Drosophila melanogaster

0 known processes

Traf-like (Dmel_CG4394)

TNF-receptor-associated factor-like

(Aliases: Traf3,Traf-related,TRAF3,dTRAF3,Dmel\CG4394,CG4394)

Traf-like biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule organizing center organization GO:0031023 168 0.665
growth GO:0040007 359 0.278
centrosome organization GO:0051297 163 0.240
negative regulation of developmental process GO:0051093 201 0.196
negative regulation of cellular biosynthetic process GO:0031327 277 0.185
centrosome duplication GO:0051298 121 0.173
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.162
purine containing compound metabolic process GO:0072521 155 0.158
organic substance catabolic process GO:1901575 308 0.150
small molecule metabolic process GO:0044281 305 0.138
ribonucleoside metabolic process GO:0009119 127 0.125
cellular catabolic process GO:0044248 372 0.117
centrosome cycle GO:0007098 137 0.116
catabolic process GO:0009056 409 0.113
negative regulation of cellular metabolic process GO:0031324 382 0.109
negative regulation of signal transduction GO:0009968 206 0.107
positive regulation of response to stimulus GO:0048584 323 0.100
positive regulation of gene expression GO:0010628 290 0.097
regulation of growth GO:0040008 233 0.095
ribose phosphate metabolic process GO:0019693 145 0.095
protein modification by small protein conjugation or removal GO:0070647 106 0.089
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.081
intracellular transport GO:0046907 228 0.078
nuclear division GO:0000280 332 0.072
death GO:0016265 284 0.071
single organism catabolic process GO:0044712 228 0.067
positive regulation of signaling GO:0023056 243 0.067
purine nucleotide metabolic process GO:0006163 146 0.067
stem cell maintenance GO:0019827 67 0.066
organelle assembly GO:0070925 198 0.066
purine ribonucleotide metabolic process GO:0009150 145 0.065
hematopoietic or lymphoid organ development GO:0048534 57 0.065
cellular macromolecule catabolic process GO:0044265 136 0.064
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.062
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.060
cellular response to external stimulus GO:0071496 66 0.059
carbohydrate derivative metabolic process GO:1901135 217 0.059
regulation of reactive oxygen species metabolic process GO:2000377 8 0.058
stem cell differentiation GO:0048863 117 0.058
negative regulation of cell communication GO:0010648 223 0.058
digestive tract morphogenesis GO:0048546 127 0.056
cellular protein modification process GO:0006464 438 0.054
negative regulation of biosynthetic process GO:0009890 277 0.053
ubiquitin dependent protein catabolic process GO:0006511 78 0.053
nucleotide metabolic process GO:0009117 161 0.053
protein ubiquitination GO:0016567 70 0.053
negative regulation of rna biosynthetic process GO:1902679 240 0.053
negative regulation of signaling GO:0023057 219 0.053
protein modification by small protein conjugation GO:0032446 79 0.052
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.052
purine ribonucleotide biosynthetic process GO:0009152 28 0.051
negative regulation of transcription dna templated GO:0045892 237 0.050
cyclic nucleotide metabolic process GO:0009187 28 0.050
cell maturation GO:0048469 144 0.050
imaginal disc derived wing morphogenesis GO:0007476 337 0.050
organelle fusion GO:0048284 46 0.048
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.048
single organism membrane organization GO:0044802 93 0.048
response to reactive oxygen species GO:0000302 24 0.048
negative regulation of response to stimulus GO:0048585 258 0.047
negative regulation of nucleic acid templated transcription GO:1903507 240 0.045
intracellular signal transduction GO:0035556 300 0.045
cellular protein catabolic process GO:0044257 83 0.044
single organism biosynthetic process GO:0044711 206 0.044
muscle structure development GO:0061061 224 0.044
regulation of protein metabolic process GO:0051246 256 0.043
organonitrogen compound metabolic process GO:1901564 318 0.043
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.042
developmental maturation GO:0021700 172 0.042
purine nucleoside metabolic process GO:0042278 127 0.042
nucleoside triphosphate metabolic process GO:0009141 120 0.042
digestive tract development GO:0048565 149 0.042
secretion GO:0046903 109 0.041
endosomal transport GO:0016197 44 0.041
asymmetric neuroblast division GO:0055059 33 0.041
negative regulation of molecular function GO:0044092 51 0.041
negative regulation of multicellular organismal process GO:0051241 142 0.041
protein modification process GO:0036211 438 0.041
hemopoiesis GO:0030097 46 0.040
nucleoside phosphate metabolic process GO:0006753 162 0.039
organelle fission GO:0048285 340 0.039
glial cell migration GO:0008347 31 0.038
immune system development GO:0002520 57 0.038
