Drosophila melanogaster

0 known processes

wdn (Dmel_CG1454)

wings down

(Aliases: sry-h1,sry-c,Sryc,pqp,Dmel\CG1454,sry h-l,CG1454)

wdn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin modification GO:0016568 147 0.404
imaginal disc derived appendage development GO:0048737 399 0.384
post embryonic appendage morphogenesis GO:0035120 385 0.287
eye development GO:0001654 323 0.287
chromosome organization GO:0051276 360 0.276
appendage development GO:0048736 401 0.260
appendage morphogenesis GO:0035107 397 0.254
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.234
female meiotic division GO:0007143 70 0.233
chromatin organization GO:0006325 207 0.232
imaginal disc derived appendage morphogenesis GO:0035114 395 0.230
positive regulation of rna metabolic process GO:0051254 271 0.230
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.212
negative regulation of signaling GO:0023057 219 0.206
response to abiotic stimulus GO:0009628 341 0.189
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.188
organelle fission GO:0048285 340 0.185
transcription from rna polymerase ii promoter GO:0006366 368 0.181
nuclear division GO:0000280 332 0.179
positive regulation of transcription dna templated GO:0045893 266 0.164
response to organic substance GO:0010033 284 0.159
positive regulation of rna biosynthetic process GO:1902680 266 0.152
positive regulation of macromolecule metabolic process GO:0010604 405 0.149
dna metabolic process GO:0006259 227 0.145
localization of cell GO:0051674 257 0.142
positive regulation of cellular biosynthetic process GO:0031328 316 0.141
catabolic process GO:0009056 409 0.135
negative regulation of gene expression GO:0010629 387 0.135
positive regulation of nucleic acid templated transcription GO:1903508 266 0.131
mrna metabolic process GO:0016071 124 0.127
response to oxygen containing compound GO:1901700 200 0.122
spindle organization GO:0007051 253 0.120
negative regulation of mitotic cell cycle GO:0045930 109 0.118
histone modification GO:0016570 106 0.116
positive regulation of gene expression GO:0010628 290 0.112
organophosphate metabolic process GO:0019637 195 0.112
peptidyl lysine modification GO:0018205 57 0.111
columnar cuboidal epithelial cell development GO:0002066 249 0.108
response to radiation GO:0009314 155 0.106
regulation of intracellular signal transduction GO:1902531 236 0.105
cell division GO:0051301 248 0.103
organonitrogen compound metabolic process GO:1901564 318 0.101
histone acetylation GO:0016573 38 0.100
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.099
chromosome segregation GO:0007059 157 0.097
ribonucleoside triphosphate metabolic process GO:0009199 119 0.097
chromatin silencing GO:0006342 76 0.097
positive regulation of biosynthetic process GO:0009891 316 0.096
cellular response to organic substance GO:0071310 132 0.095
imaginal disc derived wing morphogenesis GO:0007476 337 0.094
establishment of localization in cell GO:0051649 402 0.092
negative regulation of cell communication GO:0010648 223 0.091
nucleobase containing small molecule metabolic process GO:0055086 174 0.090
wing disc morphogenesis GO:0007472 344 0.090
nucleoside phosphate metabolic process GO:0006753 162 0.089
nucleotide metabolic process GO:0009117 161 0.088
internal protein amino acid acetylation GO:0006475 38 0.087
purine nucleotide metabolic process GO:0006163 146 0.087
intracellular signal transduction GO:0035556 300 0.086
chromatin remodeling GO:0006338 72 0.085
cell migration GO:0016477 238 0.085
negative regulation of gene expression epigenetic GO:0045814 77 0.085
cellular response to chemical stimulus GO:0070887 199 0.084
response to endogenous stimulus GO:0009719 119 0.083
single organism catabolic process GO:0044712 228 0.081
purine nucleoside triphosphate metabolic process GO:0009144 119 0.080
internal peptidyl lysine acetylation GO:0018393 38 0.079
negative regulation of biosynthetic process GO:0009890 277 0.079
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.079
organonitrogen compound catabolic process GO:1901565 128 0.079
tube development GO:0035295 244 0.078
sex differentiation GO:0007548 81 0.078
ribonucleotide metabolic process GO:0009259 145 0.077
covalent chromatin modification GO:0016569 106 0.077
