process GO:0006259 227 0.043
organic cyclic compound catabolic process GO:1901361 168 0.042
cytoplasmic transport GO:0016482 130 0.041
phagocytosis GO:0006909 215 0.041
negative regulation of cell cycle phase transition GO:1901988 103 0.041
ribonucleoside triphosphate catabolic process GO:0009203 108 0.041
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.041
appendage development GO:0048736 401 0.040
nuclear division GO:0000280 332 0.040
purine nucleotide metabolic process GO:0006163 146 0.039
purine containing compound catabolic process GO:0072523 112 0.039
ovarian follicle cell development GO:0030707 248 0.038
purine ribonucleotide catabolic process GO:0009154 109 0.037
appendage morphogenesis GO:0035107 397 0.037
regionalization GO:0003002 416 0.037
chemotaxis GO:0006935 249 0.037
actin filament based process GO:0030029 220 0.037
cellular homeostasis GO:0019725 80 0.037
dna damage checkpoint GO:0000077 78 0.037
tube morphogenesis GO:0035239 191 0.036
negative regulation of rna biosynthetic process GO:1902679 240 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.036
purine nucleoside triphosphate metabolic process GO:0009144 119 0.036
central nervous system development GO:0007417 201 0.035
neurological system process GO:0050877 358 0.035
nucleoside catabolic process GO:0009164 112 0.035
dna repair GO:0006281 54 0.034
autophagy GO:0006914 108 0.034
male gamete generation GO:0048232 201 0.034
regulation of protein metabolic process GO:0051246 256 0.033
carbohydrate derivative catabolic process GO:1901136 118 0.033
defense response GO:0006952 300 0.033
regulation of transport GO:0051049 181 0.032
protein complex biogenesis GO:0070271 201 0.032
ribonucleoside monophosphate catabolic process GO:0009158 39 0.032
telencephalon development GO:0021537 2 0.032
ribose phosphate metabolic process GO:0019693 145 0.032
cellular response to chemical stimulus GO:0070887 199 0.032
double strand break repair GO:0006302 26 0.031
organic substance transport GO:0071702 257 0.031
regulation of nervous system development GO:0051960 248 0.031
response to oxygen containing compound GO:1901700 200 0.031
eye morphogenesis GO:0048592 260 0.031
nucleoside triphosphate catabolic process GO:0009143 108 0.031
imaginal disc derived wing morphogenesis GO:0007476 337 0.031
compound eye morphogenesis GO:0001745 249 0.031
ion transport GO:0006811 145 0.030
mrna transport GO:0051028 15 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.030
ribonucleotide catabolic process GO:0009261 109 0.030
nucleoside phosphate metabolic process GO:0006753 162 0.030
cell proliferation GO:0008283 299 0.030
positive regulation of multicellular organismal process GO:0051240 143 0.029
response to biotic stimulus GO:0009607 294 0.029
cellular amide metabolic process GO:0043603 80 0.029
Human
cell motility GO:0048870 251 0.029
response to inorganic substance GO:0010035 44 0.029
cellular response to endogenous stimulus GO:0071495 80 0.028
cell cycle checkpoint GO:0000075 95 0.028
single organism biosynthetic process GO:0044711 206 0.028
cellular modified amino acid metabolic process GO:0006575 45 0.028
tube development GO:0035295 244 0.028
anatomical structure homeostasis GO:0060249 97 0.028
regulation of intracellular signal transduction GO:1902531 236 0.028
small gtpase mediated signal transduction GO:0007264 88 0.027
regulation of cellular localization GO:0060341 136 0.027
cellular metal ion homeostasis GO:0006875 31 0.027
protein complex assembly GO:0006461 200 0.027
regulation of synapse structure and activity GO:0050803 128 0.027
regulation of developmental growth GO:0048638 174 0.027
developmental growth GO:0048589 280 0.027
negative regulation of nucleic acid templated transcription GO:1903507 240 0.027
single organism intracellular transport GO:1902582 207 0.026
regulation of intracellular transport GO:0032386 64 0.026
response to nutrient levels GO:0031667 114 0.026
translation GO:0006412 69 0.026
regulation of organelle organization GO:0033043 196 0.026
protein targeting to nucleus GO:0044744 51 0.025
dna integrity checkpoint GO:0031570 81 0.025
cellular amino acid metabolic process GO:0006520 61 0.025
establishment of localization in cell GO:0051649 402 0.025
negative regulation of mitotic cell cycle GO:0045930 109 0.025
nuclear transport GO:0051169 72 0.025
regulation of cellular catabolic process GO:0031329 157 0.025
response to organonitrogen compound GO:0010243 75 0.025
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.025
positive regulation of signal transduction GO:0009967 223 0.025
glutathione metabolic process GO:0006749 37 0.024
regulation of cell death GO:0010941 173 0.024
regulation of cellular component biogenesis GO:0044087 201 0.024
immune system process GO:0002376 347 0.024
regulation of small gtpase mediated signal transduction GO:0051056 93 0.024
cellular macromolecular complex assembly GO:0034622 153 0.024
intracellular transport GO:0046907 228 0.024
eggshell formation GO:0030703 105 0.024
body morphogenesis GO:0010171 2 0.023
morphogenesis of an epithelium GO:0002009 276 0.023
negative regulation of transcription dna templated GO:0045892 237 0.023
ribonucleoside monophosphate metabolic process GO:0009161 51 0.023