localization of cell GO:0051674 257 0.038
carbohydrate derivative catabolic process GO:1901136 118 0.038
positive regulation of immune system process GO:0002684 68 0.037
modification dependent macromolecule catabolic process GO:0043632 79 0.037
positive regulation of cell communication GO:0010647 250 0.036
cellular response to nutrient levels GO:0031669 62 0.036
defense response GO:0006952 300 0.035
chaeta development GO:0022416 97 0.035
regulation of nervous system development GO:0051960 248 0.034
stem cell development GO:0048864 79 0.034
positive regulation of signal transduction GO:0009967 223 0.034
cell migration GO:0016477 238 0.033
organophosphate metabolic process GO:0019637 195 0.032
cellular response to dna damage stimulus GO:0006974 223 0.032
regulation of catalytic activity GO:0050790 185 0.031
stem cell division GO:0017145 69 0.031
ribonucleotide metabolic process GO:0009259 145 0.031
organonitrogen compound catabolic process GO:1901565 128 0.031
aromatic compound catabolic process GO:0019439 166 0.031
membrane fusion GO:0061025 42 0.030
protein catabolic process GO:0030163 101 0.030
sensory organ morphogenesis GO:0090596 260 0.030
regulation of intracellular signal transduction GO:1902531 236 0.030
cell motility GO:0048870 251 0.029
ribonucleoside triphosphate metabolic process GO:0009199 119 0.029
nucleoside triphosphate catabolic process GO:0009143 108 0.029
immune response regulating signaling pathway GO:0002764 2 0.029
programmed cell death GO:0012501 257 0.029
response to lipopolysaccharide GO:0032496 4 0.029
appendage morphogenesis GO:0035107 397 0.028
protein phosphorylation GO:0006468 169 0.028
modification dependent protein catabolic process GO:0019941 78 0.028
synaptic transmission GO:0007268 288 0.027
regulation of cellular protein metabolic process GO:0032268 243 0.027
forebrain development GO:0030900 2 0.027
phosphorylation GO:0016310 294 0.027
multicellular organismal aging GO:0010259 140 0.027
immune system process GO:0002376 347 0.026
ethanolamine containing compound metabolic process GO:0042439 4 0.026
appendage development GO:0048736 401 0.026
trachea development GO:0060438 29 0.026
regulation of cell differentiation GO:0045595 302 0.026
limb development GO:0060173 1 0.025
reactive oxygen species metabolic process GO:0072593 22 0.025
cell division GO:0051301 248 0.025
membrane organization GO:0061024 112 0.025
regulation of phosphorylation GO:0042325 147 0.025
negative regulation of rna metabolic process GO:0051253 251 0.025
transcription from rna polymerase ii promoter GO:0006366 368 0.025
regulation of immune system process GO:0002682 176 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.025
purine nucleotide catabolic process GO:0006195 109 0.025
cell fate determination GO:0001709 91 0.024
regulation of cell substrate adhesion GO:0010810 2 0.024
immune effector process GO:0002252 98 0.024
negative regulation of cell differentiation GO:0045596 143 0.024
mitotic nuclear division GO:0007067 213 0.024
ribonucleoside monophosphate metabolic process GO:0009161 51 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
central nervous system development GO:0007417 201 0.024
purine ribonucleoside catabolic process GO:0046130 112 0.024
purine nucleoside triphosphate metabolic process GO:0009144 119 0.024
response to oxidative stress GO:0006979 86 0.024
regulation of synapse organization GO:0050807 110 0.024
positive regulation of programmed cell death GO:0043068 62 0.024
regulation of cell cycle GO:0051726 291 0.023
apoptotic process GO:0006915 159 0.023
multicellular organism growth GO:0035264 46 0.023
digestive system development GO:0055123 149 0.023
cyclic purine nucleotide metabolic process GO:0052652 25 0.023
tube development GO:0035295 244 0.023
proteasomal protein catabolic process GO:0010498 59 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
connective tissue development GO:0061448 3 0.022
phototaxis GO:0042331 21 0.022
embryonic morphogenesis GO:0048598 206 0.022
organic substance transport GO:0071702 257 0.022
proteolysis GO:0006508 192 0.022
nucleotide biosynthetic process GO:0009165 34 0.022
positive regulation of macromolecule metabolic process GO:0010604 405 0.022
somatic stem cell division GO:0048103 37 0.021
phosphatidylethanolamine metabolic process GO:0046337 1 0.021
g protein coupled receptor signaling pathway GO:0007186 136 0.021
ribonucleotide biosynthetic process GO:0009260 28 0.021
wing disc morphogenesis GO:0007472 344 0.021
secretion by cell GO:0032940 101 0.021
positive regulation of cell migration GO:0030335 2 0.021
macromolecule catabolic process GO:0009057 161 0.021
guanosine containing compound catabolic process GO:1901069 74 0.021
carbohydrate metabolic process GO:0005975 82 0.021
phagocytosis GO:0006909 215 0.020
gland development GO:0048732 191 0.020
