Drosophila melanogaster

0 known processes

Cyp12a5 (Dmel_CG11821)

CG11821 gene product from transcript CG11821-RA

(Aliases: CG11821,Dmel\CG11821,12a5)

Cyp12a5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
insecticide metabolic process GO:0017143 2 0.978
secondary metabolite catabolic process GO:0090487 1 0.938
medium chain fatty acid metabolic process GO:0051791 1 0.929
toxin catabolic process GO:0009407 1 0.772
lauric acid metabolic process GO:0048252 1 0.742
polyol biosynthetic process GO:0046173 3 0.700
insecticide catabolic process GO:0046701 1 0.682
response to mercury ion GO:0046689 3 0.672
toxin metabolic process GO:0009404 2 0.476
anion homeostasis GO:0055081 3 0.369
steroid catabolic process GO:0006706 1 0.331
vitamin biosynthetic process GO:0009110 1 0.311
steroid biosynthetic process GO:0006694 16 0.284
Fly
sensory perception of chemical stimulus GO:0007606 116 0.267
fat soluble vitamin metabolic process GO:0006775 1 0.253
ketone biosynthetic process GO:0042181 16 0.235
Fly
fat soluble vitamin biosynthetic process GO:0042362 1 0.214
cellular ketone metabolic process GO:0042180 24 0.206
Fly
response to organophosphorus GO:0046683 2 0.201
sensory perception of smell GO:0007608 80 0.199
xenobiotic catabolic process GO:0042178 1 0.194
lipid metabolic process GO:0006629 121 0.182
Fly
neurological system process GO:0050877 358 0.182
ecdysteroid biosynthetic process GO:0045456 15 0.175
Fly
response to ddt GO:0046680 5 0.161
Fly
response to caffeine GO:0031000 12 0.157
response to biotic stimulus GO:0009607 294 0.145
vitamin metabolic process GO:0006766 2 0.142
ecdysteroid metabolic process GO:0045455 19 0.138
Fly
multi organism behavior GO:0051705 175 0.129
aggressive behavior GO:0002118 63 0.128
response to toxic substance GO:0009636 22 0.122
Fly
single organism behavior GO:0044708 391 0.116
response to other organism GO:0051707 293 0.113
ecdysone biosynthetic process GO:0006697 9 0.108
Fly
positive regulation of gene expression GO:0010628 290 0.106
regulation of developmental growth GO:0048638 174 0.103
response to insecticide GO:0017085 14 0.099
Fly
organic hydroxy compound metabolic process GO:1901615 83 0.098
Fly
secondary metabolic process GO:0019748 75 0.098
response to temperature stimulus GO:0009266 106 0.096
lipid biosynthetic process GO:0008610 46 0.095
Fly
chemical homeostasis GO:0048878 92 0.095
growth GO:0040007 359 0.095
Fly
alcohol biosynthetic process GO:0046165 14 0.093
Fly
hormone biosynthetic process GO:0042446 20 0.092
Fly
single organism biosynthetic process GO:0044711 206 0.092
Fly
response to abiotic stimulus GO:0009628 341 0.092
cellular catabolic process GO:0044248 372 0.090
developmental growth GO:0048589 280 0.090
Fly
response to organic substance GO:0010033 284 0.089
Fly
defense response to other organism GO:0098542 225 0.086
homeostatic process GO:0042592 199 0.084
organonitrogen compound metabolic process GO:1901564 318 0.083
aging GO:0007568 143 0.083
regulation of blood circulation GO:1903522 21 0.080
sensory perception GO:0007600 196 0.079
cellular lipid metabolic process GO:0044255 83 0.076
response to extracellular stimulus GO:0009991 116 0.075
defense response to bacterium GO:0042742 178 0.075
organic hydroxy compound biosynthetic process GO:1901617 21 0.075
Fly
response to external biotic stimulus GO:0043207 293 0.070
ecdysone metabolic process GO:0008205 11 0.070
Fly
neutral lipid biosynthetic process GO:0046460 2 0.069
defense response to gram negative bacterium GO:0050829 94 0.065
small molecule metabolic process GO:0044281 305 0.064
Fly
regulation of anatomical structure size GO:0090066 163 0.063
sterol biosynthetic process GO:0016126 9 0.062
Fly
sterol metabolic process GO:0016125 12 0.061
Fly
regulation of hormone levels GO:0010817 40 0.061
Fly
small molecule biosynthetic process GO:0044283 37 0.061
Fly
regulation of growth GO:0040008 233 0.058
response to nutrient levels GO:0031667 114 0.056
positive regulation of macromolecule metabolic process GO:0010604 405 0.056
carboxylic acid metabolic process GO:0019752 92 0.055