negative regulation of cellular component organization GO:0051129 108 0.023
establishment of organelle localization GO:0051656 122 0.023
response to endogenous stimulus GO:0009719 119 0.023
cell death GO:0008219 279 0.023
taxis GO:0042330 304 0.023
regulation of synapse assembly GO:0051963 94 0.023
actin filament organization GO:0007015 126 0.023
forebrain development GO:0030900 2 0.023
regulation of localization GO:0032879 275 0.023
embryo development ending in birth or egg hatching GO:0009792 152 0.022
regulation of growth GO:0040008 233 0.022
meiotic cell cycle GO:0051321 171 0.022
carbohydrate metabolic process GO:0005975 82 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.022
eye development GO:0001654 323 0.022
transition metal ion homeostasis GO:0055076 17 0.021
protein catabolic process GO:0030163 101 0.021
skin development GO:0043588 65 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
response to other organism GO:0051707 293 0.021
rna localization GO:0006403 115 0.021
cellular carbohydrate metabolic process GO:0044262 22 0.021
organelle localization GO:0051640 148 0.021
chromatin modification GO:0016568 147 0.021
guanosine containing compound metabolic process GO:1901068 74 0.020
regulation of meiosis GO:0040020 3 0.020
cell migration GO:0016477 238 0.020
peptide metabolic process GO:0006518 80 0.020
Human
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
response to external biotic stimulus GO:0043207 293 0.019
regulation of nuclear division GO:0051783 58 0.019
positive regulation of signaling GO:0023056 243 0.019
photoreceptor cell differentiation GO:0046530 170 0.019
response to bacterium GO:0009617 198 0.019
digestive tract morphogenesis GO:0048546 127 0.019
multicellular organismal reproductive behavior GO:0033057 110 0.019
positive regulation of cell communication GO:0010647 250 0.019
cellular ketone metabolic process GO:0042180 24 0.019
positive regulation of developmental process GO:0051094 143 0.019
protein dna complex subunit organization GO:0071824 86 0.019
digestive system development GO:0055123 149 0.019
macromolecule catabolic process GO:0009057 161 0.019
actin cytoskeleton organization GO:0030036 206 0.019
response to extracellular stimulus GO:0009991 116 0.019
regulation of translation GO:0006417 56 0.019
neuron projection guidance GO:0097485 241 0.019
defense response to other organism GO:0098542 225 0.019
imaginal disc derived appendage development GO:0048737 399 0.018
positive regulation of protein metabolic process GO:0051247 128 0.018
regulation of cell differentiation GO:0045595 302 0.018
camera type eye development GO:0043010 4 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
single organism carbohydrate metabolic process GO:0044723 72 0.018
apoptotic process GO:0006915 159 0.018
carbohydrate derivative biosynthetic process GO:1901137 85 0.018
guanosine containing compound catabolic process GO:1901069 74 0.018
response to abiotic stimulus GO:0009628 341 0.018
negative regulation of developmental process GO:0051093 201 0.018
eye photoreceptor cell differentiation GO:0001754 145 0.018
response to starvation GO:0042594 97 0.017
death GO:0016265 284 0.017
lipid biosynthetic process GO:0008610 46 0.017
positive regulation of catabolic process GO:0009896 105 0.017
positive regulation of transport GO:0051050 92 0.017
regulation of immune response GO:0050776 118 0.017
regulation of synapse organization GO:0050807 110 0.017
photoreceptor cell development GO:0042461 96 0.017
organelle fission GO:0048285 340 0.017
regulation of multicellular organismal development GO:2000026 414 0.017
locomotory behavior GO:0007626 176 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
regulation of cell division GO:0051302 72 0.016
protein localization to nucleus GO:0034504 55 0.016
synapse organization GO:0050808 196 0.016
regulation of catalytic activity GO:0050790 185 0.016
response to oxygen levels GO:0070482 59 0.016
notch signaling pathway GO:0007219 120 0.016
regulation of catabolic process GO:0009894 170 0.016
purine nucleoside monophosphate metabolic process GO:0009126 50 0.016
protein import into nucleus GO:0006606 51 0.016
positive regulation of phosphate metabolic process GO:0045937 139 0.016
regulation of multi organism process GO:0043900 131 0.015
histone modification GO:0016570 106 0.015
sex differentiation GO:0007548 81 0.015
single organism cellular localization GO:1902580 180 0.015
immune response GO:0006955 246 0.015
dna packaging GO:0006323 91 0.015
defense response to bacterium GO:0042742 178 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
regulation of ras protein signal transduction GO:0046578 93 0.015
organophosphate biosynthetic process GO:0090407 46 0.015
cell growth GO:0016049 108 0.015
response to hypoxia GO:0001666 53 0.015
retina development in camera type eye GO:0060041 4 0.015
muscle organ development GO:0007517 127 0.015
wing disc morphogenesis GO:0007472 344 0.015
regulation of innate immune response GO:0045088 71 0.015
regulation of programmed cell death GO:0043067 152 0.015
metal ion homeostasis GO:0055065 44 0.015
nucleocytoplasmic transport GO:0006913 72 0.015
