Drosophila melanogaster

40 known processes

Gapdh1 (Dmel_CG12055)

Glyceraldehyde 3 phosphate dehydrogenase 1

(Aliases: Gapdh-1,Gapd,GADPH,GAPDH I,CG12055,GAPDH-1,BEST:GH12586,GAPDH,GAP,gapdh,Dmel\CG12055,gapdh-1,GA3PDH,Gapdh43E,Gapdh,gh12586,gadph)

Gapdh1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
myoblast fusion GO:0007520 43 0.797
nad metabolic process GO:0019674 1 0.691
syncytium formation by plasma membrane fusion GO:0000768 43 0.526
syncytium formation GO:0006949 43 0.502
nucleotide metabolic process GO:0009117 161 0.447
muscle structure development GO:0061061 224 0.419
organophosphate metabolic process GO:0019637 195 0.404
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.363
purine nucleoside metabolic process GO:0042278 127 0.361
nucleobase containing small molecule metabolic process GO:0055086 174 0.357
generation of precursor metabolites and energy GO:0006091 42 0.346
somatic muscle development GO:0007525 66 0.337
nicotinamide nucleotide metabolic process GO:0046496 2 0.313
muscle cell differentiation GO:0042692 103 0.302
pyruvate metabolic process GO:0006090 7 0.300
small molecule metabolic process GO:0044281 305 0.267
nucleoside metabolic process GO:0009116 127 0.261
oxidation reduction process GO:0055114 123 0.258
cellular component assembly involved in morphogenesis GO:0010927 151 0.254
oxoacid metabolic process GO:0043436 103 0.245
catabolic process GO:0009056 409 0.241
organonitrogen compound metabolic process GO:1901564 318 0.235
nucleoside phosphate metabolic process GO:0006753 162 0.233
carboxylic acid metabolic process GO:0019752 92 0.231
ribose phosphate metabolic process GO:0019693 145 0.204
response to metal ion GO:0010038 23 0.199
protein complex assembly GO:0006461 200 0.197
purine ribonucleoside metabolic process GO:0046128 127 0.196
nucleoside triphosphate metabolic process GO:0009141 120 0.196
purine nucleoside triphosphate metabolic process GO:0009144 119 0.188
response to hexose GO:0009746 3 0.172
ribonucleotide metabolic process GO:0009259 145 0.166
purine nucleotide metabolic process GO:0006163 146 0.156
response to organic substance GO:0010033 284 0.146
Human
regulation of cell differentiation GO:0045595 302 0.145
phosphorylation GO:0016310 294 0.132
organic substance catabolic process GO:1901575 308 0.125
organic acid metabolic process GO:0006082 103 0.115
atp metabolic process GO:0046034 49 0.113
larval development GO:0002164 104 0.112
Worm
nucleoside monophosphate metabolic process GO:0009123 52 0.107
cellular protein complex assembly GO:0043623 71 0.103
ribonucleoside metabolic process GO:0009119 127 0.093
carbohydrate metabolic process GO:0005975 82 0.091
carbohydrate derivative metabolic process GO:1901135 217 0.090
embryo development ending in birth or egg hatching GO:0009792 152 0.090
Worm
regulation of multicellular organismal development GO:2000026 414 0.085
ribonucleoside triphosphate metabolic process GO:0009199 119 0.083
purine containing compound metabolic process GO:0072521 155 0.083
macromolecular complex assembly GO:0065003 256 0.083
cellular macromolecular complex assembly GO:0034622 153 0.082
purine nucleoside monophosphate metabolic process GO:0009126 50 0.081
protein complex biogenesis GO:0070271 201 0.077
response to monosaccharide GO:0034284 4 0.073
response to oxygen containing compound GO:1901700 200 0.072
ribonucleoside biosynthetic process GO:0042455 3 0.072
ribonucleoside monophosphate metabolic process GO:0009161 51 0.071
spermatogenesis GO:0007283 200 0.071
response to organic cyclic compound GO:0014070 89 0.071
single organism catabolic process GO:0044712 228 0.070
purine ribonucleoside catabolic process GO:0046130 112 0.069
regulation of phosphorus metabolic process GO:0051174 210 0.067
response to inorganic substance GO:0010035 44 0.067
cellular response to chemical stimulus GO:0070887 199 0.067
Human
synapse assembly GO:0007416 143 0.066
glycolytic process GO:0006096 6 0.064
glycosyl compound catabolic process GO:1901658 112 0.063
negative regulation of stem cell proliferation GO:2000647 30 0.063
developmental growth GO:0048589 280 0.063
Worm
response to organophosphorus GO:0046683 2 0.063
single organism intracellular transport GO:1902582 207 0.060
response to nitrogen compound GO:1901698 90 0.059
actin cytoskeleton organization GO:0030036 206 0.057
response to endogenous stimulus GO:0009719 119 0.057
nadh metabolic process GO:0006734 1 0.057
atp biosynthetic process GO:0006754 2 0.056
glycosyl compound metabolic process GO:1901657 127 0.054
ribose phosphate biosynthetic process GO:0046390 28 0.053
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.052
oxidative phosphorylation GO:0006119 9 0.052
immune response GO:0006955 246 0.052
Human
regulation of cell proliferation GO:0042127 163 0.052
response to glucose GO:0009749 2 0.051
cell motility GO:0048870 251 0.050
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.050
nucleoside monophosphate biosynthetic process GO:0009124 4 0.050
purine nucleoside biosynthetic process GO:0042451 3 0.048
cellular catabolic process GO:0044248 372 0.047
determination of adult lifespan GO:0008340 137 0.045