regulation of cell cycle process GO:0010564 181 0.020
heterocycle catabolic process GO:0046700 166 0.020
regulation of cell proliferation GO:0042127 163 0.020
amine metabolic process GO:0009308 12 0.019
regulation of catabolic process GO:0009894 170 0.019
biological adhesion GO:0022610 138 0.019
lipid localization GO:0010876 54 0.019
purine ribonucleoside metabolic process GO:0046128 127 0.019
post embryonic appendage morphogenesis GO:0035120 385 0.019
oocyte development GO:0048599 124 0.019
response to hexose GO:0009746 3 0.019
negative regulation of cell proliferation GO:0008285 69 0.019
nucleoside phosphate biosynthetic process GO:1901293 34 0.019
actin filament based process GO:0030029 220 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.019
gliogenesis GO:0042063 80 0.019
negative regulation of developmental growth GO:0048640 64 0.019
cellular response to hexose stimulus GO:0071331 1 0.019
maintenance of location GO:0051235 73 0.018
purine containing compound biosynthetic process GO:0072522 30 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
positive regulation of apoptotic process GO:0043065 47 0.018
centriole replication GO:0007099 24 0.018
cgmp metabolic process GO:0046068 11 0.018
regulation of anatomical structure morphogenesis GO:0022603 242 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.018
regulation of cell morphogenesis GO:0022604 163 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.018
cellular response to lipopolysaccharide GO:0071222 3 0.018
cell cell junction organization GO:0045216 55 0.018
synapse organization GO:0050808 196 0.017
mesenchymal cell development GO:0014031 1 0.017
regulation of synapse structure and activity GO:0050803 128 0.017
regulation of molecular function GO:0065009 217 0.017
response to wounding GO:0009611 94 0.017
regulation of hydrolase activity GO:0051336 97 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.017
cell proliferation GO:0008283 299 0.017
regulation of rna splicing GO:0043484 69 0.017
organic cyclic compound catabolic process GO:1901361 168 0.016
regulation of translation GO:0006417 56 0.016
energy taxis GO:0009453 21 0.016
germ line stem cell maintenance GO:0030718 50 0.016
positive regulation of phosphorylation GO:0042327 87 0.016
negative regulation of insulin secretion GO:0046676 1 0.016
positive regulation of cell death GO:0010942 69 0.016
synapse assembly GO:0007416 143 0.016
immune response activating signal transduction GO:0002757 2 0.016
response to extracellular stimulus GO:0009991 116 0.016
positive regulation of cell motility GO:2000147 3 0.016
gland morphogenesis GO:0022612 145 0.016
camera type eye development GO:0043010 4 0.015
centriole assembly GO:0098534 24 0.015
nucleoside metabolic process GO:0009116 127 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
rna processing GO:0006396 147 0.015
hindbrain development GO:0030902 2 0.015
neuromuscular junction development GO:0007528 149 0.015
regulation of epithelial cell proliferation GO:0050678 4 0.015
determination of adult lifespan GO:0008340 137 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
telencephalon development GO:0021537 2 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
positive regulation of molecular function GO:0044093 136 0.015
neuronal stem cell division GO:0036445 35 0.015
substrate adhesion dependent cell spreading GO:0034446 2 0.015
negative regulation of catalytic activity GO:0043086 42 0.015
ras protein signal transduction GO:0007265 88 0.015
secondary metabolic process GO:0019748 75 0.015
regulation of autophagy GO:0010506 62 0.015
protein localization GO:0008104 284 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
leg disc morphogenesis GO:0007478 80 0.015
gtp metabolic process GO:0046039 72 0.014
oocyte dorsal ventral axis specification GO:0007310 34 0.014
eye development GO:0001654 323 0.014
negative regulation of growth GO:0045926 84 0.014
kidney development GO:0001822 3 0.014
peptidyl threonine phosphorylation GO:0018107 2 0.014
cyclic nucleotide biosynthetic process GO:0009190 25 0.014
purine containing compound catabolic process GO:0072523 112 0.014
cell growth GO:0016049 108 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
negative regulation of cellular component organization GO:0051129 108 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
sterol homeostasis GO:0055092 4 0.014
hair cell differentiation GO:0035315 47 0.014
glycosyl compound catabolic process GO:1901658 112 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
neuromuscular synaptic transmission GO:0007274 67 0.014
protein import into nucleus GO:0006606 51 0.014
salivary gland morphogenesis GO:0007435 145 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
organophosphate catabolic process GO:0046434 112 0.013
