Drosophila melanogaster

43 known processes

CG10743 (Dmel_CG10743)

CG10743 gene product from transcript CG10743-RB

(Aliases: Dmel\CG10743,Liprin-beta)

CG10743 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
enzyme linked receptor protein signaling pathway GO:0007167 179 0.466
r7 cell differentiation GO:0045466 43 0.383
Fly
epithelial cell migration GO:0010631 148 0.338
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.316
immune response GO:0006955 246 0.312
response to biotic stimulus GO:0009607 294 0.308
stress activated mapk cascade GO:0051403 52 0.287
regulation of multicellular organismal development GO:2000026 414 0.282
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.238
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.236
response to bacterium GO:0009617 198 0.231
cellular protein modification process GO:0006464 438 0.226
regulation of cellular response to stress GO:0080135 89 0.218
taxis GO:0042330 304 0.209
Fly
response to external biotic stimulus GO:0043207 293 0.202
response to other organism GO:0051707 293 0.192
imaginal disc derived wing morphogenesis GO:0007476 337 0.189
eye development GO:0001654 323 0.188
Fly
regulation of immune system process GO:0002682 176 0.185
positive regulation of multicellular organismal process GO:0051240 143 0.181
regulation of growth GO:0040008 233 0.178
Fly
negative regulation of signaling GO:0023057 219 0.176
jnk cascade GO:0007254 50 0.172
immune response regulating signaling pathway GO:0002764 2 0.172
negative regulation of signal transduction GO:0009968 206 0.170
cell motility GO:0048870 251 0.163
stress activated protein kinase signaling cascade GO:0031098 55 0.156
negative regulation of response to stimulus GO:0048585 258 0.156
immune system process GO:0002376 347 0.151
compound eye photoreceptor cell differentiation GO:0001751 140 0.140
Fly
defense response to bacterium GO:0042742 178 0.135
regulation of developmental growth GO:0048638 174 0.135
Fly
response to lipopolysaccharide GO:0032496 4 0.133
sensory organ morphogenesis GO:0090596 260 0.128
Fly
epithelium migration GO:0090132 148 0.128
response to organic substance GO:0010033 284 0.124
cell migration GO:0016477 238 0.124
positive regulation of cell communication GO:0010647 250 0.123
wing disc morphogenesis GO:0007472 344 0.118
regulation of cell differentiation GO:0045595 302 0.116
Fly
growth GO:0040007 359 0.115
negative regulation of multicellular organismal process GO:0051241 142 0.115
Fly
stem cell development GO:0048864 79 0.111
phosphorylation GO:0016310 294 0.110
positive regulation of immune response GO:0050778 63 0.108
imaginal disc derived appendage morphogenesis GO:0035114 395 0.106
imaginal disc pattern formation GO:0007447 91 0.101
response to oxygen containing compound GO:1901700 200 0.098
positive regulation of cell development GO:0010720 61 0.096
regulation of nervous system development GO:0051960 248 0.094
Fly
regulation of mapk cascade GO:0043408 92 0.090
regulation of cellular protein metabolic process GO:0032268 243 0.090
cellular response to chemical stimulus GO:0070887 199 0.088
regulation of immune response GO:0050776 118 0.088
appendage development GO:0048736 401 0.087
cellular response to organic substance GO:0071310 132 0.087
tissue migration GO:0090130 155 0.087
positive regulation of nervous system development GO:0051962 69 0.085
positive regulation of signal transduction GO:0009967 223 0.085
defense response GO:0006952 300 0.083
intracellular signal transduction GO:0035556 300 0.082
apoptotic cell clearance GO:0043277 14 0.081
synapse organization GO:0050808 196 0.081
developmental programmed cell death GO:0010623 138 0.081
aromatic compound catabolic process GO:0019439 166 0.080
positive regulation of response to stimulus GO:0048584 323 0.079
dorsal ventral axis specification GO:0009950 66 0.077
central nervous system development GO:0007417 201 0.075
imaginal disc derived appendage development GO:0048737 399 0.075
regulation of jnk cascade GO:0046328 40 0.074