Worm
response to oxidative stress GO:0006979 86 0.045
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.045
nucleotide biosynthetic process GO:0009165 34 0.045
myotube differentiation GO:0014902 46 0.044
regulation of phosphate metabolic process GO:0019220 210 0.042
response to external biotic stimulus GO:0043207 293 0.041
striated muscle myosin thick filament assembly GO:0071688 3 0.041
carbohydrate derivative biosynthetic process GO:1901137 85 0.041
nucleoside triphosphate catabolic process GO:0009143 108 0.041
striated muscle cell differentiation GO:0051146 90 0.040
multicellular organismal aging GO:0010259 140 0.040
Worm
gland development GO:0048732 191 0.039
homeostatic process GO:0042592 199 0.038
aromatic compound catabolic process GO:0019439 166 0.038
regulation of cell death GO:0010941 173 0.038
oxidoreduction coenzyme metabolic process GO:0006733 2 0.036
energy derivation by oxidation of organic compounds GO:0015980 32 0.036
negative regulation of neural precursor cell proliferation GO:2000178 27 0.036
programmed cell death GO:0012501 257 0.036
single organism carbohydrate metabolic process GO:0044723 72 0.035
death GO:0016265 284 0.035
lateral inhibition GO:0046331 206 0.035
negative regulation of multicellular organismal process GO:0051241 142 0.035
biological adhesion GO:0022610 138 0.034
cell migration GO:0016477 238 0.034
regulation of anatomical structure morphogenesis GO:0022603 242 0.033
response to heat GO:0009408 63 0.033
myofibril assembly GO:0030239 36 0.032
anatomical structure homeostasis GO:0060249 97 0.032
organelle assembly GO:0070925 198 0.032
purine ribonucleotide catabolic process GO:0009154 109 0.031
heterocycle catabolic process GO:0046700 166 0.031
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.031
regulation of programmed cell death GO:0043067 152 0.031
response to decreased oxygen levels GO:0036293 58 0.031
endocytosis GO:0006897 310 0.031
nucleoside catabolic process GO:0009164 112 0.031
pyridine containing compound metabolic process GO:0072524 3 0.031
response to organonitrogen compound GO:0010243 75 0.030
regulation of molecular function GO:0065009 217 0.030
regulation of nervous system development GO:0051960 248 0.030
ribonucleoside catabolic process GO:0042454 112 0.030
embryonic morphogenesis GO:0048598 206 0.029
muscle system process GO:0003012 21 0.029
response to hypoxia GO:0001666 53 0.029
organonitrogen compound biosynthetic process GO:1901566 117 0.029
nucleobase containing compound catabolic process GO:0034655 165 0.029
protein modification process GO:0036211 438 0.029
positive regulation of cell proliferation GO:0008284 47 0.028
defense response GO:0006952 300 0.027
Human
regulation of protein metabolic process GO:0051246 256 0.027
Human
apoptotic process GO:0006915 159 0.027
negative regulation of developmental process GO:0051093 201 0.027
purine ribonucleotide metabolic process GO:0009150 145 0.027
response to purine containing compound GO:0014074 12 0.027
aging GO:0007568 143 0.026
Worm
reproductive system development GO:0061458 74 0.025
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.025
ribonucleoside triphosphate catabolic process GO:0009203 108 0.024
response to nutrient levels GO:0031667 114 0.024
cellular protein modification process GO:0006464 438 0.024
cellular ketone metabolic process GO:0042180 24 0.024
organonitrogen compound catabolic process GO:1901565 128 0.024
response to abiotic stimulus GO:0009628 341 0.023
carbohydrate catabolic process GO:0016052 7 0.023
glycosyl compound biosynthetic process GO:1901659 3 0.023
regulation of apoptotic process GO:0042981 130 0.023
response to oxygen levels GO:0070482 59 0.023
single organism biosynthetic process GO:0044711 206 0.022
regulation of catabolic process GO:0009894 170 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
striated muscle cell development GO:0055002 50 0.021
negative regulation of organelle organization GO:0010639 56 0.021
growth GO:0040007 359 0.021
Worm
g protein coupled receptor signaling pathway GO:0007186 136 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
response to wounding GO:0009611 94 0.021
purine nucleotide catabolic process GO:0006195 109 0.021
tissue morphogenesis GO:0048729 297 0.021
male gamete generation GO:0048232 201 0.021
regulation of cell morphogenesis GO:0022604 163 0.020
chaeta development GO:0022416 97 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
cellular macromolecule localization GO:0070727 220 0.020
positive regulation of programmed cell death GO:0043068 62 0.020
monocarboxylic acid metabolic process GO:0032787 29 0.020
ribonucleoside monophosphate biosynthetic process GO:0009156 3 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
negative regulation of neurogenesis GO:0050768 53 0.019
regulation of myotube differentiation GO:0010830 6 0.019
purine containing compound catabolic process GO:0072523 112 0.019
regulation of cell cycle GO:0051726 291 0.019
regulation of cell development GO:0060284 215 0.018
electron transport chain GO:0022900 14 0.018
nucleoside phosphate biosynthetic process GO:1901293 34 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