regulation of tube size GO:0035150 46 0.053
defense response GO:0006952 300 0.053
cellular nitrogen compound catabolic process GO:0044270 165 0.053
hormone metabolic process GO:0042445 33 0.052
Fly
ion homeostasis GO:0050801 55 0.048
regulation of system process GO:0044057 36 0.048
alcohol metabolic process GO:0006066 25 0.046
Fly
epithelial cell differentiation GO:0030855 322 0.046
Fly
wing disc morphogenesis GO:0007472 344 0.046
ovarian follicle cell development GO:0030707 248 0.045
Fly
response to purine containing compound GO:0014074 12 0.044
imaginal disc derived wing morphogenesis GO:0007476 337 0.043
terpenoid metabolic process GO:0006721 7 0.043
response to alkaloid GO:0043279 26 0.042
response to organonitrogen compound GO:0010243 75 0.041
epithelial cell development GO:0002064 274 0.041
Fly
epithelium migration GO:0090132 148 0.041
Fly
cellular protein modification process GO:0006464 438 0.041
protein modification process GO:0036211 438 0.041
epithelial cell migration GO:0010631 148 0.040
Fly
fatty acid metabolic process GO:0006631 20 0.040
organonitrogen compound catabolic process GO:1901565 128 0.040
imaginal disc derived appendage development GO:0048737 399 0.039
chaeta development GO:0022416 97 0.039
response to nitrogen compound GO:1901698 90 0.039
oxoacid metabolic process GO:0043436 103 0.039
cellular response to chemical stimulus GO:0070887 199 0.038
response to transition metal nanoparticle GO:1990267 9 0.037
positive regulation of multicellular organismal process GO:0051240 143 0.037
cellular chemical homeostasis GO:0055082 40 0.036
estrogen metabolic process GO:0008210 1 0.035
ameboidal type cell migration GO:0001667 151 0.034
Fly
appendage development GO:0048736 401 0.034
response to organic cyclic compound GO:0014070 89 0.034
Fly
response to radiation GO:0009314 155 0.034
single organism catabolic process GO:0044712 228 0.033
organic substance catabolic process GO:1901575 308 0.033
acylglycerol biosynthetic process GO:0046463 2 0.032
oxidation reduction process GO:0055114 123 0.032
Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.032
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.032
post embryonic appendage morphogenesis GO:0035120 385 0.032
response to copper ion GO:0046688 4 0.031
response to lipopolysaccharide GO:0032496 4 0.031
appendage morphogenesis GO:0035107 397 0.031
catabolic process GO:0009056 409 0.031
response to light stimulus GO:0009416 124 0.031
regulation of localization GO:0032879 275 0.031
regulation of multicellular organismal development GO:2000026 414 0.031
response to hormone GO:0009725 45 0.031
taxis GO:0042330 304 0.030
embryonic development via the syncytial blastoderm GO:0001700 148 0.030
Fly
organic cyclic compound catabolic process GO:1901361 168 0.029
blood circulation GO:0008015 26 0.029
cellular homeostasis GO:0019725 80 0.029
multicellular organismal aging GO:0010259 140 0.028
lipid catabolic process GO:0016042 21 0.028
regulation of response to stress GO:0080134 200 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.027
ethanolamine containing compound metabolic process GO:0042439 4 0.027
regulation of cellular ketone metabolic process GO:0010565 3 0.027
response to xenobiotic stimulus GO:0009410 5 0.027
activation of innate immune response GO:0002218 4 0.026
phosphorylation GO:0016310 294 0.026
cellular response to xenobiotic stimulus GO:0071466 5 0.026
cell migration GO:0016477 238 0.026
Fly
immune response regulating signaling pathway GO:0002764 2 0.025
positive regulation of response to stimulus GO:0048584 323 0.025
cell motility GO:0048870 251 0.025
Fly
response to endogenous stimulus GO:0009719 119 0.025
pattern recognition receptor signaling pathway GO:0002221 2 0.025
tissue migration GO:0090130 155 0.025
Fly
response to bacterium GO:0009617 198 0.025
cell proliferation GO:0008283 299 0.025
negative regulation of cellular biosynthetic process GO:0031327 277 0.024
positive regulation of cell migration GO:0030335 2 0.024
innate immune response activating signal transduction GO:0002758 2 0.023
