Drosophila melanogaster

44 known processes

Socs44A (Dmel_CG2160)

Suppressor of Cytokine Signaling at 44A

(Aliases: CG2160,dmSocs44A,socs44A,Socs44E,SOCS44A,SOCS,Dmel\CG2160)

Socs44A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived wing morphogenesis GO:0007476 337 0.202
Fly
appendage morphogenesis GO:0035107 397 0.167
Fly
establishment of localization in cell GO:0051649 402 0.140
vesicle mediated transport GO:0016192 381 0.126
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.120
neurological system process GO:0050877 358 0.117
Fly
imaginal disc derived appendage development GO:0048737 399 0.115
Fly
negative regulation of signaling GO:0023057 219 0.106
small molecule metabolic process GO:0044281 305 0.100
negative regulation of cell communication GO:0010648 223 0.091
intracellular transport GO:0046907 228 0.090
post embryonic appendage morphogenesis GO:0035120 385 0.080
Fly
organonitrogen compound metabolic process GO:1901564 318 0.080
positive regulation of cell communication GO:0010647 250 0.079
wing disc morphogenesis GO:0007472 344 0.075
Fly
phosphorylation GO:0016310 294 0.074
imaginal disc derived appendage morphogenesis GO:0035114 395 0.071
Fly
guanosine containing compound metabolic process GO:1901068 74 0.071
response to organic substance GO:0010033 284 0.070
appendage development GO:0048736 401 0.069
Fly
cellular catabolic process GO:0044248 372 0.067
Human
cellular response to chemical stimulus GO:0070887 199 0.067
endocytosis GO:0006897 310 0.067
amine metabolic process GO:0009308 12 0.065
regulation of cellular ketone metabolic process GO:0010565 3 0.065
regionalization GO:0003002 416 0.061
single organism intracellular transport GO:1902582 207 0.061
purine nucleoside triphosphate catabolic process GO:0009146 108 0.060
positive regulation of macromolecule metabolic process GO:0010604 405 0.060
regulation of cellular amine metabolic process GO:0033238 3 0.059
negative regulation of signal transduction GO:0009968 206 0.059
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.058
purine nucleoside catabolic process GO:0006152 112 0.058
cell death GO:0008219 279 0.058
positive regulation of rna biosynthetic process GO:1902680 266 0.058
negative regulation of response to stimulus GO:0048585 258 0.056
ras protein signal transduction GO:0007265 88 0.056
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.055
organic substance catabolic process GO:1901575 308 0.055
Human
single organism catabolic process GO:0044712 228 0.052
regulation of multicellular organismal development GO:2000026 414 0.052
Fly
gtp catabolic process GO:0006184 72 0.051
eye morphogenesis GO:0048592 260 0.051
Fly
small gtpase mediated signal transduction GO:0007264 88 0.050
sensory organ morphogenesis GO:0090596 260 0.049
Fly
gtp metabolic process GO:0046039 72 0.049
positive regulation of biosynthetic process GO:0009891 316 0.049
organelle assembly GO:0070925 198 0.048
negative regulation of gene expression GO:0010629 387 0.048
apoptotic process GO:0006915 159 0.047
transcription from rna polymerase ii promoter GO:0006366 368 0.047
positive regulation of response to stimulus GO:0048584 323 0.047
intracellular signal transduction GO:0035556 300 0.047
regulation of phosphorus metabolic process GO:0051174 210 0.046
death GO:0016265 284 0.046
photoreceptor cell differentiation GO:0046530 170 0.045
Fly
nucleobase containing small molecule metabolic process GO:0055086 174 0.045
regulation of cellular amino acid metabolic process GO:0006521 0 0.045
cellular amine metabolic process GO:0044106 12 0.044
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.044
guanosine containing compound catabolic process GO:1901069 74 0.043
organophosphate metabolic process GO:0019637 195 0.043
positive regulation of nucleic acid templated transcription GO:1903508 266 0.043
programmed cell death GO:0012501 257 0.043
positive regulation of signaling GO:0023056 243 0.043
catabolic process GO:0009056 409 0.043
Human
response to biotic stimulus GO:0009607 294 0.043
protein phosphorylation GO:0006468 169 0.042
nucleoside catabolic process GO:0009164 112 0.042
nucleotide catabolic process GO:0009166 109 0.041
purine ribonucleoside metabolic process GO:0046128 127 0.041
establishment or maintenance of cell polarity GO:0007163 167 0.041
muscle structure development GO:0061061 224 0.041
cellular response to endogenous stimulus GO:0071495 80 0.041
establishment of protein localization GO:0045184 163 0.040
eye development GO:0001654 323 0.040
Fly