dna repair GO:0006281 54 0.077
establishment or maintenance of cell polarity GO:0007163 167 0.076
meiotic nuclear division GO:0007126 151 0.075
glycosyl compound metabolic process GO:1901657 127 0.075
organic substance catabolic process GO:1901575 308 0.075
regulation of phosphorus metabolic process GO:0051174 210 0.073
double strand break repair GO:0006302 26 0.072
digestive system development GO:0055123 149 0.071
meiotic cell cycle process GO:1903046 132 0.070
protein complex biogenesis GO:0070271 201 0.070
negative regulation of response to stimulus GO:0048585 258 0.069
organic acid metabolic process GO:0006082 103 0.066
camera type eye morphogenesis GO:0048593 2 0.066
protein acylation GO:0043543 42 0.066
nucleoside triphosphate metabolic process GO:0009141 120 0.066
homeostatic process GO:0042592 199 0.065
cellular macromolecular complex assembly GO:0034622 153 0.064
negative regulation of cellular metabolic process GO:0031324 382 0.064
negative regulation of transcription dna templated GO:0045892 237 0.064
ras protein signal transduction GO:0007265 88 0.064
response to light stimulus GO:0009416 124 0.063
reproductive structure development GO:0048608 74 0.063
purine nucleoside metabolic process GO:0042278 127 0.063
cellular response to dna damage stimulus GO:0006974 223 0.063
mitotic cell cycle phase transition GO:0044772 138 0.063
regulation of cell cycle process GO:0010564 181 0.062
ribose phosphate metabolic process GO:0019693 145 0.061
vesicle mediated transport GO:0016192 381 0.061
mitotic nuclear division GO:0007067 213 0.060
regulation of mitotic cell cycle GO:0007346 190 0.060
regulation of mitotic cell cycle phase transition GO:1901990 130 0.060
regulation of cellular protein metabolic process GO:0032268 243 0.060
synaptic transmission GO:0007268 288 0.059
macromolecular complex assembly GO:0065003 256 0.059
cellular response to radiation GO:0071478 52 0.058
positive regulation of cellular protein metabolic process GO:0032270 118 0.058
purine ribonucleoside metabolic process GO:0046128 127 0.058
male gamete generation GO:0048232 201 0.057
small molecule metabolic process GO:0044281 305 0.057
heterocycle catabolic process GO:0046700 166 0.056
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.056
cell motility GO:0048870 251 0.055
negative regulation of cell cycle process GO:0010948 109 0.055
single organism cellular localization GO:1902580 180 0.054
negative regulation of signal transduction GO:0009968 206 0.054
protein modification process GO:0036211 438 0.054
regulation of cellular amino acid metabolic process GO:0006521 0 0.053
positive regulation of phosphorus metabolic process GO:0010562 139 0.053
meiotic cell cycle GO:0051321 171 0.053
regulation of phosphate metabolic process GO:0019220 210 0.053
aromatic compound catabolic process GO:0019439 166 0.053
camera type eye development GO:0043010 4 0.052
rna localization GO:0006403 115 0.051
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.050
single organism biosynthetic process GO:0044711 206 0.050
regulation of phosphorylation GO:0042325 147 0.049
spermatogenesis GO:0007283 200 0.048
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.047
mrna splicing via spliceosome GO:0000398 73 0.046
leg disc development GO:0035218 92 0.046
tube morphogenesis GO:0035239 191 0.044
regulation of localization GO:0032879 275 0.044
response to nitrogen compound GO:1901698 90 0.044
purine ribonucleotide metabolic process GO:0009150 145 0.043
defense response GO:0006952 300 0.043
positive regulation of catabolic process GO:0009896 105 0.043
spermatid development GO:0007286 98 0.043
macromolecule catabolic process GO:0009057 161 0.043
regulation of cell cycle GO:0051726 291 0.043
guanosine containing compound metabolic process GO:1901068 74 0.043
organic cyclic compound catabolic process GO:1901361 168 0.042
regulation of developmental growth GO:0048638 174 0.042
dna recombination GO:0006310 32 0.042
purine containing compound metabolic process GO:0072521 155 0.042
regulation of small gtpase mediated signal transduction GO:0051056 93 0.042
oxoacid metabolic process GO:0043436 103 0.042
negative regulation of nucleic acid templated transcription GO:1903507 240 0.041
