Drosophila melanogaster

194 known processes

lola (Dmel_CG12052)

longitudinals lacking

(Aliases: sw59,Lola,eyeful,CG18381,CG18380,l(2)00642,NEST:bs06a08,BtbIV,BEST:LD03274,CG18378,CG18379,CG18376,l(2)s3697,CG12052,bs06a08.y1,BcDNA:RH31485,BTB-IV,LD03274,CG30013,CG30012,CG30014,BcDNA:LD17006,Dmel\CG12052)

lola biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dendrite development GO:0016358 204 1.000
neuron projection guidance GO:0097485 241 1.000
axon development GO:0061564 297 1.000
dendrite morphogenesis GO:0048813 199 1.000
axon guidance GO:0007411 233 1.000
axonogenesis GO:0007409 290 0.999
dendrite guidance GO:0070983 21 0.998
regulation of imaginal disc derived wing size GO:0044719 20 0.998
regulation of multicellular organismal development GO:2000026 414 0.997
Fly
axon midline choice point recognition GO:0016199 26 0.996
positive regulation of rna metabolic process GO:0051254 271 0.995
Fly
appendage development GO:0048736 401 0.992
positive regulation of gene expression GO:0010628 290 0.990
Fly
positive regulation of biosynthetic process GO:0009891 316 0.988
Fly
chemotaxis GO:0006935 249 0.988
positive regulation of macromolecule metabolic process GO:0010604 405 0.985
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.982
Fly
head development GO:0060322 135 0.979
axon choice point recognition GO:0016198 26 0.960
regulation of dendrite morphogenesis GO:0048814 28 0.959
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.948
Fly
taxis GO:0042330 304 0.939
morphogenesis of an epithelium GO:0002009 276 0.934
transcription from rna polymerase ii promoter GO:0006366 368 0.923
Fly
death GO:0016265 284 0.914
post embryonic appendage morphogenesis GO:0035120 385 0.909
anterior posterior pattern specification GO:0009952 136 0.906
Fly
brain development GO:0007420 120 0.902
multi organism behavior GO:0051705 175 0.897
neuron recognition GO:0008038 101 0.897
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.892
Fly
tube development GO:0035295 244 0.867
Fly
positive regulation of nucleic acid templated transcription GO:1903508 266 0.862
Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.857
Fly
segmentation GO:0035282 207 0.855
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.845
Fly
regionalization GO:0003002 416 0.842
Fly
synapse organization GO:0050808 196 0.836
positive regulation of transcription dna templated GO:0045893 266 0.831
Fly
appendage morphogenesis GO:0035107 397 0.829
eye development GO:0001654 323 0.826
dorsal ventral axon guidance GO:0033563 2 0.819
branching morphogenesis of an epithelial tube GO:0048754 45 0.805
Fly
sex differentiation GO:0007548 81 0.800
regulation of nervous system development GO:0051960 248 0.795
negative regulation of transcription dna templated GO:0045892 237 0.795
Fly
photoreceptor cell axon guidance GO:0072499 23 0.783
regulation of cell differentiation GO:0045595 302 0.781
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.772
Fly
synapse assembly GO:0007416 143 0.770
chaeta development GO:0022416 97 0.735
r7 cell differentiation GO:0045466 43 0.733
negative regulation of cellular biosynthetic process GO:0031327 277 0.711
Fly
anterior posterior axis specification embryo GO:0008595 103 0.707
Fly
single organism behavior GO:0044708 391 0.705
Fly
regulation of dendrite development GO:0050773 37 0.704
positive regulation of multicellular organismal process GO:0051240 143 0.697
mushroom body development GO:0016319 70 0.681
regulation of cell development GO:0060284 215 0.660
imaginal disc derived wing morphogenesis GO:0007476 337 0.656
tissue morphogenesis GO:0048729 297 0.653
central nervous system development GO:0007417 201 0.646
imaginal disc derived appendage morphogenesis GO:0035114 395 0.617
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.614
Fly
regulation of gene expression epigenetic GO:0040029 128 0.607
Fly
response to abiotic stimulus GO:0009628 341 0.595
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.591
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.576
Fly
developmental growth GO:0048589 280 0.575
Fly
growth GO:0040007 359 0.553
Fly
gonad development GO:0008406 50 0.545
embryonic pattern specification GO:0009880 174 0.544
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.531
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.527