eye morphogenesis GO:0048592 260 0.073
Fly
histone modification GO:0016570 106 0.072
protein localization GO:0008104 284 0.071
positive regulation of protein metabolic process GO:0051247 128 0.070
regulation of synapse assembly GO:0051963 94 0.070
Fly
axon guidance GO:0007411 233 0.069
Fly
regulation of neurogenesis GO:0050767 158 0.069
Fly
regulation of r7 cell differentiation GO:0045676 15 0.069
ameboidal type cell migration GO:0001667 151 0.069
dephosphorylation GO:0016311 51 0.068
tube development GO:0035295 244 0.067
regulation of localization GO:0032879 275 0.066
Fly
stem cell differentiation GO:0048863 117 0.065
compound eye development GO:0048749 307 0.065
Fly
cellular response to dna damage stimulus GO:0006974 223 0.063
immune response activating signal transduction GO:0002757 2 0.063
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.062
positive regulation of cell differentiation GO:0045597 64 0.061
defense response to gram negative bacterium GO:0050829 94 0.061
detection of light stimulus GO:0009583 58 0.061
positive regulation of signaling GO:0023056 243 0.060
cell death GO:0008219 279 0.059
cellular macromolecule localization GO:0070727 220 0.058
compound eye morphogenesis GO:0001745 249 0.058
Fly
response to abiotic stimulus GO:0009628 341 0.057
axonogenesis GO:0007409 290 0.057
apoptotic process GO:0006915 159 0.054
regionalization GO:0003002 416 0.054
regulation of response to external stimulus GO:0032101 115 0.054
Fly
protein phosphorylation GO:0006468 169 0.053
positive regulation of cellular protein metabolic process GO:0032270 118 0.052
chemotaxis GO:0006935 249 0.052
Fly
negative regulation of cell cycle process GO:0010948 109 0.051
defense response to other organism GO:0098542 225 0.050
developmental pigmentation GO:0048066 68 0.050
response to growth factor GO:0070848 31 0.050
autophagy GO:0006914 108 0.048
cellular catabolic process GO:0044248 372 0.047
negative regulation of cell development GO:0010721 62 0.046
catabolic process GO:0009056 409 0.045
endocytosis GO:0006897 310 0.045
hindgut morphogenesis GO:0007442 58 0.044
multicellular organism growth GO:0035264 46 0.044
cellular response to growth factor stimulus GO:0071363 30 0.043
negative regulation of mapk cascade GO:0043409 23 0.043
cellular protein localization GO:0034613 160 0.043
border follicle cell migration GO:0007298 113 0.043
eye photoreceptor cell fate commitment GO:0042706 37 0.042
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.042
photoreceptor cell differentiation GO:0046530 170 0.042
Fly
neurological system process GO:0050877 358 0.041
actin filament organization GO:0007015 126 0.040
nucleocytoplasmic transport GO:0006913 72 0.040
connective tissue development GO:0061448 3 0.040
mapk cascade GO:0000165 107 0.040
intracellular transport GO:0046907 228 0.039
dorsal ventral pattern formation GO:0009953 133 0.039
regulation of cellular catabolic process GO:0031329 157 0.038
embryonic development via the syncytial blastoderm GO:0001700 148 0.038
cellular ketone metabolic process GO:0042180 24 0.038
localization of cell GO:0051674 257 0.037
establishment of localization in cell GO:0051649 402 0.037
Fly
single organism intracellular transport GO:1902582 207 0.036
regulation of neuron differentiation GO:0045664 103 0.036
Fly
cellular response to radiation GO:0071478 52 0.036
cellular response to molecule of bacterial origin GO:0071219 3 0.036
regulation of cellular response to growth factor stimulus GO:0090287 13 0.036
organophosphate metabolic process GO:0019637 195 0.035
neuron fate commitment GO:0048663 50 0.035
positive regulation of neurogenesis GO:0050769 41 0.035
protein complex assembly GO:0006461 200 0.035
signal transduction by phosphorylation GO:0023014 107 0.034
regulation of stress activated mapk cascade GO:0032872 41 0.034
posttranscriptional regulation of gene expression GO:0010608 145 0.034
negative regulation of stress activated protein kinase signaling cascade GO:0070303 20 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.033