regulation of cellular localization GO:0060341 136 0.040
regulation of organelle organization GO:0033043 196 0.040
organelle localization GO:0051640 148 0.040
compound eye development GO:0048749 307 0.040
Fly
ribonucleoside metabolic process GO:0009119 127 0.039
protein localization GO:0008104 284 0.039
compound eye morphogenesis GO:0001745 249 0.039
Fly
cellular component assembly involved in morphogenesis GO:0010927 151 0.039
aromatic compound catabolic process GO:0019439 166 0.038
tube development GO:0035295 244 0.038
carboxylic acid metabolic process GO:0019752 92 0.038
ribonucleoside triphosphate metabolic process GO:0009199 119 0.038
purine containing compound catabolic process GO:0072523 112 0.037
cellular nitrogen compound catabolic process GO:0044270 165 0.037
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.037
purine containing compound metabolic process GO:0072521 155 0.037
regulation of nervous system development GO:0051960 248 0.037
Fly
regulation of cellular component biogenesis GO:0044087 201 0.036
cellular macromolecule localization GO:0070727 220 0.036
positive regulation of signal transduction GO:0009967 223 0.036
regulation of cell differentiation GO:0045595 302 0.036
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.036
regulation of phosphate metabolic process GO:0019220 210 0.036
protein modification process GO:0036211 438 0.036
regulation of catabolic process GO:0009894 170 0.035
immune response activating signal transduction GO:0002757 2 0.034
defense response GO:0006952 300 0.034
ribonucleoside catabolic process GO:0042454 112 0.034
positive regulation of rna metabolic process GO:0051254 271 0.034
nucleoside triphosphate metabolic process GO:0009141 120 0.034
negative regulation of nucleic acid templated transcription GO:1903507 240 0.034
positive regulation of gene expression GO:0010628 290 0.034
regulation of anatomical structure morphogenesis GO:0022603 242 0.034
Fly
phagocytosis GO:0006909 215 0.034
oxoacid metabolic process GO:0043436 103 0.034
nucleoside triphosphate catabolic process GO:0009143 108 0.034
regulation of intracellular signal transduction GO:1902531 236 0.033
nucleotide metabolic process GO:0009117 161 0.033
nucleoside phosphate metabolic process GO:0006753 162 0.033
camera type eye development GO:0043010 4 0.033
purine ribonucleoside catabolic process GO:0046130 112 0.033
cellular response to organic substance GO:0071310 132 0.032
positive regulation of cellular biosynthetic process GO:0031328 316 0.032
ribose phosphate metabolic process GO:0019693 145 0.032
response to oxygen containing compound GO:1901700 200 0.031
nucleobase containing compound catabolic process GO:0034655 165 0.031
ribonucleoside triphosphate catabolic process GO:0009203 108 0.031
positive regulation of nucleotide metabolic process GO:0045981 55 0.031
glycosyl compound metabolic process GO:1901657 127 0.031
nucleoside metabolic process GO:0009116 127 0.031
cellular amino acid metabolic process GO:0006520 61 0.030
negative regulation of cellular metabolic process GO:0031324 382 0.030
organic substance transport GO:0071702 257 0.030
axon development GO:0061564 297 0.030
positive regulation of molecular function GO:0044093 136 0.030
carbohydrate derivative metabolic process GO:1901135 217 0.030
blastoderm segmentation GO:0007350 159 0.030
purine nucleoside triphosphate metabolic process GO:0009144 119 0.029
taxis GO:0042330 304 0.029
nucleoside phosphate catabolic process GO:1901292 110 0.029
microtubule based movement GO:0007018 51 0.029
regulation of gtp catabolic process GO:0033124 44 0.029
epithelial cell differentiation GO:0030855 322 0.029
Fly
single organism biosynthetic process GO:0044711 206 0.029
positive regulation of cellular component organization GO:0051130 156 0.029
purine nucleoside metabolic process GO:0042278 127 0.028
purine nucleotide metabolic process GO:0006163 146 0.028
positive regulation of gtpase activity GO:0043547 43 0.028
response to endogenous stimulus GO:0009719 119 0.028
neuromuscular junction development GO:0007528 149 0.028
organonitrogen compound catabolic process GO:1901565 128 0.028
positive regulation of gtp catabolic process GO:0033126 43 0.028
membrane organization GO:0061024 112 0.028
glycosyl compound catabolic process GO:1901658 112 0.028
regulation of cytoskeleton organization GO:0051493 89 0.028
positive regulation of phosphorus metabolic process GO:0010562 139 0.028
positive regulation of hydrolase activity GO:0051345 78 0.028
