Drosophila melanogaster

46 known processes

scu (Dmel_CG7113)

scully

(Aliases: 17beta-HSD10,l(1)16Fd,l(1)17Ad,HL-X,HLII,Scu,Dmel\CG7113,CG7113)

scu biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
monocarboxylic acid metabolic process GO:0032787 29 0.377
establishment of localization in cell GO:0051649 402 0.312
intracellular transport GO:0046907 228 0.306
single organism cellular localization GO:1902580 180 0.259
eye morphogenesis GO:0048592 260 0.246
male gamete generation GO:0048232 201 0.242
membrane biogenesis GO:0044091 8 0.241
single organism intracellular transport GO:1902582 207 0.230
oxoacid metabolic process GO:0043436 103 0.215
compound eye development GO:0048749 307 0.210
single organism membrane organization GO:0044802 93 0.210
compound eye photoreceptor development GO:0042051 78 0.206
single organism catabolic process GO:0044712 228 0.197
protein transport GO:0015031 155 0.194
sensory organ morphogenesis GO:0090596 260 0.191
immune system process GO:0002376 347 0.179
organic substance transport GO:0071702 257 0.166
cellular catabolic process GO:0044248 372 0.163
transmembrane transport GO:0055085 139 0.161
regulation of localization GO:0032879 275 0.159
small molecule metabolic process GO:0044281 305 0.159
eye development GO:0001654 323 0.155
photoreceptor cell differentiation GO:0046530 170 0.151
cellular macromolecule localization GO:0070727 220 0.147
rhabdomere development GO:0042052 38 0.142
response to abiotic stimulus GO:0009628 341 0.139
catabolic process GO:0009056 409 0.135
regulation of transport GO:0051049 181 0.130
negative regulation of gene expression GO:0010629 387 0.128
membrane organization GO:0061024 112 0.121
ion transport GO:0006811 145 0.114
photoreceptor cell development GO:0042461 96 0.110
actin cytoskeleton organization GO:0030036 206 0.103
intracellular protein transmembrane transport GO:0065002 4 0.100
positive regulation of biosynthetic process GO:0009891 316 0.093
endomembrane system organization GO:0010256 119 0.093
spindle organization GO:0007051 253 0.088
single organism biosynthetic process GO:0044711 206 0.088
intracellular protein transport GO:0006886 104 0.087
aggressive behavior GO:0002118 63 0.086
spermatogenesis GO:0007283 200 0.078
protein localization GO:0008104 284 0.077
multi organism behavior GO:0051705 175 0.077
establishment of protein localization GO:0045184 163 0.076
eye photoreceptor cell differentiation GO:0001754 145 0.071
homeostatic process GO:0042592 199 0.070
cytoplasmic transport GO:0016482 130 0.069
intracellular protein transmembrane import GO:0044743 4 0.067
lipid catabolic process GO:0016042 21 0.067
establishment of tissue polarity GO:0007164 87 0.066
organic substance catabolic process GO:1901575 308 0.066
chromosome organization GO:0051276 360 0.066
organic acid metabolic process GO:0006082 103 0.065
eye photoreceptor cell development GO:0042462 81 0.065
regulation of anatomical structure size GO:0090066 163 0.064
cell death GO:0008219 279 0.064
inter male aggressive behavior GO:0002121 60 0.061
cellular response to chemical stimulus GO:0070887 199 0.059
regulation of cellular localization GO:0060341 136 0.058
spermatid differentiation GO:0048515 114 0.055
compound eye photoreceptor cell differentiation GO:0001751 140 0.052
posttranscriptional regulation of gene expression GO:0010608 145 0.050
regulation of protein metabolic process GO:0051246 256 0.050
response to organic substance GO:0010033 284 0.050
positive regulation of cellular biosynthetic process GO:0031328 316 0.049
protein transmembrane transport GO:0071806 4 0.048
cellular protein localization GO:0034613 160 0.047
regulation of anatomical structure morphogenesis GO:0022603 242 0.047
transcription from rna polymerase ii promoter GO:0006366 368 0.047
cell migration GO:0016477 238 0.045
actomyosin structure organization GO:0031032 56 0.044
response to decreased oxygen levels GO:0036293 58 0.044
fatty acid metabolic process GO:0006631 20 0.043
mitotic nuclear division GO:0007067 213 0.042
meiotic cell cycle process GO:1903046 132 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.042
anatomical structure homeostasis GO:0060249 97 0.041
response to nutrient levels GO:0031667 114 0.039
regulation of cell differentiation GO:0045595 302 0.039
regulation of intracellular transport GO:0032386 64 0.039
carboxylic acid metabolic process GO:0019752 92 0.039