actin cytoskeleton organization GO:0030036 206 0.041
cell proliferation GO:0008283 299 0.041
peptidyl lysine acetylation GO:0018394 39 0.041
rna splicing via transesterification reactions GO:0000375 73 0.039
protein complex assembly GO:0006461 200 0.039
carbohydrate derivative metabolic process GO:1901135 217 0.039
mitotic cell cycle checkpoint GO:0007093 88 0.039
imaginal disc derived leg morphogenesis GO:0007480 80 0.038
neuroblast proliferation GO:0007405 74 0.038
centrosome organization GO:0051297 163 0.037
protein phosphorylation GO:0006468 169 0.037
cellular protein modification process GO:0006464 438 0.037
phosphorylation GO:0016310 294 0.037
response to biotic stimulus GO:0009607 294 0.037
cell cycle phase transition GO:0044770 140 0.037
spermatid differentiation GO:0048515 114 0.037
regulation of cell cycle phase transition GO:1901987 130 0.037
regulation of cellular catabolic process GO:0031329 157 0.037
nucleotide catabolic process GO:0009166 109 0.036
growth GO:0040007 359 0.036
embryonic development via the syncytial blastoderm GO:0001700 148 0.036
organelle localization GO:0051640 148 0.035
male sex differentiation GO:0046661 25 0.034
centrosome cycle GO:0007098 137 0.034
chemosensory behavior GO:0007635 106 0.034
digestive tract morphogenesis GO:0048546 127 0.034
regulation of ras protein signal transduction GO:0046578 93 0.033
small gtpase mediated signal transduction GO:0007264 88 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.033
negative regulation of rna metabolic process GO:0051253 251 0.033
mitotic sister chromatid segregation GO:0000070 87 0.032
regulation of molecular function GO:0065009 217 0.032
defense response to other organism GO:0098542 225 0.032
regulation of organelle organization GO:0033043 196 0.032
positive regulation of cell communication GO:0010647 250 0.032
regulation of protein metabolic process GO:0051246 256 0.032
cell death GO:0008219 279 0.031
protein localization GO:0008104 284 0.031
response to external biotic stimulus GO:0043207 293 0.031
somatic stem cell division GO:0048103 37 0.031
regulation of mapk cascade GO:0043408 92 0.031
regulation of protein modification process GO:0031399 112 0.030
death GO:0016265 284 0.030
ribonucleotide catabolic process GO:0009261 109 0.030
leg disc morphogenesis GO:0007478 80 0.030
mitotic spindle organization GO:0007052 220 0.030
developmental growth GO:0048589 280 0.029
response to other organism GO:0051707 293 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.029
embryonic morphogenesis GO:0048598 206 0.028
regulation of catabolic process GO:0009894 170 0.028
lipid metabolic process GO:0006629 121 0.028
positive regulation of signal transduction GO:0009967 223 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.028
cellularization GO:0007349 90 0.027
intracellular transport GO:0046907 228 0.027
development of primary sexual characteristics GO:0045137 50 0.027
positive regulation of phosphorylation GO:0042327 87 0.027
single organism intracellular transport GO:1902582 207 0.026
epithelial cell development GO:0002064 274 0.026
positive regulation of phosphate metabolic process GO:0045937 139 0.026
response to lipid GO:0033993 38 0.026
carbohydrate derivative catabolic process GO:1901136 118 0.026
cellular nitrogen compound catabolic process GO:0044270 165 0.026
dendrite morphogenesis GO:0048813 199 0.026
nucleoside metabolic process GO:0009116 127 0.026
carboxylic acid metabolic process GO:0019752 92 0.026
actin filament based process GO:0030029 220 0.025
regulation of mrna splicing via spliceosome GO:0048024 64 0.025
establishment of organelle localization GO:0051656 122 0.025
nucleobase containing compound catabolic process GO:0034655 165 0.025
nucleoside triphosphate catabolic process GO:0009143 108 0.024
purine nucleotide catabolic process GO:0006195 109 0.024
microtubule organizing center organization GO:0031023 168 0.024
axonogenesis GO:0007409 290 0.024
cellular response to endogenous stimulus GO:0071495 80 0.024
regulation of catalytic activity GO:0050790 185 0.024
organic substance transport GO:0071702 257 0.024
positive regulation of protein metabolic process GO:0051247 128 0.024
cellular response to oxygen containing compound GO:1901701 79 0.023
dendrite development GO:0016358 204 0.023