camera type eye development GO:0043010 4 0.023
organic acid metabolic process GO:0006082 103 0.023
immune system process GO:0002376 347 0.023
response to lipid GO:0033993 38 0.023
regulation of multi organism process GO:0043900 131 0.023
triglyceride biosynthetic process GO:0019432 2 0.023
intracellular signal transduction GO:0035556 300 0.023
axonogenesis GO:0007409 290 0.023
steroid metabolic process GO:0008202 20 0.023
Fly
regionalization GO:0003002 416 0.023
amine metabolic process GO:0009308 12 0.023
immune response activating signal transduction GO:0002757 2 0.022
embryo development ending in birth or egg hatching GO:0009792 152 0.022
Fly
regulation of transport GO:0051049 181 0.022
body morphogenesis GO:0010171 2 0.022
ovarian follicle cell migration GO:0007297 121 0.022
Fly
circulatory system process GO:0003013 37 0.022
negative regulation of signaling GO:0023057 219 0.022
positive regulation of cell motility GO:2000147 3 0.022
cellular hormone metabolic process GO:0034754 23 0.021
Fly
border follicle cell migration GO:0007298 113 0.021
Fly
tissue morphogenesis GO:0048729 297 0.021
Fly
negative regulation of cell communication GO:0010648 223 0.021
kidney development GO:0001822 3 0.021
regulation of cell differentiation GO:0045595 302 0.021
isoprenoid metabolic process GO:0006720 8 0.021
regulation of protein metabolic process GO:0051246 256 0.020
response to metal ion GO:0010038 23 0.020
vesicle mediated transport GO:0016192 381 0.020
biological adhesion GO:0022610 138 0.020
response to oxygen containing compound GO:1901700 200 0.020
digestive system development GO:0055123 149 0.020
Fly
cellular amino acid metabolic process GO:0006520 61 0.020
neuron projection guidance GO:0097485 241 0.020
negative regulation of response to stimulus GO:0048585 258 0.020
endocytosis GO:0006897 310 0.020
regulation of molecular function GO:0065009 217 0.020
localization of cell GO:0051674 257 0.019
Fly
compound eye development GO:0048749 307 0.019
determination of adult lifespan GO:0008340 137 0.019
telencephalon development GO:0021537 2 0.019
regulation of cell cycle GO:0051726 291 0.019
forebrain development GO:0030900 2 0.018
circadian rhythm GO:0007623 105 0.018
morphogenesis of an epithelium GO:0002009 276 0.018
Fly
central nervous system development GO:0007417 201 0.018
Fly
androgen metabolic process GO:0008209 1 0.018
negative regulation of biosynthetic process GO:0009890 277 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
rhythmic process GO:0048511 106 0.018
tube development GO:0035295 244 0.018
Fly
positive regulation of cell communication GO:0010647 250 0.017
positive regulation of signal transduction GO:0009967 223 0.017
detection of stimulus GO:0051606 156 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
regulation of immune system process GO:0002682 176 0.017
establishment of localization in cell GO:0051649 402 0.017
death GO:0016265 284 0.017
mating GO:0007618 120 0.017
response to cadmium ion GO:0046686 9 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
macromolecular complex assembly GO:0065003 256 0.017
transmembrane transport GO:0055085 139 0.017
dorsal closure GO:0007391 79 0.017
Fly
chemotaxis GO:0006935 249 0.017
macromolecule catabolic process GO:0009057 161 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.016
organelle fission GO:0048285 340 0.016
response to inorganic substance GO:0010035 44 0.016
negative regulation of signal transduction GO:0009968 206 0.016
negative regulation of gene expression GO:0010629 387 0.016
cell death GO:0008219 279 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
morphogenesis of embryonic epithelium GO:0016331 94 0.016
Fly
cuticle development GO:0042335 86 0.016
Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.016
cation transport GO:0006812 110 0.016
connective tissue development GO:0061448 3 0.016
lateral inhibition GO:0046331 206 0.016
compound eye morphogenesis GO:0001745 249 0.015
axon development GO:0061564 297 0.015
regulation of behavior GO:0050795 75 0.015
cellular amine metabolic process GO:0044106 12 0.015