cellular amino acid metabolic process GO:0006520 61 0.038
positive regulation of signal transduction GO:0009967 223 0.038
death GO:0016265 284 0.038
response to bacterium GO:0009617 198 0.037
circadian behavior GO:0048512 76 0.037
organelle assembly GO:0070925 198 0.037
single organism behavior GO:0044708 391 0.036
inorganic cation transmembrane transport GO:0098662 61 0.036
negative regulation of cellular biosynthetic process GO:0031327 277 0.036
nuclear division GO:0000280 332 0.036
positive regulation of cell communication GO:0010647 250 0.035
response to mercury ion GO:0046689 3 0.035
organonitrogen compound metabolic process GO:1901564 318 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.035
anion transport GO:0006820 41 0.035
cellular protein modification process GO:0006464 438 0.033
response to cold GO:0009409 13 0.033
cation transmembrane transport GO:0098655 88 0.033
muscle cell differentiation GO:0042692 103 0.033
compound eye morphogenesis GO:0001745 249 0.033
regulation of organelle organization GO:0033043 196 0.033
autophagy GO:0006914 108 0.032
multi multicellular organism process GO:0044706 123 0.032
post embryonic appendage morphogenesis GO:0035120 385 0.032
kidney development GO:0001822 3 0.031
regulation of cell cycle GO:0051726 291 0.031
hippo signaling GO:0035329 20 0.031
neurological system process GO:0050877 358 0.031
reproductive behavior GO:0019098 122 0.031
detection of light stimulus GO:0009583 58 0.030
response to extracellular stimulus GO:0009991 116 0.030
proteolysis GO:0006508 192 0.029
ion transmembrane transport GO:0034220 122 0.029
negative regulation of transcription dna templated GO:0045892 237 0.028
intracellular signal transduction GO:0035556 300 0.028
imaginal disc derived wing morphogenesis GO:0007476 337 0.028
developmental growth GO:0048589 280 0.028
positive regulation of macromolecule metabolic process GO:0010604 405 0.027
cellular modified amino acid metabolic process GO:0006575 45 0.027
hormone metabolic process GO:0042445 33 0.027
golgi organization GO:0007030 66 0.026
positive regulation of response to stimulus GO:0048584 323 0.026
regulation of embryonic development GO:0045995 68 0.026
spermatocyte division GO:0048137 13 0.026
extracellular structure organization GO:0043062 46 0.026
cellular ketone metabolic process GO:0042180 24 0.026
monocarboxylic acid catabolic process GO:0072329 10 0.025
regulation of cellular component biogenesis GO:0044087 201 0.025
positive regulation of rna biosynthetic process GO:1902680 266 0.025
regulation of catabolic process GO:0009894 170 0.025
regulation of cellular component size GO:0032535 98 0.025
wound healing GO:0042060 75 0.024
establishment or maintenance of cell polarity GO:0007163 167 0.024
negative regulation of cellular metabolic process GO:0031324 382 0.024
response to organic cyclic compound GO:0014070 89 0.024
developmental pigmentation GO:0048066 68 0.023
plasma membrane organization GO:0007009 26 0.023
positive regulation of catalytic activity GO:0043085 118 0.023
body morphogenesis GO:0010171 2 0.023
negative regulation of cell cycle GO:0045786 116 0.023
negative regulation of signaling GO:0023057 219 0.023
organelle fission GO:0048285 340 0.022
response to oxidative stress GO:0006979 86 0.022
regulation of cell cycle process GO:0010564 181 0.022
positive regulation of multicellular organismal process GO:0051240 143 0.022
protein targeting GO:0006605 64 0.022
response to biotic stimulus GO:0009607 294 0.022
regulation of protein transport GO:0051223 57 0.022
regulation of catalytic activity GO:0050790 185 0.022
cation transport GO:0006812 110 0.022
spindle assembly GO:0051225 80 0.022
cellular component assembly involved in morphogenesis GO:0010927 151 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
regulation of protein localization GO:0032880 76 0.021
peptide metabolic process GO:0006518 80 0.021
cell motility GO:0048870 251 0.021
nucleoside catabolic process GO:0009164 112 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
localization of cell GO:0051674 257 0.020
response to other organism GO:0051707 293 0.020
regulation of molecular function GO:0065009 217 0.020
cellular homeostasis GO:0019725 80 0.020
response to inorganic substance GO:0010035 44 0.020
modification dependent macromolecule catabolic process GO:0043632 79 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.020
