Drosophila melanogaster

14 known processes

Hsp60 (Dmel_CG12101)

Heat shock protein 60

(Aliases: l(1)HM21,l(1)BP5,12,l(1)L12,d-hsp60,cpn60,l(1)G8,hsp60,l(1)dp025,Mmp-P1,Dmel\CG12101,BP5,CG12101,G62,HSP60,Dmhsp60,Hsp60A,Cpn60,l(1)10Ac)

Hsp60 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytoplasmic microtubule organization GO:0031122 22 0.208
spindle assembly involved in mitosis GO:0090307 50 0.200
larval development GO:0002164 104 0.196
Worm
body morphogenesis GO:0010171 2 0.170
mitotic spindle organization GO:0007052 220 0.140
reproductive structure development GO:0048608 74 0.139
carboxylic acid metabolic process GO:0019752 92 0.133
multicellular organism growth GO:0035264 46 0.126
positive regulation of developmental process GO:0051094 143 0.122
cell motility GO:0048870 251 0.120
regulation of developmental growth GO:0048638 174 0.115
response to abiotic stimulus GO:0009628 341 0.112
localization of cell GO:0051674 257 0.104
sex differentiation GO:0007548 81 0.095
mitochondrion organization GO:0007005 65 0.093
nuclear division GO:0000280 332 0.092
embryo development ending in birth or egg hatching GO:0009792 152 0.084
Worm
small molecule metabolic process GO:0044281 305 0.078
alpha amino acid metabolic process GO:1901605 20 0.078
cellular amino acid metabolic process GO:0006520 61 0.077
positive regulation of nucleic acid templated transcription GO:1903508 266 0.076
development of primary sexual characteristics GO:0045137 50 0.073
positive regulation of programmed cell death GO:0043068 62 0.072
Human
cell recognition GO:0008037 102 0.072
organonitrogen compound metabolic process GO:1901564 318 0.069
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.065
apoptotic process GO:0006915 159 0.061
Human
organonitrogen compound biosynthetic process GO:1901566 117 0.061
growth GO:0040007 359 0.058
Zebrafish
cell migration GO:0016477 238 0.058
cell death GO:0008219 279 0.056
Human
neurological system process GO:0050877 358 0.052
regulation of growth GO:0040008 233 0.052
positive regulation of cell death GO:0010942 69 0.050
Human
reproductive system development GO:0061458 74 0.050
gonad development GO:0008406 50 0.048
positive regulation of cellular biosynthetic process GO:0031328 316 0.047
spindle organization GO:0007051 253 0.046
organelle fission GO:0048285 340 0.041
organic acid metabolic process GO:0006082 103 0.041
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.040
nucleobase containing small molecule metabolic process GO:0055086 174 0.040
purine containing compound metabolic process GO:0072521 155 0.039
negative regulation of nucleic acid templated transcription GO:1903507 240 0.038
endocytosis GO:0006897 310 0.037
cell proliferation GO:0008283 299 0.036
Human
immune response regulating signaling pathway GO:0002764 2 0.035
Human
neuron recognition GO:0008038 101 0.035
positive regulation of developmental growth GO:0048639 62 0.035
regulation of multicellular organism growth GO:0040014 40 0.034
brain development GO:0007420 120 0.033
response to decreased oxygen levels GO:0036293 58 0.033
organelle assembly GO:0070925 198 0.033
ribose phosphate metabolic process GO:0019693 145 0.032
protein modification process GO:0036211 438 0.032
vesicle mediated transport GO:0016192 381 0.032
regulation of intracellular signal transduction GO:1902531 236 0.031
regulation of cell cycle process GO:0010564 181 0.031
response to oxygen levels GO:0070482 59 0.031
purine nucleoside metabolic process GO:0042278 127 0.031
ribonucleoside metabolic process GO:0009119 127 0.031
purine ribonucleotide metabolic process GO:0009150 145 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.031
organonitrogen compound catabolic process GO:1901565 128 0.030
nucleoside triphosphate metabolic process GO:0009141 120 0.029
developmental growth GO:0048589 280 0.029
Zebrafish
ribonucleoside triphosphate metabolic process GO:0009199 119 0.028
central nervous system development GO:0007417 201 0.028
mitotic nuclear division GO:0007067 213 0.028
purine containing compound biosynthetic process GO:0072522 30 0.027
protein complex biogenesis GO:0070271 201 0.027
nucleoside phosphate metabolic process GO:0006753 162 0.027
regulation of phosphorylation GO:0042325 147 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.024
positive regulation of molecular function GO:0044093 136 0.024
Human
response to radiation GO:0009314 155 0.024
ribonucleotide biosynthetic process GO:0009260 28 0.024
peptidyl amino acid modification GO:0018193 105 0.023
protein transport GO:0015031 155 0.023
response to external biotic stimulus GO:0043207 293 0.023
regulation of cell cycle phase transition GO:1901987 130 0.023
positive regulation of apoptotic process GO:0043065 47 0.023
Human
heart development GO:0007507 82 0.023
single organism catabolic process GO:0044712 228 0.023
ribose phosphate biosynthetic process GO:0046390 28 0.022
kidney development GO:0001822 3 0.022
positive regulation of gene expression GO:0010628 290 0.022
nucleotide metabolic process GO:0009117 161 0.022
positive regulation of hydrolase activity GO:0051345 78 0.022