positive regulation of transcription dna templated GO:0045893 266 0.028
ribonucleotide catabolic process GO:0009261 109 0.027
regulation of molecular function GO:0065009 217 0.027
eye photoreceptor cell differentiation GO:0001754 145 0.027
Fly
organic cyclic compound catabolic process GO:1901361 168 0.027
purine ribonucleotide catabolic process GO:0009154 109 0.027
negative regulation of transcription dna templated GO:0045892 237 0.027
purine ribonucleotide metabolic process GO:0009150 145 0.027
regulation of catalytic activity GO:0050790 185 0.026
immune response regulating signaling pathway GO:0002764 2 0.026
cellular protein modification process GO:0006464 438 0.026
localization of cell GO:0051674 257 0.026
Fly
response to other organism GO:0051707 293 0.026
regulation of hydrolase activity GO:0051336 97 0.026
defense response to other organism GO:0098542 225 0.026
intracellular protein transport GO:0006886 104 0.026
axon guidance GO:0007411 233 0.026
salivary gland development GO:0007431 162 0.025
regulation of immune system process GO:0002682 176 0.025
Mouse
regulation of cell development GO:0060284 215 0.025
Fly
single organism membrane organization GO:0044802 93 0.025
cell migration GO:0016477 238 0.024
Fly
negative regulation of rna metabolic process GO:0051253 251 0.024
actin cytoskeleton organization GO:0030036 206 0.024
regulation of nucleoside metabolic process GO:0009118 50 0.024
actin filament based process GO:0030029 220 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.024
immune response GO:0006955 246 0.024
regulation of cellular catabolic process GO:0031329 157 0.024
cellular ketone metabolic process GO:0042180 24 0.024
negative regulation of biosynthetic process GO:0009890 277 0.024
columnar cuboidal epithelial cell development GO:0002066 249 0.023
Fly
synaptic transmission GO:0007268 288 0.023
protein transport GO:0015031 155 0.023
microtubule based transport GO:0010970 42 0.023
regulation of ras protein signal transduction GO:0046578 93 0.023
cellular protein localization GO:0034613 160 0.023
positive regulation of ras gtpase activity GO:0032320 36 0.023
endomembrane system organization GO:0010256 119 0.023
heterocycle catabolic process GO:0046700 166 0.023
positive regulation of cellular catabolic process GO:0031331 95 0.023
carbohydrate derivative catabolic process GO:1901136 118 0.023
purine nucleotide catabolic process GO:0006195 109 0.023
regulation of localization GO:0032879 275 0.022
positive regulation of transport GO:0051050 92 0.022
regulation of transport GO:0051049 181 0.022
regulation of cell projection organization GO:0031344 92 0.022
exocrine system development GO:0035272 162 0.022
positive regulation of nucleoside metabolic process GO:0045979 47 0.022
positive regulation of nucleotide catabolic process GO:0030813 46 0.022
macromolecular complex assembly GO:0065003 256 0.021
response to bacterium GO:0009617 198 0.021
developmental growth GO:0048589 280 0.021
regulation of small gtpase mediated signal transduction GO:0051056 93 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.021
nuclear transport GO:0051169 72 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
lateral inhibition GO:0046331 206 0.021
neuron projection guidance GO:0097485 241 0.021
establishment of organelle localization GO:0051656 122 0.021
central nervous system development GO:0007417 201 0.021
regulation of synapse organization GO:0050807 110 0.021
organophosphate catabolic process GO:0046434 112 0.021
digestive tract morphogenesis GO:0048546 127 0.020
photoreceptor cell fate commitment GO:0046552 41 0.020
Fly
somatic muscle development GO:0007525 66 0.020
response to external biotic stimulus GO:0043207 293 0.020
cytoplasmic transport GO:0016482 130 0.020
regulation of purine nucleotide metabolic process GO:1900542 62 0.020
cytoskeleton dependent intracellular transport GO:0030705 44 0.020
dendrite development GO:0016358 204 0.020
actin filament organization GO:0007015 126 0.020
single organism behavior GO:0044708 391 0.020
Fly
regulation of protein metabolic process GO:0051246 256 0.020
response to abiotic stimulus GO:0009628 341 0.020
positive regulation of catabolic process GO:0009896 105 0.019
tripartite regional subdivision GO:0007351 103 0.019
regulation of purine nucleotide catabolic process GO:0033121 48 0.019
protein complex assembly GO:0006461 200 0.019
immune system process GO:0002376 347 0.019
Mouse
chemotaxis GO:0006935 249 0.019
regulation of immune response GO:0050776 118 0.019
forebrain development GO:0030900 2 0.019