protein complex assembly GO:0006461 200 0.020
Rat
cellular response to dna damage stimulus GO:0006974 223 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.019
morphogenesis of a polarized epithelium GO:0001738 93 0.019
imaginal disc derived appendage morphogenesis GO:0035114 395 0.019
cytoplasm organization GO:0007028 64 0.019
golgi to plasma membrane protein transport GO:0043001 8 0.019
reactive oxygen species metabolic process GO:0072593 22 0.019
developmental maturation GO:0021700 172 0.019
regulation of nervous system development GO:0051960 248 0.019
wing disc morphogenesis GO:0007472 344 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
endocytosis GO:0006897 310 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.018
nucleotide metabolic process GO:0009117 161 0.018
gene silencing GO:0016458 138 0.018
establishment of protein localization to organelle GO:0072594 62 0.018
establishment of protein localization to plasma membrane GO:0090002 9 0.018
small molecule catabolic process GO:0044282 21 0.018
cellular amide metabolic process GO:0043603 80 0.018
mitotic spindle organization GO:0007052 220 0.018
imaginal disc derived appendage development GO:0048737 399 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.018
inorganic ion transmembrane transport GO:0098660 73 0.018
respiratory system development GO:0060541 213 0.018
cuticle development GO:0042335 86 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
cellular protein catabolic process GO:0044257 83 0.017
biological adhesion GO:0022610 138 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.017
spindle assembly involved in mitosis GO:0090307 50 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
cellular lipid metabolic process GO:0044255 83 0.016
regulation of establishment of protein localization GO:0070201 61 0.016
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.016
defense response to other organism GO:0098542 225 0.016
appendage morphogenesis GO:0035107 397 0.016
notch signaling pathway GO:0007219 120 0.016
appendage development GO:0048736 401 0.016
response to oxygen containing compound GO:1901700 200 0.016
cellular response to extracellular stimulus GO:0031668 64 0.016
growth GO:0040007 359 0.016
cellular response to nutrient levels GO:0031669 62 0.016
cellular response to oxygen containing compound GO:1901701 79 0.015
cellular response to decreased oxygen levels GO:0036294 30 0.015
programmed cell death GO:0012501 257 0.015
positive regulation of protein metabolic process GO:0051247 128 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
cortical actin cytoskeleton organization GO:0030866 24 0.015
cell cycle phase transition GO:0044770 140 0.015
lipid metabolic process GO:0006629 121 0.015
regulation of translation GO:0006417 56 0.015
cell division GO:0051301 248 0.015
negative regulation of developmental process GO:0051093 201 0.015
regulation of organ morphogenesis GO:2000027 78 0.015
phosphatidic acid metabolic process GO:0046473 1 0.015
small molecule biosynthetic process GO:0044283 37 0.015
organophosphate catabolic process GO:0046434 112 0.015
response to temperature stimulus GO:0009266 106 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
embryo development ending in birth or egg hatching GO:0009792 152 0.015
striated muscle myosin thick filament assembly GO:0071688 3 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
gonad development GO:0008406 50 0.014
Rat Worm
rna splicing GO:0008380 83 0.014
muscle structure development GO:0061061 224 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
regulation of notch signaling pathway GO:0008593 100 0.014
peroxisome organization GO:0007031 14 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
defense response to bacterium GO:0042742 178 0.014
regulation of protein localization to plasma membrane GO:1903076 7 0.014
chitin based cuticle development GO:0040003 49 0.014
pole plasm rna localization GO:0007316 52 0.014
regulation of golgi to plasma membrane protein transport GO:0042996 6 0.014
regulation of cell shape GO:0008360 113 0.014
dna metabolic process GO:0006259 227 0.014
regulation of transmembrane transport GO:0034762 27 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.013
immune response GO:0006955 246 0.013
establishment of protein localization to membrane GO:0090150 11 0.013
positive regulation of signaling GO:0023056 243 0.013