Fly
blastoderm segmentation GO:0007350 159 0.518
Fly
imaginal disc derived appendage development GO:0048737 399 0.517
regulation of neuron projection development GO:0010975 69 0.514
morphogenesis of a branching structure GO:0001763 45 0.495
Fly
axis specification GO:0009798 167 0.486
Fly
tripartite regional subdivision GO:0007351 103 0.463
Fly
negative regulation of biosynthetic process GO:0009890 277 0.457
Fly
endocytosis GO:0006897 310 0.438
glial cell migration GO:0008347 31 0.427
reproductive system development GO:0061458 74 0.427
synaptic growth at neuromuscular junction GO:0051124 119 0.419
cell recognition GO:0008037 102 0.418
salivary gland development GO:0007431 162 0.415
Fly
forebrain development GO:0030900 2 0.403
regulation of embryonic development GO:0045995 68 0.360
Fly
epithelial cell migration GO:0010631 148 0.345
Fly
regulation of photoreceptor cell axon guidance GO:2000289 5 0.341
cell motility GO:0048870 251 0.340
Fly
aggressive behavior GO:0002118 63 0.330
epithelial cell development GO:0002064 274 0.329
Fly
rna localization GO:0006403 115 0.328
regulation of anatomical structure morphogenesis GO:0022603 242 0.324
Fly
muscle structure development GO:0061061 224 0.320
Fly
regulation of cellular component biogenesis GO:0044087 201 0.312
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.308
Fly
regulation of programmed cell death GO:0043067 152 0.304
actin filament based process GO:0030029 220 0.300
olfactory bulb axon guidance GO:0071678 3 0.292
neurological system process GO:0050877 358 0.291
wing disc morphogenesis GO:0007472 344 0.289
circadian rhythm GO:0007623 105 0.282
protein complex assembly GO:0006461 200 0.280
Fly
striated muscle cell differentiation GO:0051146 90 0.274
Fly
regulation of neurogenesis GO:0050767 158 0.272
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.251
Fly
neuromuscular junction development GO:0007528 149 0.248
morphogenesis of a branching epithelium GO:0061138 45 0.232
Fly
regulation of synapse assembly GO:0051963 94 0.224
cell death GO:0008219 279 0.224
negative regulation of neurogenesis GO:0050768 53 0.221
reproductive structure development GO:0048608 74 0.220
morphogenesis of embryonic epithelium GO:0016331 94 0.219
Fly
posttranscriptional regulation of gene expression GO:0010608 145 0.211
regulation of embryonic cell shape GO:0016476 30 0.208
Fly
actin cytoskeleton organization GO:0030036 206 0.202
programmed cell death GO:0012501 257 0.199
axon extension involved in axon guidance GO:0048846 10 0.198
development of primary sexual characteristics GO:0045137 50 0.192
imaginal disc pattern formation GO:0007447 91 0.188
negative regulation of rna metabolic process GO:0051253 251 0.179
Fly
mating GO:0007618 120 0.178
cell maturation GO:0048469 144 0.169
embryonic axis specification GO:0000578 107 0.168
Fly
pole plasm mrna localization GO:0019094 49 0.162
skeletal muscle organ development GO:0060538 48 0.153
cell migration GO:0016477 238 0.151
Fly
positive regulation of developmental process GO:0051094 143 0.146
developmental programmed cell death GO:0010623 138 0.142
learning or memory GO:0007611 141 0.136
gene silencing GO:0016458 138 0.135
Fly
ameboidal type cell migration GO:0001667 151 0.133
Fly
regulation of phosphatase activity GO:0010921 3 0.130
multicellular organismal reproductive behavior GO:0033057 110 0.127
apoptotic process GO:0006915 159 0.124
ribonucleoprotein complex biogenesis GO:0022613 31 0.121
germ cell migration GO:0008354 43 0.120
Fly
negative regulation of nucleic acid templated transcription GO:1903507 240 0.117
Fly
larval development GO:0002164 104 0.116
positive regulation of neurogenesis GO:0050769 41 0.115
negative regulation of gene expression GO:0010629 387 0.114
Fly
olfactory behavior GO:0042048 97 0.112
Fly
eye morphogenesis GO:0048592 260 0.111
posttranscriptional gene silencing by rna GO:0035194 45 0.109
response to inorganic substance GO:0010035 44 0.103
dorsal ventral pattern formation GO:0009953 133 0.102
tube morphogenesis GO:0035239 191 0.101
Fly
regulation of synapse organization GO:0050807 110 0.099
response to external biotic stimulus GO:0043207 293 0.098
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.098
Fly
nucleus localization GO:0051647 34 0.097