long term memory GO:0007616 62 0.033
regulation of imaginal disc growth GO:0045570 26 0.033
regulation of photoreceptor cell differentiation GO:0046532 34 0.033
appendage morphogenesis GO:0035107 397 0.032
regulation of response to stress GO:0080134 200 0.032
nuclear transport GO:0051169 72 0.032
positive regulation of immune system process GO:0002684 68 0.032
axon target recognition GO:0007412 16 0.032
regulation of phosphorus metabolic process GO:0051174 210 0.031
small molecule metabolic process GO:0044281 305 0.031
axis specification GO:0009798 167 0.031
immune effector process GO:0002252 98 0.031
positive regulation of molecular function GO:0044093 136 0.031
body morphogenesis GO:0010171 2 0.031
organic acid metabolic process GO:0006082 103 0.031
macromolecular complex assembly GO:0065003 256 0.030
developmental growth GO:0048589 280 0.030
phagocytosis recognition GO:0006910 1 0.030
detection of stimulus GO:0051606 156 0.030
regulation of cell death GO:0010941 173 0.030
positive regulation of cellular component biogenesis GO:0044089 80 0.030
regulation of cell size GO:0008361 63 0.029
Fly
embryonic organ development GO:0048568 50 0.029
digestive tract morphogenesis GO:0048546 127 0.029
positive regulation of developmental process GO:0051094 143 0.029
positive regulation of cellular component organization GO:0051130 156 0.028
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.028
negative regulation of phosphorylation GO:0042326 35 0.028
regulation of multi organism process GO:0043900 131 0.028
phagocytosis GO:0006909 215 0.028
actin filament based process GO:0030029 220 0.028
compound eye photoreceptor fate commitment GO:0001752 36 0.028
chromosome organization GO:0051276 360 0.027
eye pigmentation GO:0048069 43 0.027
biological adhesion GO:0022610 138 0.027
negative regulation of cell differentiation GO:0045596 143 0.027
cellular macromolecule catabolic process GO:0044265 136 0.027
ras protein signal transduction GO:0007265 88 0.026
r7 cell fate commitment GO:0007465 12 0.026
innate immune response GO:0045087 144 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
wound healing GO:0042060 75 0.026
multi organism behavior GO:0051705 175 0.026
positive regulation of catalytic activity GO:0043085 118 0.026
single organism cellular localization GO:1902580 180 0.025
positive regulation of transport GO:0051050 92 0.025
response to wounding GO:0009611 94 0.025
organonitrogen compound biosynthetic process GO:1901566 117 0.025
organic substance catabolic process GO:1901575 308 0.024
negative regulation of cell communication GO:0010648 223 0.024
small gtpase mediated signal transduction GO:0007264 88 0.024
regulation of protein metabolic process GO:0051246 256 0.024
ovarian follicle cell development GO:0030707 248 0.024
digestive system development GO:0055123 149 0.024
oxidoreduction coenzyme metabolic process GO:0006733 2 0.023
transmembrane transport GO:0055085 139 0.023
positive regulation of mapk cascade GO:0043410 63 0.023
exocrine system development GO:0035272 162 0.023
regulation of cytoplasmic transport GO:1903649 47 0.023
eye photoreceptor cell differentiation GO:0001754 145 0.023
Fly
cellular amine metabolic process GO:0044106 12 0.022
actin cytoskeleton organization GO:0030036 206 0.022
regulation of epithelial cell proliferation GO:0050678 4 0.022
positive regulation of intracellular signal transduction GO:1902533 116 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
embryonic morphogenesis GO:0048598 206 0.022
negative regulation of kinase activity GO:0033673 16 0.022
positive regulation of proteolysis GO:0045862 52 0.021
cellular response to lipopolysaccharide GO:0071222 3 0.021
death GO:0016265 284 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
regulation of protein localization GO:0032880 76 0.021
negative regulation of developmental process GO:0051093 201 0.021
Fly
cell cycle checkpoint GO:0000075 95 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