segmentation GO:0035282 207 0.019
regulation of nucleotide metabolic process GO:0006140 62 0.019
growth GO:0040007 359 0.019
Mouse
r7 cell differentiation GO:0045466 43 0.019
Fly
secretion by cell GO:0032940 101 0.019
dendrite morphogenesis GO:0048813 199 0.019
regulation of developmental growth GO:0048638 174 0.019
notch signaling pathway GO:0007219 120 0.018
regulation of phosphorylation GO:0042325 147 0.018
tissue morphogenesis GO:0048729 297 0.018
cellular lipid metabolic process GO:0044255 83 0.018
cell division GO:0051301 248 0.018
axis specification GO:0009798 167 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.018
regulation of notch signaling pathway GO:0008593 100 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
digestive tract development GO:0048565 149 0.018
muscle cell differentiation GO:0042692 103 0.018
transmembrane transport GO:0055085 139 0.018
enzyme linked receptor protein signaling pathway GO:0007167 179 0.018
regulation of nucleotide catabolic process GO:0030811 48 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.018
regulation of synapse assembly GO:0051963 94 0.017
positive regulation of protein metabolic process GO:0051247 128 0.017
sister chromatid segregation GO:0000819 92 0.017
cellular response to oxygen containing compound GO:1901701 79 0.017
synaptic growth at neuromuscular junction GO:0051124 119 0.017
epithelial cell development GO:0002064 274 0.017
Fly
regulation of cell death GO:0010941 173 0.017
positive regulation of developmental process GO:0051094 143 0.017
organic acid metabolic process GO:0006082 103 0.017
regulation of neurogenesis GO:0050767 158 0.017
Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.017
Fly
secretion GO:0046903 109 0.017
single organism cellular localization GO:1902580 180 0.017
response to radiation GO:0009314 155 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
mitotic spindle organization GO:0007052 220 0.016
synapse organization GO:0050808 196 0.016
regulation of ras gtpase activity GO:0032318 38 0.016
defense response to bacterium GO:0042742 178 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
covalent chromatin modification GO:0016569 106 0.016
endosomal transport GO:0016197 44 0.016
defense response to gram negative bacterium GO:0050829 94 0.016
gland morphogenesis GO:0022612 145 0.016
digestive system development GO:0055123 149 0.016
anterior posterior axis specification GO:0009948 109 0.016
salivary gland histolysis GO:0035070 88 0.016
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.016
Fly
protein complex biogenesis GO:0070271 201 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
kidney development GO:0001822 3 0.016
regulation of programmed cell death GO:0043067 152 0.016
negative regulation of protein metabolic process GO:0051248 85 0.015
chromosome segregation GO:0007059 157 0.015
regulation of gtpase activity GO:0043087 44 0.015
salivary gland morphogenesis GO:0007435 145 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.015
polyol biosynthetic process GO:0046173 3 0.015
regulation of mapk cascade GO:0043408 92 0.015
hindbrain development GO:0030902 2 0.015
locomotory behavior GO:0007626 176 0.015
compound eye photoreceptor cell differentiation GO:0001751 140 0.015
Fly
organic hydroxy compound metabolic process GO:1901615 83 0.015
organelle fusion GO:0048284 46 0.015
developmental programmed cell death GO:0010623 138 0.015
l amino acid import GO:0043092 2 0.015
regulation of cell morphogenesis GO:0022604 163 0.015
synapse assembly GO:0007416 143 0.015
peptidyl amino acid modification GO:0018193 105 0.014
cognition GO:0050890 141 0.014
Fly
regulation of embryonic development GO:0045995 68 0.014
erbb signaling pathway GO:0038127 58 0.014
striated muscle cell differentiation GO:0051146 90 0.014
epidermal growth factor receptor signaling pathway GO:0007173 58 0.014
leg disc development GO:0035218 92 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
tube morphogenesis GO:0035239 191 0.014
golgi vesicle transport GO:0048193 27 0.014
autophagy GO:0006914 108 0.014
homeostatic process GO:0042592 199 0.014
chorion containing eggshell formation GO:0007304 105 0.014
regulation of protein localization GO:0032880 76 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
cation transport GO:0006812 110 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
rna processing GO:0006396 147 0.014
nucleocytoplasmic transport GO:0006913 72 0.013
rho protein signal transduction GO:0007266 14 0.013