protein phosphorylation GO:0006468 169 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
immune effector process GO:0002252 98 0.015
organic substance transport GO:0071702 257 0.015
response to glucose GO:0009749 2 0.015
neurotransmitter metabolic process GO:0042133 2 0.015
l amino acid import GO:0043092 2 0.015
gland development GO:0048732 191 0.015
head involution GO:0008258 35 0.015
Fly
phagocytosis GO:0006909 215 0.015
xenobiotic metabolic process GO:0006805 5 0.015
digestive tract development GO:0048565 149 0.015
Fly
positive regulation of signaling GO:0023056 243 0.014
response to monosaccharide GO:0034284 4 0.014
midgut development GO:0007494 23 0.014
Fly
developmental maturation GO:0021700 172 0.014
sensory organ morphogenesis GO:0090596 260 0.014
nuclear division GO:0000280 332 0.014
protein localization GO:0008104 284 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
protein complex assembly GO:0006461 200 0.014
ras protein signal transduction GO:0007265 88 0.014
respiratory system development GO:0060541 213 0.014
acetate ester metabolic process GO:1900619 2 0.014
immune response GO:0006955 246 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
aromatic compound catabolic process GO:0019439 166 0.014
small gtpase mediated signal transduction GO:0007264 88 0.013
acylglycerol catabolic process GO:0046464 3 0.013
innate immune response GO:0045087 144 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
inter male aggressive behavior GO:0002121 60 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
response to hexose GO:0009746 3 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
detection of abiotic stimulus GO:0009582 66 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
eye development GO:0001654 323 0.013
regulation of immune response GO:0050776 118 0.013
positive regulation of lipid storage GO:0010884 4 0.013
synaptic transmission GO:0007268 288 0.013
regulation of response to external stimulus GO:0032101 115 0.013
eye morphogenesis GO:0048592 260 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
imaginal disc pattern formation GO:0007447 91 0.013
regulation of catalytic activity GO:0050790 185 0.013
gland morphogenesis GO:0022612 145 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
Fly
protein complex biogenesis GO:0070271 201 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
triglyceride catabolic process GO:0019433 3 0.013
thermosensory behavior GO:0040040 19 0.013
programmed cell death GO:0012501 257 0.013
water homeostasis GO:0030104 3 0.012
open tracheal system development GO:0007424 204 0.012
positive regulation of molecular function GO:0044093 136 0.012
heterocycle catabolic process GO:0046700 166 0.012
adult behavior GO:0030534 137 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
tergite morphogenesis GO:0007490 1 0.012
Fly
regulation of cellular localization GO:0060341 136 0.012
hormone catabolic process GO:0042447 3 0.012
leg disc development GO:0035218 92 0.012
organophosphate metabolic process GO:0019637 195 0.012
response to drug GO:0042493 17 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
cell adhesion GO:0007155 136 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
single organism intracellular transport GO:1902582 207 0.012
positive regulation of biosynthetic process GO:0009891 316 0.012
actin filament based process GO:0030029 220 0.012
regulation of cell death GO:0010941 173 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
phosphatidylethanolamine metabolic process GO:0046337 1 0.012
regulation of reproductive process GO:2000241 54 0.012
cellular biogenic amine catabolic process GO:0042402 1 0.012
spindle organization GO:0007051 253 0.012
exocrine system development GO:0035272 162 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
salivary gland morphogenesis GO:0007435 145 0.012
mrna metabolic process GO:0016071 124 0.012
regulation of defense response GO:0031347 102 0.012
ion transport GO:0006811 145 0.012
response to starvation GO:0042594 97 0.012
positive regulation of immune response GO:0050778 63 0.012