organonitrogen compound metabolic process GO:1901564 318 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.020
embryonic hindgut morphogenesis GO:0048619 48 0.020
regulation of cell development GO:0060284 215 0.020
Fly
positive regulation of synapse assembly GO:0051965 29 0.020
tetraterpenoid metabolic process GO:0016108 1 0.020
response to paraquat GO:1901562 4 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
vesicle mediated transport GO:0016192 381 0.019
Fly
inositol lipid mediated signaling GO:0048017 4 0.019
chromatin organization GO:0006325 207 0.019
negative regulation of immune system process GO:0002683 50 0.019
maintenance of location GO:0051235 73 0.019
regulation of locomotion GO:0040012 42 0.019
Fly
negative regulation of nervous system development GO:0051961 92 0.018
Fly
carboxylic acid metabolic process GO:0019752 92 0.018
regulation of molecular function GO:0065009 217 0.018
regulation of transport GO:0051049 181 0.018
protein modification process GO:0036211 438 0.018
negative regulation of neurogenesis GO:0050768 53 0.018
response to uv GO:0009411 24 0.018
multicellular organismal aging GO:0010259 140 0.018
chaeta morphogenesis GO:0008407 42 0.018
programmed cell death GO:0012501 257 0.018
lipid metabolic process GO:0006629 121 0.018
guanosine containing compound metabolic process GO:1901068 74 0.018
germ line stem cell maintenance GO:0030718 50 0.018
protein import into nucleus GO:0006606 51 0.018
decapentaplegic signaling pathway GO:0008101 19 0.018
salivary gland development GO:0007431 162 0.018
regulation of cellular localization GO:0060341 136 0.017
regulation of intracellular transport GO:0032386 64 0.017
membrane organization GO:0061024 112 0.017
protein targeting to nucleus GO:0044744 51 0.017
protein dephosphorylation GO:0006470 27 0.017
negative regulation of response to external stimulus GO:0032102 22 0.017
positive regulation of jun kinase activity GO:0043507 4 0.017
regulation of cell proliferation GO:0042127 163 0.017
protein complex biogenesis GO:0070271 201 0.017
segmentation GO:0035282 207 0.017
regulation of notch signaling pathway GO:0008593 100 0.017
regulation of vesicle mediated transport GO:0060627 59 0.017
regulation of catalytic activity GO:0050790 185 0.017
nuclear import GO:0051170 51 0.017
regulation of apoptotic process GO:0042981 130 0.017
oxoacid metabolic process GO:0043436 103 0.017
organelle localization GO:0051640 148 0.016
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
negative regulation of molecular function GO:0044092 51 0.016
mitotic spindle organization GO:0007052 220 0.016
signal transduction in response to dna damage GO:0042770 3 0.016
regulation of establishment of protein localization GO:0070201 61 0.016
spindle organization GO:0007051 253 0.016
positive regulation of neuron differentiation GO:0045666 26 0.016
negative regulation of cell cycle GO:0045786 116 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
establishment of protein localization GO:0045184 163 0.016
negative regulation of erbb signaling pathway GO:1901185 29 0.016
response to lipid GO:0033993 38 0.016
reproductive behavior GO:0019098 122 0.016
positive regulation of gene expression GO:0010628 290 0.016
nuclear division GO:0000280 332 0.015
cilium assembly GO:0042384 38 0.015
muscle structure development GO:0061061 224 0.015
negative regulation of transferase activity GO:0051348 18 0.015
synaptic vesicle localization GO:0097479 53 0.015
Fly
cellular response to abiotic stimulus GO:0071214 58 0.015
stem cell maintenance GO:0019827 67 0.015
regulation of protein serine threonine kinase activity GO:0071900 25 0.015
regulation of endocytosis GO:0030100 37 0.015
response to radiation GO:0009314 155 0.015
apoptotic signaling pathway GO:0097190 27 0.015
response to glucose GO:0009749 2 0.015
positive regulation of lipid metabolic process GO:0045834 4 0.015
developmental cell growth GO:0048588 52 0.015
Fly
extrinsic apoptotic signaling pathway GO:0097191 1 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