compound eye photoreceptor cell differentiation GO:0001751 140 0.015
cellular response to starvation GO:0009267 61 0.015
gastrulation GO:0007369 70 0.015
multi organism behavior GO:0051705 175 0.015
cellular protein localization GO:0034613 160 0.015
regulation of cell development GO:0060284 215 0.015
mitochondrion organization GO:0007005 65 0.014
signal transduction by phosphorylation GO:0023014 107 0.014
protein complex disassembly GO:0043241 36 0.014
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
pigmentation GO:0043473 75 0.014
single organism nuclear import GO:1902593 51 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
regulation of protein catabolic process GO:0042176 55 0.014
regulation of apoptotic process GO:0042981 130 0.014
epidermis development GO:0008544 65 0.014
cell fate specification GO:0001708 71 0.014
mitotic nuclear division GO:0007067 213 0.014
histone ubiquitination GO:0016574 4 0.014
cellular amine metabolic process GO:0044106 12 0.014
head development GO:0060322 135 0.014
regulation of proteolysis GO:0030162 87 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
negative regulation of organelle organization GO:0010639 56 0.013
regulation of cytoplasmic transport GO:1903649 47 0.013
regulation of response to stress GO:0080134 200 0.013
regulation of anatomical structure size GO:0090066 163 0.013
cellular macromolecule localization GO:0070727 220 0.013
lateral inhibition GO:0046331 206 0.013
negative regulation of homeostatic process GO:0032845 2 0.013
regulation of response to external stimulus GO:0032101 115 0.013
single organism behavior GO:0044708 391 0.013
atp metabolic process GO:0046034 49 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
steroid catabolic process GO:0006706 1 0.013
establishment of protein localization GO:0045184 163 0.013
segmentation GO:0035282 207 0.013
embryonic pattern specification GO:0009880 174 0.013
regulation of mrna metabolic process GO:1903311 72 0.013
positive regulation of cell death GO:0010942 69 0.013
protein dna complex assembly GO:0065004 63 0.013
chemical homeostasis GO:0048878 92 0.013
spermatid development GO:0007286 98 0.013
developmental maturation GO:0021700 172 0.013
nucleoside monophosphate metabolic process GO:0009123 52 0.013
chromatin organization GO:0006325 207 0.012
organelle assembly GO:0070925 198 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
cellular response to organic substance GO:0071310 132 0.012
defense response to gram negative bacterium GO:0050829 94 0.012
regulation of autophagy GO:0010506 62 0.012
cellular response to hormone stimulus GO:0032870 44 0.012
cation homeostasis GO:0055080 51 0.012
phosphorylation GO:0016310 294 0.012
innate immune response GO:0045087 144 0.012
response to copper ion GO:0046688 4 0.012
regulation of protein localization GO:0032880 76 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
axonogenesis GO:0007409 290 0.012
peripheral nervous system development GO:0007422 52 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
response to glucose GO:0009749 2 0.011
atp catabolic process GO:0006200 38 0.011
ion homeostasis GO:0050801 55 0.011
meiotic nuclear division GO:0007126 151 0.011
axon development GO:0061564 297 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
secretion by cell GO:0032940 101 0.011
cellular response to hexose stimulus GO:0071331 1 0.011
negative regulation of growth GO:0045926 84 0.011
gastrulation with mouth forming first GO:0001703 36 0.011
positive regulation of cell motility GO:2000147 3 0.011
response to organic substance GO:0010033 284 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
positive regulation of cell cycle GO:0045787 43 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
ventral furrow formation GO:0007370 17 0.011
tissue death GO:0016271 102 0.011
establishment of rna localization GO:0051236 47 0.011
muscle structure development GO:0061061 224 0.011
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
establishment of protein localization to organelle GO:0072594 62 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
eye photoreceptor cell development GO:0042462 81 0.011
pronuclear migration GO:0035046 4 0.011
regulation of intracellular protein transport GO:0033157 46 0.010
nucleotide metabolic process GO:0009117 161 0.010
response to lipopolysaccharide GO:0032496 4 0.010
ras protein signal transduction GO:0007265 88 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
programmed cell death GO:0012501 257 0.010
response to transition metal nanoparticle GO:1990267 9 0.010
cellular response to carbohydrate stimulus GO:0071322 4 0.010
regulation of phosphate metabolic process GO:0019220 210 0.010
nucleoside monophosphate catabolic process GO:0009125 39 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
negative regulation of nervous system development GO:0051961 92 0.010
dendrite morphogenesis GO:0048813 199 0.010
chaeta development GO:0022416 97 0.010
amine metabolic process GO:0009308 12 0.010
axon guidance GO:0007411 233 0.010
brain development GO:0007420 120 0.010
chromosome organization GO:0051276 360 0.010

ApepP disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.072
nervous system disease DOID:863 0 0.015