lipid metabolic process GO:0006629 121 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
regulation of organ morphogenesis GO:2000027 78 0.013
Fly
developmental maturation GO:0021700 172 0.013
embryonic morphogenesis GO:0048598 206 0.013
mrna metabolic process GO:0016071 124 0.013
nuclear division GO:0000280 332 0.013
negative regulation of nervous system development GO:0051961 92 0.013
Fly
regulation of epithelial cell proliferation GO:0050678 4 0.013
gland development GO:0048732 191 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
cilium assembly GO:0042384 38 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
regulation of apoptotic process GO:0042981 130 0.013
regulation of proteolysis GO:0030162 87 0.013
positive regulation of phosphorylation GO:0042327 87 0.013
negative regulation of phosphorus metabolic process GO:0010563 45 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
positive regulation of apoptotic signaling pathway GO:2001235 4 0.013
embryonic pattern specification GO:0009880 174 0.013
tissue death GO:0016271 102 0.013
positive regulation of developmental growth GO:0048639 62 0.013
adult behavior GO:0030534 137 0.013
chromatin organization GO:0006325 207 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
response to lipopolysaccharide GO:0032496 4 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.012
smoothened signaling pathway GO:0007224 49 0.012
anterior posterior pattern specification GO:0009952 136 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
myotube cell development GO:0014904 3 0.012
stem cell division GO:0017145 69 0.012
organelle fission GO:0048285 340 0.012
cell motility GO:0048870 251 0.012
Fly
regulation of protein transport GO:0051223 57 0.012
body morphogenesis GO:0010171 2 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
connective tissue development GO:0061448 3 0.012
peptidyl threonine phosphorylation GO:0018107 2 0.012
protein localization to organelle GO:0033365 82 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
regulation of synapse structure and activity GO:0050803 128 0.012
cell projection assembly GO:0030031 94 0.011
jak stat cascade GO:0007259 49 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
positive regulation of cell projection organization GO:0031346 29 0.011
response to nitrogen compound GO:1901698 90 0.011
centrosome organization GO:0051297 163 0.011
regulation of response to stress GO:0080134 200 0.011
macromolecule catabolic process GO:0009057 161 0.011
Human
regulation of protein phosphorylation GO:0001932 64 0.011
mitotic nuclear division GO:0007067 213 0.011
cellular response to growth factor stimulus GO:0071363 30 0.011
cilium organization GO:0044782 41 0.011
microtubule organizing center organization GO:0031023 168 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
regulation of intracellular transport GO:0032386 64 0.011
spindle organization GO:0007051 253 0.011
chaeta development GO:0022416 97 0.011
autophagic cell death GO:0048102 83 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
pigment metabolic process GO:0042440 84 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
Human
axon cargo transport GO:0008088 29 0.011
brain development GO:0007420 120 0.011
imaginal disc derived wing vein specification GO:0007474 48 0.011
regulation of neuron differentiation GO:0045664 103 0.011
Fly
cellular response to molecule of bacterial origin GO:0071219 3 0.011
myotube differentiation GO:0014902 46 0.011
response to extracellular stimulus GO:0009991 116 0.011
axonogenesis GO:0007409 290 0.010
regulation of actin filament based process GO:0032970 42 0.010
eye photoreceptor cell fate commitment GO:0042706 37 0.010
Fly
histolysis GO:0007559 102 0.010
negative regulation of phosphorylation GO:0042326 35 0.010
memory GO:0007613 94 0.010
Fly
response to glucose GO:0009749 2 0.010
golgi organization GO:0007030 66 0.010
cell proliferation GO:0008283 299 0.010
wnt signaling pathway GO:0016055 98 0.010
proteolysis GO:0006508 192 0.010
Human
protein heterooligomerization GO:0051291 4 0.010
regulation of cell shape GO:0008360 113 0.010
regulation of neuron projection development GO:0010975 69 0.010
protein maturation GO:0051604 71 0.010
gastrulation GO:0007369 70 0.010

Socs44A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.021
nervous system disease DOID:863 0 0.020
sensory system disease DOID:0050155 0 0.016
cardiovascular system disease DOID:1287 0 0.011
eye and adnexa disease DOID:1492 0 0.010
disease of metabolism DOID:0014667 0 0.010