vesicle mediated transport GO:0016192 381 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
regulation of organelle organization GO:0033043 196 0.018
organophosphate catabolic process GO:0046434 112 0.018
cell adhesion GO:0007155 136 0.018
spermatid differentiation GO:0048515 114 0.018
regulation of growth GO:0040008 233 0.018
Worm
regulation of cytoskeleton organization GO:0051493 89 0.018
carbohydrate derivative catabolic process GO:1901136 118 0.018
regulation of nucleotide metabolic process GO:0006140 62 0.017
protein phosphorylation GO:0006468 169 0.017
cell death GO:0008219 279 0.017
negative regulation of gene expression GO:0010629 387 0.017
Human
positive regulation of nucleotide metabolic process GO:0045981 55 0.017
response to gravity GO:0009629 26 0.017
body morphogenesis GO:0010171 2 0.016
cellular response to peptide GO:1901653 28 0.016
regulation of immune system process GO:0002682 176 0.016
regulation of catalytic activity GO:0050790 185 0.016
central nervous system development GO:0007417 201 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
positive regulation of molecular function GO:0044093 136 0.016
purine nucleoside triphosphate catabolic process GO:0009146 108 0.016
regulation of anatomical structure size GO:0090066 163 0.016
regulation of neural precursor cell proliferation GO:2000177 35 0.015
cellular response to insulin stimulus GO:0032869 28 0.015
intracellular signal transduction GO:0035556 300 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
cellular response to hormone stimulus GO:0032870 44 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
pyridine nucleotide metabolic process GO:0019362 2 0.015
immune system process GO:0002376 347 0.015
Human
actin filament based process GO:0030029 220 0.014
digestive system development GO:0055123 149 0.014
positive regulation of growth GO:0045927 75 0.014
Worm
hexose metabolic process GO:0019318 8 0.014
regulation of cell shape GO:0008360 113 0.014
response to temperature stimulus GO:0009266 106 0.014
kidney development GO:0001822 3 0.014
cell proliferation GO:0008283 299 0.014
muscle cell development GO:0055001 50 0.013
wound healing GO:0042060 75 0.013
retina development in camera type eye GO:0060041 4 0.013
regulation of localization GO:0032879 275 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
tricarboxylic acid metabolic process GO:0072350 1 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
protein localization GO:0008104 284 0.013
response to other organism GO:0051707 293 0.013
nucleoside biosynthetic process GO:0009163 3 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
regulation of multicellular organism growth GO:0040014 40 0.013
Worm
regulation of cellular component size GO:0032535 98 0.013
wing disc morphogenesis GO:0007472 344 0.013
salivary gland development GO:0007431 162 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
sex differentiation GO:0007548 81 0.013
Worm
regulation of cellular catabolic process GO:0031329 157 0.013
ribonucleotide biosynthetic process GO:0009260 28 0.013
positive regulation of hydrolase activity GO:0051345 78 0.012
regulation of neurogenesis GO:0050767 158 0.012
response to biotic stimulus GO:0009607 294 0.012
exocrine system development GO:0035272 162 0.012
organic substance transport GO:0071702 257 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
Human
camera type eye development GO:0043010 4 0.012
negative regulation of nervous system development GO:0051961 92 0.012
regulation of nucleoside metabolic process GO:0009118 50 0.012
cellular homeostasis GO:0019725 80 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.011
establishment of localization in cell GO:0051649 402 0.011
regulation of protein modification process GO:0031399 112 0.011
positive regulation of cell death GO:0010942 69 0.011
carbohydrate biosynthetic process GO:0016051 17 0.011
lipid localization GO:0010876 54 0.011
Worm
digestive tract development GO:0048565 149 0.011
phagocytosis GO:0006909 215 0.011
negative regulation of neuroblast proliferation GO:0007406 27 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
response to carbohydrate GO:0009743 15 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
actin filament organization GO:0007015 126 0.011
purine ribonucleoside biosynthetic process GO:0046129 3 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
ion transport GO:0006811 145 0.011
cellular respiration GO:0045333 26 0.010
regulation of cellular protein metabolic process GO:0032268 243 0.010
Human
appendage morphogenesis GO:0035107 397 0.010
neural precursor cell proliferation GO:0061351 75 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
Worm
positive regulation of developmental growth GO:0048639 62 0.010
Worm
monocarboxylic acid transport GO:0015718 3 0.010
response to calcium ion GO:0051592 1 0.010
positive regulation of cellular biosynthetic process GO:0031328 316 0.010
regulation of developmental growth GO:0048638 174 0.010
Worm

Gapdh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.022
chromosomal disease DOID:0080014 0 0.017
gonadal dysgenesis DOID:14447 0 0.017