protein acetylation GO:0006473 39 0.023
regulation of chromosome organization GO:0033044 64 0.023
cellular protein complex assembly GO:0043623 71 0.023
peptidyl amino acid modification GO:0018193 105 0.023
regulation of immune system process GO:0002682 176 0.023
negative regulation of intracellular signal transduction GO:1902532 57 0.023
response to hormone GO:0009725 45 0.023
male gonad development GO:0008584 9 0.023
response to organic cyclic compound GO:0014070 89 0.022
purine ribonucleoside catabolic process GO:0046130 112 0.022
regulation of mrna processing GO:0050684 71 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.022
cellular macromolecule localization GO:0070727 220 0.022
establishment of cell polarity GO:0030010 40 0.022
stem cell proliferation GO:0072089 88 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.022
cytoplasmic transport GO:0016482 130 0.022
erk1 and erk2 cascade GO:0070371 39 0.022
endocytosis GO:0006897 310 0.022
purine containing compound catabolic process GO:0072523 112 0.022
apoptotic process GO:0006915 159 0.021
negative regulation of rna biosynthetic process GO:1902679 240 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.021
neuronal stem cell division GO:0036445 35 0.021
modification dependent macromolecule catabolic process GO:0043632 79 0.021
positive regulation of nucleotide metabolic process GO:0045981 55 0.021
protein ubiquitination GO:0016567 70 0.021
organic hydroxy compound metabolic process GO:1901615 83 0.021
cellular macromolecule catabolic process GO:0044265 136 0.021
spindle assembly GO:0051225 80 0.020
nucleoside phosphate catabolic process GO:1901292 110 0.020
positive regulation of signaling GO:0023056 243 0.020
compound eye development GO:0048749 307 0.020
single organism behavior GO:0044708 391 0.020
chemical homeostasis GO:0048878 92 0.020
cellular catabolic process GO:0044248 372 0.020
regulation of growth GO:0040008 233 0.020
cellular response to light stimulus GO:0071482 37 0.020
embryo development ending in birth or egg hatching GO:0009792 152 0.020
digestive tract development GO:0048565 149 0.020
cellular response to biotic stimulus GO:0071216 4 0.019
establishment of protein localization GO:0045184 163 0.019
regulation of gene silencing GO:0060968 63 0.018
body morphogenesis GO:0010171 2 0.018
phagocytosis GO:0006909 215 0.018
organophosphate catabolic process GO:0046434 112 0.018
cellular response to hormone stimulus GO:0032870 44 0.018
ribonucleoside metabolic process GO:0009119 127 0.018
ribonucleoside triphosphate catabolic process GO:0009203 108 0.018
response to uv GO:0009411 24 0.017
response to temperature stimulus GO:0009266 106 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
cellular ketone metabolic process GO:0042180 24 0.017
positive regulation of cellular catabolic process GO:0031331 95 0.017
chaeta development GO:0022416 97 0.017
cellular amine metabolic process GO:0044106 12 0.017
positive regulation of gene expression epigenetic GO:0045815 16 0.016
positive regulation of organelle organization GO:0010638 65 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.016
regulation of cellular localization GO:0060341 136 0.016
regulation of nucleotide metabolic process GO:0006140 62 0.016
g2 dna damage checkpoint GO:0031572 69 0.016
protein modification by small protein conjugation GO:0032446 79 0.016
defense response to bacterium GO:0042742 178 0.016
mitotic g2 dna damage checkpoint GO:0007095 69 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
positive regulation of cellular component organization GO:0051130 156 0.016
photoreceptor cell differentiation GO:0046530 170 0.016
glycosyl compound catabolic process GO:1901658 112 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
regulation of transferase activity GO:0051338 58 0.015
dna biosynthetic process GO:0071897 24 0.015
regulation of system process GO:0044057 36 0.015
cell fate determination GO:0001709 91 0.015
nucleocytoplasmic transport GO:0006913 72 0.015
regulation of cytoskeleton organization GO:0051493 89 0.015
apoptotic signaling pathway GO:0097190 27 0.015
regulation of cell differentiation GO:0045595 302 0.015
nucleoside catabolic process GO:0009164 112 0.014