embryo development ending in birth or egg hatching GO:0009792 152 0.097
Fly
positive regulation of developmental growth GO:0048639 62 0.091
ovarian follicle cell development GO:0030707 248 0.090
Fly
regulation of protein metabolic process GO:0051246 256 0.090
neuron projection extension GO:1990138 32 0.089
semaphorin plexin signaling pathway GO:0071526 4 0.088
dna conformation change GO:0071103 105 0.087
Fly
negative regulation of developmental process GO:0051093 201 0.086
exocrine system development GO:0035272 162 0.085
Fly
negative regulation of rna biosynthetic process GO:1902679 240 0.085
Fly
epithelial tube morphogenesis GO:0060562 88 0.083
Fly
negative regulation of cell development GO:0010721 62 0.083
phagocytosis GO:0006909 215 0.081
regulation of cell shape GO:0008360 113 0.080
Fly
retinal ganglion cell axon guidance GO:0031290 12 0.079
response to lipopolysaccharide GO:0032496 4 0.078
protein modification process GO:0036211 438 0.074
cell cycle phase transition GO:0044770 140 0.072
stem cell differentiation GO:0048863 117 0.072
cellular macromolecular complex assembly GO:0034622 153 0.070
positive regulation of signaling GO:0023056 243 0.066
microtubule based movement GO:0007018 51 0.066
response to gravity GO:0009629 26 0.065
Fly
regulation of apoptotic process GO:0042981 130 0.064
positive regulation of axonogenesis GO:0050772 2 0.062
branching involved in open tracheal system development GO:0060446 45 0.061
Fly
enzyme linked receptor protein signaling pathway GO:0007167 179 0.061
organelle fission GO:0048285 340 0.060
Fly
stem cell development GO:0048864 79 0.060
reproductive behavior GO:0019098 122 0.059
regulation of glial cell proliferation GO:0060251 11 0.059
chemosensory behavior GO:0007635 106 0.058
Fly
columnar cuboidal epithelial cell development GO:0002066 249 0.057
Fly
cellular response to dna damage stimulus GO:0006974 223 0.057
positive regulation of response to stimulus GO:0048584 323 0.056
developmental growth involved in morphogenesis GO:0060560 65 0.055
Fly
translation GO:0006412 69 0.054
regulation of cell morphogenesis GO:0022604 163 0.054
Fly
positive regulation of cellular component organization GO:0051130 156 0.054
regulation of malpighian tubule diameter GO:0035297 3 0.054
Fly
regulation of localization GO:0032879 275 0.053
response to lipid GO:0033993 38 0.053
Fly
oocyte development GO:0048599 124 0.053
cell fate determination GO:0001709 91 0.052
organic acid metabolic process GO:0006082 103 0.052
embryonic development via the syncytial blastoderm GO:0001700 148 0.052
Fly
gene silencing by rna GO:0031047 57 0.051
genitalia development GO:0048806 26 0.051
Fly
negative regulation of epithelial cell migration GO:0010633 1 0.049
regulation of organ morphogenesis GO:2000027 78 0.048
Fly
organ formation GO:0048645 39 0.048
male mating behavior GO:0060179 70 0.047
heart development GO:0007507 82 0.047
regulation of gene silencing GO:0060968 63 0.046
Fly
locomotory behavior GO:0007626 176 0.045
substrate dependent cell migration GO:0006929 3 0.045
negative regulation of nervous system development GO:0051961 92 0.044
male courtship behavior GO:0008049 63 0.043
embryonic heart tube development GO:0035050 22 0.043
response to hypoxia GO:0001666 53 0.042
response to metal ion GO:0010038 23 0.042
dosage compensation GO:0007549 16 0.039
Fly
telencephalon development GO:0021537 2 0.039
positive regulation of axon extension GO:0045773 2 0.039
compound eye development GO:0048749 307 0.038
courtship behavior GO:0007619 68 0.038
dorsal appendage formation GO:0046843 47 0.037
Fly
negative regulation of cell death GO:0060548 81 0.037
intracellular signal transduction GO:0035556 300 0.036
carboxylic acid metabolic process GO:0019752 92 0.036
central nervous system projection neuron axonogenesis GO:0021952 6 0.035
positive regulation of cellular component biogenesis GO:0044089 80 0.034
positive regulation of cell differentiation GO:0045597 64 0.034
axonal fasciculation GO:0007413 12 0.034
negative regulation of cell differentiation GO:0045596 143 0.034
regulation of intracellular signal transduction GO:1902531 236 0.033
positive regulation of axon guidance GO:1902669 1 0.033
oocyte anterior posterior axis specification GO:0007314 72 0.032
organic hydroxy compound metabolic process GO:1901615 83 0.032
motor neuron axon guidance GO:0008045 58 0.032
