Drosophila melanogaster

109 known processes

swm (Dmel_CG10084)

second mitotic wave missing

(Aliases: l(2)E1,Swm,Dmel\CG10084,CG10084,l(2)37Dh,S(Rux)2B,E1,S(rux)2B)

swm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.610
proteolysis GO:0006508 192 0.535
cellular protein modification process GO:0006464 438 0.481
negative regulation of cell cycle phase transition GO:1901988 103 0.454
negative regulation of gene expression GO:0010629 387 0.413
regulation of proteolysis GO:0030162 87 0.358
chromosome organization GO:0051276 360 0.318
regulation of cell cycle GO:0051726 291 0.313
growth GO:0040007 359 0.299
cell death GO:0008219 279 0.290
regulation of cell cycle process GO:0010564 181 0.254
ubiquitin dependent protein catabolic process GO:0006511 78 0.250
regulation of peptidase activity GO:0052547 39 0.235
regulation of mitotic cell cycle GO:0007346 190 0.232
cellular macromolecule catabolic process GO:0044265 136 0.230
proteasomal protein catabolic process GO:0010498 59 0.226
organelle fission GO:0048285 340 0.220
stem cell maintenance GO:0019827 67 0.220
regulation of protein metabolic process GO:0051246 256 0.217
mitotic dna integrity checkpoint GO:0044774 75 0.206
stem cell differentiation GO:0048863 117 0.194
negative regulation of translation GO:0017148 28 0.189
regulation of mrna 3 end processing GO:0031440 7 0.185
mitotic g2 dna damage checkpoint GO:0007095 69 0.185
protein modification process GO:0036211 438 0.178
mitotic cell cycle phase transition GO:0044772 138 0.175
anterior posterior pattern specification GO:0009952 136 0.168
regulation of cell cycle phase transition GO:1901987 130 0.166
stem cell development GO:0048864 79 0.163
response to light stimulus GO:0009416 124 0.160
regionalization GO:0003002 416 0.156
male gamete generation GO:0048232 201 0.151
tor signaling GO:0031929 32 0.145
cell cycle phase transition GO:0044770 140 0.144
mitotic dna damage checkpoint GO:0044773 74 0.134
post embryonic appendage morphogenesis GO:0035120 385 0.133
death GO:0016265 284 0.130
translation GO:0006412 69 0.128
positive regulation of proteolysis GO:0045862 52 0.127
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.126
dorsal ventral pattern formation GO:0009953 133 0.126
spermatogenesis GO:0007283 200 0.123
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.119
regulation of cellular protein metabolic process GO:0032268 243 0.119
negative regulation of mitotic cell cycle GO:0045930 109 0.118
negative regulation of cellular biosynthetic process GO:0031327 277 0.115
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.108
oocyte microtubule cytoskeleton organization GO:0016325 35 0.106
negative regulation of developmental process GO:0051093 201 0.105
positive regulation of macromolecule metabolic process GO:0010604 405 0.104
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.104
establishment of organelle localization GO:0051656 122 0.103
cellular protein catabolic process GO:0044257 83 0.100
negative regulation of cellular protein metabolic process GO:0032269 85 0.099
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.097
modification dependent macromolecule catabolic process GO:0043632 79 0.095
cell division GO:0051301 248 0.093
positive regulation of cell communication GO:0010647 250 0.089
positive regulation of peptidase activity GO:0010952 29 0.089
aging GO:0007568 143 0.088
imaginal disc derived appendage development GO:0048737 399 0.087
localization of cell GO:0051674 257 0.086
response to other organism GO:0051707 293 0.080
negative regulation of cell cycle process GO:0010948 109 0.080
response to organic substance GO:0010033 284 0.079
endocytosis GO:0006897 310 0.078
cellular catabolic process GO:0044248 372 0.077
regulation of mitosis GO:0007088 56 0.074
mitotic cell cycle checkpoint GO:0007093 88 0.073
negative regulation of cellular metabolic process GO:0031324 382 0.073
positive regulation of gene expression GO:0010628 290 0.072
response to external biotic stimulus GO:0043207 293 0.072
defense response to bacterium GO:0042742 178 0.072
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.071
protein complex disassembly GO:0043241 36 0.070
nuclear division GO:0000280 332 0.069
cell maturation GO:0048469 144 0.069
epithelial cell differentiation GO:0030855 322 0.067
ovarian nurse cell to oocyte transport GO:0007300 27 0.065
response to radiation GO:0009314 155 0.061
mitotic spindle elongation GO:0000022 81 0.060