oocyte construction GO:0007308 112 0.013
somatic muscle development GO:0007525 66 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
ameboidal type cell migration GO:0001667 151 0.013
organophosphate biosynthetic process GO:0090407 46 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
homeostatic process GO:0042592 199 0.013
autophagic cell death GO:0048102 83 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
cellularization GO:0007349 90 0.013
male meiosis GO:0007140 52 0.013
response to decreased oxygen levels GO:0036293 58 0.013
response to glucose GO:0009749 2 0.013
genital disc development GO:0035215 44 0.013
cell death GO:0008219 279 0.013
epidermis development GO:0008544 65 0.013
negative regulation of gene expression GO:0010629 387 0.013
regulation of cellular component biogenesis GO:0044087 201 0.012
response to radiation GO:0009314 155 0.012
regulation of secretion by cell GO:1903530 39 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
negative regulation of epithelial cell proliferation GO:0050680 4 0.012
regulation of neurogenesis GO:0050767 158 0.012
anatomical structure homeostasis GO:0060249 97 0.012
l amino acid import GO:0043092 2 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
regulation of locomotion GO:0040012 42 0.012
regulation of blood circulation GO:1903522 21 0.012
smoothened signaling pathway GO:0007224 49 0.012
neuroblast division GO:0055057 35 0.012
germline ring canal formation GO:0030725 13 0.012
regulation of mitosis GO:0007088 56 0.012
cellular response to monosaccharide stimulus GO:0071326 2 0.012
regulation of lipid transport GO:0032368 3 0.012
translation GO:0006412 69 0.012
pigmentation GO:0043473 75 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
meiotic chromosome segregation GO:0045132 59 0.012
monocarboxylic acid transport GO:0015718 3 0.012
regulation of cyclic nucleotide biosynthetic process GO:0030802 13 0.012
response to monosaccharide GO:0034284 4 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
cholesterol homeostasis GO:0042632 3 0.011
endosome organization GO:0007032 9 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
cellular response to radiation GO:0071478 52 0.011
hormone catabolic process GO:0042447 3 0.011
limb morphogenesis GO:0035108 1 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
ribose phosphate biosynthetic process GO:0046390 28 0.011
retina development in camera type eye GO:0060041 4 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
compound eye morphogenesis GO:0001745 249 0.011
regulation of mrna splicing via spliceosome GO:0048024 64 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
organic acid metabolic process GO:0006082 103 0.011
organic hydroxy compound metabolic process GO:1901615 83 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
glycerolipid catabolic process GO:0046503 3 0.011
peptidyl tyrosine phosphorylation GO:0018108 24 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
endocytosis GO:0006897 310 0.011
melanin metabolic process GO:0006582 47 0.011
compound eye development GO:0048749 307 0.011
synaptic vesicle exocytosis GO:0016079 16 0.011
regulation of cell adhesion GO:0030155 27 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
response to oxygen containing compound GO:1901700 200 0.011
nucleoside monophosphate metabolic process GO:0009123 52 0.011
regulation of cellular localization GO:0060341 136 0.011
reproductive structure development GO:0048608 74 0.011
adherens junction organization GO:0034332 27 0.011
mrna processing GO:0006397 104 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
response to hypoxia GO:0001666 53 0.011
negative regulation of immune system process GO:0002683 50 0.010
response to organophosphorus GO:0046683 2 0.010
protein k48 linked ubiquitination GO:0070936 3 0.010
epiboly GO:0090504 2 0.010
regulation of cell death GO:0010941 173 0.010
lipid storage GO:0019915 38 0.010
microtubule based movement GO:0007018 51 0.010
glandular epithelial cell differentiation GO:0002067 1 0.010
axonogenesis GO:0007409 290 0.010
positive regulation of protein modification process GO:0031401 58 0.010
cellular macromolecule localization GO:0070727 220 0.010
regulation of microtubule cytoskeleton organization GO:0070507 41 0.010
skin development GO:0043588 65 0.010

Traf-like disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
disease of metabolism DOID:0014667 0 0.032
inherited metabolic disorder DOID:655 0 0.028
nervous system disease DOID:863 0 0.023
diabetes mellitus DOID:9351 0 0.020
type 2 diabetes mellitus DOID:9352 0 0.020
carbohydrate metabolism disease DOID:0050013 0 0.020
glucose metabolism disease DOID:4194 0 0.020
acquired metabolic disease DOID:0060158 0 0.020
central nervous system disease DOID:331 0 0.015
disease of cellular proliferation DOID:14566 0 0.011