anterior posterior pattern specification GO:0009952 136 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
sister chromatid segregation GO:0000819 92 0.014
cellular response to uv GO:0034644 12 0.014
regulation of erk1 and erk2 cascade GO:0070372 39 0.014
chromosome condensation GO:0030261 41 0.014
eye morphogenesis GO:0048592 260 0.014
neural precursor cell proliferation GO:0061351 75 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
signal transduction by phosphorylation GO:0023014 107 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.013
negative regulation of cell cycle GO:0045786 116 0.013
regulation of purine nucleotide metabolic process GO:1900542 62 0.013
taxis GO:0042330 304 0.013
regulation of blood circulation GO:1903522 21 0.013
regulation of dna metabolic process GO:0051052 34 0.013
regulation of transport GO:0051049 181 0.013
mrna processing GO:0006397 104 0.013
negative regulation of phosphate metabolic process GO:0045936 45 0.013
intracellular protein transport GO:0006886 104 0.013
mapk cascade GO:0000165 107 0.013
protein dna complex subunit organization GO:0071824 86 0.013
respiratory system development GO:0060541 213 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
mitotic dna integrity checkpoint GO:0044774 75 0.013
response to bacterium GO:0009617 198 0.013
modification dependent protein catabolic process GO:0019941 78 0.013
aging GO:0007568 143 0.012
meiotic chromosome segregation GO:0045132 59 0.012
olfactory behavior GO:0042048 97 0.012
secretion GO:0046903 109 0.012
regulation of anatomical structure size GO:0090066 163 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
synapse organization GO:0050808 196 0.012
axon guidance GO:0007411 233 0.012
eggshell formation GO:0030703 105 0.012
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.012
centrosome duplication GO:0051298 121 0.012
eggshell chorion assembly GO:0007306 66 0.012
rna processing GO:0006396 147 0.012
single organism nuclear import GO:1902593 51 0.012
acid secretion GO:0046717 1 0.012
nucleoside monophosphate metabolic process GO:0009123 52 0.012
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.012
neurological system process GO:0050877 358 0.012
positive regulation of protein modification process GO:0031401 58 0.012
reproductive system development GO:0061458 74 0.012
cell recognition GO:0008037 102 0.012
defense response to gram negative bacterium GO:0050829 94 0.011
gastrulation involving germ band extension GO:0010004 36 0.011
heterochromatin organization involved in chromatin silencing GO:0070868 9 0.011
cell maturation GO:0048469 144 0.011
tissue morphogenesis GO:0048729 297 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
morphogenesis of embryonic epithelium GO:0016331 94 0.011
regulation of protein catabolic process GO:0042176 55 0.011
cellular response to abiotic stimulus GO:0071214 58 0.011
regulation of cell proliferation GO:0042127 163 0.011
regulation of cellular component size GO:0032535 98 0.011
ribonucleoprotein complex biogenesis GO:0022613 31 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
sensory organ morphogenesis GO:0090596 260 0.011
regulation of response to stress GO:0080134 200 0.011
jnk cascade GO:0007254 50 0.011
multi organism reproductive behavior GO:0044705 121 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
ribonucleoprotein complex subunit organization GO:0071826 28 0.010
immune effector process GO:0002252 98 0.010
connective tissue development GO:0061448 3 0.010
rna 3 end processing GO:0031123 45 0.010
mitotic g2 m transition checkpoint GO:0044818 70 0.010
lipid homeostasis GO:0055088 33 0.010
guanosine containing compound catabolic process GO:1901069 74 0.010
biological adhesion GO:0022610 138 0.010
protein catabolic process GO:0030163 101 0.010
cellular response to nitrogen compound GO:1901699 51 0.010
asymmetric stem cell division GO:0098722 49 0.010
cellular protein catabolic process GO:0044257 83 0.010
central nervous system development GO:0007417 201 0.010
amine metabolic process GO:0009308 12 0.010

wdn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
disease of cellular proliferation DOID:14566 0 0.032
cancer DOID:162 0 0.027
organ system cancer DOID:0050686 0 0.027
nervous system disease DOID:863 0 0.021