regulation of cellular component movement GO:0051270 42 0.014
Fly
regulation of map kinase activity GO:0043405 17 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
gliogenesis GO:0042063 80 0.014
regulation of cytoskeleton organization GO:0051493 89 0.014
regulation of ion transport GO:0043269 39 0.014
regulation of protein modification process GO:0031399 112 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
regulation of synapse structure and activity GO:0050803 128 0.014
Fly
digestive tract development GO:0048565 149 0.014
regulation of innate immune response GO:0045088 71 0.013
mesenchymal cell development GO:0014031 1 0.013
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.013
peptidyl amino acid modification GO:0018193 105 0.013
erbb signaling pathway GO:0038127 58 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
Fly
mesenchymal cell differentiation GO:0048762 1 0.013
notch signaling pathway GO:0007219 120 0.013
negative regulation of cell cycle phase transition GO:1901988 103 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
synaptic transmission GO:0007268 288 0.013
Fly
forebrain development GO:0030900 2 0.013
endomembrane system organization GO:0010256 119 0.013
organ growth GO:0035265 56 0.013
regulation of defense response GO:0031347 102 0.013
response to alcohol GO:0097305 95 0.013
muscle system process GO:0003012 21 0.013
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.012
negative regulation of cell death GO:0060548 81 0.012
chromatin modification GO:0016568 147 0.012
response to organonitrogen compound GO:0010243 75 0.012
protein acylation GO:0043543 42 0.012
protein localization to nucleus GO:0034504 55 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
single organism membrane organization GO:0044802 93 0.012
cell proliferation GO:0008283 299 0.012
activation of immune response GO:0002253 5 0.012
establishment of protein localization to organelle GO:0072594 62 0.012
heterocycle catabolic process GO:0046700 166 0.012
embryonic pattern specification GO:0009880 174 0.012
negative regulation of protein phosphorylation GO:0001933 17 0.012
regulation of cell shape GO:0008360 113 0.011
developmental growth involved in morphogenesis GO:0060560 65 0.011
Fly
tube morphogenesis GO:0035239 191 0.011
negative regulation of ras protein signal transduction GO:0046580 13 0.011
regulation of intracellular protein transport GO:0033157 46 0.011
determination of adult lifespan GO:0008340 137 0.011
wing disc pattern formation GO:0035222 66 0.011
nuclear export GO:0051168 24 0.011
epithelial cell development GO:0002064 274 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
covalent chromatin modification GO:0016569 106 0.011
regulation of erbb signaling pathway GO:1901184 42 0.011
hemocyte differentiation GO:0042386 38 0.011
rrna processing GO:0006364 3 0.011
regulation of phosphorylation GO:0042325 147 0.011
negative regulation of phosphorus metabolic process GO:0010563 45 0.011
regulation of catabolic process GO:0009894 170 0.011
macromolecule catabolic process GO:0009057 161 0.011
regulation of organ growth GO:0046620 42 0.011
positive regulation of cell migration GO:0030335 2 0.011
tissue death GO:0016271 102 0.011
positive regulation of protein modification process GO:0031401 58 0.011
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
positive regulation of cell motility GO:2000147 3 0.011
compound eye photoreceptor development GO:0042051 78 0.011
Fly
mrna 3 end processing GO:0031124 28 0.011
cellular response to biotic stimulus GO:0071216 4 0.010
striated muscle adaptation GO:0014888 1 0.010
regulation of stress fiber assembly GO:0051492 6 0.010
regulation of cellular component size GO:0032535 98 0.010
Fly
cell division GO:0051301 248 0.010
regulation of phosphatase activity GO:0010921 3 0.010
epidermal growth factor receptor signaling pathway GO:0007173 58 0.010
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.010

CG10743 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012