response to endogenous stimulus GO:0009719 119 0.013
cellular response to external stimulus GO:0071496 66 0.013
carbohydrate biosynthetic process GO:0016051 17 0.013
establishment of protein localization to peroxisome GO:0072663 2 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
positive regulation of gene expression GO:0010628 290 0.013
nucleoside metabolic process GO:0009116 127 0.013
response to wounding GO:0009611 94 0.013
protein targeting to peroxisome GO:0006625 2 0.013
vesicle mediated transport GO:0016192 381 0.013
cuticle pattern formation GO:0035017 27 0.013
cellular lipid catabolic process GO:0044242 16 0.013
histolysis GO:0007559 102 0.013
chemical homeostasis GO:0048878 92 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
positive regulation of transport GO:0051050 92 0.013
intrinsic apoptotic signaling pathway GO:0097193 16 0.013
positive regulation of molecular function GO:0044093 136 0.013
cellular response to organic cyclic compound GO:0071407 32 0.013
regionalization GO:0003002 416 0.012
dendrite development GO:0016358 204 0.012
endosomal transport GO:0016197 44 0.012
microtubule organizing center organization GO:0031023 168 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
oocyte anterior posterior axis specification GO:0007314 72 0.012
alditol phosphate metabolic process GO:0052646 2 0.012
response to light stimulus GO:0009416 124 0.012
eye pigment metabolic process GO:0042441 33 0.012
positive regulation of protein kinase activity GO:0045860 25 0.012
protein localization to organelle GO:0033365 82 0.012
regulation of rna splicing GO:0043484 69 0.012
organic hydroxy compound biosynthetic process GO:1901617 21 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
exocrine system development GO:0035272 162 0.012
cellular response to organic substance GO:0071310 132 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
positive regulation of cell differentiation GO:0045597 64 0.012
response to hypoxia GO:0001666 53 0.012
regulation of mrna splicing via spliceosome GO:0048024 64 0.012
spermatid development GO:0007286 98 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
protein localization to plasma membrane GO:0072659 13 0.012
learning or memory GO:0007611 141 0.012
lateral inhibition GO:0046331 206 0.011
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.011
centrosome cycle GO:0007098 137 0.011
purine containing compound catabolic process GO:0072523 112 0.011
protein complex biogenesis GO:0070271 201 0.011
Rat
vitamin metabolic process GO:0006766 2 0.011
negative regulation of signal transduction GO:0009968 206 0.011
multicellular organismal homeostasis GO:0048871 41 0.011
regulation of response to oxidative stress GO:1902882 4 0.011
regulation of mitochondrion organization GO:0010821 12 0.011
epithelial cell development GO:0002064 274 0.011
response to oxygen levels GO:0070482 59 0.011
protein localization to membrane GO:0072657 19 0.011
cellular response to starvation GO:0009267 61 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
macromolecule catabolic process GO:0009057 161 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
negative regulation of cell death GO:0060548 81 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
sensory perception of pain GO:0019233 4 0.011
glycosyl compound catabolic process GO:1901658 112 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.010
sister chromatid segregation GO:0000819 92 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
steroid biosynthetic process GO:0006694 16 0.010
actin polymerization or depolymerization GO:0008154 31 0.010
negative regulation of organ growth GO:0046621 15 0.010
positive regulation of developmental process GO:0051094 143 0.010
cell aging GO:0007569 2 0.010
Rat
negative regulation of nucleic acid templated transcription GO:1903507 240 0.010
embryonic morphogenesis GO:0048598 206 0.010
xenobiotic catabolic process GO:0042178 1 0.010
fatty acid catabolic process GO:0009062 9 0.010
digestive system development GO:0055123 149 0.010
developmental programmed cell death GO:0010623 138 0.010
epithelial cell differentiation GO:0030855 322 0.010
centrosome organization GO:0051297 163 0.010

scu disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
disease of metabolism DOID:0014667 0 0.016
nervous system disease DOID:863 0 0.016
cardiovascular system disease DOID:1287 0 0.015