transcription from rna polymerase ii promoter GO:0006366 368 0.059
head development GO:0060322 135 0.059
positive regulation of rna metabolic process GO:0051254 271 0.059
macromolecule catabolic process GO:0009057 161 0.058
pole plasm mrna localization GO:0019094 49 0.058
regulation of molecular function GO:0065009 217 0.056
regulation of translation GO:0006417 56 0.056
erbb signaling pathway GO:0038127 58 0.056
regulation of mitotic cell cycle phase transition GO:1901990 130 0.055
tripartite regional subdivision GO:0007351 103 0.055
regulation of epithelial cell differentiation GO:0030856 4 0.054
phosphorylation GO:0016310 294 0.053
positive regulation of nucleic acid templated transcription GO:1903508 266 0.052
phagocytosis GO:0006909 215 0.051
positive regulation of protein metabolic process GO:0051247 128 0.051
dna repair GO:0006281 54 0.049
single organism intracellular transport GO:1902582 207 0.049
response to bacterium GO:0009617 198 0.049
innate immune response GO:0045087 144 0.049
compound eye development GO:0048749 307 0.047
eggshell formation GO:0030703 105 0.047
protein processing GO:0016485 68 0.047
axis specification GO:0009798 167 0.047
epithelial cell development GO:0002064 274 0.046
mitotic nuclear division GO:0007067 213 0.045
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.045
negative regulation of multicellular organismal process GO:0051241 142 0.045
imaginal disc derived wing morphogenesis GO:0007476 337 0.045
organic substance transport GO:0071702 257 0.044
wing disc morphogenesis GO:0007472 344 0.044
cellular response to dna damage stimulus GO:0006974 223 0.044
photoreceptor cell differentiation GO:0046530 170 0.044
embryonic axis specification GO:0000578 107 0.044
cell migration GO:0016477 238 0.043
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.043
protein catabolic process GO:0030163 101 0.042
regulation of nuclear division GO:0051783 58 0.042
ovarian follicle cell development GO:0030707 248 0.041
positive regulation of phosphorylation GO:0042327 87 0.041
smoothened signaling pathway GO:0007224 49 0.041
response to biotic stimulus GO:0009607 294 0.041
regulation of cysteine type endopeptidase activity GO:2000116 27 0.040
blastoderm segmentation GO:0007350 159 0.040
response to extracellular stimulus GO:0009991 116 0.040
positive regulation of molecular function GO:0044093 136 0.039
response to oxygen containing compound GO:1901700 200 0.039
positive regulation of signal transduction GO:0009967 223 0.039
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.039
embryonic development via the syncytial blastoderm GO:0001700 148 0.039
positive regulation of biosynthetic process GO:0009891 316 0.039
columnar cuboidal epithelial cell development GO:0002066 249 0.038
regulation of hydrolase activity GO:0051336 97 0.038
enzyme linked receptor protein signaling pathway GO:0007167 179 0.037
neuroblast proliferation GO:0007405 74 0.037
negative regulation of protein metabolic process GO:0051248 85 0.037
rhythmic behavior GO:0007622 76 0.037
ovarian follicle cell migration GO:0007297 121 0.037
regulation of wnt signaling pathway GO:0030111 68 0.036
g2 dna damage checkpoint GO:0031572 69 0.036
positive regulation of transcription dna templated GO:0045893 266 0.036
regulation of catalytic activity GO:0050790 185 0.036
positive regulation of cellular protein metabolic process GO:0032270 118 0.035
modification dependent protein catabolic process GO:0019941 78 0.035
single organism behavior GO:0044708 391 0.034
digestive tract development GO:0048565 149 0.033
protein dephosphorylation GO:0006470 27 0.033
response to alcohol GO:0097305 95 0.033
cell motility GO:0048870 251 0.032
mitotic g2 m transition checkpoint GO:0044818 70 0.032
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.032
programmed cell death GO:0012501 257 0.031
appendage development GO:0048736 401 0.031
regulation of growth GO:0040008 233 0.031
macromolecular complex assembly GO:0065003 256 0.031
Worm
protein maturation GO:0051604 71 0.029
negative regulation of programmed cell death GO:0043069 72 0.029
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.029
positive regulation of rna biosynthetic process GO:1902680 266 0.029
cortical cytoskeleton organization GO:0030865 29 0.029
posttranscriptional regulation of gene expression GO:0010608 145 0.028
rna localization GO:0006403 115 0.028
negative regulation of apoptotic process GO:0043066 63 0.028
cytoplasmic translation GO:0002181 0 0.027