regulation of translation GO:0006417 56 0.032
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.032
positive regulation of cell growth GO:0030307 19 0.032
regulation of mitotic cell cycle phase transition GO:1901990 130 0.031
regulation of axon extension involved in axon guidance GO:0048841 4 0.031
cardiac cell fate commitment GO:0060911 17 0.031
organic substance catabolic process GO:1901575 308 0.031
nucleobase containing compound catabolic process GO:0034655 165 0.030
response to organic substance GO:0010033 284 0.030
Fly
neuromuscular process GO:0050905 21 0.030
immune response GO:0006955 246 0.030
regulation of neuron differentiation GO:0045664 103 0.030
response to growth factor GO:0070848 31 0.029
synaptic target recognition GO:0008039 45 0.029
regulation of cell projection organization GO:0031344 92 0.029
biological adhesion GO:0022610 138 0.029
positive regulation of cell death GO:0010942 69 0.028
gland morphogenesis GO:0022612 145 0.028
Fly
regulation of cell death GO:0010941 173 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.028
organelle localization GO:0051640 148 0.028
regulation of synapse structure and activity GO:0050803 128 0.027
muscle organ development GO:0007517 127 0.027
cell fate specification GO:0001708 71 0.027
Fly
neuron remodeling GO:0016322 29 0.027
muscle cell development GO:0055001 50 0.027
Fly
axon extension GO:0048675 32 0.027
cell growth GO:0016049 108 0.027
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.027
lipid homeostasis GO:0055088 33 0.026
cell projection assembly GO:0030031 94 0.026
circulatory system development GO:0072359 82 0.026
maternal determination of anterior posterior axis embryo GO:0008358 74 0.025
posttranscriptional gene silencing GO:0016441 46 0.025
positive regulation of protein metabolic process GO:0051247 128 0.025
dna damage checkpoint GO:0000077 78 0.025
cellular response to oxygen containing compound GO:1901701 79 0.025
Fly
wnt signaling pathway GO:0016055 98 0.024
gland development GO:0048732 191 0.024
Fly
chorion containing eggshell formation GO:0007304 105 0.024
Fly
chromosome segregation GO:0007059 157 0.024
Fly
organelle inheritance GO:0048308 2 0.024
rhythmic process GO:0048511 106 0.024
regulation of wnt signaling pathway GO:0030111 68 0.024
regulation of hemocyte proliferation GO:0035206 37 0.024
mrna metabolic process GO:0016071 124 0.024
negative regulation of multicellular organismal process GO:0051241 142 0.024
macromolecular complex assembly GO:0065003 256 0.024
Fly
filopodium assembly GO:0046847 33 0.023
oxoacid metabolic process GO:0043436 103 0.023
gliogenesis GO:0042063 80 0.023
germarium derived oocyte fate determination GO:0007294 26 0.023
mating behavior GO:0007617 106 0.023
positive regulation of protein complex assembly GO:0031334 22 0.023
actin filament organization GO:0007015 126 0.022
compound eye photoreceptor cell differentiation GO:0001751 140 0.022
establishment of organelle localization GO:0051656 122 0.022
actin cytoskeleton reorganization GO:0031532 22 0.022
development of primary female sexual characteristics GO:0046545 12 0.022
negative regulation of cell cycle process GO:0010948 109 0.021
positive regulation of cell communication GO:0010647 250 0.021
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.021
response to endogenous stimulus GO:0009719 119 0.021
negative regulation of cellular component organization GO:0051129 108 0.021
central nervous system neuron axonogenesis GO:0021955 7 0.021
mitotic dna integrity checkpoint GO:0044774 75 0.021
oocyte axis specification GO:0007309 108 0.020
response to alcohol GO:0097305 95 0.020
Fly
epithelial cell differentiation GO:0030855 322 0.020
Fly
specification of symmetry GO:0009799 13 0.019
positive regulation of nervous system development GO:0051962 69 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
axon cargo transport GO:0008088 29 0.019
protein destabilization GO:0031648 2 0.019
muscle cell migration GO:0014812 3 0.019
cardiovascular system development GO:0072358 82 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.019
regulation of cell substrate adhesion GO:0010810 2 0.019
nephron tubule development GO:0072080 3 0.019
positive regulation of endopeptidase activity GO:0010950 26 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