Human
head development GO:0060322 135 0.022
negative regulation of rna biosynthetic process GO:1902679 240 0.022
organophosphate metabolic process GO:0019637 195 0.021
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.021
nucleoside phosphate biosynthetic process GO:1901293 34 0.020
negative regulation of biosynthetic process GO:0009890 277 0.020
tissue morphogenesis GO:0048729 297 0.020
hematopoietic or lymphoid organ development GO:0048534 57 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
cellular response to organic substance GO:0071310 132 0.020
Worm
organophosphate biosynthetic process GO:0090407 46 0.019
glycosyl compound metabolic process GO:1901657 127 0.019
establishment of protein localization GO:0045184 163 0.019
ribonucleoside monophosphate metabolic process GO:0009161 51 0.019
reactive oxygen species metabolic process GO:0072593 22 0.018
nucleotide biosynthetic process GO:0009165 34 0.018
open tracheal system development GO:0007424 204 0.018
negative regulation of transcription dna templated GO:0045892 237 0.018
regulation of rna splicing GO:0043484 69 0.018
regulation of immune system process GO:0002682 176 0.018
Human Mouse
positive regulation of cell migration GO:0030335 2 0.017
multi organism reproductive behavior GO:0044705 121 0.017
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.017
purine nucleotide biosynthetic process GO:0006164 29 0.017
response to biotic stimulus GO:0009607 294 0.017
Human
intracellular signal transduction GO:0035556 300 0.017
purine nucleoside monophosphate metabolic process GO:0009126 50 0.016
positive regulation of multicellular organism growth GO:0040018 21 0.016
rna interference GO:0016246 27 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
multi organism behavior GO:0051705 175 0.016
dna metabolic process GO:0006259 227 0.016
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
cell aging GO:0007569 2 0.016
response to oxygen containing compound GO:1901700 200 0.016
ribonucleoside monophosphate biosynthetic process GO:0009156 3 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.015
molting cycle GO:0042303 56 0.015
skin development GO:0043588 65 0.015
peptidyl lysine modification GO:0018205 57 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
epidermis development GO:0008544 65 0.015
negative regulation of gene expression GO:0010629 387 0.015
nucleoside monophosphate metabolic process GO:0009123 52 0.015
nucleoside metabolic process GO:0009116 127 0.015
single organism biosynthetic process GO:0044711 206 0.015
response to hypoxia GO:0001666 53 0.015
regulation of nucleotide metabolic process GO:0006140 62 0.015
respiratory system development GO:0060541 213 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
atp metabolic process GO:0046034 49 0.015
cellular catabolic process GO:0044248 372 0.015
energy taxis GO:0009453 21 0.014
spindle assembly GO:0051225 80 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
regulation of cell proliferation GO:0042127 163 0.013
rna splicing GO:0008380 83 0.013
tripartite regional subdivision GO:0007351 103 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
nephron development GO:0072006 3 0.013
organic substance catabolic process GO:1901575 308 0.013
male gamete generation GO:0048232 201 0.013
Fly
purine ribonucleoside metabolic process GO:0046128 127 0.013
regulation of molecular function GO:0065009 217 0.013
Human
anterior posterior pattern specification GO:0009952 136 0.013
positive regulation of response to stimulus GO:0048584 323 0.013
Human
response to other organism GO:0051707 293 0.013
regulation of catalytic activity GO:0050790 185 0.012
Human
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.012
immune response GO:0006955 246 0.012
Human
negative regulation of cellular metabolic process GO:0031324 382 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
cellular modified amino acid metabolic process GO:0006575 45 0.012
embryonic pattern specification GO:0009880 174 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
cell cycle phase transition GO:0044770 140 0.012
response to bacterium GO:0009617 198 0.011
oxoacid metabolic process GO:0043436 103 0.011
regulation of programmed cell death GO:0043067 152 0.011
Human
dna integrity checkpoint GO:0031570 81 0.011
cell cell junction assembly GO:0007043 38 0.011
macromolecular complex assembly GO:0065003 256 0.011
amine metabolic process GO:0009308 12 0.011
phosphorylation GO:0016310 294 0.011
regulation of response to stress GO:0080134 200 0.011
Human
positive regulation of cell motility GO:2000147 3 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
Human
dna biosynthetic process GO:0071897 24 0.011
chromatin organization GO:0006325 207 0.011
muscle tissue morphogenesis GO:0060415 2 0.011
negative regulation of phosphorylation GO:0042326 35 0.011
programmed cell death GO:0012501 257 0.011
Human
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.011
jnk cascade GO:0007254 50 0.010

Hsp60 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.061
inherited metabolic disorder DOID:655 0 0.056