regulation of cellular component size GO:0032535 98 0.027
spindle elongation GO:0051231 83 0.027
positive regulation of cellular component biogenesis GO:0044089 80 0.027
cell proliferation GO:0008283 299 0.026
positive regulation of signaling GO:0023056 243 0.026
head involution GO:0008258 35 0.026
homeostatic process GO:0042592 199 0.026
developmental growth GO:0048589 280 0.026
protein modification by small protein conjugation or removal GO:0070647 106 0.026
chromatin organization GO:0006325 207 0.025
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.025
germline ring canal formation GO:0030725 13 0.024
negative regulation of growth GO:0045926 84 0.024
macromolecular complex disassembly GO:0032984 37 0.024
embryonic morphogenesis GO:0048598 206 0.024
regulation of apoptotic process GO:0042981 130 0.024
activation of cysteine type endopeptidase activity GO:0097202 17 0.024
spinal cord development GO:0021510 1 0.024
epithelium migration GO:0090132 148 0.023
negative regulation of cell cycle GO:0045786 116 0.023
protein targeting GO:0006605 64 0.023
meiosis i GO:0007127 59 0.023
chromosome segregation GO:0007059 157 0.023
mitotic cell cycle embryonic GO:0045448 38 0.023
imaginal disc derived appendage morphogenesis GO:0035114 395 0.023
sensory organ morphogenesis GO:0090596 260 0.023
immune response GO:0006955 246 0.023
organic substance catabolic process GO:1901575 308 0.023
negative regulation of biosynthetic process GO:0009890 277 0.023
chromatin modification GO:0016568 147 0.022
anterior posterior axis specification GO:0009948 109 0.022
establishment or maintenance of cell polarity GO:0007163 167 0.022
cell aging GO:0007569 2 0.022
regulation of multicellular organismal development GO:2000026 414 0.022
ribonucleoprotein complex subunit organization GO:0071826 28 0.021
regulation of organelle organization GO:0033043 196 0.021
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.021
regulation of cell death GO:0010941 173 0.021
positive regulation of mrna processing GO:0050685 4 0.021
apoptotic process GO:0006915 159 0.021
tissue migration GO:0090130 155 0.021
cellular response to organonitrogen compound GO:0071417 36 0.020
regulation of protein catabolic process GO:0042176 55 0.020
regulation of cell division GO:0051302 72 0.020
purine ribonucleotide catabolic process GO:0009154 109 0.020
muscle structure development GO:0061061 224 0.020
Worm
cellular macromolecule localization GO:0070727 220 0.020
dna damage checkpoint GO:0000077 78 0.020
regulation of phosphorylation GO:0042325 147 0.020
morphogenesis of follicular epithelium GO:0016333 36 0.020
developmental maturation GO:0021700 172 0.020
embryo development ending in birth or egg hatching GO:0009792 152 0.020
positive regulation of cell cycle GO:0045787 43 0.020
response to organonitrogen compound GO:0010243 75 0.019
positive regulation of cellular component organization GO:0051130 156 0.019
positive regulation of response to stimulus GO:0048584 323 0.019
ameboidal type cell migration GO:0001667 151 0.019
cellular response to chemical stimulus GO:0070887 199 0.019
cellular response to nitrogen compound GO:1901699 51 0.019
appendage morphogenesis GO:0035107 397 0.019
catabolic process GO:0009056 409 0.019
intracellular signal transduction GO:0035556 300 0.019
protein polymerization GO:0051258 42 0.019
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
Worm
cellular response to organic substance GO:0071310 132 0.018
neurological system process GO:0050877 358 0.018
protein phosphorylation GO:0006468 169 0.018
intracellular mrna localization GO:0008298 66 0.018
spermatid development GO:0007286 98 0.018
nuclear transport GO:0051169 72 0.018
positive regulation of intracellular signal transduction GO:1902533 116 0.018
protein localization to organelle GO:0033365 82 0.018
response to abiotic stimulus GO:0009628 341 0.018
female germline ring canal formation GO:0007301 9 0.017
oocyte development GO:0048599 124 0.017
regulation of organ morphogenesis GO:2000027 78 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
defense response to gram negative bacterium GO:0050829 94 0.017
spindle organization GO:0007051 253 0.017
positive regulation of cell migration GO:0030335 2 0.017
regulation of response to stress GO:0080134 200 0.017
pole plasm rna localization GO:0007316 52 0.017
gliogenesis GO:0042063 80 0.017
dorsal ventral axis specification GO:0009950 66 0.017
positive regulation of cell motility GO:2000147 3 0.016