cellular response to hexose stimulus GO:0071331 1 0.012
cellular macromolecule localization GO:0070727 220 0.012
cholesterol homeostasis GO:0042632 3 0.012
salivary gland histolysis GO:0035070 88 0.012
l glutamate import GO:0051938 1 0.012
axon guidance GO:0007411 233 0.012
apoptotic process GO:0006915 159 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
multi organism reproductive behavior GO:0044705 121 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.011
camera type eye morphogenesis GO:0048593 2 0.011
rna processing GO:0006396 147 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
embryonic morphogenesis GO:0048598 206 0.011
Fly
choline metabolic process GO:0019695 1 0.011
neuron recognition GO:0008038 101 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
chemosensory behavior GO:0007635 106 0.011
positive regulation of sequestering of triglyceride GO:0010890 1 0.011
mitotic nuclear division GO:0007067 213 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
cholesterol transport GO:0030301 2 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
negative regulation of developmental process GO:0051093 201 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
mrna processing GO:0006397 104 0.011
cellular amide metabolic process GO:0043603 80 0.011
ion transmembrane transport GO:0034220 122 0.011
autophagy GO:0006914 108 0.011
carbohydrate metabolic process GO:0005975 82 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
sterol homeostasis GO:0055092 4 0.011
glycerolipid catabolic process GO:0046503 3 0.011
regulation of response to biotic stimulus GO:0002831 63 0.011
autophagic cell death GO:0048102 83 0.011
chitin based cuticle development GO:0040003 49 0.011
Fly
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.011
Fly
cellular macromolecule catabolic process GO:0044265 136 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
tissue death GO:0016271 102 0.011
phosphatidic acid metabolic process GO:0046473 1 0.011
rhythmic behavior GO:0007622 76 0.011
inorganic ion transmembrane transport GO:0098660 73 0.011
hindbrain development GO:0030902 2 0.011
proteolysis GO:0006508 192 0.011
single organism cellular localization GO:1902580 180 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
regulation of innate immune response GO:0045088 71 0.010
cell maturation GO:0048469 144 0.010
segmentation GO:0035282 207 0.010
establishment of protein localization GO:0045184 163 0.010
synapse assembly GO:0007416 143 0.010
monocarboxylic acid metabolic process GO:0032787 29 0.010
cell recognition GO:0008037 102 0.010
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.010
male gamete generation GO:0048232 201 0.010
regulation of phosphorylation GO:0042325 147 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
maintenance of location GO:0051235 73 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
positive regulation of nucleic acid templated transcription GO:1903508 266 0.010
mapk cascade GO:0000165 107 0.010
imaginal disc derived wing vein specification GO:0007474 48 0.010

Cyp12a5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
hypertension DOID:10763 0 0.638
artery disease DOID:0050828 0 0.638
disease of anatomical entity DOID:7 0 0.638
vascular disease DOID:178 0 0.638
essential hypertension DOID:10825 0 0.638
cardiovascular system disease DOID:1287 0 0.638
renal tubular transport disease DOID:447 0 0.052
kidney disease DOID:557 0 0.052
urinary system disease DOID:18 0 0.052
disease of metabolism DOID:0014667 0 0.022
inherited metabolic disorder DOID:655 0 0.022
nervous system disease DOID:863 0 0.019
acquired metabolic disease DOID:0060158 0 0.013
carbohydrate metabolism disease DOID:0050013 0 0.012
glucose metabolism disease DOID:4194 0 0.012
hair disease DOID:421 0 0.011
integumentary system disease DOID:16 0 0.011
hypotrichosis DOID:4535 0 0.011
sensory system disease DOID:0050155 0 0.011
diabetes mellitus DOID:9351 0 0.011
musculoskeletal system disease DOID:17 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010
type 2 diabetes mellitus DOID:9352 0 0.010