brain morphogenesis GO:0048854 16 0.018
hematopoietic stem cell differentiation GO:0060218 1 0.017
histolysis GO:0007559 102 0.017
Fly
response to decreased oxygen levels GO:0036293 58 0.017
cellular response to organic substance GO:0071310 132 0.017
Fly
anterior posterior axis specification GO:0009948 109 0.017
Fly
positive regulation of neuron differentiation GO:0045666 26 0.017
chromosome organization GO:0051276 360 0.017
Fly
response to light stimulus GO:0009416 124 0.017
regulation of chromosome organization GO:0033044 64 0.016
Fly
negative regulation of gene expression epigenetic GO:0045814 77 0.016
Fly
response to osmotic stress GO:0006970 14 0.016
regulation of proteolysis GO:0030162 87 0.016
mesodermal cell migration GO:0008078 7 0.016
pole plasm oskar mrna localization GO:0045451 46 0.016
developmental maturation GO:0021700 172 0.016
mesenchymal cell development GO:0014031 1 0.015
regulation of growth GO:0040008 233 0.015
dna packaging GO:0006323 91 0.015
Fly
regulation of phosphoprotein phosphatase activity GO:0043666 3 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
positive regulation of signal transduction GO:0009967 223 0.015
semaphorin plexin signaling pathway involved in regulation of photoreceptor cell axon guidance GO:2000305 2 0.015
actin polymerization or depolymerization GO:0008154 31 0.015
connective tissue development GO:0061448 3 0.015
cell cycle g1 s phase transition GO:0044843 31 0.015
positive regulation of cell development GO:0010720 61 0.015
multi organism reproductive behavior GO:0044705 121 0.014
branch fusion open tracheal system GO:0035147 17 0.014
Fly
organophosphate catabolic process GO:0046434 112 0.014
body morphogenesis GO:0010171 2 0.014
rna processing GO:0006396 147 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.014
response to bacterium GO:0009617 198 0.014
ribonucleotide catabolic process GO:0009261 109 0.014
oocyte differentiation GO:0009994 145 0.013
cell cell adhesion GO:0098609 26 0.013
outflow tract morphogenesis GO:0003151 4 0.013
immune system process GO:0002376 347 0.013
regulation of cell fate commitment GO:0010453 29 0.013
Fly
photoreceptor cell development GO:0042461 96 0.013
spinal cord development GO:0021510 1 0.013
central complex development GO:0048036 9 0.013
cardiac cell fate specification GO:0060912 10 0.013
neuroblast development GO:0014019 13 0.013
compound eye photoreceptor development GO:0042051 78 0.013
wing disc pattern formation GO:0035222 66 0.013
regulation of response to stress GO:0080134 200 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
regulation of protein complex assembly GO:0043254 42 0.013
cell proliferation GO:0008283 299 0.012
leg disc development GO:0035218 92 0.012
cellular amine metabolic process GO:0044106 12 0.012
regulation of nurse cell apoptotic process GO:0045477 9 0.012
negative regulation of apoptotic process GO:0043066 63 0.012
positive regulation of neuron projection development GO:0010976 14 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
multi multicellular organism process GO:0044706 123 0.012
response to hormone GO:0009725 45 0.012
cellular catabolic process GO:0044248 372 0.012
Fly
chromatin assembly GO:0031497 48 0.012
Fly
oocyte construction GO:0007308 112 0.012
compound eye morphogenesis GO:0001745 249 0.012
cellular protein modification process GO:0006464 438 0.012
positive regulation of organelle organization GO:0010638 65 0.011
cell cycle checkpoint GO:0000075 95 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
Fly
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.011
g1 s transition of mitotic cell cycle GO:0000082 31 0.011
rna transport GO:0050658 46 0.011
histone h3 k9 modification GO:0061647 12 0.011
positive regulation of cell projection organization GO:0031346 29 0.011
negative regulation of neuroblast proliferation GO:0007406 27 0.011
organophosphate metabolic process GO:0019637 195 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
response to other organism GO:0051707 293 0.011
male sex differentiation GO:0046661 25 0.010
Fly
embryonic morphogenesis GO:0048598 206 0.010
Fly
nuclear division GO:0000280 332 0.010
Fly
response to oxygen containing compound GO:1901700 200 0.010
Fly

lola disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org