cytoplasmic transport GO:0016482 130 0.016
regulation of developmental growth GO:0048638 174 0.016
mitotic sister chromatid segregation GO:0000070 87 0.016
dna biosynthetic process GO:0071897 24 0.016
cortical actin cytoskeleton organization GO:0030866 24 0.016
organic acid metabolic process GO:0006082 103 0.016
lipid storage GO:0019915 38 0.015
maintenance of location GO:0051235 73 0.015
segmentation GO:0035282 207 0.015
single organism cellular localization GO:1902580 180 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
regulation of mitotic sister chromatid segregation GO:0033047 28 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
central nervous system development GO:0007417 201 0.015
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.015
organelle assembly GO:0070925 198 0.015
Worm
regulation of localization GO:0032879 275 0.015
carbohydrate metabolic process GO:0005975 82 0.015
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.015
cell growth GO:0016049 108 0.015
response to lipopolysaccharide GO:0032496 4 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.015
camera type eye development GO:0043010 4 0.014
somatic muscle development GO:0007525 66 0.014
embryonic pattern specification GO:0009880 174 0.014
adult behavior GO:0030534 137 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
negative regulation of cell communication GO:0010648 223 0.014
ribonucleoprotein complex biogenesis GO:0022613 31 0.014
stress activated protein kinase signaling cascade GO:0031098 55 0.014
cellular protein complex disassembly GO:0043624 35 0.014
organelle localization GO:0051640 148 0.014
regulation of synapse organization GO:0050807 110 0.013
mapk cascade GO:0000165 107 0.013
germ line stem cell maintenance GO:0030718 50 0.013
muscle organ development GO:0007517 127 0.013
rna 3 end processing GO:0031123 45 0.013
cellular protein complex assembly GO:0043623 71 0.013
Worm
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.013
regulation of chromosome organization GO:0033044 64 0.013
cation transport GO:0006812 110 0.013
pole plasm assembly GO:0007315 61 0.013
regulation of endopeptidase activity GO:0052548 36 0.013
cellular response to insulin stimulus GO:0032869 28 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
actin filament organization GO:0007015 126 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
locomotory behavior GO:0007626 176 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
protein localization to nucleus GO:0034504 55 0.012
positive regulation of cellular biosynthetic process GO:0031328 316 0.012
regulation of catabolic process GO:0009894 170 0.012
regulation of anatomical structure size GO:0090066 163 0.012
response to endogenous stimulus GO:0009719 119 0.012
peptidyl amino acid modification GO:0018193 105 0.012
negative regulation of proteolysis GO:0045861 31 0.012
biological adhesion GO:0022610 138 0.012
negative regulation of cell death GO:0060548 81 0.012
dendrite morphogenesis GO:0048813 199 0.012
hair cell differentiation GO:0035315 47 0.012
cell cycle checkpoint GO:0000075 95 0.012
ncrna metabolic process GO:0034660 43 0.011
somatic stem cell maintenance GO:0035019 14 0.011
protein targeting to nucleus GO:0044744 51 0.011
respiratory system development GO:0060541 213 0.011
regulation of mrna catabolic process GO:0061013 5 0.011
regulation of tor signaling GO:0032006 21 0.011
regulation of dna metabolic process GO:0051052 34 0.011
regulation of proteasomal protein catabolic process GO:0061136 39 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
meiotic cell cycle process GO:1903046 132 0.011
mitochondrial membrane organization GO:0007006 3 0.011
response to hormone GO:0009725 45 0.011
spermatid differentiation GO:0048515 114 0.011
meiotic cell cycle GO:0051321 171 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
body morphogenesis GO:0010171 2 0.011
Worm
signal transduction by phosphorylation GO:0023014 107 0.011
regulation of programmed cell death GO:0043067 152 0.010
cellular protein localization GO:0034613 160 0.010
germarium derived egg chamber formation GO:0007293 101 0.010
antimicrobial humoral response GO:0019730 99 0.010
regulation of protein complex assembly GO:0043254 42 0.010
histone modification GO:0016570 106 0.010

swm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
disease of cellular proliferation DOID:14566 0 0.032
nervous system disease DOID:863 0 0.022
cancer DOID:162 0 0.012